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	1. 1561 Accesses	Letter Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro' - authors' reply Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2013, 15:409 (24 May 2013) Abstract \| Full text \| PDF \| PubMed
	2. 1371 Accesses	Research article Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage Mathias Gebauer, Joachim Saas, Jochen Haag, Uwe Dietz, Masaharu Takigawa, Eckart Bartnik, Thomas Aigner Arthritis Res Ther 2005, 7:R274-R284 (11 January 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	3. 1165 Accesses	Research article Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence Laurent G Ameye, Winnie SS Chee Arthritis Research & Therapy 2006, 8:R127 (19 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4. 1047 Accesses	Review Microbes, the gut and ankylosing spondylitis Mary-Ellen Costello, Dirk Elewaut, Tony J Kenna, Matthew A Brown Arthritis Research & Therapy 2013, 15:214 (6 June 2013) Abstract \| Full text \| PDF \| PubMed
	5. 1023 Accesses	Review Cardiovascular risk in pediatric-onset rheumatological diseases Julie Barsalou, Timothy J Bradley, Earl D Silverman Arthritis Research & Therapy 2013, 15:212 (22 May 2013) Abstract \| Full text \| PDF \| PubMed
	6. 906 Accesses	Research article Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women Daniela Di Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling, Alicja Wolk Arthritis Research & Therapy 2013, 15:R56 (22 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Smoking only a few cigarettes a day more than doubles the risk of developing rheumatoid arthritis and although this risk will lower with time after smoking cessation, it can remain elevated 15 years later.
	7. 892 Accesses	Research article Early systemic sclerosis: marker autoantibodies and videocapillaroscopy patterns are each associated with distinct clinical, functional and cellular activation markers Gabriele Valentini, Antonella Marcoccia, Giovanna Cuomo, Serena Vettori, Michele Iudici, Francesco Bondanini, Carlo Santoriello, Aldo Ciani, Domenico Cozzolino, Giovanni Maria De Matteis, Salvatore Cappabianca, Filiberto Vitelli, Alberto Spano Arthritis Research & Therapy 2013, 15:R63 (29 May 2013) Abstract \| Provisional PDF \| PubMed
	8. 860 Accesses	Review Mechanisms of B cell autoimmunity in SLE Thomas Dörner, Claudia Giesecke, Peter E Lipsky Arthritis Research & Therapy 2011, 13:243 (27 October 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9. 826 Accesses	Research article Catabolic and anabolic periarticular bone changes in patients with rheumatoid arthritis: a computed tomography study on the role of age, disease duration and bone markers Sophie Aschenberg, Stephanie Finzel, Sarah Schmidt, Sebastian Kraus, Klaus Engelke, Matthias Englbrecht, Juergen Rech, Georg Schett Arthritis Research & Therapy 2013, 15:R62 (27 May 2013) Abstract \| Provisional PDF \| PubMed
	10. 803 Accesses	Review IL-10-producing regulatory B cells (B10 cells) in autoimmune disease Ioannis Kalampokis, Ayumi Yoshizaki, Thomas F Tedder Arthritis Research & Therapy 2013, 15(Suppl 1):S1 (11 February 2013) Abstract \| Full text \| PDF \| PubMed
	11. 800 Accesses	Review Degeneration of the intervertebral disc Jill PG Urban, Sally Roberts Arthritis Res Ther 2003, 5:120-130 (11 March 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	12. 775 Accesses	Research article A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin^®for treatment of osteoarthritis of the knee Krishanu Sengupta, Krishnaraju V Alluri, Andey Satish, Simanchala Mishra, Trimurtulu Golakoti, Kadainti VS Sarma, Dipak Dey, Siba P Raychaudhuri Arthritis Research & Therapy 2008, 10:R85 (30 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary An enriched extract of the Indian frankincense herb, Boswellia serrata reduced pain and improved the physical function of osteoarthritis patients, in a double blind, randomized, placebo controlled trial.
