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Induction of arthritis by high mobility group box chromosomal protein 1 is independent of tumour necrosis factor signalling.

Pullerits R, Jonsson IM, Kollias G, Tarkowski A.

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High mobility group box chromosomal protein 1, a DNA binding cytokine, induces arthritis.

Pullerits R, Jonsson IM, Verdrengh M, Bokarewa M, Andersson U, Erlandsson-Harris H, Tarkowski A.

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Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion.

Woolley DE, Tetlow LC.

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[High mobility group box-1 protein activates endothelial cells to produce cytokines and has synergistic effect with lipopolysaccharide in inducing interleukin-6 release]

Liu JH, Li ZJ, Tang J, Liu YW, Zhao L, Deng P, Jiang Y.

Zhonghua Yi Xue Za Zhi. 2006 May 9;86(17):1191-5. Chinese.

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Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.

Joosten LA, Lubberts E, Helsen MM, Saxne T, Coenen-de Roo CJ, Heinegård D, van den Berg WB.

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HMGB1 is a potent trigger of arthritis.

Andersson U, Erlandsson-Harris H.

J Intern Med. 2004 Mar;255(3):344-50. Review.

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HMGB1 modulates inflammatory responses in LPS-activated macrophages.

El Gazzar M.

Inflamm Res. 2007 Apr;56(4):162-7.

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RAGE is the major receptor for the proinflammatory activity of HMGB1 in rodent macrophages.

Kokkola R, Andersson A, Mullins G, Ostberg T, Treutiger CJ, Arnold B, Nawroth P, Andersson U, Harris RA, Harris HE.

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[The plasmic translocation and release of high mobility group box chromosomal protein 1 in peripheral blood monocytes of patients with rheumatoid arthritis and the effect of thalidomide]

Zuo XX, Gong YH, Zhou YO, Luo H, Xiao XZ.

Zhonghua Nei Ke Za Zhi. 2008 May;47(5):374-7. Chinese.

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IFN-gamma induces high mobility group box 1 protein release partly through a TNF-dependent mechanism.

Rendon-Mitchell B, Ochani M, Li J, Han J, Wang H, Yang H, Susarla S, Czura C, Mitchell RA, Chen G, Sama AE, Tracey KJ, Wang H.

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High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine.

Taniguchi N, Kawahara K, Yone K, Hashiguchi T, Yamakuchi M, Goto M, Inoue K, Yamada S, Ijiri K, Matsunaga S, Nakajima T, Komiya S, Maruyama I.

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Pharmacological blockade of CCR1 ameliorates murine arthritis and alters cytokine networks in vivo.

Amat M, Benjamim CF, Williams LM, Prats N, Terricabras E, Beleta J, Kunkel SL, Godessart N.

Br J Pharmacol. 2006 Nov;149(6):666-75. Epub 2006 Oct 3.

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HMGB1 as a DNA-binding cytokine.

Andersson U, Erlandsson-Harris H, Yang H, Tracey KJ.

J Leukoc Biol. 2002 Dec;72(6):1084-91. Review.

PMID: 12488489 [PubMed - indexed for MEDLINE]

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HMGB1 develops enhanced proinflammatory activity by binding to cytokines.

Sha Y, Zmijewski J, Xu Z, Abraham E.

J Immunol. 2008 Feb 15;180(4):2531-7.

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Expression of Toll-like receptor 2 on CD16+ blood monocytes and synovial tissue macrophages in rheumatoid arthritis.

Iwahashi M, Yamamura M, Aita T, Okamoto A, Ueno A, Ogawa N, Akashi S, Miyake K, Godowski PJ, Makino H.

Arthritis Rheum. 2004 May;50(5):1457-67.

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Intraarticular glucocorticoid treatment reduces inflammation in synovial cell infiltrations more efficiently than in synovial blood vessels.

af Klint E, Grundtman C, Engström M, Catrina AI, Makrygiannakis D, Klareskog L, Andersson U, Ulfgren AK.

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Influence of therapy with chimeric monoclonal tumour necrosis factor-alpha antibodies on intracellular cytokine profiles of T lymphocytes and monocytes in rheumatoid arthritis patients.

Schuerwegh AJ, Van Offel JF, Stevens WJ, Bridts CH, De Clerck LS.

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The major role of macrophages and their product tumor necrosis factor alpha in the induction of arthritis triggered by bacterial DNA containing CpG motifs.

Deng GM, Verdrengh M, Liu ZQ, Tarkowski A.

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Endogenous interleukin-6, but not tumor necrosis factor alpha, contributes to the development of toll-like receptor 4/myeloid differentiation factor 88-mediated acute arthritis in mice.

Kyo F, Futani H, Matsui K, Terada M, Adachi K, Nagata K, Sano H, Tateishi H, Tsutsui H, Nakanishi K.

Arthritis Rheum. 2005 Aug;52(8):2530-40.

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Soluble receptor for advanced glycation end products triggers a proinflammatory cytokine cascade via beta2 integrin Mac-1.

Pullerits R, Brisslert M, Jonsson IM, Tarkowski A.

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