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Arthritis Research & Therapy publishes selected collections of research articles, conference proceedings, reviews and reports as supplements, which are free to access online. All articles published in supplements are subject to peer review; meeting abstracts undergo review and selection by the conference. Find out more about publishing a supplement with BioMed Central.

Volume 7 Supplement 1

25th European Workshop for Rheumatology Research

Meeting abstracts

25th European Workshop for Rheumatology Research

Glasgow, UK

24-27 February 2005

The organizer would like to thank the following companies who have generously supported the meeting: Abbott Immunology (Main sponsor), Bristol-Myers Squibb, Schering-Plough, Wyeth, AstraZeneca, MSD, Amgen

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Stem cells now and in the future in medicine

A Smith Arthritis Research & Therapy 2005, 7(Suppl 1):S1 (17 February 2005)

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Chaperonins and the regulation of immunity

GS Panayi, VC Corrigall Arthritis Research & Therapy 2005, 7(Suppl 1):S2 (17 February 2005)

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Autoimmune diabetes: mechanisms

A Cooke Arthritis Research & Therapy 2005, 7(Suppl 1):S3 (17 February 2005)

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Autoimmunity or immune deficiency? On the role and function of regulatory T cells in chronic arthritis

BJ Prakken, I de Kleer Arthritis Research & Therapy 2005, 7(Suppl 1):S4 (17 February 2005)

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Tracking immune responses in vivo

MK Jenkins Arthritis Research & Therapy 2005, 7(Suppl 1):S5 (17 February 2005)

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Successful approaches in genetics of musculoskeletal diseases

MA Brown Arthritis Research & Therapy 2005, 7(Suppl 1):S6 (17 February 2005)

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Defining a role for fibroblasts in the persistence of chronic inflammatory joint disease

C Buckley, A Filer, O Haworth, G Parsonage, K Raza, M Salmon Arthritis Research & Therapy 2005, 7(Suppl 1):S14 (17 February 2005)

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Molecular signatures of rheumatoid arthritis characterized by transcriptome and proteome analysis

MO Glocker, J Kekow, H-J Thiesen Arthritis Research & Therapy 2005, 7(Suppl 1):S7 (17 February 2005)

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Regulating apoptosis in fibroblasts

T Pap, A Cinski, A Drynda, A Wille, A Baier, S Gay, I Meinecke Arthritis Research & Therapy 2005, 7(Suppl 1):S15 (17 February 2005)

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Mechanisms of cartilage matrix turnover: synergistic interactions of proinflammatory cytokines with oncostatin M in upregulating matrix metalloproteinases and ADAMTS metalloproteinases

TE Cawston, H Bigg, J Milner, J Catterall, T Morgan, E Barksby, W Hui, A Rowan Arthritis Research & Therapy 2005, 7(Suppl 1):S10 (17 February 2005)

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Collagenases and aggrecanases: understanding the role of non-catalytic domains in cartilage matrix breakdown

H Nagase, R Visse, M Kashiwagi, C Gendron, Y Itoh Arthritis Research & Therapy 2005, 7(Suppl 1):S11 (17 February 2005)

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The effects of inflammatory arthritis on bone remodeling

SR Goldring Arthritis Research & Therapy 2005, 7(Suppl 1):S12 (17 February 2005)

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Genetics and bone disease

SH Ralston Arthritis Research & Therapy 2005, 7(Suppl 1):S13 (17 February 2005)

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Signal transduction in T lymphocytes

D Cantrell Arthritis Research & Therapy 2005, 7(Suppl 1):S17 (17 February 2005)

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Innate immunity and the anti-viral state of rheumatoid synovium

GS Firestein Arthritis Research & Therapy 2005, 7(Suppl 1):S16 (17 February 2005)

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Differential effects of T-cell specific PKC-theta inhibition or selective intra-articular NF-κB inhibition on synovial inflammation in rat adjuvant arthritis

SW Tas, MJ Vervoordeldonk, N Hajji, M May, S Ghosh, PP Tak Arthritis Research & Therapy 2005, 7(Suppl 1):P1 (17 February 2005)

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Positive cytoplasmic indirect immunofluorescence on HEp2 cells of unknown pattern: what to report to rheumatologists

Z Rotar, B Boziè, B Rozman, T Kveder Arthritis Research & Therapy 2005, 7(Suppl 1):P2 (17 February 2005)

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Synovial hypoxia inducible factor-1α expression is inversely related to tissue oxygen levels in vivo in inflammatory arthritis

P Donatien, V Sandhu, D Peston, A Sandisson, PC Taylor Arthritis Research & Therapy 2005, 7(Suppl 1):P3 (17 February 2005)

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Prophylactic administration of abatacept (CTLA4-Ig; BMS-188667) prevents disease induction and bone destruction in a rat model of collagen-induced arthritis

C Kliwinski, D Kukral, J Postelnek, B Krishnan, L Killar, S Nadler, R Townsend Arthritis Research & Therapy 2005, 7(Suppl 1):P4 (17 February 2005)

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The transcription T-bet is required for optimal proinflammatory trafficking of CD4+ T cells

RM Rao, GM Lord, H Choe, AH Lichtman, FW Luscinskas, LH Glimcher Arthritis Research & Therapy 2005, 7(Suppl 1):P5 (17 February 2005)

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Specificity of CD4 T-cell responses to aggrecan in BALB/c and DR1 transgenic mice

K Lowes, AA von Delwig, N McKie, DM Altmann, JA Goodacre, AD Rowan, JH Robinson Arthritis Research & Therapy 2005, 7(Suppl 1):P6 (17 February 2005)

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The role of hypoxia in rheumatoid tendon disease

B Sivakumar, N Kang, P Taylor, EM Paleolog Arthritis Research & Therapy 2005, 7(Suppl 1):P7 (17 February 2005)

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Short-fibre modification facilitates adenovirus-mediated gene delivery in rheumatoid arthritis synoviocytes and synovium: role of RGD and non-RGD binding integrins

M-L Toh, S-S Hong, L Franqueville, L Lindholm, P Boulanger, P Miossec Arthritis Research & Therapy 2005, 7(Suppl 1):P8 (17 February 2005)

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Laminin type 1 augments the transforming growth factor beta-induced expression of matrix metalloproteinase 3 in synovial fibroblasts

M Hoberg, M Rudert, WK Aicher Arthritis Research & Therapy 2005, 7(Suppl 1):P9 (17 February 2005)

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Peptide mimetics of anti-dsDNA idiotypes as a tool for lupus-specific IVIG preparation: specificity and efficacy in the treatment of experimental systemic lupus erythematosus

M Blank, I Nur, R Meidler, L Bar, L Slutzki, Y Shoenfeld Arthritis Research & Therapy 2005, 7(Suppl 1):P10 (17 February 2005)

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Acceleration of apoptotic cells clearance by macrophages upon exposure to serum amyloid P component and its synthetic derivates

L Slutzky, M Blank, G Goddard, M Fridkin, Y Shoenfeld Arthritis Research & Therapy 2005, 7(Suppl 1):P11 (17 February 2005)

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Close association between valvular heart disease and central nervous system manifestations in antiphospholipid syndrome

I Krause, S Lev, A Fraser, M Blank, J Chapman, Y Shoenfeld Arthritis Research & Therapy 2005, 7(Suppl 1):P12 (17 February 2005)

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Elevated titers of anti-ribosomal-P antibodies in systemic lupus erythematosus

G Zandman-Goddard, B Gilburd, S Bardechevski, L Stojanovich, P Langevitz, Y Shoenfeld Arthritis Research & Therapy 2005, 7(Suppl 1):P13 (17 February 2005)

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Human type II collagen is processed in lysosomal compartments of macrophages for presentation of the glycosylated arthritogenic epitope hCII259–273 to CD4 T cells in HLA-DR1 transgenic mice

A von Delwig, DM Altmann, JD Isaacs, R Holmdahl, N McKie, JH Robinson Arthritis Research & Therapy 2005, 7(Suppl 1):P14 (17 February 2005)

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Does the burden of inflammation determined prospectively in patients with early inflammatory arthritis determine the progression of atherosclerosis?

