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Arthritis Research & Therapy publishes selected collections of research articles, conference proceedings, reviews and reports as supplements, which are free to access online. All articles published in supplements are subject to peer review; meeting abstracts undergo review and selection by the conference. Find out more about publishing a supplement with BioMed Central.

Volume 5 Supplement 1

23rd European Workshop for Rheumatology Research

Meeting abstracts

23rd European Workshop for Rheumatology Research

Marseille, France

27 February - 2 March 2003

The organizer would like to thank the following companies who have generously supported the 23rd European Workshop for Rheumatology Research: Abbott, Amgen, Aventis, Merck Sharp and Dohme, Novartis, Pharmacia, Schering-Plough, Wyeth

Meeting abstract   Free

Rheumatoid arthritis – class prediction by autoreactivity profiles

R Bergholz, F Schumann, S Behrens, U Ungethüm, G Valet, WA Schmidt, GR Burmester, JM Engel, WJ van Venrooij, G Steiner, S Bläβ Arthritis Res Ther 2003, 5(Suppl 1):1 (24 February 2003)

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Meeting abstract   Free

Investigation of the reactivity patterns of antifilaggrin antibodies in sera and synovial fluids from patients with rheumatoid arthritis using citrullinated synthetic peptides

M Brózik, J Szakonyi, A Magyar, B Rojkovich, R Tobi, F Hudecz, P Gergely, K Merétey Arthritis Res Ther 2003, 5(Suppl 1):2 (24 February 2003)

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Analysis of the peptidylarginine deiminase V gene in rheumatoid arthritis

L Caponi, E Petit-Teixeira, M Sebbag, F Bongiorni, S Moscato, F Pratesi, J Osorio, M Guerrin-Weber, F Cornelis, G Serre, P Migliorini, European Consortium for Rheumatoid Arthritis Families (ECRAF) Arthritis Res Ther 2003, 5(Suppl 1):3 (24 February 2003)

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Meeting abstract   Free

Subclass distribution of IgG autoantibodies to deiminated fibrinogen in rheumatoid arthritis

S Chapuy-Regaud, L Nogueira, C Clavel, M Sebbag, C Vincent, G Serre Arthritis Res Ther 2003, 5(Suppl 1):4 (24 February 2003)

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Meeting abstract   Free

Peptidylarginine deiminase isoforms expressed in the synovial membrane of rheumatoid arthritis patients

S Chapuy-Regaud, M Sebbag, R Nachat, D Baeten, V Foulquier, M Simon, T Senshu, M Yamada, H Takahara, F De Keyser, G Serre Arthritis Res Ther 2003, 5(Suppl 1):5 (24 February 2003)

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Meeting abstract   Free

Paratope diversity of anti-prothrombin antibodies

S Cucnik, T Kveder, B Bozic Arthritis Res Ther 2003, 5(Suppl 1):6 (24 February 2003)

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Meeting abstract   Free

High-affinity antibodies against β2-glycoprotein I

S Cucnik, T Kveder, A Ambrozic, B Borut Arthritis Res Ther 2003, 5(Suppl 1):7 (24 February 2003)

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Meeting abstract   Free

Anti-Ro/SSA antibodies in rheumatoid arthritis (RA)

F Franceschini, I Cavazzana, F Malacarne, P Airò, R Cattaneo, N Del Papa, A Radice, RA Sinico Arthritis Res Ther 2003, 5(Suppl 1):8 (24 February 2003)

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Presence of anti-RNP-A and anti-RNP-C antibodies is inversely associated with renal symptoms of systemic lupus erythematosus

I Hoffman, I Peene, L Meheus, K De Bosschere, F Hulstaert, TWJ Huizinga, L Cebecauer, D Isenberg, EM Veys, F De Keyser Arthritis Res Ther 2003, 5(Suppl 1):9 (24 February 2003)

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Meeting abstract   Free

Cultured salivary gland epithelial cells release exosomes that contain the Sjögren's-syndrome-associated autoantigenic ribonucleoproteins Ro/SSA and La/SSB

EK Kapsogeorgou, ID Dimitriou, RF Abu-Helu, HM Moutsopoulos, MN Manoussakis Arthritis Res Ther 2003, 5(Suppl 1):10 (24 February 2003)

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Meeting abstract   Free

Low frequency of phosphatidylserine/prothrombin complex antibodies in a cohort of patients with anticardiolipin antibodies and recent thrombosis

H Locht Arthritis Res Ther 2003, 5(Suppl 1):11 (24 February 2003)

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Meeting abstract   Free

Anticardiolipin antibodies of IgG and IgM isotypes reflect different forms of recent thromboembolic events

