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76.

368
Accesses

Review   Subscription Highly Accessed

Perspectives on epigenetic-based immune intervention for rheumatic diseases

Steven G Gray Arthritis Research & Therapy 2013, 15:207 (14 March 2013)

Abstract | Full text | PDF | PubMed

77.

368
Accesses

Research article   Open Access Highly Accessed

The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial

Michael A Becker, H Ralph Schumacher, Luis R Espinoza, Alvin F Wells, Patricia MacDonald, Eric Lloyd, Christopher Lademacher Arthritis Research & Therapy 2010, 12:R63 (6 April 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

78.

366
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Research article   Open Access Highly Accessed

Monitoring cartilage loss in the hands and wrists in rheumatoid arthritis with magnetic resonance imaging in a multi-center clinical trial: IMPRESS (NCT00425932)

Charles G Peterfy, Ewa Olech, Julie C DiCarlo, Joan T Merrill, Peter J Countryman, Norman B Gaylis Arthritis Research & Therapy 2013, 15:R44 (20 March 2013)

Abstract | Provisional PDF | PubMed

79.

367
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Review   Free Highly Accessed

Anti-inflammatory and immunosuppressive drugs and reproduction

Monika Østensen, Munther Khamashta, Michael Lockshin, Ann Parke, Antonio Brucato, Howard Carp, Andrea Doria, Raj Rai, Pierluigi Meroni, Irene Cetin, Ronald Derksen, Ware Branch, Mario Motta, Caroline Gordon, Guillermo Ruiz-Irastorza, Arsenio Spinillo, Deborah Friedman, Rolando Cimaz, Andrew Czeizel, Jean Piette, Ricard Cervera, Roger A Levy, Maurizio Clementi, Sara De Carolis, Michelle Petri, Yehuda Shoenfeld, David Faden, Guido Valesini, Angela Tincani Arthritis Research & Therapy 2006, 8:209 (11 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

80.

362
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Review   Free Highly Accessed

Mechanisms of tissue injury in lupus nephritis

Tamara K Nowling, Gary S Gilkeson Arthritis Research & Therapy 2011, 13:250 (21 December 2011)

Abstract | Full text | PDF | PubMed

81.

363
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Review   Free

B-cell depletion in SLE: clinical and trial experience with rituximab and ocrelizumab and implications for study design

Venkat Reddy, David Jayne, David Close, David Isenberg Arthritis Research & Therapy 2013, 15(Suppl 1):S2 (11 February 2013)

Abstract | Full text | PDF | PubMed

82.

360
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The association between rheumatoid arthritis and periodontal disease

Jacqueline Detert, Nicole Pischon, Gerd R Burmester, Frank Buttgereit Arthritis Research & Therapy 2010, 12:218 (22 October 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

83.

356
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Editorial   Free

The butterfly rash of lupus: An example of aposematism?

David S Pisetsky Arthritis Research & Therapy 2013, 15:106 (19 February 2013)

Abstract | Full text | PDF | PubMed

84.

355
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B-cell selection and the development of autoantibodies

Natalia V Giltiay, Craig P Chappell, Edward A Clark Arthritis Research & Therapy 2012, 14(Suppl 4):S1 (2 November 2012)

Abstract | Full text | PDF | PubMed

85.

344
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Inflammation associated anemia and ferritin as disease markers in SLE

Kamala Vanarsa, Yujin Ye, Jie Han, Chun Xie, Chandra Mohan, Tianfu Wu Arthritis Research & Therapy 2012, 14:R182 (7 August 2012)

Abstract | Full text | PDF | PubMed

86.

348
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Research article   Open Access

Periodic knee injections of collagen tripeptide delay cartilage degeneration in rabbit experimental osteoarthritis

Takuya Naraoka, Yasuyuki Ishibashi, Eiichi Tsuda, Yuji Yamamoto, Tomomi Kusumi, Satoshi Toh Arthritis Research & Therapy 2013, 15:R32 (22 February 2013)

Abstract | Full text | PDF | PubMed

87.

343
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Editorial   Free Highly Accessed

Autoimmunity induced by human cytomegalovirus in patients with systemic lupus erythematosus

Cecilia Söderberg-Nauclér Arthritis Research & Therapy 2012, 14:101 (23 January 2012)

Abstract | Full text | PDF | PubMed

88.

