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	1. 4431 Accesses	Research article Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women Daniela Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling, Alicja Wolk Arthritis Research & Therapy 2013, 15:R56 (22 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Smoking only a few cigarettes a day more than doubles the risk of developing rheumatoid arthritis and although this risk will lower with time after smoking cessation, it can remain elevated 15 years later.
	2. 2145 Accesses	Research article Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis Gurkirpal Singh, Olivia Wu, Peter Langhorne, Rajan Madhok Arthritis Research & Therapy 2006, 8:R153 (22 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary NSAIDs have been shown to be associated with an increased risk of acute myocardial infarctions, suggesting they should be used with caution in those with risk factors for cardiovascular disease.
	3. 1677 Accesses	Research article Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion Ami A Shah, Elena Schiopu, Laura K Hummers, Michael Wade, Kristine Phillips, Cynthia Anderson, Robert Wise, Francesco Boin, James R Seibold, Fredrick Wigley, Kristan D Rollins Arthritis Research & Therapy 2013, 15:R54 (18 April 2013) Abstract \| Provisional PDF \| PubMed
	4. 1613 Accesses	Research article Repression of anti-proliferative factor Tob1 in osteoarthritic cartilage Mathias Gebauer, Joachim Saas, Jochen Haag, Uwe Dietz, Masaharu Takigawa, Eckart Bartnik, Thomas Aigner Arthritis Res Ther 2005, 7:R274-R284 (11 January 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	5. 1316 Accesses	Review Mechanisms of B cell autoimmunity in SLE Thomas Dörner, Claudia Giesecke, Peter E Lipsky Arthritis Research & Therapy 2011, 13:243 (27 October 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	6. 1262 Accesses	Editorial Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation? Peter LEM van Lent, Wim B van den Berg Arthritis Research & Therapy 2013, 15:112 (20 March 2013) Abstract \| Full text \| PDF \| PubMed
	7. 1022 Accesses	Research article Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence Laurent G Ameye, Winnie SS Chee Arthritis Research & Therapy 2006, 8:R127 (19 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	8. 997 Accesses	Review The inflammatory process of gout and its treatment Bruce N Cronstein, Robert Terkeltaub Arthritis Research & Therapy 2006, 8(Suppl 1):S3 (12 April 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	9. 990 Accesses	Editorial A complicated liaison: IL-33 and IL-33R in arthritis pathogenesis Thomas Kamradt, Sebastian Drube Arthritis Research & Therapy 2013, 15:115 (2 May 2013) Abstract \| Full text \| PDF \| PubMed
	10. 928 Accesses	Review IL-10-producing regulatory B cells (B10 cells) in autoimmune disease Ioannis Kalampokis, Ayumi Yoshizaki, Thomas F Tedder Arthritis Research & Therapy 2013, 15(Suppl 1):S1 (11 February 2013) Abstract \| Full text \| PDF \| PubMed
	11. 883 Accesses	Research article Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFbeta1) gene in knee and hip osteoarthritis Stella G Muthuri, Sally Doherty, Weiya Zhang, Rose A Maciewicz, Kenneth Muir, Michael Doherty Arthritis Research & Therapy 2013, 15:R52 (18 April 2013) Abstract \| Provisional PDF \| PubMed
	12. 882 Accesses	Research article Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis Jerome Avouac, Maeva Vallucci, Vanessa Smith, Patricia Senet, Barbara Ruiz, Alberto Sulli, Carmen Pizzorni, Camille Frances, Gilles Chiocchia, Maurizio Cutolo, Yannick Allanore Arthritis Research & Therapy 2013, 15:R55 (19 April 2013) Abstract \| Provisional PDF \| PubMed
	13. 877 Accesses	Research article Anti-inflammatory properties of a dual PPARgamma/alpha agonist muraglitazar in in vitro and in vivo models Erja-Leena Paukkeri, Tiina Leppanen, Mira Lindholm, Mun Fei Yam, Mohd. Zaini Asmawi, Anne Kolmonen, Paula H Aulaskari, Eeva Moilanen Arthritis Research & Therapy 2013, 15:R51 (17 April 2013) Abstract \| Provisional PDF \| PubMed
	14. 873 Accesses	Review Early diagnosis to enable early treatment of pre-osteoarthritis Constance R Chu, Ashley A Williams, Christian H Coyle, Megan E Bowers Arthritis Research & Therapy 2012, 14:212 (7 June 2012) Abstract \| Full text \| PDF \| PubMed
	15. 837 Accesses	Research article A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin^®for treatment of osteoarthritis of the knee Krishanu Sengupta, Krishnaraju V Alluri, Andey Satish, Simanchala Mishra, Trimurtulu Golakoti, Kadainti VS Sarma, Dipak Dey, Siba P Raychaudhuri Arthritis Research & Therapy 2008, 10:R85 (30 July 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary An enriched extract of the Indian frankincense herb, Boswellia serrata reduced pain and improved the physical function of osteoarthritis patients, in a double blind, randomized, placebo controlled trial.