H Locht, A Wiik Arthritis Res Ther 2003, 5(Suppl 1):12 (24 February 2003)

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Meeting abstract   Free

Autoantibodies in osteoarthritis

J Menard, J Neidel, C Perka, M Sparmann, B Mueller Arthritis Res Ther 2003, 5(Suppl 1):13 (24 February 2003)

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The infectious origin of the antiphospholipid syndrome: induction by passive transfer of anti-β2GPI antibodies induced by common bacteria

M Blank, I Krause, M Fridkin, N Keller, J Kopolovic, I Goldberg, A Tobar, Y Shoenfeld Arthritis Res Ther 2003, 5(Suppl 1):14 (24 February 2003)

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Meeting abstract   Free

FcγRI up-regulation induced by local adenoviral-mediated IFN-γ production aggravates chondrocyte death during immune-complex-mediated arthritis

K Nabbe, PL van Lent, AE Holthuysen, AW Sloetjes, J Kolls, JS Verbeek, WB van den Berg Arthritis Res Ther 2003, 5(Suppl 1):15 (24 February 2003)

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Meeting abstract   Free

The diagnostic significance of autoantibodies in patients with very early rheumatoid arthritis

V Nell, K Machold, W Hueber, G Eberl, H Hiesberger, E Hoefler, J Smolen, G Steiner Arthritis Res Ther 2003, 5(Suppl 1):16 (24 February 2003)

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Meeting abstract   Free

A rapid ELISA based method to determine peptidyl-arginine deiminase activity in biological samples

S Nijenhuis, AJW Zendman, JMH Raats, GJM Pruijn, WJ van Venrooij Arthritis Res Ther 2003, 5(Suppl 1):17 (24 February 2003)

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Meeting abstract   Free

Autoantibodies to deiminated fibrinogen are the most efficient serological criterion for early rheumatoid arthritis diagnosis

L Nogueira, S Chapuy-Regaud, A Constantin, C Clavel, M Sebbag, A Cantagrel, C Vincent, G Serre Arthritis Res Ther 2003, 5(Suppl 1):18 (24 February 2003)

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Meeting abstract   Free

Anti-BIP antibodies in rheumatoid arthritis

GS Panayi, M Bodman-Smith, V Corrigall Arthritis Res Ther 2003, 5(Suppl 1):19 (24 February 2003)

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Antineutrophil cytoplasmic antibodies in synovial fluid from patients with early rheumatoid arthritis

M Puszczewicz, I Zimmermann-Górska, G Bialkowska-Puszczewicz, E Tatarkiewicz Arthritis Res Ther 2003, 5(Suppl 1):20 (24 February 2003)

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Meeting abstract   Free

Biphasic decline/increase for anticitrulline and monophasic decline in anti-type II collagen antibody levels in recently diagnosed RA patients

J Rönnelid, S Rogberg, B Nordmark, J Lampa, I Dahlbom, T Hansson, L Klareskog Arthritis Res Ther 2003, 5(Suppl 1):21 (24 February 2003)

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Meeting abstract   Free

Zinc finger domain of Ro60kD autoantigen is essential for binding of Ro52kD and autoantibodies

JG Routsias, A Makri, C Sakarellos, M Sakarellos-Daitsiotis, A Kosmopoulou, HM Moutsopoulos, AG Tzioufas Arthritis Res Ther 2003, 5(Suppl 1):22 (24 February 2003)

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Differential expression of IgVH mRNAs in human RA synovium detected by single-cell RT-PCR

S Ruzickova, Z Cimburek, J Niederlova, O Horvath, O Krystufkova, T Dörner, J Vencovsky Arthritis Res Ther 2003, 5(Suppl 1):23 (24 February 2003)

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Meeting abstract   Free

Ability of second-generation anti-cyclic citrullinated peptide (CCP) to predict rheumatoid arthritis in patients with early arthritis

A Saraux, JM Berthelot, P Le Goff, P Youinou Arthritis Res Ther 2003, 5(Suppl 1):24 (24 February 2003)

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Meeting abstract   Free

Autoantibodies to hnRNP-A2 in SLE: identification of disease-specific linear epitopes and correlation with disease activity and clinical features

G Schett, F Monneaux, E Hoefler, R Fritsch, M Tohidast-Akrad, J Smolen, S Muller, G Steiner Arthritis Res Ther 2003, 5(Suppl 1):25 (24 February 2003)

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Meeting abstract   Free

Fcγ receptors complement interaction: new aspects in pathogenesis and treatment of vasculititis

RE Schmidt Arthritis Res Ther 2003, 5(Suppl 1):26 (24 February 2003)

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Linear epitopes of two different autoantigens (La/SSB and myelin basic protein) with a high degree of molecular similarity cause different humoral responses

