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Fragmentation of decorin, biglycan, lumican and keratocan is elevated in degenerate human meniscus, knee and hip articular cartilages compared with age-matched macroscopically normal and control tissues.

Melrose J, Fuller ES, Roughley PJ, Smith MM, Kerr B, Hughes CE, Caterson B, Little CB.

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Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease-13: identification of a new biglycan cleavage site.

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Colocalization of the collagen-binding proteoglycans decorin, biglycan, fibromodulin and lumican with different cells in human gingiva.

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Regional assessment of articular cartilage gene expression and small proteoglycan metabolism in an animal model of osteoarthritis.

Young AA, Smith MM, Smith SM, Cake MA, Ghosh P, Read RA, Melrose J, Sonnabend DH, Roughley PJ, Little CB.

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Distinctive localization and function for lumican, fibromodulin and decorin to regulate collagen fibril organization in periodontal tissues.

Matheson S, Larjava H, Häkkinen L.

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Presence of pro-forms of decorin and biglycan in human articular cartilage.

Roughley PJ, White RJ, Mort JS.

Biochem J. 1996 Sep 15;318 ( Pt 3):779-84.

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Aggrecan degradation in human cartilage. Evidence for both matrix metalloproteinase and aggrecanase activity in normal, osteoarthritic, and rheumatoid joints.

Lark MW, Bayne EK, Flanagan J, Harper CF, Hoerrner LA, Hutchinson NI, Singer II, Donatelli SA, Weidner JR, Williams HR, Mumford RA, Lohmander LS.

J Clin Invest. 1997 Jul 1;100(1):93-106.

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McAlinden A, Dudhia J, Bolton MC, Lorenzo P, Heinegård D, Bayliss MT.

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Biglycan knockout mice: new models for musculoskeletal diseases.

Young MF, Bi Y, Ameye L, Chen XD.

Glycoconj J. 2002 May-Jun;19(4-5):257-62. Review.

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Small leucine-rich proteoglycans (SLRPs) in uterine tissues during pregnancy in mice.

San Martin S, Soto-Suazo M, De Oliveira SF, Aplin JD, Abrahamsohn P, Zorn TM.

Reproduction. 2003 Apr;125(4):585-95.

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Biglycan and fibromodulin fragmentation correlates with temporal and spatial annular remodelling in experimentally injured ovine intervertebral discs.

Melrose J, Smith SM, Fuller ES, Young AA, Roughley PJ, Dart A, Little CB.

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Isolation and characterization of small proteoglycans from different zones of the porcine knee meniscus.

Scott PG, Nakano T, Dodd CM.

Biochim Biophys Acta. 1997 Aug 29;1336(2):254-62.

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TGF beta 1 and biglycan, decorin, and fibromodulin metabolism in canine cartilage.

Burton-Wurster N, Liu W, Matthews GL, Lust G, Roughley PJ, Glant TT, Cs-Szabó G.

Osteoarthritis Cartilage. 2003 Mar;11(3):167-76.

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Expression of collagen and aggrecan genes in normal and osteoarthritic murine knee joints.

Chambers MG, Kuffner T, Cowan SK, Cheah KS, Mason RM.

Osteoarthritis Cartilage. 2002 Jan;10(1):51-61.

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Influence of collagen-fibril-based coatings containing decorin and biglycan on osteoblast behavior.

Douglas T, Hempel U, Mietrach C, Viola M, Vigetti D, Heinemann S, Bierbaum S, Scharnweber D, Worch H.

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The development of articular cartilage: II. The spatial and temporal patterns of glycosaminoglycans and small leucine-rich proteoglycans.

Archer CW, Morrison EH, Bayliss MT, Ferguson MW.

J Anat. 1996 Aug;189 ( Pt 1):23-35.

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Small leucine rich repeat proteoglycans (SLRPs) in the human sclera: identification of abundant levels of PRELP.

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Increased degradation and altered tissue distribution of cartilage oligomeric matrix protein in human rheumatoid and osteoarthritic cartilage.

Di Cesare PE, Carlson CS, Stolerman ES, Hauser N, Tulli H, Paulsson M.

J Orthop Res. 1996 Nov;14(6):946-55.

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Expression of biglycan, decorin and fibromodulin in the hypertrophic phase of experimental osteoarthritis.

Dourado GS, Adams ME, Matyas JR, Huang D.

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Apoptotic cell death is not a widespread phenomenon in normal aging and osteoarthritis human articular knee cartilage: a study of proliferation, programmed cell death (apoptosis), and viability of chondrocytes in normal and osteoarthritic human knee cartilage.

Aigner T, Hemmel M, Neureiter D, Gebhard PM, Zeiler G, Kirchner T, McKenna L.

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