WY Al-Shehhi, S Skehan, E Hefferenan, F Hughes, DJ Veale, B Bresinihan, O Fitzgerald Arthritis Research & Therapy 2005, 7(Suppl 1):P15 (17 February 2005)

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Altered composition of CD97 splice variants in rheumatoid synovial tissue

FA van Gaalen, TCTM van der Pouw Kraan, RGHH Nelissen, TWJ Huizinga, CL Verweij Arthritis Research & Therapy 2005, 7(Suppl 1):P16 (17 February 2005)

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Improvement of T-cell function in rheumatoid arthritis (RA) patients in clinical remission is associated with the recovery of IL-7 expression and depends on a familial history of RA

F Ponchel, AK Brown, SL Field, L Hensor, P Emery, JD Isaacs Arthritis Research & Therapy 2005, 7(Suppl 1):P17 (17 February 2005)

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T-bet expression in rheumatoid arthritis patients with early, disease-modifying anti-rheumatic drug naïve disease is low and correlates with low levels of IL-7 and T-cell dysfunctions

F Ponchel, AK Brown, SL Field, M Quinn, P Conaghan, P Emery, JD Isaacs Arthritis Research & Therapy 2005, 7(Suppl 1):P18 (17 February 2005)

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The signalling signature downstream of the notch receptor in CD4+CD25high regulatory T cells in RA defines anergic cells: insight into resistance to anti-tumour necrosis factor therapies

MH Buch, K Snow, S Field, P Emery, J Isaacs, F Ponchel Arthritis Research & Therapy 2005, 7(Suppl 1):P19 (17 February 2005)

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Citrullinated α enolase, a novel citrullinated autoantigen in rheumatoid arthritis, upregulated by chronic inflammation

A Kinloch, V Tatzer, R Wait, D Peston, S Sacre, P Donatien, D Moyes, P Taylor, PJ Venables Arthritis Research & Therapy 2005, 7(Suppl 1):P20 (17 February 2005)

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Abatacept (CTLA4-Ig) modulates human T-cell proliferation and cytokine production but does not affect lipopolysaccharide-induced tumor necrosis factor alpha production by monocytes

PM Davis, SG Nadler, KA Rouleau, SJ Suchard Arthritis Research & Therapy 2005, 7(Suppl 1):P21 (17 February 2005)

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Intra-articular gene therapy blocking NF-κB using adeno-associated virus type 5 ameliorates adjuvant arthritis in rats

J Adriaansen, SW Tas, N Hajji, A Bakker, MJ Vervoordeldonk, PP Tak Arthritis Research & Therapy 2005, 7(Suppl 1):P22 (17 February 2005)

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Collagenous repeat containing sequence of 26 kDa protein: a novel mesenchymal gene of cartilage and adipose tissue differentiation

IH Tarner, C Büchler, J Schölmerich, E Neumann, S Gay, A Schäffler, U Müller-Ladner Arthritis Research & Therapy 2005, 7(Suppl 1):P23 (17 February 2005)

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Activation of antigen-presenting cells by endogenous retroviral RNA

D Moyes, S Sacre, N Temperton, A Lundberg, B Foxwell, P Venables Arthritis Research & Therapy 2005, 7(Suppl 1):P24 (17 February 2005)

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Anti-tumour necrosis factor alpha treatment in patients affected by rheumatoid arthritis with anti-Ro/SSA antibodies

I Cavazzana, F Franceschini, E Danieli, P Airò, R Cattaneo Arthritis Research & Therapy 2005, 7(Suppl 1):P25 (17 February 2005)

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Ha-Ras/ERK1-2 pathway is responsible for oxygen species generation in scleroderma fibroblasts

S Svegliati, MM Luchetti, P Paroncini, A DiCarlo, F Bevilacqua, N Campelli, E Avvedimento, A Gabrielli Arthritis Research & Therapy 2005, 7(Suppl 1):P26 (17 February 2005)

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Magnetic resonance imaging examinations of the spine in patients with ankylosing spondylitis before and after therapy with the tumor necrosis factor alpha receptor fusion protein etanercept

X Baraliakos, J Davis, W Tsuji, J Braun Arthritis Research & Therapy 2005, 7(Suppl 1):P27 (17 February 2005)

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Two-year follow-up results after re-administration of etanercept in active ankylosing spondylitis

X Baraliakos, J Brandt, J Listing, H Haibel, HM Rudwaleit, J Sieper, J Braun Arthritis Research & Therapy 2005, 7(Suppl 1):P28 (17 February 2005)

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Clinical response to the anti-tumor necrosis factor alpha antibody infliximab in patients with ankylosing spondylitis over 3 years

X Baraliakos, J Brandt, J Listing, J Sieper, J Braun Arthritis Research & Therapy 2005, 7(Suppl 1):P29 (17 February 2005)

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Clinical response to discontinuation of anti-tumor necrosis factor therapy in patients with ankylosing spondylitis after 3 years of continuous treatment with infliximab

X Baraliakos, J Listing, J Brandt, M Rudwaleit, J Sieper, J Braun Arthritis Research & Therapy 2005, 7(Suppl 1):P30 (17 February 2005)

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Radiographic progression in patients with ankylosing spondylitis after 2 years of treatment with the tumor necrosis factor alpha antibody infliximab

X Baraliakos, J Listing, M Rudwaleit, J Brandt, J Sieper, J Braun Arthritis Research & Therapy 2005, 7(Suppl 1):P31 (17 February 2005)

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Oxygen radical production determines chondrocyte death and regulates matrix metalloproteinase-mediated matrix degradation during interferon gamma-accelerated immune complex arthritis

PLEM van Lent, KCAM Nabbe, AEM Holthuysen, JK Kolls, SM Holland, WB van den Berg Arthritis Research & Therapy 2005, 7(Suppl 1):P32 (17 February 2005)

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In systemic sclerosis, levels of tissue kallikrein are related to microvascular changes assayed by videocapillaroscopy and immunohistochemistry

A Del Rosso, AF Milia, LI Manneschi, O Distler, S Guiducci, A Pignone, S Gay, MM Cerinic Arthritis Research & Therapy 2005, 7(Suppl 1):P33 (17 February 2005)