	16. 816 Accesses	Research article Association between alcohol consumption and symptom severity and quality of life in patients with fibromyalgia Chul H Kim, Ann Vincent, Daniel J Clauw, Connie A Luedtke, Jeffrey M Thompson, Terry D Schneekloth, Terry H Oh Arthritis Research & Therapy 2013, 15:R42 (15 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Low to moderate alcohol consumption lessens symptom severity and betters quality of life for fibromyalgia patients when compared to no alcohol consumption.
	17. 770 Accesses	Research article MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc Anshu Rastogi, Hyunchul Kim, Julianne D Twomey, Adam H Hsieh Arthritis Research & Therapy 2013, 15:R57 (27 April 2013) Abstract \| Provisional PDF \| PubMed
	18. 763 Accesses	Review Platelet-rich plasma therapy - future or trend? Robinder S Dhillon, Edward M Schwarz, Michael D Maloney Arthritis Research & Therapy 2012, 14:219 (8 August 2012) Abstract \| Full text \| PDF \| PubMed
	19. 726 Accesses	Research article Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism Edwin SL Chan, Hailing Liu, Patricia Fernandez, Alex Luna, Miguel Perez-Aso, Andreea M Bujor, Maria Trojanowska, Bruce N Cronstein Arthritis Research & Therapy 2013, 15:R58 (11 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.
	20. 720 Accesses	Research article Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment Eva Klingberg, Mattias Lorentzon, Dan Mellström, Mats Geijer, Jan Göthlin, Elisabet Hilme, Martin Hedberg, Hans Carlsten, Helena Forsblad-d'Elia Arthritis Research & Therapy 2012, 14:R108 (8 May 2012) Abstract \| Full text \| PDF \| PubMed
	21. 709 Accesses	Review Degeneration of the intervertebral disc Jill PG Urban, Sally Roberts Arthritis Res Ther 2003, 5:120-130 (11 March 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	22. 696 Accesses	Research article The Revised Fibromyalgia Impact Questionnaire (FIQR): validation and psychometric properties Robert M Bennett, Ronald Friend, Kim D Jones, Rachel Ward, Bobby K Han, Rebecca L Ross Arthritis Research & Therapy 2009, 11:R120 (10 August 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	23. 697 Accesses	Research article Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes Chih-Chang Yeh, Shun-Fu Chang, Ting-Ying Huang, Hsin-I Chang, Hsing-Chun Kuo, Yi-Chien Wu, Ching-Hsiang Hsieh, Chung-Sheng Shi, Cheng-Nan Chen Arthritis Research & Therapy 2013, 15:R53 (18 April 2013) Abstract \| Provisional PDF \| PubMed
	24. 692 Accesses	Review Complement and systemic lupus erythematosus Mark J Walport Arthritis Res 2002, 4(Suppl 3):S279-S293 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	25. 689 Accesses	Research article A pilot study of IL-1 inhibition by anakinra in acute gout Alexander So, Thibaut De Smedt, Sylvie Revaz, Jürg Tschopp Arthritis Research & Therapy 2007, 9:R28 (12 March 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In a pilot study on 10 patients with gouty arthritis, IL-1 blockade with anakinra gave rapid relief of inflammatory symptoms where standard treatments had failed or were not tolerated.
