Proteinases in the joint: clinical relevance of proteinases in joint destruction.

Rengel Y, Ospelt C, Gay S.

Arthritis Res Ther. 2007;9(5):221. Review.

PMID: 18001502 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

The clinical potential of matrix metalloproteinase inhibitors in the rheumatic disorders.

Elliott S, Cawston T.

Drugs Aging. 2001;18(2):87-99. Review.

PMID: 11346130 [PubMed - indexed for MEDLINE]

Related Articles

Understanding the role of tissue degrading enzymes and their inhibitors in development and disease.

Cawston TE, Wilson AJ.

Best Pract Res Clin Rheumatol. 2006 Oct;20(5):983-1002. Review.

PMID: 16980219 [PubMed - indexed for MEDLINE]

Related Articles

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids from patients with rheumatoid arthritis or osteoarthritis.

Yoshihara Y, Nakamura H, Obata K, Yamada H, Hayakawa T, Fujikawa K, Okada Y.

Ann Rheum Dis. 2000 Jun;59(6):455-61.

PMID: 10834863 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Matrix metalloproteinases: role in arthritis.

Burrage PS, Mix KS, Brinckerhoff CE.

Front Biosci. 2006 Jan 1;11:529-43. Review.

PMID: 16146751 [PubMed - indexed for MEDLINE]

Related Articles

Matrix metalloproteinase knockout studies and the potential use of matrix metalloproteinase inhibitors in the rheumatic diseases.

Milner JM, Cawston TE.

Curr Drug Targets Inflamm Allergy. 2005 Jun;4(3):363-75. Review.

PMID: 16101546 [PubMed - indexed for MEDLINE]

Related Articles

Reappraising metalloproteinases in rheumatoid arthritis and osteoarthritis: destruction or repair?

Murphy G, Nagase H.

Nat Clin Pract Rheumatol. 2008 Mar;4(3):128-35. Review.

PMID: 18253109 [PubMed - indexed for MEDLINE]

Related Articles

Metalloproteinase inhibitors and the prevention of connective tissue breakdown.

Cawston TE.

Pharmacol Ther. 1996;70(3):163-82. Review.

PMID: 8888065 [PubMed - indexed for MEDLINE]

Related Articles

Protection against cartilage and bone destruction by systemic interleukin-4 treatment in established murine type II collagen-induced arthritis.

Joosten LA, Lubberts E, Helsen MM, Saxne T, Coenen-de Roo CJ, Heinegård D, van den Berg WB.

Arthritis Res. 1999;1(1):81-91. Epub 1999 Oct 26.

PMID: 11056663 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Matrix metalloproteinases and TIMPs: properties and implications for the rheumatic diseases.

Cawston T.

Mol Med Today. 1998 Mar;4(3):130-7. Review.

PMID: 9575496 [PubMed - indexed for MEDLINE]

Related Articles

Clinical implications of matrix metalloproteinases.

Mandal M, Mandal A, Das S, Chakraborti T, Sajal C.

Mol Cell Biochem. 2003 Oct;252(1-2):305-29. Review.

PMID: 14577606 [PubMed - indexed for MEDLINE]

Related Articles

Local overexpression of adeno-viral IL-4 protects cartilage from metallo proteinase-induced destruction during immune complex-mediated arthritis by preventing activation of pro-MMPs.

van Lent PL, Holthuysen AE, Slöetjes A, Lubberts E, van den Berg WB.

Osteoarthritis Cartilage. 2002 Mar;10(3):234-43.

PMID: 11869085 [PubMed - indexed for MEDLINE]

Related Articles

Local IL-13 gene transfer prior to immune-complex arthritis inhibits chondrocyte death and matrix-metalloproteinase-mediated cartilage matrix degradation despite enhanced joint inflammation.

Nabbe KC, van Lent PL, Holthuysen AE, Sloëtjes AW, Koch AE, Radstake TR, van den Berg WB.

Arthritis Res Ther. 2005;7(2):R392-401. Epub 2005 Jan 26.

PMID: 15743487 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

The effects of 1 alpha,25-dihydroxyvitamin D(3) on matrix metalloproteinase and prostaglandin E(2) production by cells of the rheumatoid lesion.

Tetlow LC, Woolley DE.

Arthritis Res. 1999;1(1):63-70. Epub 1999 Oct 14.

PMID: 11056661 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC

Basic calcium phosphate crystals: pathways to joint degeneration.

Molloy ES, McCarthy GM.

Curr Opin Rheumatol. 2006 Mar;18(2):187-92. Review.

PMID: 16462527 [PubMed - indexed for MEDLINE]

Related Articles

Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage.

Abramson SB, Amin A.

Rheumatology (Oxford). 2002 Sep;41(9):972-80. Review.

PMID: 12209029 [PubMed - indexed for MEDLINE]

Related Articles

Matrix metalloproteinases and their inhibitors in bone: an overview of regulation and functions.

Varghese S.

Front Biosci. 2006 Sep 1;11:2949-66. Review.

PMID: 16720367 [PubMed - indexed for MEDLINE]

Related Articles

Proteinases and inhibitors.

Cawston TE.

Br Med Bull. 1995 Apr;51(2):385-401. Review.

PMID: 7552071 [PubMed - indexed for MEDLINE]

Related Articles

Cathepsin K deficiency partially inhibits, but does not prevent, bone destruction in human tumor necrosis factor-transgenic mice.

Schurigt U, Hummel KM, Petrow PK, Gajda M, Stöckigt R, Middel P, Zwerina J, Janik T, Bernhardt R, Schüler S, Scharnweber D, Beckmann F, Saftig P, Kollias G, Schett G, Wiederanders B, Bräuer R.

Arthritis Rheum. 2008 Feb;58(2):422-34.

PMID: 18240253 [PubMed - indexed for MEDLINE]

Related Articles

Adenoviral gene transfer of interleukin-1 in combination with oncostatin M induces significant joint damage in a murine model.

Rowan AD, Hui W, Cawston TE, Richards CD.

Am J Pathol. 2003 Jun;162(6):1975-84.

PMID: 12759253 [PubMed - indexed for MEDLINE]

Related Articles Free article in PMC