Your browser version may not work well with NCBI's Web applications. More information here...

Recent Activity

Items 1 - 20 of 144
of 8Next
1:

Gene therapy with an improved doxycycline-regulated plasmid encoding a tumour necrosis factor-alpha inhibitor in experimental arthritis.

Gould D, Yousaf N, Fatah R, Subang MC, Chernajovsky Y.

Arthritis Res Ther. 2007;9(1):R7.

PMID: 17254348 [PubMed - indexed for MEDLINE]

2:

Inhibition of established collagen-induced arthritis with a tumour necrosis factor-alpha inhibitor expressed from a self-contained doxycycline regulated plasmid.

Gould DJ, Bright C, Chernajovsky Y.

Arthritis Res Ther. 2004;6(2):R103-13. Epub 2003 Dec 22.

PMID: 15059273 [PubMed - indexed for MEDLINE]

3:

A novel doxycycline inducible autoregulatory plasmid which displays "on"/"off" regulation suited to gene therapy applications.

Gould DJ, Berenstein M, Dreja H, Ledda F, Podhajcer OL, Chernajovsky Y.

Gene Ther. 2000 Dec;7(24):2061-70.

PMID: 11223986 [PubMed - indexed for MEDLINE]

4:

Gene therapy of collagen-induced arthritis by electrotransfer of human tumor necrosis factor-alpha soluble receptor I variants.

Bloquel C, Bessis N, Boissier MC, Scherman D, Bigey P.

Hum Gene Ther. 2004 Feb;15(2):189-201.

PMID: 14975191 [PubMed - indexed for MEDLINE]

5:

Electro-gene therapy of collagen-induced arthritis by using an expression plasmid for the soluble p75 tumor necrosis factor receptor-Fc fusion protein.

Kim JM, Ho SH, Hahn W, Jeong JG, Park EJ, Lee HJ, Yu SS, Lee CS, Lee YW, Kim S.

Gene Ther. 2003 Aug;10(15):1216-24.

PMID: 12858186 [PubMed - indexed for MEDLINE]

6:

Tetracycline transcriptional silencer tightly controls transgene expression after in vivo intramuscular electrotransfer: application to interleukin 10 therapy in experimental arthritis.

Perez N, Plence P, Millet V, Greuet D, Minot C, Noel D, Danos O, Jorgensen C, Apparailly F.

Hum Gene Ther. 2002 Dec 10;13(18):2161-72.

PMID: 12542847 [PubMed - indexed for MEDLINE]

7:

Inflammation-inducible anti-TNF gene expression mediated by intra-articular injection of serotype 5 adeno-associated virus reduces arthritis.

Khoury M, Adriaansen J, Vervoordeldonk MJ, Gould D, Chernajovsky Y, Bigey P, Bloquel C, Scherman D, Tak PP, Jorgensen C, Apparailly F.

J Gene Med. 2007 Jul;9(7):596-604.

PMID: 17514770 [PubMed - indexed for MEDLINE]

8:

Doxycycline-regulated lentiviral vector system with a novel reverse transactivator rtTA2S-M2 shows a tight control of gene expression in vitro and in vivo.

Koponen JK, Kankkonen H, Kannasto J, Wirth T, Hillen W, Bujard H, Ylä-Herttuala S.

Gene Ther. 2003 Mar;10(6):459-66.

PMID: 12621450 [PubMed - indexed for MEDLINE]

9:

Intra-articular electrotransfer of plasmid encoding soluble TNF receptor variants in normal and arthritic mice.

Bloquel C, Denys A, Boissier MC, Apparailly F, Bigey P, Scherman D, Bessis N.

J Gene Med. 2007 Nov;9(11):986-93.

PMID: 17912759 [PubMed - indexed for MEDLINE]

10:

Effects of viral interleukin 10 introduced by in vivo electroporation on arthrogen-induced arthritis in mice.

Kuroda T, Maruyama H, Shimotori M, Higuchi N, Kameda S, Tahara H, Miyazaki J, Gejyo F.