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A complete phylogenetic analysis coupling expression data from EST databases. An example with a family of genes: the peptidyl arginine deiminase genes

N Balandraud, P Gouret, E Danchin, M Blanc, D Zinn, P Pontarotti Arthritis Research & Therapy 2005, 7(Suppl 1):P34 (17 February 2005)

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Expression of innate immune receptors in the immunopathologic lesion of primary Sjogren's syndrome: preliminary results

E Bourazopoulou, EK Kapsogeorgou, JG Routsias, DA Liakos, HM Moutsopoulos, AG Tzioufas Arthritis Research & Therapy 2005, 7(Suppl 1):P35 (17 February 2005)

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The association of different B27 subtypes with the peptide loading complex

JC Goodall, L Ellis, JSH Gaston Arthritis Research & Therapy 2005, 7(Suppl 1):P36 (17 February 2005)

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Functional regulatory immune responses against human cartilage glycoprotein-39 in health versus proinflammatory responses in rheumatoid arthritis

JHM van Bilsen, H van Dongen, LR Lard, EIH van der Voort, DG Elferink, AM Bakker, AMM Miltenburg, TWJ Huizinga, RRP de Vries, REM Toes Arthritis Research & Therapy 2005, 7(Suppl 1):P37 (17 February 2005)

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Differential survival of leucocyte subsets by synovial, bone marrow and skin fibroblasts: site-specific rescue of CD4 T cells versus activation-induced rescue of neutrophils

AD Filer, G Parsonage, AMCT Thomas, SJ Curnow, A Akbar, M Salmon, CD Buckley Arthritis Research & Therapy 2005, 7(Suppl 1):P38 (17 February 2005)

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Regulatory T-cell defect in the arthritis-susceptible DBA/1 mouse

SP Fairchild, M Schenk, R Doffinger, FC Hall Arthritis Research & Therapy 2005, 7(Suppl 1):P39 (17 February 2005)

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Heme oxygenase 1 regulates osteoclastogenesis

J Zwerina, S Hayer, K Redlich, I Radda, O Hoffmann, JS Smolen, G Schett Arthritis Research & Therapy 2005, 7(Suppl 1):P40 (17 February 2005)

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How does tumour necrosis factor uncouple T-cell receptor-induced IL-2 gene expression in murine T cells?

JM Clark, K Aleksiyadis, M Panesar, AP Cope Arthritis Research & Therapy 2005, 7(Suppl 1):P41 (17 February 2005)

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The invasiveness of fibroblast-like synoviocytes is of relevance for the rate of joint destruction in patients with rheumatoid arthritis and is a patient characteristic

TCA Tolboom, AHM van der Helm-van Mil, RGHH Nelissen, FC Breedveld, REM Toes, TWJ Huizinga Arthritis Research & Therapy 2005, 7(Suppl 1):P42 (17 February 2005)

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A role for IL-7 in regulating CD4+CD25high regulatory T cells

CA Lawson, AK Brown, SL Field, C Burgoyne, P Emery, JD Isaacs, F Ponchel Arthritis Research & Therapy 2005, 7(Suppl 1):P43 (17 February 2005)

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Results of the Consensus Finding Study Group on Autoantibodies (March 2003–March 2004)

D Hamann, P Charles, M Renz, HP Seelig, A Wiik, RJT Smeenk Arthritis Research & Therapy 2005, 7(Suppl 1):P44 (17 February 2005)

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Effects of overexpression of PAD4 enzyme in mouse synovium

AJW Zendman, WAM Horstman, AJ Arntz, MB Bennink, ER Vossenaar, WJ van Venrooij, WB van den Berg, FAJ van de Loo, GJM Pruijn Arthritis Research & Therapy 2005, 7(Suppl 1):P45 (17 February 2005)

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Long-term survival after lymphocytotoxic monoclonal antibody therapy for rheumatoid arthritis

JD Isaacs, AM Clarke, BL Hazleman, G Hale, H Waldmann, DPM Symmons Arthritis Research & Therapy 2005, 7(Suppl 1):P46 (17 February 2005)

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The persistence of abnormal T-cell differentiation patterns predicts relapse in rheumatoid arthritis patients with controlled disease

A Brown, F Ponchel, J Isaacs, P Emery Arthritis Research & Therapy 2005, 7(Suppl 1):P47 (17 February 2005)

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The inhibitor of differentiation-2 promotes synovial fibroblast-dependent osteoclastogenesis in rheumatoid arthritis

M Kurowska-Stolarska, J Distler, W Rudnicka, E Neumann, T Pap, R Wenger, A Jungel, BA Michel, U Muller-Ladner, RE Gay, W Maslinski, S Gay, O Distler Arthritis Research & Therapy 2005, 7(Suppl 1):P48 (17 February 2005)

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Abstract withdrawn

Arthritis Research & Therapy 2005, 7(Suppl 1):P49 (17 February 2005)

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Identification of the EGF-TM7 receptor EMR2 and its ligand dermatan sulphate in rheumatoid synovial tissue

EN Kop, MJ Kwakkenbos, GJD Teske, MC Kraan, TJ Smeets, M Stacey, H-H Lin, J Hamann, PP Tak Arthritis Research & Therapy 2005, 7(Suppl 1):P50 (17 February 2005)

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Prevalence and specificity of autoantibodies to defensins in sera of patients with systemic autoimmune diseases

AG Terzoglou, JG Routsias, AG Tzioufas, HM Moutsopoulos Arthritis Research & Therapy 2005, 7(Suppl 1):P51 (17 February 2005)

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Tumor necrosis factor alpha reverses the immunosuppressive properties of mesenchymal stem cells in collagen-induced arthritis

F Djouad, P Plence, C Bony, F Apparailly, C Jorgensen, D Noël Arthritis Research & Therapy 2005, 7(Suppl 1):P52 (17 February 2005)

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Neutralizing IL-17 during re-activation of experimental arthritis prevents joint inflammation and bone erosion by decreasing RANKL and IL-1

MI Koenders, E Lubberts, LAB Joosten, WB van den Berg Arthritis Research & Therapy 2005, 7(Suppl 1):P53 (17 February 2005)

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Functional Toll-like receptor 9 modulates the activity of bone marrow B cells isolated from rheumatoid arthritis patients

W Rudnicka, E Warnawin, M Buler, T Burakowski, M Bik, E Kontny, C Michalak, P Maldyk, W Maslinski Arthritis Research & Therapy 2005, 7(Suppl 1):P54 (17 February 2005)

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BiP induces IL-4-dependent regulatory cells

R Brownlie, LK Myers, VM Corrigall, MD Bodman-Smith, SJ Thompson, GS Panayi Arthritis Research & Therapy 2005, 7(Suppl 1):P55 (17 February 2005)

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High-dose chemotherapy and syngeneic stem cell transplantation in a patient with refractory rheumatoid arthritis: poor response associated with persistence of synovial abnormalities

M van Oosterhout, RJ Verburg, EWN Levarht, D Moolenburgh, I Bajema, RY Barge, WE Fibbe, JM van Laar Arthritis Research & Therapy 2005, 7(Suppl 1):P56 (17 February 2005)