	13. 747 Accesses	Editorial Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation? Peter LEM van Lent, Wim B van den Berg Arthritis Research & Therapy 2013, 15:112 (20 March 2013) Abstract \| Full text \| PDF \| PubMed
	14. 747 Accesses	Research article A genetic role for macrophage migration inhibitory factor (MIF) in Adult-onset Still's disease Fang-Fang Wang, Xin-Fang Huang, Nan Shen, Lin Leng, Richard Bucala, Shun-Le Chen, Liang-Jing Lu Arthritis Research & Therapy 2013, 15:R65 (30 May 2013) Abstract \| Provisional PDF \| PubMed
	15. 745 Accesses	Letter Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro' Jing Ma, Ang Li, Shu Zhu, Xiao-Rui Cao, Guo-Xian Pei Arthritis Research & Therapy 2013, 15:408 (24 May 2013) Abstract \| Full text \| PDF \| PubMed
	16. 736 Accesses	Research article Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo John B Shepard, Jae-Wook Jeong, Nita J Maihle, Sean O'Brien, Caroline N Dealy Arthritis Research & Therapy 2013, 15:R60 (25 May 2013) Abstract \| Provisional PDF \| PubMed
	17. 732 Accesses	Research article Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens Jasmin B Kuemmerle-Deschner, Helmut Wittkowski, Pascal N Tyrrell, Ina Koetter, Peter Lohse, Katharina Ummenhofer, Fabian Rees, Sandra Hansmann, Assen Koitschev, Christoph Deuter, Anja Bialkowski, Dirk Foell, Susanne M Benseler Arthritis Research & Therapy 2013, 15:R64 (29 May 2013) Abstract \| Provisional PDF \| PubMed
	18. 724 Accesses	Research article Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment Eva Klingberg, Mattias Lorentzon, Dan Mellström, Mats Geijer, Jan Göthlin, Elisabet Hilme, Martin Hedberg, Hans Carlsten, Helena Forsblad-d'Elia Arthritis Research & Therapy 2012, 14:R108 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	19. 702 Accesses	Review Gout. Novel therapies for treatment of gout and hyperuricemia Robert Terkeltaub Arthritis Research & Therapy 2009, 11:236 (23 July 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	20. 689 Accesses	Research article Adenosine A_2Areceptors promote collagen production by a Fli1- and CTGF-mediated mechanism Edwin SL Chan, Hailing Liu, Patricia Fernandez, Alex Luna, Miguel Perez-Aso, Andreea M Bujor, Maria Trojanowska, Bruce N Cronstein Arthritis Research & Therapy 2013, 15:R58 (11 May 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.
	21. 690 Accesses	Research article IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis Thomas G Carlsen, Astrid Hjelholt, Anne G Jurik, Berit Schiøttz-Christensen, Anna Zejden, Gunna Christiansen, Bent Deleuran, Svend Birkelund Arthritis Research & Therapy 2013, 15:R61 (25 May 2013) Abstract \| Provisional PDF \| PubMed
	22. 636 Accesses	Review Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases Sherine E Gabriel, Kaleb Michaud Arthritis Research & Therapy 2009, 11:229 (19 May 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 617 Accesses	Review What are the immunological consequences of long-term use of biological therapies for juvenile idiopathic arthritis? Joost F Swart, Sytze de Roock, Nico M Wulffraat Arthritis Research & Therapy 2013, 15:213 (24 May 2013) Abstract \| Full text \| PDF \| PubMed
	24. 604 Accesses	Research article A novel in vitro bovine cartilage punch model for assessing the regeneration of focal cartilage defects with biocompatible bacterial nanocellulose David Pretzel, Stefanie Linss, Hannes Ahrem, Michaela Endres, Christian Kaps, Dieter Klemm, Raimund W. Kinne Arthritis Research & Therapy 2013, 15:R59 (14 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary In vitro bovine cartilage punch model is a novel tool developed to evaluate potential bio-materials for use in cartilage regeneration and repair.
	25. 601 Accesses	Review Complement and systemic lupus erythematosus Mark J Walport Arthritis Res 2002, 4(Suppl 3):S279-S293 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	26. 596 Accesses	Review The inflammatory process of gout and its treatment Bruce N Cronstein, Robert Terkeltaub Arthritis Research & Therapy 2006, 8(Suppl 1):S3 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	27. 546 Accesses	Primary research Monoarticular antigen-induced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats Gisela von Banchet, Peter K Petrow, Rolf Bräuer, Hans-Georg Schaible Arthritis Res 2000, 2:424-427 (3 August 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	28. 543 Accesses	Research article Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes Feng-Cheng Liu, Li-Feng Hung, Wan-Lin Wu, Deh-Ming Chang, Chuan-Yueh Huang, Jenn-Haung Lai, Ling-Jun Ho Arthritis Research & Therapy 2010, 12:R167 (8 September 2010) Abstract \| Full text \| PDF \| PubMed
	29. 537 Accesses	Review Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo Stadt, Stephan Ehl Arthritis Research & Therapy 2012, 14:213 (8 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	30. 531 Accesses	Research article Association between alcohol consumption and symptom severity and quality of life in patients with fibromyalgia Chul H Kim, Ann Vincent, Daniel J Clauw, Connie A Luedtke, Jeffrey M Thompson, Terry D Schneekloth, Terry H Oh Arthritis Research & Therapy 2013, 15:R42 (15 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Low to moderate alcohol consumption lessens symptom severity and betters quality of life for fibromyalgia patients when compared to no alcohol consumption.
