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51.

15908
Accesses

Review   Free Highly Accessed

Interleukin-6: discovery of a pleiotropic cytokine

Tadamitsu Kishimoto Arthritis Research & Therapy 2006, 8(Suppl 2):S2 (28 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

52.

15855
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Research article   Open Access Highly Accessed

Relationship between physical activity and stiff or painful joints in mid-aged women and older women: a 3-year prospective study

Kristiann C Heesch, Yvette D Miller, Wendy J Brown Arthritis Research & Therapy 2007, 9:R34 (29 March 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

53.

15618
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Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics

Robert Terkeltaub, David A Bushinsky, Michael A Becker Arthritis Research & Therapy 2006, 8(Suppl 1):S4 (12 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

54.

15551
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Research article   Open Access Highly Accessed

Anti-TNF-α antibody allows healing of joint damage in polyarthritic transgenic mice

David J Shealy, Paul H Wooley, Eva Emmell, Amy Volk, Amy Rosenberg, George Treacy, Carrie L Wagner, Lois Mayton, Don E Griswold, Xiao-yu R Song Arthritis Res 2002, 4:R7 (28 June 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

55.

15507
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Research article   Open Access Highly Accessed

Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study

Steeve Tat, Jean-Pierre Pelletier, Josep Vergés, Daniel Lajeunesse, Eulàlia Montell, Hassan Fahmi, Martin Lavigne, Johanne Martel-Pelletier Arthritis Research & Therapy 2007, 9:R117 (9 November 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A combination of glucosamine sulphate and chondroitin sulphate markedly reduces the resorptive activity of subchondral bone osteoblasts, suggesting a positive effect on early bone structural changes in osteoarthritis.

56.

15476
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Research article   Open Access Highly Accessed

A critical appraisal of guidelines for the management of knee osteoarthritis using Appraisal of Guidelines Research and Evaluation criteria

Stéphane Poitras, Jérôme Avouac, Michel Rossignol, Bernard Avouac, Christine Cedraschi, Margareta Nordin, Chantal Rousseaux, Sylvie Rozenberg, Bernard Savarieau, Philippe Thoumie, Jean-Pierre Valat, Éric Vignon, Pascal Hilliquin Arthritis Research & Therapy 2007, 9:R126 (6 December 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Guidelines for treating knee osteoarthritis were found to lack educational information and differ in treatments addressed when they were reviewed using the Appraisal of Guidelines Research and Evaluation (AGREE) criteria.

57.

15429
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Arthritis and Pain. Neurogenic origin of joint pain

Jason J McDougall Arthritis Research & Therapy 2006, 8:220 (10 November 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

58.

15283
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Macrophages in rheumatoid arthritis

Raimund W Kinne, Rolf Bräuer, Bruno Stuhlmüller, Ernesta Palombo-Kinne, Gerd-R Burmester Arthritis Res 2000, 2:189-202 (12 April 2000)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

59.

15281
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Negative regulation of cytokine signaling and immune responses by SOCS proteins

Akihiko Yoshimura, Hitomi Nishinakamura, Yumiko Matsumura, Toshikatsu Hanada Arthritis Research & Therapy 2005, 7:100-110 (30 March 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

60.

15234
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Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis

Fiona E McCann, Andrew C Palfreeman, Melanie Andrews, Dany P Perocheau, Julia J Inglis, Peter Schafer, Marc Feldmann, Richard O Williams, Fionula M Brennan Arthritis Research & Therapy 2010, 12:R107 (2 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

61.

15226
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Arthritis and pain. Psychosocial aspects in the management of arthritis pain

Catherine L Backman Arthritis Research & Therapy 2006, 8:221 (5 December 2006)

Abstract | Full text | PDF | PubMed | 1 comment

62.

15153
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Research article   Open Access Highly Accessed

Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports

R Andrew Moore, Sheena Derry, Geoffrey T Makinson, Henry J McQuay Arthritis Research & Therapy 2005, 7:R644-R665 (24 March 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

63.

15130
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The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties

Robert M Bennett, Ronald Friend, Kim D Jones, Rachel Ward, Bobby K Han, Rebecca L Ross Arthritis Research & Therapy 2009, 11:R120 (10 August 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

64.