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Expression of IL-18 in muscle tissue of patients with treatment-resistant idiopathic inflammatory myopathies

IE Lundberg, S Barbasso, AK Ulfgren, JA Gracie, IB McInnes Arthritis Research & Therapy 2005, 7(Suppl 1):P57 (17 February 2005)

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Evaluation of chondrocyte micromass culture for the study of cartilage degradation

TG Morgan, X Xu, AD Rowan, TE Cawston Arthritis Research & Therapy 2005, 7(Suppl 1):P58 (17 February 2005)

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A link between complement activation and anti-SSA in immune complex-induced cytokine production in systemic lupus erythematosus

L Mathsson, E Åhlin, H Storfors, J Rönnelid Arthritis Research & Therapy 2005, 7(Suppl 1):P59 (17 February 2005)

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The value of serum type II collagen epitope measurement in assessing early clinical response to treatment with anti-tumour necrosis factor alpha therapy in rheumatoid arthritis

RH Mullan, T Lobanok, C Walsh, L King, O FitzGerald, B Bresnihan, U Fearon, R Poole, DJ Veale Arthritis Research & Therapy 2005, 7(Suppl 1):P60 (17 February 2005)

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Oncostatin M in rheumatoid arthritis: a key cytokine acts synergistically with other proinflammatory cytokines to promote human cartilage loss

U Fearon, R Mullan, R Poole, T Markham, O FitzGerald, B Bresnihan, DJ Veale Arthritis Research & Therapy 2005, 7(Suppl 1):P61 (17 February 2005)

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Methotrexate, through adenosine release, downregulates tumor necrosis factor alpha-induced synovial fibroblast IL-15 expression and proliferation

E Miranda, M Benito, A Balsa, E Martin-Mola Arthritis Research & Therapy 2005, 7(Suppl 1):P62 (17 February 2005)

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Influence of HLA-DR genes on the production of rheumatoid arthritis-specific autoantibodies to citrullinated fibrin

I Auger, M Sebag, C Vincent, S Guis, L Nogueira, B Svensson, A Cantagrel, G Serre, J Roudier Arthritis Research & Therapy 2005, 7(Suppl 1):P63 (17 February 2005)

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Bone marrow as a secondary lymphoid organ: mature T-cell subsets in bone marrow from rheumatoid arthritis and osteoarthritis patients

E Warnawin, T Burakowski, L Jung, P Maldyk, W Maslinski Arthritis Research & Therapy 2005, 7(Suppl 1):P64 (17 February 2005)

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Signaling pathways involved in TRAIL-induced rheumatoid arthritis synovial fibroblast proliferation

J Morel, R Audo, B Combe Arthritis Research & Therapy 2005, 7(Suppl 1):P65 (17 February 2005)

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Local IL-18 gene transfer prevents severe joint destruction in murine collagen-induced arthritis by induction of IL-4 and osteoprotegerin

LAB Joosten, RL Smeets, MI Koenders, MMA Helsen, B Oppers-Walgreen, FAJ van de Loo, E Lubberts, WB van den Berg Arthritis Research & Therapy 2005, 7(Suppl 1):P66 (17 February 2005)

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Gene expression profiling provides a link between high inflammatory synovitis and myofibroblast-like synoviocytes

TCG Timmer, PV Kasperkovitz, LGM van Baarsen, P-P Tak, TWJ Huizinga, TCTM van der Pouw Kraan, CL Verweij Arthritis Research & Therapy 2005, 7(Suppl 1):P67 (17 February 2005)

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Anakinra (Kineret) in psoriasis and psoriatic arthritis: a single-center, open-label, pilot study

A Gibbs, T Markham, C Walsh, B Bresnihan, D Veale, O FitzGerald Arthritis Research & Therapy 2005, 7(Suppl 1):P68 (17 February 2005)

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Engagement of the p55 TNF-R for different periods of time induces qualitatively distinct pathways of tumour necrosis factor signalling and gene expression profiles in murine T cells

P Vagenas, JM Clark, J Testar, M Panesar, I Udalova, T Freeman, P Lyons, AP Cope Arthritis Research & Therapy 2005, 7(Suppl 1):P69 (17 February 2005)

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Expression of Toll-like receptor (TLR) 2, TLR3, TLR4 and TLR7 is increased in rheumatoid arthritis synovium and regulates cytokine production by dendritic cells upon stimulation of TLR specific pathways

MF Roelofs, LAB Joosten, S Abdollahi-Roodsaz, AWT van Lieshout, TRDJ Radstake, WB van den Berg Arthritis Research & Therapy 2005, 7(Suppl 1):P70 (17 February 2005)

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Post-transcriptional regulation of proinflammatory cytokines in arthritis using gene delivery of AU-rich element binding factors

M Khoury, F Apparailly, AR Clark, P Plence, D Noel, C Jorgensen Arthritis Research & Therapy 2005, 7(Suppl 1):P71 (17 February 2005)

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Arthroscopic lavage with methylprednisolone is superior compared with either treatment alone in patients with inflammatory arthritis of the knee: a randomized prospective trial

M van Oosterhout, JK Sont, I Bajema, FC Breedveld, JM van Laar Arthritis Research & Therapy 2005, 7(Suppl 1):P72 (17 February 2005)

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Phenotypic, genotypic and functional characterization of mesenchymal stem cells from synovial membrane compared with bone marrow

F Djouad, D Noël, G Uzé, T Haüpl, P Plence, C Bony, F Apparailly, C Jorgensen Arthritis Research & Therapy 2005, 7(Suppl 1):P73 (17 February 2005)

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Proinflammatory role for AT1 receptors in the rat synovium

AG Price, JC Lockhart, JS McLean, WR Ferrell Arthritis Research & Therapy 2005, 7(Suppl 1):P74 (17 February 2005)

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Proteomic characterisation of cell contact-dependent macrophage activation

MJ Peirce, R Wait, X Wu, S Begum, J Saklatvala, AP Cope Arthritis Research & Therapy 2005, 7(Suppl 1):P75 (17 February 2005)

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Sustained downregulation of the TCRζ chain defines a transition from antigen mode to inflammation mode during terminal T-cell differentiation

Z Zhang, M Panesar, P Amjadi, A Foey, S Owen, F Dazzi, FM Brennan, AP Cope Arthritis Research & Therapy 2005, 7(Suppl 1):P76 (17 February 2005)

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Rheumatoid synovial fibroblasts activate endothelial cells and promote neutrophil recruitment in a flow based multicellular model of the rheumatoid pannus

E Smith, F Lally, A Filer, M Stone, J Shaw, GB Nash, CD Buckley, GE Rainger Arthritis Research & Therapy 2005, 7(Suppl 1):P77 (17 February 2005)

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Impaired early B-cell tolerance in patients with rheumatoid arthritis

J Samuels, Y-S Ng, D Paget, E Meffre Arthritis Research & Therapy 2005, 7(Suppl 1):P78 (17 February 2005)

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Characterization of the IL-12 family of cytokines in human dendritic cells infected with live Chlamydia trachomatis

MK Matyszak, JC Goodall, JSH Gaston Arthritis Research & Therapy 2005, 7(Suppl 1):P79 (17 February 2005)

