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	1. 10789 Accesses	Research article Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence Laurent G Ameye, Winnie SS Chee Arthritis Research & Therapy 2006, 8:R127 (19 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	2. 9407 Accesses	Review Degeneration of the intervertebral disc Jill PG Urban, Sally Roberts Arthritis Res Ther 2003, 5:120-130 (11 March 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	3. 8859 Accesses	Research article Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage Mathias Gebauer, Joachim Saas, Jochen Haag, Uwe Dietz, Masaharu Takigawa, Eckart Bartnik, Thomas Aigner Arthritis Res Ther 2005, 7:R274-R284 (11 January 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	4. 8627 Accesses	Research article A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin^®for treatment of osteoarthritis of the knee Krishanu Sengupta, Krishnaraju V Alluri, Andey Satish, Simanchala Mishra, Trimurtulu Golakoti, Kadainti VS Sarma, Dipak Dey, Siba P Raychaudhuri Arthritis Research & Therapy 2008, 10:R85 (30 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary An enriched extract of the Indian frankincense herb, Boswellia serrata reduced pain and improved the physical function of osteoarthritis patients, in a double blind, randomized, placebo controlled trial.
	5. 7549 Accesses	Review Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases Sherine E Gabriel, Kaleb Michaud Arthritis Research & Therapy 2009, 11:229 (19 May 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6. 7139 Accesses	Research article Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study Ann-Charlotte Elkan, Beatrice Sjöberg, Björn Kolsrud, Bo Ringertz, Ingiäld Hafström, Johan Frostegård Arthritis Research & Therapy 2008, 10:R34 (18 March 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A gluten-free vegan diet induces potentially atheroprotective and anti-inflammatory changes in rheumatoid arthritis patients, including reduced low density lipoprotein (LDL) and oxidated LDL levels and raised natural antibodies against phosphorylcholine.
	7. 6933 Accesses	Research article Vitamin D deficiency in undifferentiated connective tissue disease Eva Zold, Peter Szodoray, Janos Gaal, János Kappelmayer, Laszlo Csathy, Edit Gyimesi, Margit Zeher, Gyula Szegedi, Edit Bodolay Arthritis Research & Therapy 2008, 10:R123 (18 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary A study of 161 patients with undifferentiated connective tissue disease suggests that vitamin D deficiency may be associated with the disease progressing into well-defined connective tissue diseases such as rheumatoid arthritis.
	8. 6831 Accesses	Research article A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis Rui Liu, Qian Wu, Dinglei Su, Nan Che, Haifeng Chen, Linyu Geng, Jinyun Chen, Wanjun Chen, Xia Li, Lingyun Sun Arthritis Research & Therapy 2012, 14:R255 (23 November 2012) Abstract \| Full text \| PDF \| PubMed
	9. 6781 Accesses	Review Mechanisms of B cell autoimmunity in SLE Thomas Dörner, Claudia Giesecke, Peter E Lipsky Arthritis Research & Therapy 2011, 13:243 (27 October 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	10. 6400 Accesses	Review Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management Flavia V Castelino, John Varga Arthritis Research & Therapy 2010, 12:213 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	11. 6343 Accesses	Research article Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment Eva Klingberg, Mattias Lorentzon, Dan Mellström, Mats Geijer, Jan Göthlin, Elisabet Hilme, Martin Hedberg, Hans Carlsten, Helena Forsblad-d'Elia Arthritis Research & Therapy 2012, 14:R108 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	12. 6224 Accesses	Review Epidemiology and genetics of rheumatoid arthritis Alan J Silman, Jacqueline E Pearson Arthritis Res 2002, 4(Suppl 3):S265-S272 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	13. 6211 Accesses	Review Interleukin-6 and chronic inflammation Cem Gabay Arthritis Research & Therapy 2006, 8(Suppl 2):S3 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	14. 