A Terzoglou, JG Routsias, C Sakarellos, M Sakarellos-Daitsiotis, HM Moutsopoulos, AG Tzioufas Arthritis Res Ther 2003, 5(Suppl 1):27 (24 February 2003)

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Meeting abstract   Free

Autoantibodies predict progression to rheumatoid arthritis in undifferentiated arthritis: a prospective cohort study

FA van Gaalen, SP Linn-Rasker, WJ van Venrooij, BA de Jong, FC Breedveld, CL Verweij, REM Toes, TWJ Huizinga Arthritis Res Ther 2003, 5(Suppl 1):28 (24 February 2003)

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Meeting abstract   Free

Autoantibodies to GPI are predominantly present in extra-articular complications of human rheumatoid arthritis

FA van Gaalen, REM Toes, HJ Ditzel, M Schaller, CL Verweij, TWJ Huizinga Arthritis Res Ther 2003, 5(Suppl 1):29 (24 February 2003)

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Citrullination of synovial proteins in murine models of rheumatoid arthritis

E Vossenaar, S Nijenhuis, MM van Helsen, A van der Heijden, WB van den Berg, WJ van Venrooij, L Joosten Arthritis Res Ther 2003, 5(Suppl 1):30 (24 February 2003)

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Fibrinogen-specific T cells in rheumatoid arthritis

E Vossenaar, R Bergholz, F Schumann, GR Burmester, JM Engel, WJ van Venrooij, S Bläβ Arthritis Res Ther 2003, 5(Suppl 1):31 (24 February 2003)

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Meeting abstract   Free

Elevated anti-serum amyloid P component (SAP) antibodies in SLE patients

G Zandman-Goddard, M Blank, P Langevitz, M Pras, Y Levy, T Witte, A Doria, J Rovensky, Y Shoenfeld Arthritis Res Ther 2003, 5(Suppl 1):32 (24 February 2003)

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Meeting abstract   Free

Clinical and immunological effects of anti-TNF therapy in systemic lupus erythematosus (SLE)

M Aringer, G Steiner, WB Graninger, E Höfler, H Hiesberger, C-W Steiner, J Smolen Arthritis Res Ther 2003, 5(Suppl 1):33 (24 February 2003)

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Therapy with soluble TNF receptor (etanercept) induces apoptosis in rheumatoid arthritis (RA) synovium

AI Catrina, C Trollmo, J Lampa, E af Klint, Y Hermansson, L Klareskog, A-K Ulfgren Arthritis Res Ther 2003, 5(Suppl 1):34 (24 February 2003)

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The effect of methotrexate and mycophenolic acid on monokine production in vitro

S de Lathouder, AH Gerards, ER de Groot, LA Aarden Arthritis Res Ther 2003, 5(Suppl 1):35 (24 February 2003)

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Changes in rheumatoid factor reflect the inflammatory response (CRP and ESR) to infliximab treatment

L De Rycke, E Kruithof, N Van Damme, IEA Hoffman, F Van den Bosch, EM Veys, F De Keyser Arthritis Res Ther 2003, 5(Suppl 1):36 (24 February 2003)

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Promoter polymorphisms in the IL-18 gene are associated with rheumatoid arthritis in two independent clinical cohorts

JA Gracie, N Koyama, M Field, F McGarry, A Schobel, IB McInnes, B Moller Arthritis Res Ther 2003, 5(Suppl 1):37 (24 February 2003)

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Combination of the proinflammatory cytokines IL-1, TNF-α and IL-17 leads to enhanced expression and additional recruitment of AP-1 family members, Egr-1 and NF-κB in osteoblast-like cells

C Granet, P Miossec Arthritis Res Ther 2003, 5(Suppl 1):38 (24 February 2003)

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Expression of chemokines and their receptors in synovial tissue of patients with rheumatoid arthritis, osteoarthritis and reactive arthritis

JJ Haringman, TJM Smeets, MC Kraan, PP Tak Arthritis Res Ther 2003, 5(Suppl 1):39 (24 February 2003)

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Osteoprotegerin protects from generalized bone loss in TNF-transgenic mice

S Hayer, K Redlich, J Zwerina, B Bolon, C Dunstan, B Görtz, H Bergmeister, G Kollias, G Steiner, J Smolen, G Schett Arthritis Res Ther 2003, 5(Suppl 1):40 (24 February 2003)

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Meeting abstract   Free

Influence of anti-TNF therapy on monocyte gene expression in rheumatoid arthritis

M Hernandez, L Martinez, O Kiesslich, N Tandon, M Janitz, H Lehrach, F Wagner, T Häupl, GR Burmester, B Stuhlmüller Arthritis Res Ther 2003, 5(Suppl 1):41 (24 February 2003)