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NKT cell status and IL-10-dependent therapeutic effect of NKT cell stimulation on collagen-arthritis in DBA/1 mice

N Bessis, A Miellot, A Herbelin, R Zhu, M-C Boissier Arthritis Research & Therapy 2005, 7(Suppl 1):P80 (17 February 2005)

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Distinct patterns of RANKL/osteoprotegerin system modulation through anti-tumour necrosis factor and corticosteroid therapy in rheumatoid arthritis synovium

AI Catrina, D Makrygiannakis, E af Klint, SB Catrina, S Ernestam, L Klareskog, AK Ulfgren Arthritis Research & Therapy 2005, 7(Suppl 1):P81 (17 February 2005)

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IL-1-driven cartilage and bone destruction are dependent on Toll-like receptor (TLR) 4, but not TLR2

S Abdollahi-Roodsaz, LAB Joosten, MF Roelofs, MMA Helsen, B Oppers-Walgreen, CHM Arndtz, TRDJ Radstake, WB van den Berg Arthritis Research & Therapy 2005, 7(Suppl 1):P82 (17 February 2005)

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Differential expression of multidrug resistance-related proteins on monocyte-derived macrophages from rheumatoid arthritis patients

R Oerlemans, BAC Dijkmans, JW van der Heijden, WF Lems, A Reurs, GL Scheffer, RJ Scheper, G Jansen Arthritis Research & Therapy 2005, 7(Suppl 1):P83 (17 February 2005)

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Inhibition of tumour necrosis factor alpha production by activated T cells of rheumatoid arthritis patients by novel anti-folate drugs: an ex vivo pilot study

JW van der Heijden, AH Gerards, R Oerlemans, WF Lems, RJ Scheper, LA Aarden, BAC Dijkmans, G Jansen Arthritis Research & Therapy 2005, 7(Suppl 1):P84 (17 February 2005)

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Marked expression of IL-1 receptors in cell nuclei and muscle fiber membrane in muscle tissue of patients with idiopathic inflammatory myopathies

C Grundtman, S Salomonsson, C Dorph, J Burton, U Andersson, IE Lundberg Arthritis Research & Therapy 2005, 7(Suppl 1):P85 (17 February 2005)

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Interleukin-1 receptor antagonist lentiviral gene transfer to the murine knee joint ameliorates collagen-induced arthritis

FAJ van de Loo, LM Delavallee, OJ Arntz, MB Bennink, LAB Joosten, WB van den Berg Arthritis Research & Therapy 2005, 7(Suppl 1):P86 (17 February 2005)

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Effects of anti-rheumatic treatments on the prostaglandin E2 biosynthetic pathway in synovial tissue and synovial fluid cells from patients with rheumatoid arthritis

M Korotkova, M Westman, KR Gheorghe, E af Klint, C Trollmo, A-K Ulfgren, L Klareskog, P-J Jakobsson Arthritis Research & Therapy 2005, 7(Suppl 1):P87 (17 February 2005)

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Mitogen-activated kinases in psoriatic arthritis: differences in activation and distinct regulation by etanercept therapy

RJU Lories, I Derese, FP Luyten, K de Vlam Arthritis Research & Therapy 2005, 7(Suppl 1):P88 (17 February 2005)

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Identification of a natural soluble form of the IL-18 receptor accessory protein as an immunomodulator in experimental arthritis

RL Smeets, OJ Arntz, MB Bennink, WB van den Berg, FAJ van de Loo Arthritis Research & Therapy 2005, 7(Suppl 1):P89 (17 February 2005)

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Gene expression in chronically activated Th cells

U Niesner, I Albrecht, R Baumgrass, M Janitz, H Lehrach, T Haeupl, J Grun, GR Burmester, A Grutzkau, A Radbruch Arthritis Research & Therapy 2005, 7(Suppl 1):P90 (17 February 2005)

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Intracellular IL-1 receptor antagonist (icIL-1Ra1) does not antagonize growth inhibitory effects of pre-IL-1α in SaOS-2 cells

G Palmer, S Trolliet, D Talabot-Ayer, F Mézin, D Magne, C Gabay Arthritis Research & Therapy 2005, 7(Suppl 1):P91 (17 February 2005)

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Expression of microsomal prostaglandin E synthase-1 in muscle tissue of patients with idiopathic inflammatory myopathies

M Korotkova, S Barbasso, P-J Jakobsson, I Lundberg Arthritis Research & Therapy 2005, 7(Suppl 1):P92 (17 February 2005)

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Quantifying the contribution of the second HLA-DRB1 susceptibility allele to the risk of rheumatoid arthritis: a meta-analysis

IA van Rossum, AH Zwinderman, PP Tak, N de Vries Arthritis Research & Therapy 2005, 7(Suppl 1):P93 (17 February 2005)

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Efficient IL-18 and IL-18BPc adenoviral gene transfer to cultured murine submandibular gland epithelial cells and successful murine retrograde submandibular duct cannulation to modulate IL-18 function in the salivary gland of animal models of Sjogren's syndrome

M Bombardieri, F Barone, G Proctor, FA van de Loo, WB van den Berg, G Valesini, IB McInnes, C Pitzalis Arthritis Research & Therapy 2005, 7(Suppl 1):P94 (17 February 2005)

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Type 1 regulatory T cells in treatment of murine lupus

R Undeutsch, J Humrich, BH Hahn, F Hiepe, G Burmester, A Radbruch, G Riemekasten Arthritis Research & Therapy 2005, 7(Suppl 1):P95 (17 February 2005)

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Hearing improvement in a variant Muckle–Wells syndrome case in response to IL-1 receptor antagonism

M Rynne, C Maclean, MF McDermott, P Emery Arthritis Research & Therapy 2005, 7(Suppl 1):P96 (17 February 2005)

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The cytokine memory of SmD183-119-autoantigen-specific Th cells of systemic lupus erythematosus patients

S Langer, D Langnickel, P Enghard, GR Burmester, F Hiepe, G Riemekasten Arthritis Research & Therapy 2005, 7(Suppl 1):P97 (17 February 2005)

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PTPN22 as a rheumatoid arthritis susceptibility but not severity gene

J Wesoly, VEH Carlton, A Chokkalingam, AHM van der Helm-van Mil, REM Toes, AB Begovic, TWJ Huizinga Arthritis Research & Therapy 2005, 7(Suppl 1):P98 (17 February 2005)

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Tryptase as a PAR-2 activator in joint inflammation

EB Kelso, L Dunning, JC Lockhart, WR Ferrell, R Plevin, CP Sommerhoff Arthritis Research & Therapy 2005, 7(Suppl 1):P99 (17 February 2005)

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HLA DR-DQ haplotypes and genotypes in patients with systemic lupus erythematosus with co-existing Sjogren's syndrome, systemic lupus erythematosus without Sjogren's syndrome and primary Sjogren's syndrome: clinical and laboratory associations

Ch Georgopoulou, E Zintzaras, M Papadimitropoulos, M Spyropoulou, A Stavropoulou, HM Moutsopoulos, MN Manoussakis Arthritis Research & Therapy 2005, 7(Suppl 1):P100 (17 February 2005)