	31. 529 Accesses	Review Developments in the clinical understanding of osteoarthritis David T Felson Arthritis Research & Therapy 2009, 11:203 (30 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	32. 501 Accesses	Research article The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties Robert M Bennett, Ronald Friend, Kim D Jones, Rachel Ward, Bobby K Han, Rebecca L Ross Arthritis Research & Therapy 2009, 11:R120 (10 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	33. 501 Accesses	Research article The effect of smoking and alcohol consumption on markers of systemic inflammation, immunoglobulin levels and immune response following pneumococcal vaccination in patients with arthritis Carmen Roseman, Lennart Truedsson, Meliha Kapetanovic Arthritis Research & Therapy 2012, 14:R170 (23 July 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	34. 473 Accesses	Review Interleukin-6 and chronic inflammation Cem Gabay Arthritis Research & Therapy 2006, 8(Suppl 2):S3 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	35. 468 Accesses	Research article Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion Ami A Shah, Elena Schiopu, Laura K Hummers, Michael Wade, Kristine Phillips, Cynthia Anderson, Robert Wise, Francesco Boin, James R Seibold, Fredrick Wigley, Kristan D Rollins Arthritis Research & Therapy 2013, 15:R54 (18 April 2013) Abstract \| Provisional PDF \| PubMed
	36. 468 Accesses	Review Epidemiology and genetics of rheumatoid arthritis Alan J Silman, Jacqueline E Pearson Arthritis Res 2002, 4(Suppl 3):S265-S272 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	37. 469 Accesses	Review microRNA-mediated regulation of innate immune response in rheumatic diseases Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen, Yihong Yao Arthritis Research & Therapy 2013, 15:210 (9 April 2013) Abstract \| Full text \| PDF \| PubMed
	38. 437 Accesses	Review Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management Flavia V Castelino, John Varga Arthritis Research & Therapy 2010, 12:213 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	39. 427 Accesses	Review Osteoarthritis associated with estrogen deficiency Jorge A Roman-Blas, Santos Castañeda, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2009, 11:241 (21 September 2009) Abstract \| Full text \| PDF \| PubMed
	40. 425 Accesses	Research article A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis Rui Liu, Qian Wu, Dinglei Su, Nan Che, Haifeng Chen, Linyu Geng, Jinyun Chen, Wanjun Chen, Xia Li, Lingyun Sun Arthritis Research & Therapy 2012, 14:R255 (23 November 2012) Abstract \| Full text \| PDF \| PubMed
	41. 421 Accesses	Review An update on the hyper-IgE syndromes Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher Arthritis Research & Therapy 2012, 14:228 (30 November 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	42. 419 Accesses	Review Rationale of anti-CD19 immunotherapy: an option to target autoreactive plasma cells in autoimmunity Henrik E Mei, Stefanie Schmidt, Thomas Dörner Arthritis Research & Therapy 2012, 14(Suppl 5):S1 (8 November 2012) Abstract \| Full text \| PDF \| PubMed
	43. 413 Accesses	Review Pathogenesis of tendinopathies: inflammation or degeneration? Michele Abate, Karin Gravare Silbernagel, Carl Siljeholm, Angelo Di Iorio, Daniele De Amicis, Vincenzo Salini, Suzanne Werner, Roberto Paganelli Arthritis Research & Therapy 2009, 11:235 (30 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	44. 411 Accesses	Research article Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials Winfried Häuser, Petra Klose, Jost Langhorst, Babak Moradi, Mario Steinbach, Marcus Schiltenwolf, Angela Busch Arthritis Research & Therapy 2010, 12:R79 (10 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	45. 412 Accesses	Research article Clinical features of symptomatic patellofemoral joint osteoarthritis George Peat, Rachel C Duncan, Laurence RJ Wood, Elaine Thomas, Sara Muller Arthritis Research & Therapy 2012, 14:R63 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
	46. 402 Accesses	Review Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action Larry W Moreland Arthritis Res Ther 2003, 5:54-67 (14 January 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	47. 391 Accesses	Research article Effects of rehabilitative interventions on pain, function and physical impairments in people with hand osteoarthritis: a systematic review Liuzhen Ye, Leonid Kalichman, Alicia Spittle, Fiona Dobson, Kim Bennell Arthritis Research & Therapy 2011, 13:R28 (18 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rehabilitative interventions such as exercise, splints, laser therapy and massage can improve pain, hand function, grip strength and range of motion in individuals with hand osteoarthritis.
	48. 381 Accesses	Research article The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial Michael A Becker, H Ralph Schumacher, Luis R Espinoza, Alvin F Wells, Patricia MacDonald, Eric Lloyd, Christopher Lademacher Arthritis Research & Therapy 2010, 12:R63 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	49. 381 Accesses	Research article Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis Fiona E McCann, Andrew C Palfreeman, Melanie Andrews, Dany P Perocheau, Julia J Inglis, Peter Schafer, Marc Feldmann, Richard O Williams, Fionula M Brennan Arthritis Research & Therapy 2010, 12:R107 (2 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	50. 381 Accesses	Research article Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study Ann-Charlotte Elkan, Beatrice Sjöberg, Björn Kolsrud, Bo Ringertz, Ingiäld Hafström, Johan Frostegård Arthritis Research & Therapy 2008, 10:R34 (18 March 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A gluten-free vegan diet induces potentially atheroprotective and anti-inflammatory changes in rheumatoid arthritis patients, including reduced low density lipoprotein (LDL) and oxidated LDL levels and raised natural antibodies against phosphorylcholine.