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Items 1 - 20 of 850
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1:

Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage.

Gebauer M, Saas J, Haag J, Dietz U, Takigawa M, Bartnik E, Aigner T.

Arthritis Res Ther. 2005;7(2):R274-84. Epub 2005 Jan 11.

PMID: 15743474 [PubMed - indexed for MEDLINE]

3:

Bone morphogenetic protein-mediating receptor-associated Smads as well as common Smad are expressed in human articular chondrocytes but not up-regulated or down-regulated in osteoarthritic cartilage.

Bau B, Haag J, Schmid E, Kaiser M, Gebhard PM, Aigner T.

J Bone Miner Res. 2002 Dec;17(12):2141-50.

PMID: 12469908 [PubMed - indexed for MEDLINE]

4:

Regulation of anabolic and catabolic gene expression in normal and osteoarthritic adult human articular chondrocytes by osteogenic protein-1.

Fan Z, Chubinskaya S, Rueger DC, Bau B, Haag J, Aigner T.

Clin Exp Rheumatol. 2004 Jan-Feb;22(1):103-6.

PMID: 15005012 [PubMed - indexed for MEDLINE]

5:

Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes.

Fukui N, Zhu Y, Maloney WJ, Clohisy J, Sandell LJ.

J Bone Joint Surg Am. 2003;85-A Suppl 3:59-66.

PMID: 12925611 [PubMed - indexed for MEDLINE]

6:

Subtractive gene expression profiling of articular cartilage and mesenchymal stem cells: serpins as cartilage-relevant differentiation markers.

Boeuf S, Steck E, Pelttari K, Hennig T, Buneb A, Benz K, Witte D, Sültmann H, Poustka A, Richter W.

Osteoarthritis Cartilage. 2008 Jan;16(1):48-60. Epub 2007 Jul 2.

PMID: 17604188 [PubMed - indexed for MEDLINE]

7:

Cartilage-derived morphogenetic protein-1 and -2 are endogenously expressed in healthy and osteoarthritic human articular chondrocytes and stimulate matrix synthesis.

Bobacz K, Gruber R, Soleiman A, Graninger WB, Luyten FP, Erlacher L.

Osteoarthritis Cartilage. 2002 May;10(5):394-401.

PMID: 12027540 [PubMed - indexed for MEDLINE]

8:

Clusterin expression in adult human normal and osteoarthritic articular cartilage.

Connor JR, Kumar S, Sathe G, Mooney J, O'Brien SP, Mui P, Murdock PR, Gowen M, Lark MW.

Osteoarthritis Cartilage. 2001 Nov;9(8):727-37.

PMID: 11795992 [PubMed - indexed for MEDLINE]

9:

YKL-39 (chitinase 3-like protein 2), but not YKL-40 (chitinase 3-like protein 1), is up regulated in osteoarthritic chondrocytes.

Knorr T, Obermayr F, Bartnik E, Zien A, Aigner T.

Ann Rheum Dis. 2003 Oct;62(10):995-8.

PMID: 12972480 [PubMed - indexed for MEDLINE]

10:

Comparison of the chondrosarcoma cell line SW1353 with primary human adult articular chondrocytes with regard to their gene expression profile and reactivity to IL-1beta.

Gebauer M, Saas J, Sohler F, Haag J, Söder S, Pieper M, Bartnik E, Beninga J, Zimmer R, Aigner T.

Osteoarthritis Cartilage. 2005 Aug;13(8):697-708.

PMID: 15950496 [PubMed - indexed for MEDLINE]

11:

Gene expression profiling of serum- and interleukin-1 beta-stimulated primary human adult articular chondrocytes--a molecular analysis based on chondrocytes isolated from one donor.

Aigner T, McKenna L, Zien A, Fan Z, Gebhard PM, Zimmer R.

Cytokine. 2005 Aug 7;31(3):227-40.

PMID: 15955710 [PubMed - indexed for MEDLINE]

12:

Differential expression of egr-1 in osteoarthritic compared to normal adult human articular cartilage.