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Meeting abstract   Free

Endogenous IL-12p40 is crucial for antigen-induced arthritis and is partly involved in chronic relapsing streptococcal-cell-wall arthritis

M Jacobs, L Joosten, MMA Helsen, E Lubberts, WB van den Berg Arthritis Res Ther 2003, 5(Suppl 1):42 (24 February 2003)

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Meeting abstract   Free

IL-18 directly promotes joint inflammation and induces cartilage destruction through IL-1

L Joosten, E Lubberts, MJM Wagenmans, MMA Helsen, FAJ van de Loo, WB van den Berg Arthritis Res Ther 2003, 5(Suppl 1):43 (24 February 2003)

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Meeting abstract   Free

TNF polymorphisms are associated with the development of joint erosions in psoriatic arthritis

D Kane, J Balding, W Livingstone, L Mynett-Johnson, B Bresnihan, O Smith, O Fitzgerald Arthritis Res Ther 2003, 5(Suppl 1):44 (24 February 2003)

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Meeting abstract   Free

Defect of Th1 immune response of whole blood cells from active patients with rheumatoid arthritis (RA)

M Kawashima, P Miossec Arthritis Res Ther 2003, 5(Suppl 1):45 (24 February 2003)

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Meeting abstract   Free

TNF-α dependency of IL-17-induced joint pathology differs under naive and arthritis conditions in vivo

M Koenders, E Lubberts, L Joosten, B Oppers, L van den Bersselaar, J Kolls, WB van den Berg Arthritis Res Ther 2003, 5(Suppl 1):46 (24 February 2003)

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Meeting abstract   Free

Differential effects of leflunomide and methotrexate on cytokine production in RA

MC Kraan, TJM Smeets, MJ van Loon, FC Breedveld, BAC Dijkmans, PP Tak Arthritis Res Ther 2003, 5(Suppl 1):47 (24 February 2003)

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Meeting abstract   Free

Alveolar macrophages in scleroderma lung disease are activated by TGF-β and IL-4 but not TNF-α

I Luzina, S Atamas, B White Arthritis Res Ther 2003, 5(Suppl 1):48 (24 February 2003)

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Circulating bioactive TNF in rheumatoid arthritis patients treated with infliximab: link to clinical response

H Marotte, P Miossec Arthritis Res Ther 2003, 5(Suppl 1):49 (24 February 2003)

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Meeting abstract   Free

Shared epitope and rheumatoid arthritis severity: association with infliximab treatment in a postmarketing study

H Marotte, P Gaudin, C Alexandre, P Miossec Arthritis Res Ther 2003, 5(Suppl 1):50 (24 February 2003)

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Meeting abstract   Free

High-molecular-weight PEG precipitates from synovial fluid induce more TNF-α than those from serum of RA patients, which is in contrast to patients with other inflammatory arthritides

L Mathsson, N Mohammad Noor, G ElGhazali, O Sjöberg, L Bengtsson, K Nilsson Ekdahl, B Nilsson, J Rönnelid Arthritis Res Ther 2003, 5(Suppl 1):51 (24 February 2003)

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Meeting abstract   Free

A novel therapeutic approach to cytokine modulation in articular inflammation using filarial nematode derived ES-62

IB McInnes, JA Gracie, BP Leung, M Harnett, FY Liew, W Harnett Arthritis Res Ther 2003, 5(Suppl 1):52 (24 February 2003)

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Meeting abstract   Free

Crosstalk between synovial fibroblasts and T lymphocytes in rheumatoid arthritis: effect of methotrexate

E Miranda, A Balsa, M Benito, C de Cózar, D Pascual-Salcedo, E Martín-Mola Arthritis Res Ther 2003, 5(Suppl 1):53 (24 February 2003)

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Meeting abstract   Free

Plasma-cell like morphotype with loss of CD3 expression by Th1 cytokine producing cells

G Page, A Sattler, A Thiel, A Radbruch, P Miossec Arthritis Res Ther 2003, 5(Suppl 1):54 (24 February 2003)

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Effects of leflunomide on interleukin-1 receptor antagonist (IL-1Ra) synthesis in chondrocytes and synovial fibroblasts

G Palmer, D Burger, F Mezin, C Gabay, J-M Dayer, P-A Guerne Arthritis Res Ther 2003, 5(Suppl 1):55 (24 February 2003)

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The Th2 cytokine IL-10 inhibits hyaluronan mRNA accumulation in fibroblast-like synoviocytes

C Pollaschek, KM Stuhlmeier Arthritis Res Ther 2003, 5(Suppl 1):56 (24 February 2003)

