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	26. 687 Accesses	Research article RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis Maria J Martínez-Calatrava, Ivan Prieto-Potín, Jorge A Roman-Blas, Lidia Tardio, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2012, 14:R149 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	27. 649 Accesses	Review Common variable immunodeficiency - an update Ulrich Salzer, Klaus Warnatz, Hans Peter Arthritis Research & Therapy 2012, 14:223 (24 September 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	28. 642 Accesses	Research article Rpp25 is a major target of autoantibodies to the Th/To complex as measured by a novel chemiluminescent assay Michael Mahler, Cristina Gascon, Sima Patel, Angela Ceribelli, Marvin J Fritzler, Andreas Swart, Edward KL Chan, Minoru Satoh Arthritis Research & Therapy 2013, 15:R50 (12 April 2013) Abstract \| Full text \| PDF \| PubMed
	29. 617 Accesses	Review Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases Sherine E Gabriel, Kaleb Michaud Arthritis Research & Therapy 2009, 11:229 (19 May 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	30. 617 Accesses	Editorial Kidney disease in lupus is not always 'lupus nephritis' Hans-Joachim Anders, Jan J Weening Arthritis Research & Therapy 2013, 15:108 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
	31. 615 Accesses	Review microRNA-mediated regulation of innate immune response in rheumatic diseases Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen, Yihong Yao Arthritis Research & Therapy 2013, 15:210 (9 April 2013) Abstract \| Full text \| PDF \| PubMed
	32. 596 Accesses	Review Epidemiology and genetics of rheumatoid arthritis Alan J Silman, Jacqueline E Pearson Arthritis Res 2002, 4(Suppl 3):S265-S272 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	33. 588 Accesses	Review Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action Larry W Moreland Arthritis Res Ther 2003, 5:54-67 (14 January 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	34. 577 Accesses	Commentary What can rheumatologists learn from translational cancer therapy? Jonathan P Sherlock, Andrew D Filer, John D Isaacs, Christopher D Buckley Arthritis Research & Therapy 2013, 15:114 (1 May 2013) Abstract \| Full text \| PDF \| PubMed
	35. 575 Accesses	Review Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo Stadt, Stephan Ehl Arthritis Research & Therapy 2012, 14:213 (8 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	36. 572 Accesses	Review Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases? Udo Oppermann Arthritis Research & Therapy 2013, 15:209 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
	37. 569 Accesses	Review Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management Flavia V Castelino, John Varga Arthritis Research & Therapy 2010, 12:213 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	38. 563 Accesses	Primary research Monoarticular antigen-induced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats Gisela von Banchet, Peter K Petrow, Rolf Bräuer, Hans-Georg Schaible Arthritis Res 2000, 2:424-427 (3 August 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	39. 554 Accesses	Review Interleukin-6 and chronic inflammation Cem Gabay Arthritis Research & Therapy 2006, 8(Suppl 2):S3 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	40. 554 Accesses	Editorial Cardiovascular risk management in rheumatoid arthritis: are we still waiting for the first step? Mike JL Peters, Michael T Nurmohamed Arthritis Research & Therapy 2013, 15:111 (19 March 2013) Abstract \| Full text \| PDF \| PubMed
	41. 545 Accesses	Review B-cell targeted therapeutics in clinical development Stephan Blüml, Kathleen McKeever, Rachel Ettinger, Josef Smolen, Ronald Herbst Arthritis Research & Therapy 2013, 15(Suppl 1):S4 (4 April 2013) Abstract \| Full text \| PDF \| PubMed
	42. 523 Accesses	Review Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms? Sarah L Tansley, Neil J McHugh, Lucy R Wedderburn Arthritis Research & Therapy 2013, 15:211 (8 April 2013) Abstract \| Full text \| PDF \| PubMed
	43. 520 Accesses	Research article Vitamin D deficiency in undifferentiated connective tissue disease Eva Zold, Peter Szodoray, Janos Gaal, János Kappelmayer, Laszlo Csathy, Edit Gyimesi, Margit Zeher, Gyula Szegedi, Edit Bodolay Arthritis Research & Therapy 2008, 10:R123 (18 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary A study of 161 patients with undifferentiated connective tissue disease suggests that vitamin D deficiency may be associated with the disease progressing into well-defined connective tissue diseases such as rheumatoid arthritis.
	44. 518 Accesses	Research article Effects of rehabilitative interventions on pain, function and physical impairments in people with hand osteoarthritis: a systematic review Liuzhen Ye, Leonid Kalichman, Alicia Spittle, Fiona Dobson, Kim Bennell Arthritis Research & Therapy 2011, 13:R28 (18 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rehabilitative interventions such as exercise, splints, laser therapy and massage can improve pain, hand function, grip strength and range of motion in individuals with hand osteoarthritis.
	45. 511 Accesses	Research article Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials Winfried Häuser, Petra Klose, Jost Langhorst, Babak Moradi, Mario Steinbach, Marcus Schiltenwolf, Angela Busch Arthritis Research & Therapy 2010, 12:R79 (10 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	46. 511 Accesses	Review Osteoarthritis associated with estrogen deficiency Jorge A Roman-Blas, Santos Castañeda, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2009, 11:241 (21 September 2009) Abstract \| Full text \| PDF \| PubMed
	47. 494 Accesses	Research article Possible rheumatoid arthritis subtypes in terms of rheumatoid factor, depression, diagnostic delay and emotional expression: an exploratory case-control study Taavi Tillmann, Rajeev Krishnadas, Jonathan Cavanagh, KV Petrides Arthritis Research & Therapy 2013, 15:R45 (21 March 2013) Abstract \| Full text \| PDF \| PubMed
	48. 491 Accesses	Research article The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus Margareta Lantow, Ramya Sivakumar, Leilani Zeumer, Clive Wasserfall, Ying-Yi Zheng, Mark A Atkinson, Laurence Morel Arthritis Research & Therapy 2013, 15:R49 (8 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary B6.Sle2c2 mice are resistant to lupus due to a mutation in the granulocyte colony stimulating factor pathway, suggesting autoantibody production is inhibited by reduced neutrophil activation.
	49. 488 Accesses	Review An update on the hyper-IgE syndromes Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher Arthritis Research & Therapy 2012, 14:228 (30 November 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	50. 486 Accesses	Review Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models Simanta Pathak, Chandra Mohan Arthritis Research & Therapy 2011, 13:241 (30 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central