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Specific inhibition of FoxO transcription factors in rheumatoid arthritis synovial tissue

J Ludikhuize, TJM Smeets, M Vinkenoog, ME Sanders, PP Tak, KA Reedquist Arthritis Research & Therapy 2005, 7(Suppl 1):P101 (17 February 2005)

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Quantitative and qualitative analysis of CD4+CD25+ regulatory T cells in systemic lupus erythematosus patients

M Bonelli, JS Smolen, C Scheinecker Arthritis Research & Therapy 2005, 7(Suppl 1):P102 (17 February 2005)

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HSP70/J-protein chaperone machines: expression analysis in granulocytes

A Zgaga-Griesz, A Adolf, S Haak, R Rzepka, I Melchers Arthritis Research & Therapy 2005, 7(Suppl 1):P103 (17 February 2005)

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Genotype-dependent NOS-3 expression and rheumatoid arthritis

M Cattaruzza, I Melchers, M Hecker Arthritis Research & Therapy 2005, 7(Suppl 1):P104 (17 February 2005)

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Anti-high-density lipoprotein antibodies and lipoprotein characteristics in systemic lupus erythematosus-related cardiovascular disease

J Su, A Cederholm, E Hurt-Camejo, E Svenungsson, J Frostegård Arthritis Research & Therapy 2005, 7(Suppl 1):P105 (17 February 2005)

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Discrepancy between jun/fos proto-oncogene mRNA and protein expression in the rheumatoid arthritis synovial membrane

R Huber, B Stuhlmüller, E Kunisch, RW Kinne Arthritis Research & Therapy 2005, 7(Suppl 1):P106 (17 February 2005)

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Distinct biological properties of human mesenchymal stem cells from different sources

C De Bari, F Dell'Accio, J Vanlauwe, C Pitzalis, FP Luyten Arthritis Research & Therapy 2005, 7(Suppl 1):P107 (17 February 2005)

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Regulation of T-cell differentiation by IL-4R α-chain single nucleotide polymorphisms

A Skapenko, I Prots, S Mattyasovszky, CL Yoné, JR Kalden, H Schulze-Koops Arthritis Research & Therapy 2005, 7(Suppl 1):P108 (17 February 2005)

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Role of IL-10 as a susceptibility factor for rheumatoid arthritis and cardiovascular disease

FAS Kurreeman, J De Vries, R Westendorp, AH Van Den Biggelaar, JJM Schonkeren, REM Toes, TWJ Huizinga Arthritis Research & Therapy 2005, 7(Suppl 1):P109 (17 February 2005)

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Regulation of myeloid cell function and MHC class II expression by tumor necrosis factor

RB Mueller, A Skapenko, M Grunke, J Wendler, B Stuhlmuller, JR Kalden, H Schulze-Koops Arthritis Research & Therapy 2005, 7(Suppl 1):P110 (17 February 2005)

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Specific contributions of H-Ras and N-Ras GTPases to T-lymphocyte oxidative stress and integrin-dependent retention in rheumatoid arthritis

PHJ Remans, ME Sanders, PP Tak, KA Reedquist Arthritis Research & Therapy 2005, 7(Suppl 1):P111 (17 February 2005)

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Requirement of IL-17 receptor signaling in resident synoviocytes for development of full blown destructive arthritis

E Lubberts, P Schwarzenberger, W Huang, JR Schurr, JJ Peschon, WB van den Berg, JK Kolls Arthritis Research & Therapy 2005, 7(Suppl 1):P112 (17 February 2005)

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Different molecules at the surface of stimulated T cells induce IL-1beta, tumour necrosis factor and IL-1RA in human monocytes

D Burger, N Molnarfi, L Gruaz, JM Dayer Arthritis Research & Therapy 2005, 7(Suppl 1):P113 (17 February 2005)

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Infliximab treatment does not induce apoptosis in peripheral blood mononuclear cells up to 24 hours after initiation of treatment in rheumatoid arthritis patients

CA Wijbrandts, P Reinders-Blankert, P Klarenbeek, TJM Smeets, MJ Vervoordeldonk, PP Tak Arthritis Research & Therapy 2005, 7(Suppl 1):P114 (17 February 2005)

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Resistance of rheumatoid arthritis synovial fibroblasts to p38 MAP-kinase inhibition of pro-destructive functions mediated by tumor necrosis factor alpha/tumor necrosis factor receptor-1

E Kunisch, B Ukena, R Fuhrmann, A Roth, R Winter, RW Kinne Arthritis Research & Therapy 2005, 7(Suppl 1):P115 (17 February 2005)

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Patterns of gene expression in rheumatoid arthritis synovial tissue: inter-patient variability greater then intra-patient variability in a small study

J Lindberg, E af Klint, A Stark, T Andersson, P Nilsson, L Klareskog, A Ulfgren, J Lundeberg Arthritis Research & Therapy 2005, 7(Suppl 1):P116 (17 February 2005)

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Association of FCGR2A and Fc gamma receptor haplotypes with Spanish polymyalgia rheumatica and giant cell arteritis

AW Morgan, MA Gonzalez-Gay, JI Robinson, SJ Babbage, L Haroon-Rashid, AH Hajeer, WER Ollier, JD Isaacs Arthritis Research & Therapy 2005, 7(Suppl 1):P117 (17 February 2005)

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Noggin haploinsufficiency influences severity of arthritis in different mouse models

M Daans, RJU Lories, I Derese, P Tylzanowski, FP Luyten Arthritis Research & Therapy 2005, 7(Suppl 1):P118 (17 February 2005)

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Toll-like receptor expression in synovial fibroblasts and normal skin fibroblasts and induction of matrix metallo-proteinase expression by various Toll-like receptor ligands

D Kyburz, F Brentano, O Schorr, BA Michel, RE Gay, S Gay Arthritis Research & Therapy 2005, 7(Suppl 1):P119 (17 February 2005)

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Exploring mechanisms of inflammatory hyperalgesia in murine collagen-induced arthritis

JJ Inglis, P Anand, P Facer, G Criado, M Feldmann, RO Williams Arthritis Research & Therapy 2005, 7(Suppl 1):P120 (17 February 2005)

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Association of FCGR3A and FCGR3B haplotypes with rheumatoid arthritis and primary Sjögren's syndrome

S Mackie, JI Robinson, JH Barrett, CA Lawson, S Martin, L Haroon-Rashid, D Cooper, SJ Bowman, CT Pease, PG Conaghan, M Green, M Quinn, JD Isaacs, P Emery, AW Morgan Arthritis Research & Therapy 2005, 7(Suppl 1):P121 (17 February 2005)

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Non-traditional risk and protective factors for cardiovascular disease in systemic lupus erythematosus

A Cederholm, E Svenungsson, D Stengel, G-Z Fei, AG Pockley, E Ninio, J Frostegård Arthritis Research & Therapy 2005, 7(Suppl 1):P122 (17 February 2005)

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Immunomodulatory effect of unpulsed-immature dendritic cells in collagen-induced arthritis

PL Plence, F Apparailly, LM Van Duivenvoorde, LM Charbonnier, REM Toes, C Jorgensen Arthritis Research & Therapy 2005, 7(Suppl 1):P123 (17 February 2005)