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Meeting abstract   Free

Adjustment in anti-TNF therapy after initial response: long-term follow-up in patients with rheumatoid arthritis

P Sidiropoulos, G Kakavouli, DT Boumpas, K Voudouris Arthritis Res Ther 2003, 5(Suppl 1):57 (24 February 2003)

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Infliximab treatment reduces synovial cellularity as early as 48 hours after initiation of treatment, but not by induction of apoptosis

TJM Smeets, MC Kraan, PP Tak Arthritis Res Ther 2003, 5(Suppl 1):58 (24 February 2003)

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Secreted IL-1Ra exerts a protective effect on atherosclerotic lesion development in apolipoprotein-E-deficient mice

F Soussi, BR Kwak, G Pelli, F Mach, C Gabay Arthritis Res Ther 2003, 5(Suppl 1):59 (24 February 2003)

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Meeting abstract   Free

Anti CD4 antibodies directly suppress TNF-α production in human Th1 T-cell clones but not IL-4 production in Th2 clones

S Tschiedel, Y Schwitalle, F Emmrich Arthritis Res Ther 2003, 5(Suppl 1):60 (24 February 2003)

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Meeting abstract   Free

A GATA-3 binding site in the first intron of the interleukin-4 gene defines a critical element for the memory expression of interleukin-4 in Th lymphocytes

L Tykocinski, P Hajkova, T Stamm, O Sözeri, M Löhning, B Friedrich, J Hu-Li, C Pannetier, WE Paul, G Grütz, J Walter, A Radbruch Arthritis Res Ther 2003, 5(Suppl 1):61 (24 February 2003)

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Meeting abstract   Free

A polymorphism in the IL-10 promoter affects autoantibody production and subsequent joint destruction in rheumatoid arthritis

FA van Gaalen, L Lard, J Schonkeren, E Pieterman, G Stoeken, K Vos, R Nelissen, R Westendorp, R Hoeben, FC Breedveld, R Toes, TWJ Huizinga Arthritis Res Ther 2003, 5(Suppl 1):62 (24 February 2003)

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Meeting abstract   Free

Association of single nucleotide polymorphisms within cytokine genes to juvenile idiopathic arthritis in Czech children

J Vavrinec, O Cinek, P Vavrincova, T Slavcev, H Malcova, S Radova Arthritis Res Ther 2003, 5(Suppl 1):63 (24 February 2003)

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Molecular cross-talk between the TRAIL and TGF-β pathways in human lung fibroblasts

VV Yurovsky Arthritis Res Ther 2003, 5(Suppl 1):64 (24 February 2003)

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Isolated and combined inhibition of TNF-, IL-1 and RANKL-pathways in TNF-induced arthritis: effects on synovial inflammation, bone erosion and cartilage destruction

J Zwerina, S Hayer, K Redlich, U Feige, C Dunstan, H Bergmeister, G Kollias, G Steiner, J Smolen, G Schett Arthritis Res Ther 2003, 5(Suppl 1):65 (24 February 2003)

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Interaction between hsp73 and rheumatoid-arthritis-associated HLA-DR alleles

I Auger, J Roudier Arthritis Res Ther 2003, 5(Suppl 1):66 (24 February 2003)

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The presentation of the immunodominant epitope of HC gp-39 in the context of the RA-associated HLA class II molecules is specific for RA synovium

D Baeten, P Steenbakkers, A Boots, EM Veys, F De Keyser Arthritis Res Ther 2003, 5(Suppl 1):67 (24 February 2003)

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Localisation of MHC Class II/HC gp-39 complexes in synovia of rheumatoid arthritis patients using complex-specific monoclonal antibodies

D Baeten, PGA Steenbakkers, E Rovers, EM Veys, AMW Rijnders, J Meijerink, F De Keyser, A Boots Arthritis Res Ther 2003, 5(Suppl 1):68 (24 February 2003)

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Impaired T-cell stimulation by antigen-presenting cells results from defective accessory cell function in HLA-B27 transgenic rat

G Falgarone, C Hacquard-Bouder, A Bosquet, D Monnet, M Breban Arthritis Res Ther 2003, 5(Suppl 1):69 (24 February 2003)

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HLA DRB101 and macrophagic myofasciitis

S Guis, JF Pellissier, F Nicoli, D Reviron, JP Mattei, RK Gherardi, J Pelletier, G Kaplanski, D Figarella-Branger, J Roudier Arthritis Res Ther 2003, 5(Suppl 1):70 (24 February 2003)

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Influence of HLA-DRB1 P4 binding pocket electric charge on rheumatoid arthritis (RA) susceptibility