5815 Accesses	Research article The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties Robert M Bennett, Ronald Friend, Kim D Jones, Rachel Ward, Bobby K Han, Rebecca L Ross Arthritis Research & Therapy 2009, 11:R120 (10 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	15. 5709 Accesses	Research article Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis Fiona E McCann, Andrew C Palfreeman, Melanie Andrews, Dany P Perocheau, Julia J Inglis, Peter Schafer, Marc Feldmann, Richard O Williams, Fionula M Brennan Arthritis Research & Therapy 2010, 12:R107 (2 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	16. 5649 Accesses	Research article TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2012, 14:R242 (7 November 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	17. 5637 Accesses	Review The inflammatory process of gout and its treatment Bruce N Cronstein, Robert Terkeltaub Arthritis Research & Therapy 2006, 8(Suppl 1):S3 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	18. 5539 Accesses	Review Adult mesenchymal stem cells and cell-based tissue engineering Rocky S Tuan, Genevieve Boland, Richard Tuli Arthritis Res Ther 2003, 5:32-45 (11 December 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	19. 5512 Accesses	Research article Restoration of regulatory and effector T cell balance and B cell homeostasis in systemic lupus erythematosus patients through vitamin D supplementation Benjamin Terrier, Nicolas Derian, Yoland Schoindre, Wahiba Chaara, Guillaume Geri, Noël Zahr, Kubéraka Mariampillai, Michelle Rosenzwajg, Wassila Carpentier, Lucile Musset, Jean-Charles Piette, Adrien Six, David Klatzmann, David Saadoun, Cacoub Patrice, Nathalie Costedoat-Chalumeau Arthritis Research & Therapy 2012, 14:R221 (17 October 2012) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology \| Editor’s summary Vitamin D supplementation in systemic lupus erythematosus (SLE) patients caused a reduction in B memory cells and effector T cells, and an increase in Tregs, suggesting vitamin D provides beneficial immunological effects for SLE.
	20. 5457 Accesses	Research article Clinical features of symptomatic patellofemoral joint osteoarthritis George Peat, Rachel C Duncan, Laurence RJ Wood, Elaine Thomas, Sara Muller Arthritis Research & Therapy 2012, 14:R63 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
	21. 5376 Accesses	Review Platelet-rich plasma therapy - future or trend? Robinder S Dhillon, Edward M Schwarz, Michael D Maloney Arthritis Research & Therapy 2012, 14:219 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	22. 5370 Accesses	Review The genetics of lupus: a functional perspective Sandra G Guerra, Timothy J Vyse, Deborah S Cunninghame Graham Arthritis Research & Therapy 2012, 14:211 (29 May 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 5368 Accesses	Review Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models Simanta Pathak, Chandra Mohan Arthritis Research & Therapy 2011, 13:241 (30 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	24. 5303 Accesses	Research article Distinguishing fibromyalgia from rheumatoid arthritis and systemic lupus in clinical questionnaires: an analysis of the revised Fibromyalgia Impact Questionnaire (FIQR) and its variant, the Symptom Impact Questionnaire (SIQR), along with pain locations Ronald Friend, Robert M Bennett Arthritis Research & Therapy 2011, 13:R58 (8 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A combination of 2 questions from the symptom impact questionnaire plus pain in four locations identified the correct diagnosis in 97% of subjects with fibromyalgia, rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
	25. 5163 Accesses	Review Complement and systemic lupus erythematosus Mark J Walport Arthritis Res 2002, 4(Suppl 3):S279-S293 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	26. 5008 Accesses	Research article Effects of rehabilitative interventions on pain, function and physical impairments in people with hand osteoarthritis: a systematic review Liuzhen Ye, Leonid Kalichman, Alicia Spittle, Fiona Dobson, Kim Bennell Arthritis Research & Therapy 2011, 13:R28 (18 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rehabilitative interventions such as exercise, splints, laser therapy and massage can improve pain, hand function, grip strength and range of motion in individuals with hand osteoarthritis.
