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Histone deacetylase inhibitors modulate metalloproteinase gene expression in chondrocytes and block cartilage resorption.
Young DA, Lakey RL, Pennington CJ, Jones D, Kevorkian L, Edwards DR, Cawston TE, Clark IM
Arthritis Res Ther 2005, 7:R503-12
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Research article    
Histone deacetylase inhibitors: A new mode for inhibition of cholesterol metabolism
Chittur SV, Sangster-Guity N, McCormick PJ
BMC Genomics 2008, 9:507 (29 October 2008)
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Review    
Targeting histone deacetylase activity in rheumatoid arthritis and asthma as prototypes of inflammatory disease: should we keep our HATs on?
Grabiec AM, Tak PP, Reedquist KA
Arthritis Research & Therapy 2008, 10:226 (17 October 2008)
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Research article    
Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis
Milner JM, Rowan AD, Cawston TE, Young DA
Arthritis Research & Therapy 2006, 8:R142 (18 August 2006)
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4.


Commentary    
Histone deacetylases a new target for suppression of cartilage degradation?
Mort JS
Arthritis Research & Therapy 2005, 7:155-156 (16 June 2005)
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