L Michou, S Tezenas du Montcel, E Petit-Texeira, C Pierlot, I Lemaire, J Osorio, W Frigui, S Lasbleiz, P Quillet, T Bardin, F Clerget, B Prum, F Cornélis, ECRAF Arthritis Res Ther 2003, 5(Suppl 1):71 (24 February 2003)

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CD25+ regulatory cells from HLA-DQ8 transgenic mice are capable of modulating collagen-induced arthritis

ME Morgan, R Sutmuller, HJ Witteveen, RRP de Vries, REM Toes Arthritis Res Ther 2003, 5(Suppl 1):72 (24 February 2003)

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Effect of synovial fluid on adeno-associated virus mediated gene transfer to chondrocytes

V Cottard, G Falgarone, D Lutomski, MC Boissier, N Bessis Arthritis Res Ther 2003, 5(Suppl 1):73 (24 February 2003)

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Tetracycline transcriptional silencer (tTS) tightly controls transgene expression in the skeletal muscle: in vivo intramuscular IL-10 DNA electrotransfer application to arthritis

N Perez, P Plence, V Millet, C Minot, D Noël, O Danos, C Jorgensen, F Apparailly Arthritis Res Ther 2003, 5(Suppl 1):74 (24 February 2003)

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Immunotherapy through injection of immature dendritic cells prevents collagen-induced arthritis

P Plence, R Pfannes, D Noël, F Apparailly, J Sany, C Jorgensen Arthritis Res Ther 2003, 5(Suppl 1):75 (24 February 2003)

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Gene therapy of destructive arthritis in SCID mice

U Sack, A Hirth, A Moessner, M Grapenthin, F Kahlenberg, J Lehmann, U Anderegg, K Ueberla, F Emmrich Arthritis Res Ther 2003, 5(Suppl 1):76 (24 February 2003)

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Treatment with OPG and cellular gene therapy with IL-4 decrease bone resorption-associated inflammation in collagen-induced arthritis

N Saidenberg-Kermanac'h, N Bessis, M-C de Vernejoul, MC Boissier, M Cohen-Solal Arthritis Res Ther 2003, 5(Suppl 1):77 (24 February 2003)

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Gene transfer using artificial chromosomes containing a marker gene in primary cells and rat adjuvant arthritis

MJBM Vervoordeldonk, J Adriaansen, S Vanderbyl, PP Tak Arthritis Res Ther 2003, 5(Suppl 1):78 (24 February 2003)

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The mutation P392L of the sequestosome 1 gene in Paget's disease of bone is frequent in the French population

L Michou, JL Laplanche, P Orcel, P Hilliquin, N Philip, J Roudier, P Quillet, T Bardin, JM Launay, F Cornélis Arthritis Res Ther 2003, 5(Suppl 1):79 (24 February 2003)

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A novel juvenile idiopathic arthritis (JIA) susceptibility gene in HLA class I region marked by microsatellite D6S265

A Smerdel, BA Lie, C Finholt, R Ploski, Ø Førre, DE Undlien, E Thorsby Arthritis Res Ther 2003, 5(Suppl 1):80 (24 February 2003)

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RA-specific expression profiles and new candidate genes

U Ungethüm, T Häupl, D Koczan, H Huber, T v Helversen, P Ruiz, H Witt, M Drungowski, HJ Zacher, C Seyfert, J Neidel, V Krenn, GR Burmester, HJ Thiesen, H Lehrach, S Bläβ Arthritis Res Ther 2003, 5(Suppl 1):81 (24 February 2003)

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Association between ASCA-positivity and carrier of a CARD-15 mutation in patients with Crohn's disease

B van der Cruyssen, F De Keyser, H Peeters, M van den Berghe, D Marichal, I Hoffman, T Van Oostveldt, D Laukens, E Remaut, L Steidler, D Elewaut, C Cuvelier, M de Vos, H Mielants, E Veys Arthritis Res Ther 2003, 5(Suppl 1):82 (24 February 2003)

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Epstein–Barr virus load is higher in rheumatoid arthritis patients than in normal controls

N Pieri-Balandraud, J Baptiste Meynard, I Auger, H Sovran, B Mugnier, D Reviron, J Roudier, C Roudier Arthritis Res Ther 2003, 5(Suppl 1):83 (24 February 2003)

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Fast and sensitive method for the detection of bacteria in synovial fluid by multiplex PCR

R Stuhlmeier, H Broell, KM Stuhlmeier Arthritis Res Ther 2003, 5(Suppl 1):84 (24 February 2003)

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Increased frequency of T cells specific for EBV gp110 in the synovial fluid of patients with rheumatoid arthritis

E Toussirot, D Wendling, J Luka, P Tiberghien, J Roudier Arthritis Res Ther 2003, 5(Suppl 1):85 (24 February 2003)