Wang FL, Connor JR, Dodds RA, James IE, Kumar S, Zou C, Lark MW, Gowen M, Nuttall ME.

Osteoarthritis Cartilage. 2000 May;8(3):161-9.

PMID: 10806043 [PubMed - indexed for MEDLINE]

13:

Differential gene expression and regulation of the bone morphogenetic protein antagonists follistatin and gremlin in normal and osteoarthritic human chondrocytes and synovial fibroblasts.

Tardif G, Hum D, Pelletier JP, Boileau C, Ranger P, Martel-Pelletier J.

Arthritis Rheum. 2004 Aug;50(8):2521-30.

PMID: 15334466 [PubMed - indexed for MEDLINE]

14:

ADAM-12 (meltrin alpha) is involved in chondrocyte proliferation via cleavage of insulin-like growth factor binding protein 5 in osteoarthritic cartilage.

Okada A, Mochizuki S, Yatabe T, Kimura T, Shiomi T, Fujita Y, Matsumoto H, Sehara-Fujisawa A, Iwamoto Y, Okada Y.

Arthritis Rheum. 2008 Mar;58(3):778-89.

PMID: 18311789 [PubMed - indexed for MEDLINE]

15:

Freshly isolated osteoarthritic chondrocytes are catabolically more active than normal chondrocytes, but less responsive to catabolic stimulation with interleukin-1beta.

Fan Z, Bau B, Yang H, Soeder S, Aigner T.

Arthritis Rheum. 2005 Jan;52(1):136-43.

PMID: 15641077 [PubMed - indexed for MEDLINE]

16:

Peroxisome proliferator-activated receptor gamma1 expression is diminished in human osteoarthritic cartilage and is downregulated by interleukin-1beta in articular chondrocytes.

Afif H, Benderdour M, Mfuna-Endam L, Martel-Pelletier J, Pelletier JP, Duval N, Fahmi H.

Arthritis Res Ther. 2007;9(2):R31.

PMID: 17386086 [PubMed - indexed for MEDLINE]

17:

Differential expression of GADD45beta in normal and osteoarthritic cartilage: potential role in homeostasis of articular chondrocytes.

Ijiri K, Zerbini LF, Peng H, Otu HH, Tsuchimochi K, Otero M, Dragomir C, Walsh N, Bierbaum BE, Mattingly D, van Flandern G, Komiya S, Aigner T, Libermann TA, Goldring MB.

Arthritis Rheum. 2008 Jul;58(7):2075-87.

PMID: 18576389 [PubMed - indexed for MEDLINE]

18:

MMP-9/gelatinase B is a gene product of human adult articular chondrocytes and increased in osteoarthritic cartilage.

Söder S, Roach HI, Oehler S, Bau B, Haag J, Aigner T.

Clin Exp Rheumatol. 2006 May-Jun;24(3):302-4.

PMID: 16870098 [PubMed - indexed for MEDLINE]

19:

Toll-like receptors and chondrocytes: the lipopolysaccharide-induced decrease in cartilage matrix synthesis is dependent on the presence of toll-like receptor 4 and antagonized by bone morphogenetic protein 7.

Bobacz K, Sunk IG, Hofstaetter JG, Amoyo L, Toma CD, Akira S, Weichhart T, Saemann M, Smolen JS.

Arthritis Rheum. 2007 Jun;56(6):1880-93.

PMID: 17530716 [PubMed - indexed for MEDLINE]

20:

IL-1beta, but not BMP-7 leads to a dramatic change in the gene expression pattern of human adult articular chondrocytes--portraying the gene expression pattern in two donors.

Saas J, Haag J, Rueger D, Chubinskaya S, Sohler F, Zimmer R, Bartnik E, Aigner T.

Cytokine. 2006 Oct;36(1-2):90-9. Epub 2006 Dec 11.

PMID: 17161615 [PubMed - indexed for MEDLINE]

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