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1.

1561
Accesses

Letter   Free Highly Accessed

Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro' - authors' reply

Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2013, 15:409 (24 May 2013)

Abstract | Full text | PDF | PubMed

2.

1371
Accesses

Research article   Open Access Highly Accessed

Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage

Mathias Gebauer, Joachim Saas, Jochen Haag, Uwe Dietz, Masaharu Takigawa, Eckart Bartnik, Thomas Aigner Arthritis Res Ther 2005, 7:R274-R284 (11 January 2005)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

3.

1165
Accesses

Research article   Open Access Highly Accessed

Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence

Laurent G Ameye, Winnie SS Chee Arthritis Research & Therapy 2006, 8:R127 (19 July 2006)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

4.

1047
Accesses

Review   Subscription

Microbes, the gut and ankylosing spondylitis

Mary-Ellen Costello, Dirk Elewaut, Tony J Kenna, Matthew A Brown Arthritis Research & Therapy 2013, 15:214 (6 June 2013)

Abstract | Full text | PDF | PubMed

5.

1023
Accesses

Review   Subscription

Cardiovascular risk in pediatric-onset rheumatological diseases

Julie Barsalou, Timothy J Bradley, Earl D Silverman Arthritis Research & Therapy 2013, 15:212 (22 May 2013)

Abstract | Full text | PDF | PubMed

6.

906
Accesses

Research article   Open Access Highly Accessed

Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women

Daniela Di Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling, Alicja Wolk Arthritis Research & Therapy 2013, 15:R56 (22 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Smoking only a few cigarettes a day more than doubles the risk of developing rheumatoid arthritis and although this risk will lower with time after smoking cessation, it can remain elevated 15 years later.

7.

892
Accesses

Research article   Open Access

Early systemic sclerosis: marker autoantibodies and videocapillaroscopy patterns are each associated with distinct clinical, functional and cellular activation markers

Gabriele Valentini, Antonella Marcoccia, Giovanna Cuomo, Serena Vettori, Michele Iudici, Francesco Bondanini, Carlo Santoriello, Aldo Ciani, Domenico Cozzolino, Giovanni Maria De Matteis, Salvatore Cappabianca, Filiberto Vitelli, Alberto Spano Arthritis Research & Therapy 2013, 15:R63 (29 May 2013)

Abstract | Provisional PDF | PubMed

8.

860
Accesses

Review   Free Highly Accessed

Mechanisms of B cell autoimmunity in SLE

Thomas Dörner, Claudia Giesecke, Peter E Lipsky Arthritis Research & Therapy 2011, 13:243 (27 October 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

9.

826
Accesses

Research article   Open Access

Catabolic and anabolic periarticular bone changes in patients with rheumatoid arthritis: a computed tomography study on the role of age, disease duration and bone markers

Sophie Aschenberg, Stephanie Finzel, Sarah Schmidt, Sebastian Kraus, Klaus Engelke, Matthias Englbrecht, Juergen Rech, Georg Schett Arthritis Research & Therapy 2013, 15:R62 (27 May 2013)

Abstract | Provisional PDF | PubMed

10.

803
Accesses

Review   Free Highly Accessed

IL-10-producing regulatory B cells (B10 cells) in autoimmune disease

Ioannis Kalampokis, Ayumi Yoshizaki, Thomas F Tedder Arthritis Research & Therapy 2013, 15(Suppl 1):S1 (11 February 2013)

Abstract | Full text | PDF | PubMed

11.

800
Accesses

Review   Free Highly Accessed

Degeneration of the intervertebral disc

Jill PG Urban, Sally Roberts Arthritis Res Ther 2003, 5:120-130 (11 March 2003)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment

12.

775
Accesses

Research article   Open Access Highly Accessed

A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee

Krishanu Sengupta, Krishnaraju V Alluri, Andey Satish, Simanchala Mishra, Trimurtulu Golakoti, Kadainti VS Sarma, Dipak Dey, Siba P Raychaudhuri Arthritis Research & Therapy 2008, 10:R85 (30 July 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 |  Editor’s summary

An enriched extract of the Indian frankincense herb, Boswellia serrata reduced pain and improved the physical function of osteoarthritis patients, in a double blind, randomized, placebo controlled trial.

13.

747
Accesses

Editorial   Free Highly Accessed

Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation?

Peter LEM van Lent, Wim B van den Berg Arthritis Research & Therapy 2013, 15:112 (20 March 2013)

Abstract | Full text | PDF | PubMed

14.