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Cytokine expression was assessed during antigen-induced arthritis in the synovial membrane, inguinal lymph node, and spleen using competitive RT-PCR and sandwich ELISA

RW Kinne, D Pohlers, A Siegling, E Buchner, CB Schmidt-Weber, E Palombo-Kinne, F Emmrich, R Bräuer Arthritis Research & Therapy 2005, 7(Suppl 1):P124 (17 February 2005)

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Long-term immune reconstitution after autologous stem-cell transplantation for severe autoimmune diseases

T Alexander, G Massenkeil, E Gromnica-Ihle, GR Burmester, A Radbruch, R Arnold, F Hiepe, A Thiel Arthritis Research & Therapy 2005, 7(Suppl 1):P125 (17 February 2005)

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The effect of B-cell depletion with an anti-CD20 antibody on the immunoglobulin heavy-chain repertoire in a patient with rheumatoid arthritis

A-S Rouzière, C Kneitz, T Dörner, H-P Tony Arthritis Research & Therapy 2005, 7(Suppl 1):P126 (17 February 2005)

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Direct analysis of bone turnover in experimental arthritis

K Polzer, B Tuerk, K Redlich, S Hayer, J Smolen, G Schett Arthritis Research & Therapy 2005, 7(Suppl 1):P127 (17 February 2005)

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Antibodies to ferritin in rheumatoid arthritis are associated with disease severity

D Mewar, DJ Moore, PF Watson, AG Wilson Arthritis Research & Therapy 2005, 7(Suppl 1):P128 (17 February 2005)

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Polymorphism within the telomeric MHC and expression of rheumatoid arthritis candidate genes

D Mewar, I Marinou, JM Timms, R Kilding, AG Wilson Arthritis Research & Therapy 2005, 7(Suppl 1):P129 (17 February 2005)

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Synovial monocytes mediate Rap1-dependent oxidative stress in rheumatoid arthritis T lymphocytes

PH Remans, JM van Laar, ME Sanders, P-P Tak, KA Reedquist Arthritis Research & Therapy 2005, 7(Suppl 1):P130 (17 February 2005)

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Molecular response to cartilage injury

F Dell'Accio, C De Bari, C Pitzalis Arthritis Research & Therapy 2005, 7(Suppl 1):P131 (17 February 2005)

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Binding properties of anti-histone H1 antibodies suggest that nuclei of necrotic cells rather than cells undergoing apoptosis are engulfed in the LE cell phenomenon

E Feierl, JS Smolen, T Karonitsch, GH Stummvoll, H Ekhart, CW Steiner, M Aringer Arthritis Research & Therapy 2005, 7(Suppl 1):P132 (17 February 2005)

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Stat1 and phosphorylated Stat1 are increased in lymphocytes and monocytes of patients with systemic lupus erythematosus

M Aringer, T Karonitsch, CW Steiner, E Feierl, G Steiner, JS Smolen Arthritis Research & Therapy 2005, 7(Suppl 1):P133 (17 February 2005)

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Kinetic and influence of angiogenesis in the course of collagen-induced arthritis

G Clavel, C Valvason, D Lemeiter, M-C Boissier, N Bessis Arthritis Research & Therapy 2005, 7(Suppl 1):P134 (17 February 2005)

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Free radicals regulate glucocorticoid-induced apoptosis in T lymphocytes

PHJ Remans, DM Gerlag, MS Sanders, P Reinders-Blankert, KA Reedquist, PP Tak Arthritis Research & Therapy 2005, 7(Suppl 1):P135 (17 February 2005)

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T-cell receptor-independent induction of interferon gamma expression in human memory Th cells

A Sattler Arthritis Research & Therapy 2005, 7(Suppl 1):P136 (17 February 2005)

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Active immunization (vaccination) against peptides of IL-1β induces self anti-IL-1β antibodies and protects against collagen-induced arthritis

N Bessis, S Bertin-Maghit, C Capini, J Chomilier, S Muller, J-F Zagury, M-C Boissier Arthritis Research & Therapy 2005, 7(Suppl 1):P137 (17 February 2005)

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Autoreactive T cells to histone H1 and core histones in patients with systemic lupus erythematosus

GH Stummvoll, R Fritsch, B Meyer, M Aringer, JS Smolen, G Steiner Arthritis Research & Therapy 2005, 7(Suppl 1):P138 (17 February 2005)

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CCL21 relationship with lymphoid neogenesis and lymphatic vascular system in chronically inflamed synovium

A Manzo, S Bugatti, C Buckley, D Jackson, R Caporali, C Montecucco, C Pitzalis Arthritis Research & Therapy 2005, 7(Suppl 1):P139 (17 February 2005)

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Microparticles from inflammatory cells are strong inducers of matrix metalloproteinases and inflammatory cytokines in synovial fibroblasts

JHW Distler, A Jüngel, LC Huber, A Seemayer, RE Gay, BA Michel, JR Kalden, S Gay, DS Pisetsky, O Distler Arthritis Research & Therapy 2005, 7(Suppl 1):P140 (17 February 2005)

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FcγR-mediated uptake and processing of antigen–immunoglobulin complexes by professional antigen-presenting cells

JMH de Jong, DH Schuurhuis, A Ioan-Facsinay, EIH van der Voort, TJW Huizinga, F Ossendorp, JS Verbeek, REM Toes Arthritis Research & Therapy 2005, 7(Suppl 1):P141 (17 February 2005)

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Treatment of collagen-induced arthritis with cholera toxin-treated dendritic cells

G Criado, JJ Inglis, M Feldmann, RO Williams Arthritis Research & Therapy 2005, 7(Suppl 1):P142 (17 February 2005)

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Decreased binding of annexin V to endothelial cells: a novel mechanism of atherothrombosis in patients with systemic lupus erythematosus

A Cederholm, E Svenungsson, K Jensen-Urstad, C Trollmo, A-K Ulfgren, J Swedenborg, G-Z Fei, J Frostegård Arthritis Research & Therapy 2005, 7(Suppl 1):P143 (17 February 2005)

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TLR-9, but not TLR-2, TLR-3 and TLR-4, is upregulated on peripheral blood mononuclear cells of patients with active systemic lupus erythematosus

ED Papadimitraki, E Koutala, G Bertsias, C Choulaki, H Kritikos, P Sidiropoulos, DT Boumpas Arthritis Research & Therapy 2005, 7(Suppl 1):P144 (17 February 2005)

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Bystander-activated CD4+ memory lymphocytes: a role in the pathology of rheumatoid arthritis?

