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Research articles

All research articles published in Arthritis Research & Therapy are open access which means they are freely and universally available online.

Research article    
Expression and regulation of neurotrophins in the non-degenerate and degenerate human intervertebral disc
Devina Purmessur, Anthony J Freemont, Judith A Hoyland
Arthritis Research & Therapy 2008, 10:R99 (27 August 2008)
[Abstract] [Provisional PDF]

Research article    
Identification of intra-group, inter-individual, and gene-specific variances in mRNA expression profiles in the rheumatoid arthritis synovial membrane
Rene Huber, Christian Hummert, Ulrike Gausmann, Dirk Pohlers, Dirk Koczan, Reinhard Guthke, Raimund W Kinne
Arthritis Research & Therapy 2008, 10:R98 (22 August 2008)
[Abstract] [Provisional PDF]

Research article    
Raised intrathecal levels of APRIL and BAFF in patients with SLE; relationship to neuropsychiatric symptoms
Annie George-Chandy, Estelle Trysberg, Kristina Eriksson
Arthritis Research & Therapy 2008, 10:R97 (22 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Disruption of the thrombospondin-2 gene alters lamellar morphology but does not permit vascularization of the adult mouse lumbar disc
Helen E Gruber, Paul Bornstein, E HELENE Sage, Jane A Ingram, Natalia Zinchenko, H. JAMES Norton, Edward N Hanley Jr
Arthritis Research & Therapy 2008, 10:R96 (21 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Development of a health care utilization data based index for rheumatoid arthritis severity: a preliminary study
Gladys Ting, Sebastian Schneeweiss, Richard Scranton, Jeffrey N Katz, Michael E Weinblatt, Melissa Young, Jerry Avorn, Daniel H Solomon
Arthritis Research & Therapy 2008, 10:R95 (21 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Circulating immune complexes contain citrullinated fibrinogen in rheumatoid arthritis
Xiaoyan Zhao, Nwora L Okeke, Orr Sharpe, Franak M Batliwalla, Annette T Lee, Peggy P Ho, Beren H Tomooka, Peter K Gregersen, William H Robinson
Arthritis Research & Therapy 2008, 10:R94 (18 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
TH-17 cells in rheumatoid arthritis
Shiva Shahrara, QiQuan Huang, Arthur M Mandelin II, Richard M Pope
Arthritis Research & Therapy 2008, 10:R93 (18 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Cia5d regulates a new fibroblast-like synoviocyte invasion-associated gene expression signature
Teresina Laragione, Max Brenner, Wentian Li, Percio S. Gulko
Arthritis Research & Therapy 2008, 10:R92 (15 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Interferon-induced protein IFIT4 is associated with systemic lupus erythematosus and promotes differentiation of monocytes into DC-like cells
Xiangyang Huang, Nan Shen, Chunde Bao, Yueying Gu, Li Wu, Shunle Chen
Arthritis Research & Therapy 2008, 10:R91 (15 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Role of fibroblast growth factor 8 (FGF8) in animal models of osteoarthritis
Masako Uchii, Tadafumi Tamura, Toshio Suda, Masakazu Kakuni, Akira Tanaka, Ichiro Miki
Arthritis Research & Therapy 2008, 10:R90 (12 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix
Hazel Tapp, Ray Deepe, Jane A Ingram, Marshall Kuremsky, Edward N Hanley Jr, Helen E Gruber
Arthritis Research & Therapy 2008, 10:R89 (11 August 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Increased susceptibility to collagen-induced arthritis in female mice carrying congenic Cia40/Pregq2 fragments
Maria Liljander, Åsa Andersson, Rikard Holmdahl, Ragnar Mattsson
Arthritis Research & Therapy 2008, 10:R88 (6 August 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Caveolin-1 expression and stress-induced premature senescence in human intervertebral disc degeneration
Sarah Kathleen Heathfield, Christine Lyn Le Maitre, Judith Alison Hoyland
Arthritis Research & Therapy 2008, 10:R87 (5 August 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Intervertebral disc cells as competent phagocytes in vitro: implications for cell death in disc degeneration
Philip Jones, Lucy Gardner, Janis Menage, Gwyn T Williams, Sally Roberts
Arthritis Research & Therapy 2008, 10:R86 (1 August 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee
Krishanu Sengupta, Krishnaraju V Alluri, Andey Rama Satish, Simanchala Mishra, Trimurtulu Golakoti, Kadainti VS Sarma, Dipak Dey, Siba P Raychaudhuri
Arthritis Research & Therapy 2008, 10:R85 (30 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Local adherent technique for transplanting mesenchymal stem cells as a potential treatment of cartilage defect
Hideyuki Koga, Masayuki Shimaya, Takeshi Muneta, Akimoto Nimura, Toshiyuki Morito, Masaya Hayashi, Shiro Suzuki, Young-Jin Ju, Tomoyuki Mochizuki, Ichiro Sekiya
Arthritis Research & Therapy 2008, 10:R84 (29 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Human palatine tonsil: a new potential tissue source of multipotent mesenchymal progenitor cells
Sasa Janjanin, Farida Djouad, Rabie M Shanti, Dolores Baksh, Kiran Gollapudi, Drago Prgomet, Lars Rackwitz, Arjun S Joshi, Rocky S Tuan
Arthritis Research & Therapy 2008, 10:R83 (28 July 2008)
[Abstract] [Provisional PDF] [PubMed] [Related articles]

Research article    
Brain-derived neurotrophic factor and its receptor in the human and the sand rat intervertebral disc
Helen E Gruber, Jane A Ingram, Gretchen Hoelscher, Natalia Zinchenko, H James Norton, Edward N Hanley Jr
Arthritis Research & Therapy 2008, 10:R82 (17 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
A meta-analysis of the efficacy of fibromyalgia treatment according to level of care
Javier Garcia-Campayo, Jesus Magdalena, Rosa Magallón, Esther Fernández-García, Montserrat Salas, Eva Andrés
Arthritis Research & Therapy 2008, 10:R81 (15 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

Research article    
Lack of association or interactions between the IL-4, IL-4R and IL-13 genes, and rheumatoid arthritis
Ioanna Marinou, Simon H Till, David J Moore, Anthony G Wilson
Arthritis Research & Therapy 2008, 10:R80 (14 July 2008)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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