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	76. 3475 Accesses	Research article Nocturnal heart rate variability parameters as potential fibromyalgia biomarker: correlation with symptoms severity Claudia Lerma, Aline Martinez, Natllely Ruiz, Angelica Vargas, Oscar Infante, Manuel Martinez-Lavin Arthritis Research & Therapy 2011, 13:R185 (16 November 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Nocturnal heart rate variability parameters indicative of sympathetic predominance are significantly different in fibromyalgia patients compared to healthy individuals, and correlate with several symptoms including pain severity.
	77. 3448 Accesses	Review New developments in osteoarthritis. Posttraumatic osteoarthritis: pathogenesis and pharmacological treatment options Martin K Lotz Arthritis Research & Therapy 2010, 12:211 (28 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	78. 3443 Accesses	Commentary Promise and pitfalls of the Immunochip Adrian Cortes, Matthew A Brown Arthritis Research & Therapy 2011, 13:101 (1 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	79. 3442 Accesses	Research article Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis Mitsuhiko Sato, Kenzo Uchida, Hideaki Nakajima, Tsuyoshi Miyazaki, Alexander Guerrero, Shuji Watanabe, Sally Roberts, Hisatoshi Baba Arthritis Research & Therapy 2012, 14:R31 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| F1000
	80. 3440 Accesses	Research article Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen Julia J Inglis, Gabriel Criado, Mino Medghalchi, Melanie Andrews, Ann Sandison, Marc Feldmann, Richard O Williams Arthritis Research & Therapy 2007, 9:R113 (29 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary C57BL/6 mice may be useful for testing new therapeutics, particularly those directed against T cells, and investigating the action of current therapies in rheumatoid arthritis.
	81. 3388 Accesses	Research article Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis Gurkirpal Singh, Olivia Wu, Peter Langhorne, Rajan Madhok Arthritis Research & Therapy 2006, 8:R153 (22 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary NSAIDs have been shown to be associated with an increased risk of acute myocardial infarctions, suggesting they should be used with caution in those with risk factors for cardiovascular disease.
	82. 3356 Accesses	Review Disturbances of apoptotic cell clearance in systemic lupus erythematosus Wen-Hai Shao, Philip L Cohen Arthritis Research & Therapy 2011, 13:202 (28 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	83. 3337 Accesses	Commentary Biosimilars: a regulatory perspective from America Jonathan Kay Arthritis Research & Therapy 2011, 13:112 (12 May 2011) Abstract \| Full text \| PDF \| PubMed
	84. 3314 Accesses	Research article The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells Betty Y Chang, Min Huang, Michelle Francesco, Jun Chen, Jeremy Sokolove, Padmaja Magadala, William H Robinson, Joseph J Buggy Arthritis Research & Therapy 2011, 13:R115 (13 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	85. 3307 Accesses	Research article Anti-tumor necrosis factor therapy improves insulin resistance, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance Ilias Stagakis, George Bertsias, Stylianos Karvounaris, Melina Kavousanaki, Dimitra Virla, Amalia Raptopoulou, Dimitrios Kardassis, Dimitrios T Boumpas, Prodromos I Sidiropoulos Arthritis Research & Therapy 2012, 14:R141 (12 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Twelve weeks of anti-tumor necrosis factor (TNF) therapy improved insulin sensitivity, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance.
	86. 3288 Accesses	Review Abnormalities of T cell signaling in systemic lupus erythematosus Vaishali R Moulton, George C Tsokos Arthritis Research & Therapy 2011, 13:207 (17 March 2011) Abstract \| Full text \| PDF \| PubMed
	87. 3279 Accesses	Research article Integrated safety in tocilizumab clinical trials Michael H Schiff, Joel M Kremer, Angelika Jahreis, Emma Vernon, John D Isaacs, Ronald F van Vollenhoven Arthritis Research & Therapy 2011, 13:R141 (1 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	88. 3239 Accesses	Review Treatment targets in systemic lupus erythematosus: biology and clinical perspective Valentin Marian, Jennifer H Anolik Arthritis Research & Therapy 2012, 14(Suppl 4):S3 (30 November 2012) Abstract \| Full text \| PDF \| PubMed
	89. 3238 Accesses	Research article Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture — primary culture cells markedly differ from fourth-passage cells Thomas Zimmermann, Elke Kunisch, Robert Pfeiffer, Astrid Hirth, Hans-Detlev Stahl, Ulrich Sack, Anke Laube, Eckehard Liesaus, Andreas Roth, Ernesta Palombo-Kinne, Frank Emmrich, Raimund W Kinne Arthritis Res 2001, 3:72-76 (21 November 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	90. 3234 Accesses	Research article Ultrasound of metacarpophalangeal joints is a sensitive and reliable endpoint for drug therapies in rheumatoid arthritis: results of a randomized, two-center placebo-controlled study Matthew W Seymour, Stephen Kelly, Chan R Beals, Marie-Pierre Malice, James A Bolognese, Bernard J Dardzinski, Amy S Cheng, Corinne E Cummings, Steven S Smugar, Catherine McClinton, Amy Fox, William M Dooley, Constantino Pitzalis, Peter C Taylor Arthritis Research & Therapy 2012, 14:R198 (12 September 2012) Abstract \| Full text \| PDF \| PubMed
	91. 3222 Accesses	Research article Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models Jun Soo Bang, Da Hee Oh, Hyun Mi Choi, Bong-Jun Sur, Sung-Jig Lim, Jung Yeon Kim, Hyung-In Yang, Myung Chul Yoo, Dae-Hyun Hahm, Kyoung Soo Kim Arthritis Research & Therapy 2009, 11:R49 (30 March 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	92. 3207 Accesses	Research article Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration Shiro Suzuki, Takeshi Muneta, Kunikazu Tsuji, Shizuko Ichinose, Hatsune Makino, Akihiro Umezawa, Ichiro Sekiya Arthritis Research & Therapy 2012, 14:R136 (7 June 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Aggregated mesenchymal stem cells are a useful source for cartilage regeneration, as they are easy to prepare, have high chondrogenic potential and attach efficiently.
