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	51. 15769 Accesses	Review Interleukin-6: discovery of a pleiotropic cytokine Tadamitsu Kishimoto Arthritis Research & Therapy 2006, 8(Suppl 2):S2 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	52. 15766 Accesses	Research article Relationship between physical activity and stiff or painful joints in mid-aged women and older women: a 3-year prospective study Kristiann C Heesch, Yvette D Miller, Wendy J Brown Arthritis Research & Therapy 2007, 9:R34 (29 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	53. 15497 Accesses	Review Recent developments in our understanding of the renal basis of hyperuricemia and the development of novel antihyperuricemic therapeutics Robert Terkeltaub, David A Bushinsky, Michael A Becker Arthritis Research & Therapy 2006, 8(Suppl 1):S4 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	54. 15464 Accesses	Research article Anti-TNF-α antibody allows healing of joint damage in polyarthritic transgenic mice David J Shealy, Paul H Wooley, Eva Emmell, Amy Volk, Amy Rosenberg, George Treacy, Carrie L Wagner, Lois Mayton, Don E Griswold, Xiao-yu R Song Arthritis Res 2002, 4:R7 (28 June 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	55. 15422 Accesses	Research article Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study Steeve Tat, Jean-Pierre Pelletier, Josep Vergés, Daniel Lajeunesse, Eulàlia Montell, Hassan Fahmi, Martin Lavigne, Johanne Martel-Pelletier Arthritis Research & Therapy 2007, 9:R117 (9 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A combination of glucosamine sulphate and chondroitin sulphate markedly reduces the resorptive activity of subchondral bone osteoblasts, suggesting a positive effect on early bone structural changes in osteoarthritis.
	56. 15320 Accesses	Research article A critical appraisal of guidelines for the management of knee osteoarthritis using Appraisal of Guidelines Research and Evaluation criteria Stéphane Poitras, Jérôme Avouac, Michel Rossignol, Bernard Avouac, Christine Cedraschi, Margareta Nordin, Chantal Rousseaux, Sylvie Rozenberg, Bernard Savarieau, Philippe Thoumie, Jean-Pierre Valat, Éric Vignon, Pascal Hilliquin Arthritis Research & Therapy 2007, 9:R126 (6 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Guidelines for treating knee osteoarthritis were found to lack educational information and differ in treatments addressed when they were reviewed using the Appraisal of Guidelines Research and Evaluation (AGREE) criteria.
	57. 15273 Accesses	Review Arthritis and Pain. Neurogenic origin of joint pain Jason J McDougall Arthritis Research & Therapy 2006, 8:220 (10 November 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	58. 15203 Accesses	Review Negative regulation of cytokine signaling and immune responses by SOCS proteins Akihiko Yoshimura, Hitomi Nishinakamura, Yumiko Matsumura, Toshikatsu Hanada Arthritis Research & Therapy 2005, 7:100-110 (30 March 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	59. 15071 Accesses	Review Macrophages in rheumatoid arthritis Raimund W Kinne, Rolf Bräuer, Bruno Stuhlmüller, Ernesta Palombo-Kinne, Gerd-R Burmester Arthritis Res 2000, 2:189-202 (12 April 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	60. 15065 Accesses	Review Arthritis and pain. Psychosocial aspects in the management of arthritis pain Catherine L Backman Arthritis Research & Therapy 2006, 8:221 (5 December 2006) Abstract \| Full text \| PDF \| PubMed \| 1 comment
	61. 15025 Accesses	Review Magnetic resonance imaging in psoriatic arthritis: a review of the literature Fiona McQueen, Marissa Lassere, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:207 (23 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	62. 15022 Accesses	Review Signaling for survival and apoptosis in the immune system Tak W Mak, Wen-Chen Yeh Arthritis Res 2002, 4(Suppl 3):S243-S252 (9 May 2002) Abstract \| Full text \| PDF \| PubMed