	27. 4977 Accesses	Research article Antibodies of IgG, IgA and IgM isotypes against cyclic citrullinated peptide precede the development of rheumatoid arthritis Heidi Kokkonen, Mohammed Mullazehi, Ewa Berglin, Göran Hallmans, Göran Wadell, Johan Rönnelid, Solbritt Rantapää-Dahlqvist Arthritis Research & Therapy 2011, 13:R13 (3 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	28. 4893 Accesses	Research article Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model Anika I Tsuchida, Michiel Beekhuizen, Marijn Rutgers, Gerjo JVM van Osch, Joris EJ Bekkers, Arjan GJ Bot, Bernd Geurts, Wouter JA Dhert, Daniel BF Saris, Laura B Creemers Arthritis Research & Therapy 2012, 14:R262 (3 December 2012) Abstract \| Full text \| PDF \| PubMed
	29. 4886 Accesses	Research article TLR4-mediated IL-12 production enhances IFN-γ and IL-1β production, which inhibits TGF-β production and promotes antibody-induced joint inflammation Hye Kim, Doo Chung Arthritis Research & Therapy 2012, 14:R210 (4 October 2012) Abstract \| Full text \| PDF \| PubMed
	30. 4856 Accesses	Review Fish oil: what the prescriber needs to know Leslie G Cleland, Michael J James, Susanna M Proudman Arthritis Research & Therapy 2006, 8:202 (21 December 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	31. 4837 Accesses	Review Pathogenesis of tendinopathies: inflammation or degeneration? Michele Abate, Karin Gravare Silbernagel, Carl Siljeholm, Angelo Di Iorio, Daniele De Amicis, Vincenzo Salini, Suzanne Werner, Roberto Paganelli Arthritis Research & Therapy 2009, 11:235 (30 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	32. 4835 Accesses	Review A concise history of gout and hyperuricemia and their treatment George Nuki, Peter A Simkin Arthritis Research & Therapy 2006, 8(Suppl 1):S1 (12 April 2006) Abstract \| Full text \| PDF \| PubMed
	33. 4834 Accesses	Research article CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts Chun-Han Hou, Chih-Hsin Tang, Chin-Jung Hsu, Sheng-Mon Hou, Ju-Fang Liu Arthritis Research & Therapy 2013, 15:R19 (23 January 2013) Abstract \| Full text \| PDF \| PubMed
	34. 4723 Accesses	Review Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo Stadt, Stephan Ehl Arthritis Research & Therapy 2012, 14:213 (8 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	35. 4610 Accesses	Research article Therapeutic potential of human umbilical cord mesenchymal stem cells in the treatment of rheumatoid arthritis Yanying Liu, Rong Mu, Shiyao Wang, Li Long, Xia Liu, Ru Li, Jian Sun, Jianping Guo, Xiaoping Zhang, Jing Guo, Ping Yu, Chunlei Li, Xiangyuan Liu, Zhenyu Huang, Dapeng Wang, Hu Li, Zhifeng Gu, Bing Liu, Zhanguo Li Arthritis Research & Therapy 2010, 12:R210 (16 November 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	36. 4550 Accesses	Research article Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis Marina G Kazantseva, John Highton, Lisa K Stamp, Paul A Hessian Arthritis Research & Therapy 2012, 14:R208 (4 October 2012) Abstract \| Full text \| PDF \| PubMed
	37. 4516 Accesses	Research article Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women Daniela Di Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling, Alicja Wolk Arthritis Research & Therapy 2013, 15:R56 (22 April 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Smoking only a few cigarettes a day more than doubles the risk of developing rheumatoid arthritis and although this risk will lower with time after smoking cessation, it can remain elevated 15 years later.
	38. 4505 Accesses	Research article The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial Michael A Becker, H Ralph Schumacher, Luis R Espinoza, Alvin F Wells, Patricia MacDonald, Eric Lloyd, Christopher Lademacher Arthritis Research & Therapy 2010, 12:R63 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	39. 4483 Accesses	Review Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation Catherine M Kolf, Elizabeth Cho, Rocky S Tuan Arthritis Research & Therapy 2007, 9:204 (19 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	40. 4424 Accesses	Research article Enhanced interleukin-1β production of PBMCs from patients with gout after stimulation with Toll-like receptor-2 ligands and urate crystals Eleni E Mylona, Maria Mouktaroudi, Tania O Crisan, Stamatoula Makri, Aikaterini Pistiki, Marianna Georgitsi, Athina Savva, Mihai G Netea, Jos WM van der Meer, Evangelos J Giamarellos-Bourboulis, Leo AB Joosten Arthritis Research & Therapy 2012, 14:R158 (4 July 2012) Abstract \| Full text \| PDF \| PubMed
	41. 4271 Accesses	Research article Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study Antonio Naranjo, Tuulikki Sokka, Miguel A Descalzo, Jaime Calvo-Alén, Kim Hørslev-Petersen, Reijo K Luukkainen, Bernard Combe, Gerd R Burmester, Joe Devlin, Gianfranco Ferraccioli, Alessia Morelli, Monique Hoekstra, Maria Majdan, Stefan Sadkiewicz, Miguel Belmonte, Ann-Carin Holmqvist, Ernest Choy, Recep Tunc, Aleksander Dimic, Martin Bergman, Sergio Toloza, Theodore Pincus, the QUEST-RA Group Arthritis Research & Therapy 2008, 10:R30 (6 March 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Treating rheumatoid arthritis with disease-modifying anti-rheumatic drugs, such as methotrexate, reduces the risk of heart attacks and strokes, data from a study of 4,363 patients across 15 countries shows.
