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Cells of the synovium in rheumatoid arthritis. Dendritic cells.

Lutzky V, Hannawi S, Thomas R.

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Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1.

Grall F, Gu X, Tan L, Cho JY, Inan MS, Pettit AR, Thamrongsak U, Choy BK, Manning C, Akbarali Y, Zerbini L, Rudders S, Goldring SR, Gravallese EM, Oettgen P, Goldring MB, Libermann TA.

Arthritis Rheum. 2003 May;48(5):1249-60.

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Pathogenesis of rheumatoid arthritis.

Weyand CM, Goronzy JJ.

Med Clin North Am. 1997 Jan;81(1):29-55.

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Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: involvement of phosphatidylinositol 3-kinase and nuclear factor kappaB pathways in tumor necrosis factor alpha production in rheumatoid arthritis.

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Interleukin (IL)-23 p19 expression induced by IL-1beta in human fibroblast-like synoviocytes with rheumatoid arthritis via active nuclear factor-kappaB and AP-1 dependent pathway.

Liu FL, Chen CH, Chu SJ, Chen JH, Lai JH, Sytwu HK, Chang DM.

Rheumatology (Oxford). 2007 Aug;46(8):1266-73. Epub 2007 Jun 14.

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Amplification of the synovial inflammatory response through activation of mitogen-activated protein kinases and nuclear factor kappaB using ligation of CD40 on CD14+ synovial cells from patients with rheumatoid arthritis.

Harigai M, Hara M, Kawamoto M, Kawaguchi Y, Sugiura T, Tanaka M, Nakagawa M, Ichida H, Takagi K, Higami-Ohsako S, Shimada K, Kamatani N.

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Involvement of receptor activator of NFkappaB ligand and tumor necrosis factor-alpha in bone destruction in rheumatoid arthritis.

Romas E, Gillespie MT, Martin TJ.

Bone. 2002 Feb;30(2):340-6. Review.

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Local treatment with the selective IkappaB kinase beta inhibitor NEMO-binding domain peptide ameliorates synovial inflammation.

Tas SW, Vervoordeldonk MJ, Hajji N, May MJ, Ghosh S, Tak PP.

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Anti-malarial agent artesunate inhibits TNF-alpha-induced production of proinflammatory cytokines via inhibition of NF-kappaB and PI3 kinase/Akt signal pathway in human rheumatoid arthritis fibroblast-like synoviocytes.

Xu H, He Y, Yang X, Liang L, Zhan Z, Ye Y, Yang X, Lian F, Sun L.

Rheumatology (Oxford). 2007 Jun;46(6):920-6. Epub 2007 Feb 21.

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[The immunologic homunculus in rheumatoid arthritis. A new viewpoint of immunopathogenesis in rheumatoid arthritis and therapeutic consequences]

Bläss S, Engel JM, Burmester GR.

Z Rheumatol. 2001 Feb;60(1):1-16. Review. German.

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Rheumatoid arthritis synovium contains plasmacytoid dendritic cells.

Cavanagh LL, Boyce A, Smith L, Padmanabha J, Filgueira L, Pietschmann P, Thomas R.

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Monocyte chemoattractant protein-1 (MCP-1) in inflammatory joint diseases and its involvement in the cytokine network of rheumatoid synovium.

Harigai M, Hara M, Yoshimura T, Leonard EJ, Inoue K, Kashiwazaki S.

Clin Immunol Immunopathol. 1993 Oct;69(1):83-91.

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Interleukin-18 enhances monocyte tumor necrosis factor alpha and interleukin-1beta production induced by direct contact with T lymphocytes: implications in rheumatoid arthritis.

Dai SM, Matsuno H, Nakamura H, Nishioka K, Yudoh K.

Arthritis Rheum. 2004 Feb;50(2):432-43.

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Mast cell activation and its relation to proinflammatory cytokine production in the rheumatoid lesion.

Woolley DE, Tetlow LC.

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[Rheumatoid arthritis: new developments in the pathogenesis with special reference to synovial fibroblasts]

Seemayer CA, Distler O, Kuchen S, Müller-Ladner U, Michel BA, Neidhart M, Gay RE, Gay S.

Z Rheumatol. 2001 Oct;60(5):309-18. Review. German.

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Increased AP-1 and NF-kappaB activation and recruitment with the combination of the proinflammatory cytokines IL-1beta, tumor necrosis factor alpha and IL-17 in rheumatoid synoviocytes.

Granet C, Maslinski W, Miossec P.

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Activation of nuclear orphan receptor NURR1 transcription by NF-kappa B and cyclic adenosine 5'-monophosphate response element-binding protein in rheumatoid arthritis synovial tissue.

McEvoy AN, Murphy EA, Ponnio T, Conneely OM, Bresnihan B, FitzGerald O, Murphy EP.

J Immunol. 2002 Mar 15;168(6):2979-87.

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Resistance of rheumatoid synovial dendritic cells to the immunosuppressive effects of IL-10.

MacDonald KP, Pettit AR, Quinn C, Thomas GJ, Thomas R.

J Immunol. 1999 Nov 15;163(10):5599-607.

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Induction of cytokines and ICAM-1 by proinflammatory cytokines in primary rheumatoid synovial fibroblasts and inhibition by N-acetyl-L-cysteine and aspirin.

Sakurada S, Kato T, Okamoto T.

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RhoA-mediated, tumor necrosis factor alpha-induced activation of NF-kappaB in rheumatoid synoviocytes: inhibitory effect of simvastatin.

Xu H, Liu P, Liang L, Danesh FR, Yang X, Ye Y, Zhan Z, Yu X, Peng H, Sun L.

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