	63. 14992 Accesses	Research article Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports R Andrew Moore, Sheena Derry, Geoffrey T Makinson, Henry J McQuay Arthritis Research & Therapy 2005, 7:R644-R665 (24 March 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	64. 14967 Accesses	Review Is juvenile rheumatoid arthritis/juvenile idiopathic arthritis different from rheumatoid arthritis? Sampath Prahalad, David N Glass Arthritis Res 2002, 4(Suppl 3):303-310 (24 July 2002) Abstract \| Full text \| PDF
	65. 14861 Accesses	Research article Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis Fiona E McCann, Andrew C Palfreeman, Melanie Andrews, Dany P Perocheau, Julia J Inglis, Peter Schafer, Marc Feldmann, Richard O Williams, Fionula M Brennan Arthritis Research & Therapy 2010, 12:R107 (2 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	66. 14734 Accesses	Review The clinical relevance of autoantibodies in scleroderma Khanh T Ho, John D Reveille Arthritis Res Ther 2003, 5:80-93 (12 February 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	67. 14666 Accesses	Research article Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA Study Tuulikki Sokka, Sergio Toloza, Maurizio Cutolo, Hannu Kautiainen, Heidi Makinen, Feride Gogus, Vlado Skakic, Humeira Badsha, Tõnu Peets, Asta Baranauskaite, Pál Géher, Ilona Újfalussy, Fotini N Skopouli, Maria Mavrommati, Rieke Alten, Christof Pohl, Jean Sibilia, Andrea Stancati, Fausto Salaffi, Wojciech Romanowski, Danuta Zarowny-Wierzbinska, Dan Henrohn, Barry Bresnihan, Patricia Minnock, Lene Knudsen, Johannes WG Jacobs, Jaime Calvo-Alen, Juris Lazovskis, Geraldo Pinheiro, Dmitry Karateev, Daina Andersone, Sylejman Rexhepi, Yusuf Yazici, Theodore Pincus, the QUEST-RA Group et al. Arthritis Research & Therapy 2009, 11:R7 (14 January 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rheumatoid arthritis was more severe in women in an analysis of more than 6,000 patients, although the effects of gender on standard disease activity measures may explain the difference.
	68. 14665 Accesses	Research article The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties Robert M Bennett, Ronald Friend, Kim D Jones, Rachel Ward, Bobby K Han, Rebecca L Ross Arthritis Research & Therapy 2009, 11:R120 (10 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	69. 14605 Accesses	Research article Attenuation of inflammatory polyarthritis in TNF transgenic mice by diacerein: comparative analysis with dexamethasone, methotrexate and anti-TNF protocols Eleni Douni, Petros P Sfikakis, Sylva Haralambous, Peter Fernandes, George Kollias Arthritis Res Ther 2004, 6:R65-R72 (7 November 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	70. 14579 Accesses	Research article Isolation and characterization of rheumatoid arthritis synovial fibroblasts from primary culture — primary culture cells markedly differ from fourth-passage cells Thomas Zimmermann, Elke Kunisch, Robert Pfeiffer, Astrid Hirth, Hans-Detlev Stahl, Ulrich Sack, Anke Laube, Eckehard Liesaus, Andreas Roth, Ernesta Palombo-Kinne, Frank Emmrich, Raimund W Kinne Arthritis Res 2001, 3:72-76 (21 November 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	71. 14571 Accesses	Review Matrix metalloproteinases in arthritic disease Gillian Murphy, Vera Knäuper, Susan Atkinson, George Butler, William English, Mike Hutton, Jan Stracke, Ian Clark Arthritis Res 2002, 4(Suppl 3):S39-S49 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	72. 14554 Accesses	Review A critical appraisal of clinical practice guidelines for the treatment of lower-limb osteoarthritis James N Pencharz, Elizabeth Grigoriadis, Gwenderlyn F Jansz, Claire Bombardier Arthritis Res 2002, 4:36-44 (16 October 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	73. 14358 Accesses	Research article DAS28 best reflects the physician's clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment Bert Vander Cruyssen, Stijn Van Looy, Bart Wyns, Rene Westhovens, Patrick Durez, Filip Van den Bosch, Eric M Veys, Herman Mielants, Luc De Clerck, Anne Peretz, Michel Malaise, Leon Verbruggen, Nathan Vastesaeger, Anja Geldhof, Luc Boullart, Filip De Keyser Arthritis Research & Therapy 2005, 7:R1063-R1071 (8 July 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	74. 