340
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Research article   Open Access Highly Accessed

The effect of smoking and alcohol consumption on markers of systemic inflammation, immunoglobulin levels and immune response following pneumococcal vaccination in patients with arthritis

Carmen Roseman, Lennart Truedsson, Meliha Kapetanovic Arthritis Research & Therapy 2012, 14:R170 (23 July 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology

89.

337
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Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy

Daniel Aeberli, Georg Schett Arthritis Research & Therapy 2013, 15:208 (21 March 2013)

Abstract | Full text | PDF | PubMed

90.

336
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Review   Free Highly Accessed

Fish oil: what the prescriber needs to know

Leslie G Cleland, Michael J James, Susanna M Proudman Arthritis Research & Therapy 2006, 8:202 (21 December 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

91.

335
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Research article   Open Access Highly Accessed

Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies

Lucas A Smolders, Björn P Meij, David Onis, Frank M Riemers, Niklas Bergknut, Richard Wubbolts, Guy CM Grinwis, Martin Houweling, Marian JA Groot Koerkamp, Dik van Leenen, Frank CP Holstege, Herman AW Hazewinkel, Laura B Creemers, Louis C Penning, Marianna A Tryfonidou Arthritis Research & Therapy 2013, 15:R23 (29 January 2013)

Abstract | Full text | PDF | PubMed

92.

330
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Unmet medical needs in systemic lupus erythematosus

Aisha Lateef, Michelle Petri Arthritis Research & Therapy 2012, 14(Suppl 4):S4 (18 December 2012)

Abstract | Full text | PDF | PubMed

93.

331
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Review   Free

Rationale of anti-CD19 immunotherapy: an option to target autoreactive plasma cells in autoimmunity

Henrik E Mei, Stefanie Schmidt, Thomas Dörner Arthritis Research & Therapy 2012, 14(Suppl 5):S1 (8 November 2012)

Abstract | Full text | PDF | PubMed

94.

329
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Research article   Open Access Highly Accessed

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis

Fiona E McCann, Andrew C Palfreeman, Melanie Andrews, Dany P Perocheau, Julia J Inglis, Peter Schafer, Marc Feldmann, Richard O Williams, Fionula M Brennan Arthritis Research & Therapy 2010, 12:R107 (2 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

95.

329
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Treatment of rheumatoid arthritis in the Medicare Current Beneficiary Survey

Daniel H Solomon, Edward Yelin, Jeffrey N Katz, Bing Lu, Tamara Shaykevich, John Z Ayanian Arthritis Research & Therapy 2013, 15:R43 (18 March 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Medicare patients with rheumatoid arthritis are less likely to receive disease-modifying anti-rheumatic drug (DMARD) treatment if they are not seeing a rheumatologist, have a lower income, or are older.

96.

327
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Research article   Open Access Highly Accessed

Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin?

Jan L Bjersing, Malin Erlandsson, Maria I Bokarewa, Kaisa Mannerkorpi Arthritis Research & Therapy 2013, 15:R34 (27 February 2013)

Abstract | Full text | PDF | PubMed

97.

324
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The genetics of lupus: a functional perspective

Sandra G Guerra, Timothy J Vyse, Deborah S Cunninghame Graham Arthritis Research & Therapy 2012, 14:211 (29 May 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

98.

321
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Research article   Open Access Highly Accessed

Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis - a systematic review of the literature

David F Ten Cate, Jolanda J Luime, Nanno Swen, Andreas H Gerards, Mike H De Jager, Natalja M Basoski, Johanna MW Hazes, Cees J Haagsma, Johannes WG Jacobs Arthritis Research & Therapy 2013, 15:R4 (8 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Ultrasonography has added value to clinical examination in diagnosing early rheumatoid arthritis and assessing remission, which could facilitate the provision of earlier and more effective treatments.

99.

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The clinical relevance of autoantibodies in scleroderma

Khanh T Ho, John D Reveille Arthritis Res Ther 2003, 5:80-93 (12 February 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

100.

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What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs

R Andrew Moore, Sheena Derry, Henry J McQuay, John Paling Arthritis Research & Therapy 2008, 10:R20 (7 February 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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