15118
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Magnetic resonance imaging in psoriatic arthritis: a review of the literature

Fiona McQueen, Marissa Lassere, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:207 (23 March 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

65.

15109
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Is juvenile rheumatoid arthritis/juvenile idiopathic arthritis different from rheumatoid arthritis?

Sampath Prahalad, David N Glass Arthritis Res 2002, 4(Suppl 3):303-310 (24 July 2002)

Abstract | Full text | PDF

66.

15060
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Signaling for survival and apoptosis in the immune system

Tak W Mak, Wen-Chen Yeh Arthritis Res 2002, 4(Suppl 3):S243-S252 (9 May 2002)

Abstract | Full text | PDF | PubMed

67.

15026
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The clinical relevance of autoantibodies in scleroderma

Khanh T Ho, John D Reveille Arthritis Res Ther 2003, 5:80-93 (12 February 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

68.

14873
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Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study

Tuulikki Sokka, Sergio Toloza, Maurizio Cutolo, Hannu Kautiainen, Heidi Makinen, Feride Gogus, Vlado Skakic, Humeira Badsha, Tõnu Peets, Asta Baranauskaite, Pál Géher, Ilona Újfalussy, Fotini N Skopouli, Maria Mavrommati, Rieke Alten, Christof Pohl, Jean Sibilia, Andrea Stancati, Fausto Salaffi, Wojciech Romanowski, Danuta Zarowny-Wierzbinska, Dan Henrohn, Barry Bresnihan, Patricia Minnock, Lene Knudsen, Johannes WG Jacobs, Jaime Calvo-Alen, Juris Lazovskis, Geraldo Pinheiro, Dmitry Karateev, Daina Andersone, Sylejman Rexhepi, Yusuf Yazici, Theodore Pincus, the QUEST-RA Group et al. Arthritis Research & Therapy 2009, 11:R7 (14 January 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Rheumatoid arthritis was more severe in women in an analysis of more than 6,000 patients, although the effects of gender on standard disease activity measures may explain the difference.

69.

14707
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Research article   Open Access Highly Accessed

Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols

Eleni Douni, Petros P Sfikakis, Sylva Haralambous, Peter Fernandes, George Kollias Arthritis Res Ther 2004, 6:R65-R72 (7 November 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

70.

14690
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Matrix metalloproteinases in arthritic disease

Gillian Murphy, Vera Knäuper, Susan Atkinson, George Butler, William English, Mike Hutton, Jan Stracke, Ian Clark Arthritis Res 2002, 4(Suppl 3):S39-S49 (9 May 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

71.

14686
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Research article   Open Access

Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture — primary culture cells markedly differ from fourth-passage cells

Thomas Zimmermann, Elke Kunisch, Robert Pfeiffer, Astrid Hirth, Hans-Detlev Stahl, Ulrich Sack, Anke Laube, Eckehard Liesaus, Andreas Roth, Ernesta Palombo-Kinne, Frank Emmrich, Raimund W Kinne Arthritis Res 2001, 3:72-76 (21 November 2000)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

72.

14651
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A critical appraisal of clinical practice guidelines for the treatment of lower-limb osteoarthritis

James N Pencharz, Elizabeth Grigoriadis, Gwenderlyn F Jansz, Claire Bombardier Arthritis Res 2002, 4:36-44 (16 October 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

73.

14631
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Gout. Novel therapies for treatment of gout and hyperuricemia

Robert Terkeltaub Arthritis Research & Therapy 2009, 11:236 (23 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

74.

14460
Accesses

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DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment

Bert Vander Cruyssen, Stijn Van Looy, Bart Wyns, Rene Westhovens, Patrick Durez, Filip Van den Bosch, Eric M Veys, Herman Mielants, Luc De Clerck, Anne Peretz, Michel Malaise, Leon Verbruggen, Nathan Vastesaeger, Anja Geldhof, Luc Boullart, Filip De Keyser Arthritis Research & Therapy 2005, 7:R1063-R1071 (8 July 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

75.

14458
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Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value

Martinus AM van Boekel, Erik R Vossenaar, Frank HJ van den Hoogen, Walther J van Venrooij Arthritis Res 2002, 4:87-93 (6 November 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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