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Review series

The Scientific Basis of Rheumatology: A Decade of Progress

Edited by Peter Lipsky and Ravinder Maini

AR&T 10This special collection of reviews - published to mark Arthritis Research & Therapy’s 10th anniversary - provides an in depth overview of the current status of basic and clinical research in rheumatology, and focuses particularly on developments in the past decade, during which there has been an explosion of new information in the field.

Review    
Toll-like receptors and NOD-like receptors in rheumatic diseases
William J McCormack, Andrew E Parker, Luke A O'Neill
Arthritis Research & Therapy 2009, 11:243 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Outcome measures in inflammatory rheumatic diseases
Jaap Fransen, Piet LCM van Riel
Arthritis Research & Therapy 2009, 11:244 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific understanding of rheumatoid arthritis
Jörg J Goronzy, Cornelia M Weyand
Arthritis Research & Therapy 2009, 11:249 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the clinical understanding of lupus
Mary K Crow
Arthritis Research & Therapy 2009, 11:245 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
B cells in autoimmunity
Thomas Dörner, Annett M Jacobi, Peter E Lipsky
Arthritis Research & Therapy 2009, 11:247 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Lessons from animal models of arthritis over the past decade
Wim B van den Berg
Arthritis Research & Therapy 2009, 11:250 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Progress in osteoporosis and fracture prevention: focus on postmenopausal women
Kenneth G Saag, Piet Geusens
Arthritis Research & Therapy 2009, 11:251 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific and clinical understanding of fibromyalgia
Dan Buskila
Arthritis Research & Therapy 2009, 11:242 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Genetics of rheumatic disease
Alex Clarke, Timothy J Vyse
Arthritis Research & Therapy 2009, 11:248 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Cytokines in chronic rheumatic diseases: is everything lack of homeostatic balance?
Carlo Chizzolini, Jean-Michel Dayer, Pierre Miossec
Arthritis Research & Therapy 2009, 11:246 (14 October 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific understanding of osteoarthritis
Steven B Abramson, Mukundan Attur
Arthritis Research & Therapy 2009, 11:227 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
The value of animal models in predicting genetic susceptibility to complex diseases such as rheumatoid arthritis
Emma Ahlqvist, Malin Hultqvist, Rikard Holmdahl
Arthritis Research & Therapy 2009, 11:226 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Antibody engineering to develop new antirheumatic therapies
John D Isaacs
Arthritis Research & Therapy 2009, 11:225 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
What epidemiology has told us about risk factors and aetiopathogenesis in rheumatic diseases
Jacqueline E Oliver, Alan J Silman
Arthritis Research & Therapy 2009, 11:223 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Cartilage homeostasis in health and rheumatic diseases
Mary B Goldring, Kenneth B Marcu
Arthritis Research & Therapy 2009, 11:224 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases
Sherine E Gabriel, Kaleb Michaud
Arthritis Research & Therapy 2009, 11:229 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific understanding of osteoporosis
Nancy E Lane, Wei Yao
Arthritis Research & Therapy 2009, 11:228 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
The biological and clinical importance of the 'new generation' cytokines in rheumatic diseases
Cem Gabay, Iain B McInnes
Arthritis Research & Therapy 2009, 11:230 (19 May 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Antigen receptor signaling in the rheumatic diseases
Julie Zikherman, Arthur Weiss
Arthritis Research & Therapy 2009, 11:202 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific and clinical understanding of autoinflammatory disorders
Helen J Lachmann, Philip N Hawkins
Arthritis Research & Therapy 2009, 11:212 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Tissue engineering in the rheumatic diseases
Jochen Ringe, Michael Sittinger
Arthritis Research & Therapy 2009, 11:211 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Osteoimmunology in rheumatic diseases
Georg Schett
Arthritis Research & Therapy 2009, 11:210 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Gene therapy of the rheumatic diseases: 1998 to 2008
Christopher H Evans, Steven C Ghivizzani, Paul D Robbins
Arthritis Research & Therapy 2009, 11:209 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific and clinical understanding of the spondyloarthritides
Joachim Sieper
Arthritis Research & Therapy 2009, 11:208 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Transcription profiling of rheumatic diseases
Lisa GM van Baarsen, Carina L Bos, Tineke CTM van der Pouw Kraan, Cornelis L Verweij
Arthritis Research & Therapy 2009, 11:207 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Randomized controlled trial design in rheumatoid arthritis: the past decade
Vibeke Strand, Jeremy Sokolove
Arthritis Research & Therapy 2009, 11:205 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Garden of therapeutic delights: new targets in rheumatic diseases
Jean M Waldburger, Gary S Firestein
Arthritis Research & Therapy 2009, 11:206 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the clinical understanding of rheumatoid arthritis
Josef S Smolen, Daniel Aletaha
Arthritis Research & Therapy 2009, 11:204 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the clinical understanding of osteoarthritis
David T Felson
Arthritis Research & Therapy 2009, 11:203 (30 January 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Cell signalling in macrophages, the principal innate immune effector cells of rheumatoid arthritis
Stefan K Drexler, Philip L Kong, Jeremy Wales, Brian M Foxwell
Arthritis Research & Therapy 2008, 10:216 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Stem cell transplantation for rheumatic autoimmune diseases
Thomas Hügle, Jacob M van Laar
Arthritis Research & Therapy 2008, 10:217 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific understanding of lupus
Stacy P Ardoin, David S Pisetsky
Arthritis Research & Therapy 2008, 10:218 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Epigenetic modifications in rheumatoid arthritis
Simon Strietholt, Britta Maurer, Marvin A Peters, Thomas Pap, Steffen Gay
Arthritis Research & Therapy 2008, 10:219 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Editorial    
Introducing Arthritis Research & Therapy's 10th anniversary issue, 'The Scientific Basis of Rheumatology: A Decade of Progress'
Iain Hrynaszkiewicz, Peter E Lipsky, Ravinder N Maini
Arthritis Research & Therapy 2008, 10:119 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific and clinical understanding of gout
Alexander So
Arthritis Research & Therapy 2008, 10:221 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
What magnetic resonance imaging has told us about the pathogenesis of rheumatoid arthritis the first 50 years
Dennis McGonagle, Ai Lyn Tan
Arthritis Research & Therapy 2008, 10:222 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Mesenchymal stem cells in arthritic diseases
Faye H Chen, Rocky S Tuan
Arthritis Research & Therapy 2008, 10:223 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Vascular involvement in rheumatic diseases: 'vascular rheumatology'
Zoltán Szekanecz, Alisa E Koch
Arthritis Research & Therapy 2008, 10:224 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Review    
Developments in the scientific and clinical understanding of inflammatory myopathies
Ingrid E Lundberg, Cecilia Grundtman
Arthritis Research & Therapy 2008, 10:220 (10 October 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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