14329 Accesses	Review Autoantibody systems in rheumatoid arthritis: specificity, sensitivity and diagnostic value Martinus AM van Boekel, Erik R Vossenaar, Frank HJ van den Hoogen, Walther J van Venrooij Arthritis Res 2002, 4:87-93 (6 November 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	75. 14281 Accesses	Review The paradigm of IL-6: from basic science to medicine Tetsuji Naka, Norihiro Nishimoto, Tadamitsu Kishimoto Arthritis Res 2002, 4(Suppl 3):S233-S242 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	76. 14280 Accesses	Review Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases Nathan J Zvaifler Arthritis Research & Therapy 2006, 8:210 (9 May 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	77. 14235 Accesses	Review Biology of RANK, RANKL, and osteoprotegerin Brendan F Boyce, Lianping Xing Arthritis Research & Therapy 2007, 9(Suppl 1):S1 (29 June 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	78. 14208 Accesses	Research article Hormone replacement therapy in rheumatoid arthritis is associated with lower serum levels of soluble IL-6 receptor and higher insulin-like growth factor 1 Helena d'Elia, Lars-Åke Mattsson, Claes Ohlsson, Elisabeth Nordborg, Hans Carlsten Arthritis Res Ther 2003, 5:R202-R209 (1 May 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	79. 14074 Accesses	Research article A pilot study of IL-1 inhibition by anakinra in acute gout Alexander So, Thibaut De Smedt, Sylvie Revaz, Jürg Tschopp Arthritis Research & Therapy 2007, 9:R28 (12 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In a pilot study on 10 patients with gouty arthritis, IL-1 blockade with anakinra gave rapid relief of inflammatory symptoms where standard treatments had failed or were not tolerated.
	80. 14050 Accesses	Review Biology and therapy of fibromyalgia. Stress, the stress response system, and fibromyalgia Manuel Martinez-Lavin Arthritis Research & Therapy 2007, 9:216 (6 July 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	81. 14032 Accesses	Review Gout. Novel therapies for treatment of gout and hyperuricemia Robert Terkeltaub Arthritis Research & Therapy 2009, 11:236 (23 July 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	82. 14000 Accesses	Research article Rheumatoid arthritis associated autoantibodies in patients with synovitis of recent onset Raphaela Goldbach-Mansky, Jennifer Lee, Angela McCoy, Joseph Hoxworth, Cheryl Yarboro, Josef S Smolen, Günter Steiner, Antony Rosen, Cindy Zhang, Henri A Ménard, Zhi Jie Zhou, Timo Palosuo, Walther J Van Venrooij, Ronald L Wilder, John H Klippel, H Ralph Schumacher, Hani S El-Gabalawy Arthritis Res 2000, 2:236-243 (31 March 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	83. 13981 Accesses	Review Oxidation in rheumatoid arthritis Carol A Hitchon, Hani S El-Gabalawy Arthritis Res Ther 2004, 6:265-278 (13 October 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	84. 13974 Accesses	Commentary Does a positive anti-CCP test identify a distinct arthritis entity? Thomas Skogh Arthritis Research & Therapy 2005, 7:230-232 (16 September 2005) Abstract \| Full text \| PDF \| PubMed
	85. 13954 Accesses	Review Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management Flavia V Castelino, John Varga Arthritis Research & Therapy 2010, 12:213 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	86. 13705 Accesses	Research article The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial Michael A Becker, H Ralph Schumacher, Luis R Espinoza, Alvin F Wells, Patricia MacDonald, Eric Lloyd, Christopher Lademacher Arthritis Research & Therapy 2010, 12:R63 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	87. 13651 Accesses	Research article Identification of blood biomarkers of rheumatoid arthritis by transcript profiling of peripheral blood mononuclear cells from the rat collagen-induced arthritis model Jianyong Shou, Christopher M Bull, Li Li, Hui-Rong Qian, Tao Wei, Shuang Luo, Douglas Perkins, Patricia J Solenberg, Seng-Lai Tan, Xin-Yi Chen, Neal W Roehm, Jeffrey A Wolos, Jude E Onyia Arthritis Research & Therapy 2006, 8:R28 (10 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	88. 