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Covariation of MHC class I and CD163 positive macrophages in skeletal muscle tissue of polymyositis and dermatomyositis patients after treatment with high-dose intravenous immunoglobulin (IVIg)

S Barbasso, M Dastmalchi, H Alexandersson, IE Lundberg Arthritis Res Ther 2003, 5(Suppl 1):86 (24 February 2003)

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HMGB1, a new proinflammatory molecule of interest in polymyositis and dermatomyositis patients

C Grundtman, A-K Ulfgren, K Borg, U Andersson, H Erlandsson-Harris, IE Lundberg Arthritis Res Ther 2003, 5(Suppl 1):87 (24 February 2003)

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Rhabdomyolysis and myalgia associated with anticholesterolemic treatment as potential signs of susceptibility to malignant hyperthermia

S Guis, D Bendahan, JP Mattei, G Kozak-Ribbens, D Figarella-Branger, S Trefouret, V Bernard, A Lando, J Cozzone Arthritis Res Ther 2003, 5(Suppl 1):88 (24 February 2003)

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The diagnostic value of synovial histopathology in undifferentiated inflammatory arthritis: a prospective study in 154 consecutive patients

D Baeten, E Kruithof, IEA Hoffman, L De Rycke, B Vandooren, EM Veys, F De Keyser Arthritis Res Ther 2003, 5(Suppl 1):89 (24 February 2003)

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Local production of soluble CD163 in the spondyloarthropathic joint

D Baeten, HJ Møller, J Delanghe, EM Veys, SK Moestrup, F De Keyser Arthritis Res Ther 2003, 5(Suppl 1):90 (24 February 2003)

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The use of neural network algorithms for the classification of undifferentiated arthritis by synovial histopathology

D Baeten, B Wyns, I Hoffman, S Sette, L Boullart, F De Keyser Arthritis Res Ther 2003, 5(Suppl 1):91 (24 February 2003)

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CXCL13 and CCL21 play a key role in ectopic lymphoneogenesis in Sjögren's syndrome

F Barone, M Blades, A Manzo, P Morgan, M Montecucco, G Valesini, C Pitzalis Arthritis Res Ther 2003, 5(Suppl 1):92 (24 February 2003)

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Delayed resolution of acute inflammation during zymosan-induced arthritis in leptin-deficient mice

E Bernotiene, G Palmer, D Talabot-Ayer, I Szalay-Quinodoz, C Gabay Arthritis Res Ther 2003, 5(Suppl 1):93 (24 February 2003)

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Chondrocyte number and proteoglycan synthesis in the ageing and osteoarthritic human articular cartilage

K Bobacz, A Soleiman, L Erlacher, J Smolen, WB Graninger Arthritis Res Ther 2003, 5(Suppl 1):94 (24 February 2003)

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Expression and regulation of discoidin domain receptor 1 (DDR1) – a novel receptor for collagen – in normal human renal cells and patients with lupus nephritis

DT Boumpas, T Kuroiwa Arthritis Res Ther 2003, 5(Suppl 1):95 (24 February 2003)

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Human platelets stimulate mesangial cells to produce monocyte chemoattractant protein-1 via the CD40/CD40-ligand pathway and may amplify glomerular injury

DT Boumpas, T Kuroiwa Arthritis Res Ther 2003, 5(Suppl 1):96 (24 February 2003)

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Activation of respiratory burst in polymorphonuclear leukocytes upon contact with stimulated T cells and inhibition by high-density lipoproteins (HDLs)

P Cettour-Rose, J-M Dayer, D Burger, P Roux-Lombard Arthritis Res Ther 2003, 5(Suppl 1):97 (24 February 2003)

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TNF suppresses CD4+ T-CELL responses by attenuating calcium/NFAT-dependent but not ERK-dependent signal transduction pathways

JM Clark, K Aleksiyadis, N Panesar, AP Cope Arthritis Res Ther 2003, 5(Suppl 1):98 (24 February 2003)

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Myeloid-related protein (MRP) 8 and MRP 14 in rheumatoid arthritis and spondyloarthropathy

L De Rycke, D Baeten, D Foell, EM Veys, F De Keyser, J Roth Arthritis Res Ther 2003, 5(Suppl 1):99 (24 February 2003)

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Human chondrocytes, reactive oxygen species production and Nox

L Grange, MJ Stasia, S Vergnaud, JS Lu, C Trocme, P Gaudin, F Morel Arthritis Res Ther 2003, 5(Suppl 1):100 (24 February 2003)

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Predictive markers of disease outcome in synovial tissue: T cells, synovial fibroblasts, and granzyme B cytotoxic cells predict unfavorable outcome in patients with recent-onset rheumatoid arthritis