	93. 3164 Accesses	Research article Can erosions on MRI of the sacroiliac joints be reliably detected in patients with ankylosing spondylitis? - A cross-sectional study Ulrich Weber, Susanne J Pedersen, Mikkel Østergaard, Kaspar Rufibach, Robert GW Lambert, Walter P Maksymowych Arthritis Research & Therapy 2012, 14:R124 (24 May 2012) Abstract \| Full text \| PDF \| PubMed
	94. 3157 Accesses	Primary research Monoarticular antigen-induced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats Gisela von Banchet, Peter K Petrow, Rolf Bräuer, Hans-Georg Schaible Arthritis Res 2000, 2:424-427 (3 August 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	95. 3127 Accesses	Research article Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes Feng-Cheng Liu, Li-Feng Hung, Wan-Lin Wu, Deh-Ming Chang, Chuan-Yueh Huang, Jenn-Haung Lai, Ling-Jun Ho Arthritis Research & Therapy 2010, 12:R167 (8 September 2010) Abstract \| Full text \| PDF \| PubMed
	96. 3121 Accesses	Research article Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies Chih Liu, Stephanie Tangsombatvisit, Jacob M Rosenberg, Gil Mandelbaum, Emily C Gillespie, Or P Gozani, Ash A Alizadeh, Paul J Utz Arthritis Research & Therapy 2012, 14:R25 (2 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	97. 3112 Accesses	Research article miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4 Jing Li, Jingang Huang, Liming Dai, Degang Yu, Qian Chen, Xiaoling Zhang, Kerong Dai Arthritis Research & Therapy 2012, 14:R75 (16 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The microRNA miR-146a may reduce cellular response to transforming growth factor-beta through targeted inhibition of Smad4 in cartilage, thus increasing vascular endothelial growth factor levels, and increasing chondrocyte apoptosis.
	98. 3107 Accesses	Research article Vitamin D deficiency in rheumatoid arthritis: prevalence, determinants and associations with disease activity and disability Maurizio Rossini, Susanna Maddali Bongi, Giovanni La Montagna, Giovanni Minisola, Nazzarena Malavolta, Luigi Bernini, Enrico Cacace, Luigi Sinigaglia, Ombretta Di Munno, Silvano Adami Arthritis Research & Therapy 2010, 12:R216 (29 November 2010) Abstract \| Full text \| PDF \| PubMed \| F1000
	99. 3025 Accesses	Research article Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study Tuulikki Sokka, Sergio Toloza, Maurizio Cutolo, Hannu Kautiainen, Heidi Makinen, Feride Gogus, Vlado Skakic, Humeira Badsha, Tõnu Peets, Asta Baranauskaite, Pál Géher, Ilona Újfalussy, Fotini N Skopouli, Maria Mavrommati, Rieke Alten, Christof Pohl, Jean Sibilia, Andrea Stancati, Fausto Salaffi, Wojciech Romanowski, Danuta Zarowny-Wierzbinska, Dan Henrohn, Barry Bresnihan, Patricia Minnock, Lene Knudsen, Johannes WG Jacobs, Jaime Calvo-Alen, Juris Lazovskis, Geraldo Pinheiro, Dmitry Karateev, Daina Andersone, Sylejman Rexhepi, Yusuf Yazici, Theodore Pincus, the QUEST-RA Group et al. Arthritis Research & Therapy 2009, 11:R7 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rheumatoid arthritis was more severe in women in an analysis of more than 6,000 patients, although the effects of gender on standard disease activity measures may explain the difference.
	100. 3021 Accesses	Review Current treatment of hepatitis C-associated rheumatic diseases Clodoveo Ferri, Marco Sebastiani, Alessandro Antonelli, Michele Colaci, A Manfredi, Dilia Giuggioli Arthritis Research & Therapy 2012, 14:215 (25 June 2012) Abstract \| Full text \| PDF \| PubMed