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1.

96759
Accesses

Research article   Open Access Highly Accessed

Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage

Mathias Gebauer, Joachim Saas, Jochen Haag, Uwe Dietz, Masaharu Takigawa, Eckart Bartnik, Thomas Aigner Arthritis Res Ther 2005, 7:R274-R284 (11 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

2.

46638
Accesses

Research article   Open Access Highly Accessed

Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence

Laurent G Ameye, Winnie SS Chee Arthritis Research & Therapy 2006, 8:R127 (19 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

3.

38115
Accesses

Review   Free Highly Accessed

Degeneration of the intervertebral disc

Jill PG Urban, Sally Roberts Arthritis Res Ther 2003, 5:120-130 (11 March 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

4.

36295
Accesses

Review   Free Highly Accessed

Adult mesenchymal stem cells and cell-based tissue engineering

Rocky S Tuan, Genevieve Boland, Richard Tuli Arthritis Res Ther 2003, 5:32-45 (11 December 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

5.

36091
Accesses

Research article   Open Access Highly Accessed

A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee

Krishanu Sengupta, Krishnaraju V Alluri, Andey Satish, Simanchala Mishra, Trimurtulu Golakoti, Kadainti VS Sarma, Dipak Dey, Siba P Raychaudhuri Arthritis Research & Therapy 2008, 10:R85 (30 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 |  Editor’s summary

An enriched extract of the Indian frankincense herb, Boswellia serrata reduced pain and improved the physical function of osteoarthritis patients, in a double blind, randomized, placebo controlled trial.

6.

33638
Accesses

Research article   Open Access Highly Accessed

Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study

Ann-Charlotte Elkan, Beatrice Sjöberg, Björn Kolsrud, Bo Ringertz, Ingiäld Hafström, Johan Frostegård Arthritis Research & Therapy 2008, 10:R34 (18 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

A gluten-free vegan diet induces potentially atheroprotective and anti-inflammatory changes in rheumatoid arthritis patients, including reduced low density lipoprotein (LDL) and oxidated LDL levels and raised natural antibodies against phosphorylcholine.

7.

32039
Accesses

Review   Free Highly Accessed

Epidemiology, risk factors, and lifestyle modifications for gout

Kenneth G Saag, Hyon Choi Arthritis Research & Therapy 2006, 8(Suppl 1):S2 (12 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

8.

31796
Accesses

Review   Free

Epidemiology and genetics of rheumatoid arthritis

Alan J Silman, Jacqueline E Pearson Arthritis Res 2002, 4(Suppl 3):S265-S272 (9 May 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

28909
Accesses

Primary research   Open Access

Monoarticular antigen-induced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats

Gisela von Banchet, Peter K Petrow, Rolf Bräuer, Hans-Georg Schaible Arthritis Res 2000, 2:424-427 (3 August 2000)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

10.

28720
Accesses

Review   Free Highly Accessed

Fish oil: what the prescriber needs to know

Leslie G Cleland, Michael J James, Susanna M Proudman Arthritis Research & Therapy 2006, 8:202 (21 December 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

11.

25435
Accesses

Research article   Open Access Highly Accessed

Vitamin D deficiency in undifferentiated connective tissue disease

Eva Zold, Peter Szodoray, Janos Gaal, János Kappelmayer, Laszlo Csathy, Edit Gyimesi, Margit Zeher, Gyula Szegedi, Edit Bodolay Arthritis Research & Therapy 2008, 10:R123 (18 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 |  Editor’s summary

A study of 161 patients with undifferentiated connective tissue disease suggests that vitamin D deficiency may be associated with the disease progressing into well-defined connective tissue diseases such as rheumatoid arthritis.

12.

25192
Accesses

Review   Free Highly Accessed

Anti-inflammatory and immunosuppressive drugs and reproduction

Monika Østensen, Munther Khamashta, Michael Lockshin, Ann Parke, Antonio Brucato, Howard Carp, Andrea Doria, Raj Rai, Pierluigi Meroni, Irene Cetin, Ronald Derksen, Ware Branch, Mario Motta, Caroline Gordon, Guillermo Ruiz-Irastorza, Arsenio Spinillo, Deborah Friedman, Rolando Cimaz, Andrew Czeizel, Jean Piette, Ricard Cervera, Roger A Levy, Maurizio Clementi, Sara De Carolis, Michelle Petri, Yehuda Shoenfeld, David Faden, Guido Valesini, Angela Tincani Arthritis Research & Therapy 2006, 8:209 (11 May 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

24674
Accesses

Review   Free Highly Accessed

Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation

Catherine M Kolf, Elizabeth Cho, Rocky S Tuan Arthritis Research & Therapy 2007, 9:204 (19 February 2007)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

14.