MC Kraan, JJ Haringman, EC Barg, MD Smith, MJ Ahern, TJM Smeets, FC Breedveld, PP Tak Arthritis Res Ther 2003, 5(Suppl 1):101 (24 February 2003)

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Meeting abstract   Free

OPG and RANKL in serum and synovial fluids of patients with rheumatoid arthritis, osteoarthritis and spondylarthropathy

O Krystufkova, J Niederlova, V Senolt, M Hladikova, S Ruzickova, J Vencovsky Arthritis Res Ther 2003, 5(Suppl 1):102 (24 February 2003)

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Identification of homing peptides specific for human synovium by in vivo phage display selection

L Lee, C Buckley, M Blades, G Panayi, AJ George, C Pitzalis Arthritis Res Ther 2003, 5(Suppl 1):103 (24 February 2003)

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Meeting abstract   Free

Increased susceptibility of osteoarthritis tenocytes to FasL-induced apoptosis is associated with elevated expression of Fas receptor but no alterations in the expression of Sentrin-1/SUMO-1

A Machner, A Baier, A Drynda, S Drynda, G Pap, S Gay, W Neumann, T Pap Arthritis Res Ther 2003, 5(Suppl 1):104 (24 February 2003)

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BCA-1 (CXCL13) and SLC (CCL21) production and lymphoid neogenesis in rheumatoid synovitis

A Manzo, M Carulli, S Paoletti, M Blades, F Barone, G Yanni, R Caporali, C Montecucco, M Uguccioni, C Pitzalis Arthritis Res Ther 2003, 5(Suppl 1):105 (24 February 2003)

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Modulation of VCAM-1 expression with antisense oligonucleotides targeting signalling molecules

J Morel, CC Park, B Combe, K Zhu, AE Koch Arthritis Res Ther 2003, 5(Suppl 1):106 (24 February 2003)

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Inhibition of MMP1, MMP2 and MMP8 by mepacrine

C Pollaschek, KM Stuhlmeier Arthritis Res Ther 2003, 5(Suppl 1):107 (24 February 2003)

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Meeting abstract   Free

The new B-cell-specific exon 1B of the CD5 mRNA favors autoimmunity by preventing the membrane expression of CD5

Y Renaudineau, N Haget, P Le Goff, P Youinou Arthritis Res Ther 2003, 5(Suppl 1):108 (24 February 2003)

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Pro-MMP levels and severity of RA

I Tchetverikov, L Lard, R Hanemaaijer, TWJ Huizinga Arthritis Res Ther 2003, 5(Suppl 1):109 (24 February 2003)

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Fibroblast-like synoviocytes obtained from different joints at different times from one patient show similar invasiveness in vitro

TCA Tolboom, R Nelissen, REM Toes, TWJ Huizinga Arthritis Res Ther 2003, 5(Suppl 1):110 (24 February 2003)

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Serum cartilage oligomer proteins in psoriatic arthritis

I Ujfalussy, M Brózik, J Kelemen, Z Tarján, É Koó Arthritis Res Ther 2003, 5(Suppl 1):111 (24 February 2003)

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The inhibitory receptor FcγRII reduces joint inflammation in immune complex arthritis not only by inhibition of activatory FcγR but also by efficient clearance of immune complexes

PL van Lent, K Nabbe, AB Blom, AE Holthuysen, S Verbeek, WB van den Berg Arthritis Res Ther 2003, 5(Suppl 1):112 (24 February 2003)

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The molecular chaperone BiP (GRP 78) inhibits the differentiation of normal human monocytes into immature dendritic cells

O Vittecoq, V Corrigall, M Bodman-Smith, G Panayi Arthritis Res Ther 2003, 5(Suppl 1):113 (24 February 2003)

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A subset of memory effector T cells in peripheral blood defined by differential expression of the TCR-ζ chain

Z Zhang, N Panesar, AP Cope Arthritis Res Ther 2003, 5(Suppl 1):114 (24 February 2003)

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Combination of cellular imaging and molecular analysis for evaluation of cellular gene therapy of RA

IH Tarner, E Neumann, M Judex, J Schölmerich, S Gay, U Müller-Ladner Arthritis Res Ther 2003, 5(Suppl 1):116 (24 February 2003)

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Meeting abstract   Free

Methotrexate (MTX) inhibition of cytokine production: relationship with clinical outcome and genetic polymorphisms

D Pascual-Salcedo, P Sabina, A Balsa, ME Miranda, J Martin, M Pascual, E Martín Mola Arthritis Res Ther 2003, 5(Suppl 1):115 (24 February 2003)

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