	42. 4257 Accesses	Review Common variable immunodeficiency - an update Ulrich Salzer, Klaus Warnatz, Hans Peter Arthritis Research & Therapy 2012, 14:223 (24 September 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	43. 4234 Accesses	Research article A randomized controlled trial of qigong for fibromyalgia Mary Lynch, Jana Sawynok, Chok Hiew, Dana Marcon Arthritis Research & Therapy 2012, 14:R178 (3 August 2012) Abstract \| Full text \| PDF \| PubMed
	44. 4199 Accesses	Review Early diagnosis to enable early treatment of pre-osteoarthritis Constance R Chu, Ashley A Williams, Christian H Coyle, Megan E Bowers Arthritis Research & Therapy 2012, 14:212 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	45. 4199 Accesses	Research article Sustained rheumatoid arthritis remission is uncommon in clinical practice Femke HM Prince, Vivian P Bykerk, Nancy A Shadick, Bing Lu, Jing Cui, Michelle Frits, Christine K Iannaccone, Michael E Weinblatt, Daniel H Solomon Arthritis Research & Therapy 2012, 14:R68 (19 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In clinical practice only a minority of patients with rheumatoid arthritis (RA) are in sustained remission, suggesting strict monitoring is required even once remission is reached.
	46. 4199 Accesses	Review Osteoarthritis associated with estrogen deficiency Jorge A Roman-Blas, Santos Castañeda, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2009, 11:241 (21 September 2009) Abstract \| Full text \| PDF \| PubMed
	47. 4097 Accesses	Research article IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis Young-Mee Moon, Bo-Young Yoon, Yang-Mi Her, Hye-Joa Oh, Jae-Seon Lee, Kyoung-Woon Kim, Seon-Yeong Lee, Yun-Ju Woo, Kyung-Su Park, Sung-Hwan Park, Ho-Youn Kim, Mi-La Cho Arthritis Research & Therapy 2012, 14:R246 (13 November 2012) Abstract \| Full text \| PDF \| PubMed
	48. 4086 Accesses	Research article Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID) Hans-Peter Tony, Gerd Burmester, Hendrik Schulze-Koops, Mathias Grunke, Joerg Henes, Ina Kötter, Judith Haas, Leonore Unger, Svjetlana Lovric, Marion Haubitz, Rebecca Fischer-Betz, Gamal Chehab, Andrea Rubbert-Roth, Christof Specker, Jutta Weinerth, Julia Holle, Ulf Müller-Ladner, Ramona König, Christoph Fiehn, Philip Burgwinkel, Klemens Budde, Helmut Sörensen, Michael Meurer, Martin Aringer, Bernd Kieseier, Cornelia Erfurt-Berge, Michael Sticherling, Roland Veelken, Ulf Ziemann, Frank Strutz et al. Arthritis Research & Therapy 2011, 13:R75 (13 May 2011) Abstract \| Full text \| PDF \| PubMed
	49. 4035 Accesses	Review The association between rheumatoid arthritis and periodontal disease Jacqueline Detert, Nicole Pischon, Gerd R Burmester, Frank Buttgereit Arthritis Research & Therapy 2010, 12:218 (22 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	50. 4022 Accesses	Research article Association between alcohol consumption and symptom severity and quality of life in patients with fibromyalgia Chul H Kim, Ann Vincent, Daniel J Clauw, Connie A Luedtke, Jeffrey M Thompson, Terry D Schneekloth, Terry H Oh Arthritis Research & Therapy 2013, 15:R42 (15 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Low to moderate alcohol consumption lessens symptom severity and betters quality of life for fibromyalgia patients when compared to no alcohol consumption.