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Contents of Volume 7 Suppl 1
25th European Workshop for Rheumatology Research
Meeting abstracts
Glasgow, UK. 24-27 February 2005
The organizer would like to thank the following companies who have generously supported the meeting: Abbott Immunology (Main sponsor), Bristol-Myers Squibb, Schering-Plough, Wyeth, AstraZeneca, MSD, Amgen

Poster presentation    
Differential effects of T-cell specific PKC-theta inhibition or selective intra-articular NF-B inhibition on synovial inflammation in rat adjuvant arthritis
SW Tas, MJ Vervoordeldonk, N Hajji, M May, S Ghosh, PP Tak
Arthritis Research & Therapy 2005, 7(Suppl 1):P1 (17 February 2005)
[Full text] [PDF] [PubMed] [Related articles]

Poster presentation    
Positive cytoplasmic indirect immunofluorescence on HEp2 cells of unknown pattern: what to report to rheumatologists
Z Rotar, B Boziè, B Rozman, T Kveder
Arthritis Research & Therapy 2005, 7(Suppl 1):P2 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Synovial hypoxia inducible factor-1 expression is inversely related to tissue oxygen levels in vivo in inflammatory arthritis
P Donatien, V Sandhu, D Peston, A Sandisson, PC Taylor
Arthritis Research & Therapy 2005, 7(Suppl 1):P3 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Prophylactic administration of abatacept (CTLA4-Ig; BMS-188667) prevents disease induction and bone destruction in a rat model of collagen-induced arthritis
C Kliwinski, D Kukral, J Postelnek, B Krishnan, L Killar, S Nadler, R Townsend
Arthritis Research & Therapy 2005, 7(Suppl 1):P4 (17 February 2005)
[Full text] [PDF]

Poster presentation    
The transcription T-bet is required for optimal proinflammatory trafficking of CD4+ T cells
RM Rao, GM Lord, H Choe, AH Lichtman, FW Luscinskas, LH Glimcher
Arthritis Research & Therapy 2005, 7(Suppl 1):P5 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Specificity of CD4 T-cell responses to aggrecan in BALB/c and DR1 transgenic mice
K Lowes, AA von Delwig, N McKie, DM Altmann, JA Goodacre, AD Rowan, JH Robinson
Arthritis Research & Therapy 2005, 7(Suppl 1):P6 (17 February 2005)
[Full text] [PDF]

Poster presentation    
The role of hypoxia in rheumatoid tendon disease
B Sivakumar, N Kang, P Taylor, EM Paleolog
Arthritis Research & Therapy 2005, 7(Suppl 1):P7 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Short-fibre modification facilitates adenovirus-mediated gene delivery in rheumatoid arthritis synoviocytes and synovium: role of RGD and non-RGD binding integrins
M-L Toh, S-S Hong, L Franqueville, L Lindholm, P Boulanger, P Miossec
Arthritis Research & Therapy 2005, 7(Suppl 1):P8 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Laminin type 1 augments the transforming growth factor beta-induced expression of matrix metalloproteinase 3 in synovial fibroblasts
M Hoberg, M Rudert, WK Aicher
Arthritis Research & Therapy 2005, 7(Suppl 1):P9 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Peptide mimetics of anti-dsDNA idiotypes as a tool for lupus-specific IVIG preparation: specificity and efficacy in the treatment of experimental systemic lupus erythematosus
M Blank, I Nur, R Meidler, L Bar, L Slutzki, Y Shoenfeld
Arthritis Research & Therapy 2005, 7(Suppl 1):P10 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Acceleration of apoptotic cells clearance by macrophages upon exposure to serum amyloid P component and its synthetic derivates
L Slutzky, M Blank, G Goddard, M Fridkin, Y Shoenfeld
Arthritis Research & Therapy 2005, 7(Suppl 1):P11 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Close association between valvular heart disease and central nervous system manifestations in antiphospholipid syndrome
I Krause, S Lev, A Fraser, M Blank, J Chapman, Y Shoenfeld
Arthritis Research & Therapy 2005, 7(Suppl 1):P12 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Elevated titers of anti-ribosomal-P antibodies in systemic lupus erythematosus
G Zandman-Goddard, B Gilburd, S Bardechevski, L Stojanovich, P Langevitz, Y Shoenfeld
Arthritis Research & Therapy 2005, 7(Suppl 1):P13 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Human type II collagen is processed in lysosomal compartments of macrophages for presentation of the glycosylated arthritogenic epitope hCII259273 to CD4 T cells in HLA-DR1 transgenic mice
A von Delwig, DM Altmann, JD Isaacs, R Holmdahl, N McKie, JH Robinson
Arthritis Research & Therapy 2005, 7(Suppl 1):P14 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Does the burden of inflammation determined prospectively in patients with early inflammatory arthritis determine the progression of atherosclerosis?
WY Al-Shehhi, S Skehan, E Hefferenan, F Hughes, DJ Veale, B Bresinihan, O Fitzgerald
Arthritis Research & Therapy 2005, 7(Suppl 1):P15 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Altered composition of CD97 splice variants in rheumatoid synovial tissue
FA van Gaalen, TCTM van der Pouw Kraan, RGHH Nelissen, TWJ Huizinga, CL Verweij
Arthritis Research & Therapy 2005, 7(Suppl 1):P16 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Improvement of T-cell function in rheumatoid arthritis (RA) patients in clinical remission is associated with the recovery of IL-7 expression and depends on a familial history of RA
F Ponchel, AK Brown, SL Field, L Hensor, P Emery, JD Isaacs
Arthritis Research & Therapy 2005, 7(Suppl 1):P17 (17 February 2005)
[Full text] [PDF]

Poster presentation    
T-bet expression in rheumatoid arthritis patients with early, disease-modifying anti-rheumatic drug naïve disease is low and correlates with low levels of IL-7 and T-cell dysfunctions
F Ponchel, AK Brown, SL Field, M Quinn, P Conaghan, P Emery, JD Isaacs
Arthritis Research & Therapy 2005, 7(Suppl 1):P18 (17 February 2005)
[Full text] [PDF]

Poster presentation    
The signalling signature downstream of the notch receptor in CD4+CD25high regulatory T cells in RA defines anergic cells: insight into resistance to anti-tumour necrosis factor therapies
MH Buch, K Snow, S Field, P Emery, J Isaacs, F Ponchel
Arthritis Research & Therapy 2005, 7(Suppl 1):P19 (17 February 2005)
[Full text] [PDF]

Poster presentation    
Citrullinated enolase, a novel citrullinated autoantigen in rheumatoid arthritis, upregulated by chronic inflammation
A Kinloch, V Tatzer, R Wait, D Peston, S Sacre, P Donatien, D Moyes, P Taylor, PJ Venables
Arthritis Research & Therapy 2005, 7(Suppl 1):P20 (17 February 2005)
[Full text] [PDF]

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