13627 Accesses	Research article Switching TNF antagonists in patients with chronic arthritis: an observational study of 488 patients over a four-year period Juan J Gomez-Reino, Loreto Carmona, the BIOBADASER Group Arthritis Research & Therapy 2006, 8:R29 (6 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	89. 13610 Accesses	Review Perspectives for TNF-α-targeting therapies Hanns-Martin Lorenz, Joachim R Kalden Arthritis Res 2002, 4(Suppl 3):S17-S24 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	90. 13371 Accesses	Review Angiogenesis in rheumatoid arthritis Ewa M Paleolog Arthritis Res 2002, 4(Suppl 3):S81-S90 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	91. 13357 Accesses	Review The life cycle of chondrocytes in the developing skeleton Lillian Shum, Glen Nuckolls Arthritis Res 2002, 4:94-106 (8 November 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	92. 13244 Accesses	Review The evolving clinical profile of abatacept (CTLA4–Ig): a novel co-stimulatory modulator for the treatment of rheumatoid arthritis Eric M Ruderman, Richard M Pope Arthritis Research & Therapy 2005, 7(Suppl 2):S21-S25 (16 March 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	93. 13166 Accesses	Research article Collagen-induced arthritis in C57BL/6 mice is associated with a robust and sustained T-cell response to type II collagen Julia J Inglis, Gabriel Criado, Mino Medghalchi, Melanie Andrews, Ann Sandison, Marc Feldmann, Richard O Williams Arthritis Research & Therapy 2007, 9:R113 (29 October 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary C57BL/6 mice may be useful for testing new therapeutics, particularly those directed against T cells, and investigating the action of current therapies in rheumatoid arthritis.
	94. 13067 Accesses	Research article Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells Kutty Nandakumar, Johan Bäcklund, Mikael Vestberg, Rikard Holmdahl Arthritis Res Ther 2004, 6:R544-R550 (23 September 2004) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	95. 13011 Accesses	Research article Forced mobilization accelerates pathogenesis: characterization of a preclinical surgical model of osteoarthritis C Thomas G Appleton, David D McErlain, Vasek Pitelka, Neil Schwartz, Suzanne M Bernier, James L Henry, David W Holdsworth, Frank Beier Arthritis Research & Therapy 2007, 9:R13 (6 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	96. 13010 Accesses	Research article Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides Merete Pedersen, Søren Jacobsen, Mette Klarlund, Bo V Pedersen, Allan Wiik, Jan Wohlfahrt, Morten Frisch Arthritis Research & Therapy 2006, 8:R133 (27 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	97. 13001 Accesses	Research article Rheumatic Diseases in China Qing Zeng, Ren Chen, John Darmawan, Zheng Xiao, Su Chen, Richard Wigley, Shun Le Chen, Nai Zhang Arthritis Research & Therapy 2008, 10:R17 (31 January 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A large population study found that the incidence of certain rheumatic diseases in China is becoming more like that of Western countries, but different joints are affected compared to Caucasian populations.
	98. 12992 Accesses	Review Epstein–Barr virus and rheumatoid arthritis: is there a link? Karen H Costenbader, Elizabeth W Karlson Arthritis Research & Therapy 2006, 8:204 (16 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	99. 12949 Accesses	Supplement Autoantibodies in rheumatoid arthritis and their clinical significance Günter Steiner, Josef Smolen Arthritis Res 2002, 4(Suppl 2):S1-S5 (26 April 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	100. 12925 Accesses	Research article Masitinib in the treatment of active rheumatoid arthritis: results of a multicentre, open-label, dose-ranging, phase 2a study Jacques Tebib, Xavier Mariette, Pierre Bourgeois, René-Marc Flipo, Philippe Gaudin, Xavier Le Loët, Paul Gineste, Laurent Guy, Colin D Mansfield, Alain Moussy, Patrice Dubreuil, Olivier Hermine, Jean Sibilia Arthritis Research & Therapy 2009, 11:R95 (23 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A small clinical trial has shown masitinib to be generally well tolerated and effective in the treatment of rheumatoid arthritis, indicating the need for further placebo-controlled studies.