24606
Accesses

Review   Free Highly Accessed

Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases

Sherine E Gabriel, Kaleb Michaud Arthritis Research & Therapy 2009, 11:229 (19 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

15.

24475
Accesses

Research article   Open Access Highly Accessed

Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin

Karim Raza, Francesco Falciani, S John Curnow, Emma J Ross, Chi-Yeung Lee, Arne N Akbar, Janet M Lord, Caroline Gordon, Christopher D Buckley, Mike Salmon Arthritis Research & Therapy 2005, 7:R784-R795 (7 April 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Patients with early arthritis who subsequently develop rheumatoid arthritis (RA) have a distinct but transient synovial fluid cytokine profile. This not only gives clues about the pathology of RA, but also has potential for use as a diagnostic tool.

16.

24010
Accesses

Research article   Open Access Highly Accessed

Aerobic exercise and its impact on musculoskeletal pain in older adults: a 14 year prospective, longitudinal study

Bonnie Bruce, James F Fries, Deborah P Lubeck Arthritis Research & Therapy 2005, 7:R1263-R1270 (19 September 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

Pain increases with age, however people who regularly carry out brisk aerobic exercise such as running, experience 25% less musculoskeletal pain in old age than those who exercise infrequently.

17.

23298
Accesses

Review   Free Highly Accessed

Interleukin-6 and chronic inflammation

Cem Gabay Arthritis Research & Therapy 2006, 8(Suppl 2):S3 (28 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

18.

23008
Accesses

Review   Free Highly Accessed

Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action

Larry W Moreland Arthritis Res Ther 2003, 5:54-67 (14 January 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

19.

22539
Accesses

Review   Free Highly Accessed

The inflammatory process of gout and its treatment

Bruce N Cronstein, Robert Terkeltaub Arthritis Research & Therapy 2006, 8(Suppl 1):S3 (12 April 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

22398
Accesses

Review   Free Highly Accessed

Articular cartilage and changes in Arthritis: Cell biology of osteoarthritis

Linda J Sandell, Thomas Aigner Arthritis Res 2001, 3:107-113 (22 January 2001)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

21.

21846
Accesses

Review   Free Highly Accessed

The molecular mechanism of osteoclastogenesis in rheumatoid arthritis

Nobuyuki Udagawa, Shigeru Kotake, Naoyuki Kamatani, Naoyuki Takahashi, Tatsuo Suda Arthritis Res 2002, 4:281-289 (12 April 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

22.

21042
Accesses

Review   Free Highly Accessed

Mesenchymal stem cells in arthritic diseases

Faye H Chen, Rocky S Tuan Arthritis Research & Therapy 2008, 10:223 (10 October 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

23.

20776
Accesses

Review   Free Highly Accessed

A concise history of gout and hyperuricemia and their treatment

George Nuki, Peter A Simkin Arthritis Research & Therapy 2006, 8(Suppl 1):S1 (12 April 2006)

Abstract | Full text | PDF | PubMed

24.

20696
Accesses

Research article   Open Access Highly Accessed

Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study

Antonio Naranjo, Tuulikki Sokka, Miguel A Descalzo, Jaime Calvo-Alén, Kim Hørslev-Petersen, Reijo K Luukkainen, Bernard Combe, Gerd R Burmester, Joe Devlin, Gianfranco Ferraccioli, Alessia Morelli, Monique Hoekstra, Maria Majdan, Stefan Sadkiewicz, Miguel Belmonte, Ann-Carin Holmqvist, Ernest Choy, Recep Tunc, Aleksander Dimic, Martin Bergman, Sergio Toloza, Theodore Pincus, the QUEST-RA Group Arthritis Research & Therapy 2008, 10:R30 (6 March 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Treating rheumatoid arthritis with disease-modifying anti-rheumatic drugs, such as methotrexate, reduces the risk of heart attacks and strokes, data from a study of 4,363 patients across 15 countries shows.

25.

20243
Accesses

Supplement   Free

How does infliximab work in rheumatoid arthritis?

Ravinder N Maini, Marc Feldmann Arthritis Res 2002, 4(Suppl 2):S22-S28 (27 March 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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