Arthritis Research & Therapy

Translating research into clinical practice

Arthritis Research & Therapy is an international, peer-reviewed online journal, publishing original research, reviews, commentaries and reports. The major focus of the journal is on cellular and molecular mechanisms of arthritis, musculoskeletal conditions and systemic autoimmune rheumatic diseases and translation of this knowledge into advances in clinical care. Original basic, translational laboratory and clinical research is considered for publication along with results of therapeutic trials.

Editors-in-Chief

Peter Lipsky, Charlottesville, Virginia
Ravinder Maini, London

Editorial Board | Instructions for authors | FAQ

Articles

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Research article

ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis

Wang CM, Ho HH, Chang SW, Jan Wu YJ, Lin JC, Chang PY, Wu J and Chen JY Arthritis Research & Therapy 2012, 14:R125 (25 May 2012)
Research article

Can erosions on MRI of the sacroiliac joints be reliably detected in patients with ankylosing spondylitis? A cross-sectional study

Weber U, Pedersen SJ, Ostergaard M, Rufibach K, Lambert RG and Maksymowych WP Arthritis Research & Therapy 2012, 14:R124 (24 May 2012)
Research article

Aberrant CD200/CD200R1 expression and function in systemic lupus erythematosus contributes to abnormal T cell responsiveness and dendritic cell activity

Li Y, Zhao L, Tong L, Qian S, Ren Y, Zhang L, Ding X, Chen Y et al. Arthritis Research & Therapy 2012, 14:R123 (23 May 2012)
Research article

Disruption of rhythms of molecular clocks in primary synovial fibroblasts of patients with osteoarthritis and rheumatoid arthritis, role of interleukin1 beta and tumor necrosis factor

Haas S and Straub RH Arthritis Research & Therapy 2012, 14:R122 (23 May 2012)
Research article

Limited effect of anti-rheumatic treatment on 15-prostaglandin dehydrogenase in rheumatoid arthritis synovial tissue

Gheorghe KR, Sadique S, Leclerc P, Idborg H, Wobst I, Catrina AI, Jakobsson PJ and Korotkova M Arthritis Research & Therapy 2012, 14:R121 (22 May 2012)
Research article

Enhanced susceptibility to lipopolysaccharide-induced arthritis and endotoxin shock in interleukin-32 alpha transgenic mice through induction of tumor necrosis factor alpha

Nakayama M, Niki Y, Kawasaki T, Takeda Y, Horiuchi K, Sasaki A, Okada Y, Umezawa K et al. Arthritis Research & Therapy 2012, 14:R120 (21 May 2012)
Research article

Serum amyloid A triggers the MSU-mediated mature interleukin-1beta production from human synovial fibroblasts

Migita K, Koga T, Satomura K, Izumi M, Torigoshi T, Maeda Y, Izumi Y, Jiuchi Y et al. Arthritis Research & Therapy 2012, 14:R119 (18 May 2012)
Editorial

Approaching the immunophysiology of steroid resistance

Bucala R Arthritis Research & Therapy 2012, 14:118 (18 May 2012)
Research article

T cell autoreactivity to citrullinated autoantigenic peptides in rheumatoid arthritis patients carrying HLA-DRB1 shared epitope alleles

Law SC, Street S, Yu CHA, Capini C, Ramnoruth S, Nel HJ, van Gorp E, Hyde C et al. Arthritis Research & Therapy 2012, 14:R118 (17 May 2012)
Research article

The role of Inflammation & Cardiovascular Disease Risk on Microvascular and Macrovascular Endothelial Function in Patients with Rheumatoid Arthritis: a Cross-sectional and Longitudinal Study

Sandoo A, Kitas GD, Carroll D and Veldhuijzen van Zanten JJCS Arthritis Research & Therapy 2012, 14:R117 (17 May 2012)
Editorial

Vaccination under TNF blockade - less effective, but worthwhile

Aringer M Arthritis Research & Therapy 2012, 14:117 (14 May 2012)
Research article

High-density lipoprotein cholesterol subfractions HDL2 and HDL3 are reduced in women with rheumatoid arthritis and may augment the cardiovascular risk of women with RA: a cross-sectional study

Arts E, Fransen J, Lemmers H, Stalenhoef A, Joosten L, van Riel P and Popa C Arthritis Research & Therapy 2012, 14:R116 (14 May 2012)
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Latest supplements

Volume 14 Suppl 2 (8 March 2012)

Proceedings of Osteorheumatology 2011: International Congress on Bone Involvement in Arthritis

Meeting abstracts
Santa Margherita Ligure, Italy. 13-14 October 2011

Volume 14 Suppl 1 (9 February 2012)

Proceedings of the 8th Global Arthritis Research Network (GARN) Meeting and 1st Bio-Rheumatology International Congress (BRIC)

Meeting abstracts
Tokyo, Japan. 14-16 November 2011

Latest issue

The complete issue of Arthritis Research & Therapy Volume 14 Issue 2 is now available.

Autoimmune Basis of Rheumatic Diseases

This comprehensive review series provides an in-depth discussion of recent developments in the pathogenesis, treatment and genetic background of four autoimmune rheumatic diseases: myositis, Sjögren's syndrome, systemic lupus erythematosus and vasculitis.

Reflections of a rheumatologist

The BRIC-GARN Meeting 2011: of mice and men

Latest review

All reviews, commentaries and reports published in Arthritis Research & Therapy become free to access 6 months after publication. See below for the latest free review.

Review

Piet Geusens, Willem F Lems

Arthritis Research & Therapy 2011, 13:242 (30 September 2011)

Abstract | Full text | PDF | PubMed

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Classical CVD disease risk may influence endothelial function more than disease-related markers of #inflammation in RA http://t.co/OAWFzXRd 9:30 AM May 22nd, 2012