747
Accesses

Research article   Open Access

A genetic role for macrophage migration inhibitory factor (MIF) in Adult-onset Still's disease

Fang-Fang Wang, Xin-Fang Huang, Nan Shen, Lin Leng, Richard Bucala, Shun-Le Chen, Liang-Jing Lu Arthritis Research & Therapy 2013, 15:R65 (30 May 2013)

Abstract | Provisional PDF | PubMed

15.

745
Accesses

Letter   Free

Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro'

Jing Ma, Ang Li, Shu Zhu, Xiao-Rui Cao, Guo-Xian Pei Arthritis Research & Therapy 2013, 15:408 (24 May 2013)

Abstract | Full text | PDF | PubMed

16.

736
Accesses

Research article   Open Access

Transient anabolic effects accompany epidermal growth factor receptor signal activation in articular cartilage in vivo

John B Shepard, Jae-Wook Jeong, Nita J Maihle, Sean O'Brien, Caroline N Dealy Arthritis Research & Therapy 2013, 15:R60 (25 May 2013)

Abstract | Provisional PDF | PubMed

17.

732
Accesses

Research article   Open Access

Treatment of Muckle-Wells syndrome: analysis of two IL-1-blocking regimens

Jasmin B Kuemmerle-Deschner, Helmut Wittkowski, Pascal N Tyrrell, Ina Koetter, Peter Lohse, Katharina Ummenhofer, Fabian Rees, Sandra Hansmann, Assen Koitschev, Christoph Deuter, Anja Bialkowski, Dirk Foell, Susanne M Benseler Arthritis Research & Therapy 2013, 15:R64 (29 May 2013)

Abstract | Provisional PDF | PubMed

18.

724
Accesses

Research article   Open Access Highly Accessed

Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment

Eva Klingberg, Mattias Lorentzon, Dan Mellström, Mats Geijer, Jan Göthlin, Elisabet Hilme, Martin Hedberg, Hans Carlsten, Helena Forsblad-d'Elia Arthritis Research & Therapy 2012, 14:R108 (8 May 2012)

Abstract | Full text | PDF | PubMed

19.

702
Accesses

Review   Free Highly Accessed

Gout. Novel therapies for treatment of gout and hyperuricemia

Robert Terkeltaub Arthritis Research & Therapy 2009, 11:236 (23 July 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

689
Accesses

Research article   Open Access Highly Accessed

Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism

Edwin SL Chan, Hailing Liu, Patricia Fernandez, Alex Luna, Miguel Perez-Aso, Andreea M Bujor, Maria Trojanowska, Bruce N Cronstein Arthritis Research & Therapy 2013, 15:R58 (11 May 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.

21.

690
Accesses

Research article   Open Access

IgG subclass antibodies to human and bacterial HSP60 are not associated with disease activity and progression over time in axial spondyloarthritis

Thomas G Carlsen, Astrid Hjelholt, Anne G Jurik, Berit Schiøttz-Christensen, Anna Zejden, Gunna Christiansen, Bent Deleuran, Svend Birkelund Arthritis Research & Therapy 2013, 15:R61 (25 May 2013)

Abstract | Provisional PDF | PubMed

22.

636
Accesses

Review   Free Highly Accessed

Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases

Sherine E Gabriel, Kaleb Michaud Arthritis Research & Therapy 2009, 11:229 (19 May 2009)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

23.

617
Accesses

Review   Subscription

What are the immunological consequences of long-term use of biological therapies for juvenile idiopathic arthritis?

Joost F Swart, Sytze de Roock, Nico M Wulffraat Arthritis Research & Therapy 2013, 15:213 (24 May 2013)

Abstract | Full text | PDF | PubMed

24.

604
Accesses

Research article   Open Access Highly Accessed

A novel in vitro bovine cartilage punch model for assessing the regeneration of focal cartilage defects with biocompatible bacterial nanocellulose

David Pretzel, Stefanie Linss, Hannes Ahrem, Michaela Endres, Christian Kaps, Dieter Klemm, Raimund W. Kinne Arthritis Research & Therapy 2013, 15:R59 (14 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

In vitro bovine cartilage punch model is a novel tool developed to evaluate potential bio-materials for use in cartilage regeneration and repair.

25.

601
Accesses

Review   Free

Complement and systemic lupus erythematosus

Mark J Walport Arthritis Res 2002, 4(Suppl 3):S279-S293 (9 May 2002)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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