J Rheumatol. 2006 Mar;33(3):455-62.

PMID: 16511914 [PubMed - indexed for MEDLINE]

11:

Intraarticular gene transfer of TNFR:Fc suppresses experimental arthritis with reduced systemic distribution of the gene product.

Chan JM, Villarreal G, Jin WW, Stepan T, Burstein H, Wahl SM.

Mol Ther. 2002 Dec;6(6):727-36.

PMID: 12498769 [PubMed - indexed for MEDLINE]

12:

Immune modulation of collagen-induced arthritis by intranasal cytokine gene delivery: a model for the therapy of rheumatoid arthritis.

Woods AM, Thompson SJ, Wooley PH, Panayi G, Klavinskis LS.

Arthritis Rheum. 2005 Dec;52(12):3761-71.

PMID: 16329091 [PubMed - indexed for MEDLINE]

13:

A comparative study on intra-articular versus systemic gene electrotransfer in experimental arthritis.

Khoury M, Bigey P, Louis-Plence P, Noel D, Rhinn H, Scherman D, Jorgensen C, Apparailly F.

J Gene Med. 2006 Aug;8(8):1027-36.

PMID: 16733831 [PubMed - indexed for MEDLINE]

14:

A tumor necrosis factor receptor loop peptide mimic inhibits bone destruction to the same extent as anti-tumor necrosis factor monoclonal antibody in murine collagen-induced arthritis.

Saito H, Kojima T, Takahashi M, Horne WC, Baron R, Amagasa T, Ohya K, Aoki K.

Arthritis Rheum. 2007 Apr;56(4):1164-74.

PMID: 17393436 [PubMed - indexed for MEDLINE]

15:

Anti-arthritic effect of ginsenoside Rb1 on collagen induced arthritis in mice.

Kim HA, Kim S, Chang SH, Hwang HJ, Choi YN.

Int Immunopharmacol. 2007 Oct;7(10):1286-91. Epub 2007 Jun 26.

PMID: 17673143 [PubMed - indexed for MEDLINE]

16:

Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF-blocking agent.

Adriaansen J, Khoury M, de Cortie CJ, Fallaux FJ, Bigey P, Scherman D, Gould DJ, Chernajovsky Y, Apparailly F, Jorgensen C, Vervoordeldonk MJ, Tak PP.

Ann Rheum Dis. 2007 Sep;66(9):1143-50. Epub 2007 Mar 15.

PMID: 17363402 [PubMed - indexed for MEDLINE]

17:

Regulated expression of the interferon-beta gene in mice.

Harkins RN, Szymanski P, Petry H, Brooks A, Qian HS, Schaefer C, Kretschmer PJ, Orme A, Wang P, Rubanyi GM, Hermiston TW.

Gene Ther. 2008 Jan;15(1):1-11. Epub 2007 Jul 19.

PMID: 17637794 [PubMed - indexed for MEDLINE]

18:

Helper-dependent adenovirus for the gene therapy of proliferative retinopathies: stable gene transfer, regulated gene expression and therapeutic efficacy.

Lamartina S, Cimino M, Roscilli G, Dammassa E, Lazzaro D, Rota R, Ciliberto G, Toniatti C.

J Gene Med. 2007 Oct;9(10):862-74.

PMID: 17685494 [PubMed - indexed for MEDLINE]

19:

Gene targeting by ribozyme against TNF-alpha mRNA inhibits autoimmune arthritis.

Kumar R, Dammai V, Yadava PK, Kleinau S.

Gene Ther. 2005 Oct;12(20):1486-93.

PMID: 16034454 [PubMed - indexed for MEDLINE]

20:

Pathophysiological role of mast cells in collagen-induced arthritis: study with a cysteinyl leukotriene receptor antagonist, montelukast.

Shiota N, Shimoura K, Okunishi H.

Eur J Pharmacol. 2006 Oct 24;548(1-3):158-66. Epub 2006 Jul 28.

PMID: 16949072 [PubMed - indexed for MEDLINE]

Items 1 - 20 of 144
of 8Next