JT Beech, SH Owen, P Green, P Amjadi, FM Brennan Arthritis Research & Therapy 2005, 7(Suppl 1):P145 (17 February 2005)

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In vivo induction of foxp3 in collagen-induced arthritis treatment with modified dendritic cells

G Falgarone, O Jaen, MC Boissier Arthritis Research & Therapy 2005, 7(Suppl 1):P146 (17 February 2005)

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Investigation of the relationship between the HLADRB1 genotype and the presence of autoantibody to cyclic-citrullinated peptide in patients with rheumatoid arthritis

M Brózik, Z Weiszhár, JRP Gergely, K Merétey, G Poór Arthritis Research & Therapy 2005, 7(Suppl 1):P147 (17 February 2005)

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Endothelial function and activation in women with systemic lupus erythematosus

E Svenungsson, A Cederholm, K Jensen-Urstad, G-Z Fei, J Frostegard Arthritis Research & Therapy 2005, 7(Suppl 1):P148 (17 February 2005)

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Citrullinated peptide-specific CD19+ B cells are present in synovial tissue and peripheral blood of patients with rheumatoid arthritis

S Ruzickova, Z Cimburek, T Moravcova, Z Huzlova, I Vesela, J Niederlova, O Krystufkova, J Vencovsky Arthritis Research & Therapy 2005, 7(Suppl 1):P149 (17 February 2005)

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Identification of genes associated with the presence of ectopic lymphoid structures in rheumatoid arthritis synovial tissues

B Baltus, RE Mebius, M Vondenhoff, TWJ Huizinga, PP Tak, CL Verweij, TCTM van der Pouw Kraan Arthritis Research & Therapy 2005, 7(Suppl 1):P150 (17 February 2005)

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Immunophenotype and functional characteristics of rheumatoid arthritis derived myeloid dendritic cells and plasmacytoid dendritic cells

S Jongbloed, JA Gracie, RD Sturrock, IB McInnes Arthritis Research & Therapy 2005, 7(Suppl 1):P151 (17 February 2005)

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The importance of cell surface RANKL in rheumatoid arthritis

O Krystufkova, J Sinkora, K Jarosova, M Hladikova, J Niederlova, Z Rehakova, D Tegzova, S Ruzickova, J Vencovsky Arthritis Research & Therapy 2005, 7(Suppl 1):P152 (17 February 2005)

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Expression of programmed death (PD)-1 and PD-1 ligands (PD-L1, PD-L2) in peripheral blood mononuclear cells of patients with systemic lupus erythematosus

G Bertsias, A Raptopoulou, E Coutala, M Mamoulaki, H Kritikos, P Sidiropoulos, DT Boumpas Arthritis Research & Therapy 2005, 7(Suppl 1):P153 (17 February 2005)

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Cultured salivary gland epithelial cells from patients with primary Sjögren's syndrome and disease controls are sensitive to signaling via Toll-like receptors 2 and 3: upregulation of intercellular adhesion molecule-1 expression

MP Spachidou, EK Kapsogeorgou, EA Bourazopoulou, HM Moutsopoulos, MN Manoussakis Arthritis Research & Therapy 2005, 7(Suppl 1):P154 (17 February 2005)

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Prevalence of non-rheumatoid arthritis-associated autoantibodies in sera of anti-cyclic citrulline antibody-positive patients

M Brozik, U Böhm, J Csiki, A Polgár, ZS Schmidt, ZS Balogh, M Seszták, J Ortutay, G Bálint, G Hittner, P Bálint, J Korda, L Hodinka, K Meretey Arthritis Research & Therapy 2005, 7(Suppl 1):P155 (17 February 2005)

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Identification of hnRNP-A2 (RA33) as a major B-cell and T-cell autoantigen in pristane–induced arthritis

MH Hoffmann, J Tuncel, K Skriner, M Tohidast-Akrad, G Schett, JS Smolen, R Holmdahl, G Steiner Arthritis Research & Therapy 2005, 7(Suppl 1):P156 (17 February 2005)

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Influence of methotrexate, leflunomide and tumour necrosis factor alpha inhibitors on immune competence in rheumatoid arthritis patients: a long-run monitoring of Epstein–Barr virus load

N Balandraud, S Guis, JB Meynard, I Auger, H Sovran, J Roudier, C Roudier Arthritis Research & Therapy 2005, 7(Suppl 1):P157 (17 February 2005)

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A revised assay for the measurement of T-cell receptor excision circles as a quantitative measure of thymic function in systemic lupus erythematosus

AR Lorenzi, AM Patterson, JD Isaacs Arthritis Research & Therapy 2005, 7(Suppl 1):P158 (17 February 2005)

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Microarray analysis for molecular characterization of disease activity and measuring outcomes of anti-tumour necrosis factor therapy in rheumatoid arthritis

B Stuhlmüller, T Häupl, N Tandon, M Hernandez, C Hultschig, RJ Kuban, J Salfeld, GR Burmester Arthritis Research & Therapy 2005, 7(Suppl 1):P159 (17 February 2005)

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Amelioration of joint inflammation by a PAR-2-specific monoclonal antibody

V King, EB Kelso, JC Lockhart, L Dunning, WR Ferrell, JA Gracie, IB McInnes Arthritis Research & Therapy 2005, 7(Suppl 1):P160 (17 February 2005)

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Real-time quantitative PCR used as a biomarker for synovial gene expression after oral prednisolone therapy in patients with rheumatoid arthritis

DM Gerlag, DL Boyle, P Laud, T Nash, PP Tak, GS Firestein Arthritis Research & Therapy 2005, 7(Suppl 1):P161 (17 February 2005)

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Expression profiling in synovitis: ranking of candidates, diagnostic performance and individualized interpretation

T Häupl, A Grützkau, J Grün, V Krenn, M Rudwaleit, B Stuhlmüller, C Kaps, J Zacher, G Burmester, A Radbruch Arthritis Research & Therapy 2005, 7(Suppl 1):P162 (17 February 2005)

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A role for CD8 cells in cell-contact-mediated inflammation

SE Robertson, A Crilly, JA Gracie, P Life, IB McInnes Arthritis Research & Therapy 2005, 7(Suppl 1):P163 (17 February 2005)

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Complement and Fc receptor cross-talk in the Arthus reaction: the inflammatory cascade confirmed and refined

SR Ali, J Skokowa, N Shushakova, S Konrad, RE Schmidt, JE Gessner Arthritis Research & Therapy 2005, 7(Suppl 1):P164 (17 February 2005)

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Pharmacokinetic study of oral prednisolone compared with intravenous methylprednisolone in patients with vasculitis of rheumatic disease

KA Rouster-Stevens, JA Daru, LM Pachman, B Javonovic, K-L Ngai Arthritis Research & Therapy 2005, 7(Suppl 1):P165 (17 February 2005)

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Characteristics and outcomes in sero-positive late-onset rheumatoid arthritis patients who start a new disease modifying anti-rheumatic drug

VK Ranganath Arthritis Research & Therapy 2005, 7(Suppl 1):P166 (17 February 2005)

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Toll-like receptor 4 polymorphisms and ankylosing spondylitis

R Adam, JA Gracie, RD Sturrock Arthritis Research & Therapy 2005, 7(Suppl 1):P167 (17 February 2005)

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Chemokine decoy receptors in inflammation

G Graham Arthritis Research & Therapy 2005, 7(Suppl 1):S8 (17 February 2005)

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Follow up study of B-lymphocyte depletion in the treatment of patients with systemic lupus erythematosus

MJ Leandro, JCW Edwards, MR Ehrenstein, G Cambridge, DA Isenberg Arthritis Research & Therapy 2005, 7(Suppl 1):S9 (17 February 2005)

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