	26. 687 Accesses	Research article RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis Maria J Martínez-Calatrava, Ivan Prieto-Potín, Jorge A Roman-Blas, Lidia Tardio, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2012, 14:R149 (18 June 2012) Abstract \| Full text \| PDF \| PubMed
	27. 649 Accesses	Review Common variable immunodeficiency - an update Ulrich Salzer, Klaus Warnatz, Hans Peter Arthritis Research & Therapy 2012, 14:223 (24 September 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	28. 642 Accesses	Research article Rpp25 is a major target of autoantibodies to the Th/To complex as measured by a novel chemiluminescent assay Michael Mahler, Cristina Gascon, Sima Patel, Angela Ceribelli, Marvin J Fritzler, Andreas Swart, Edward KL Chan, Minoru Satoh Arthritis Research & Therapy 2013, 15:R50 (12 April 2013) Abstract \| Full text \| PDF \| PubMed
	29. 617 Accesses	Review Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases Sherine E Gabriel, Kaleb Michaud Arthritis Research & Therapy 2009, 11:229 (19 May 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	30. 617 Accesses	Editorial Kidney disease in lupus is not always 'lupus nephritis' Hans-Joachim Anders, Jan J Weening Arthritis Research & Therapy 2013, 15:108 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
	31. 615 Accesses	Review microRNA-mediated regulation of innate immune response in rheumatic diseases Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen, Yihong Yao Arthritis Research & Therapy 2013, 15:210 (9 April 2013) Abstract \| Full text \| PDF \| PubMed
	32. 596 Accesses	Review Epidemiology and genetics of rheumatoid arthritis Alan J Silman, Jacqueline E Pearson Arthritis Res 2002, 4(Suppl 3):S265-S272 (9 May 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	33. 588 Accesses	Review Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: mechanisms of action Larry W Moreland Arthritis Res Ther 2003, 5:54-67 (14 January 2003) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	34. 577 Accesses	Commentary What can rheumatologists learn from translational cancer therapy? Jonathan P Sherlock, Andrew D Filer, John D Isaacs, Christopher D Buckley Arthritis Research & Therapy 2013, 15:114 (1 May 2013) Abstract \| Full text \| PDF \| PubMed
	35. 575 Accesses	Review Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo Stadt, Stephan Ehl Arthritis Research & Therapy 2012, 14:213 (8 June 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	36. 572 Accesses	Review Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases? Udo Oppermann Arthritis Research & Therapy 2013, 15:209 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
	37. 569 Accesses	Review Interstitial lung disease in connective tissue diseases: evolving concepts of pathogenesis and management Flavia V Castelino, John Varga Arthritis Research & Therapy 2010, 12:213 (23 August 2010) Abstract \| Full text \| PDF \| PubMed
	38. 563 Accesses	Primary research Monoarticular antigen-induced arthritis leads to pronounced bilateral upregulation of the expression of neurokinin 1 and bradykinin 2 receptors in dorsal root ganglion neurons of rats Gisela von Banchet, Peter K Petrow, Rolf Bräuer, Hans-Georg Schaible Arthritis Res 2000, 2:424-427 (3 August 2000) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	39. 554 Accesses	Review Interleukin-6 and chronic inflammation Cem Gabay Arthritis Research & Therapy 2006, 8(Suppl 2):S3 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	40. 554 Accesses	Editorial Cardiovascular risk management in rheumatoid arthritis: are we still waiting for the first step? Mike JL Peters, Michael T Nurmohamed Arthritis Research & Therapy 2013, 15:111 (19 March 2013) Abstract \| Full text \| PDF \| PubMed
	41. 545 Accesses	Review B-cell targeted therapeutics in clinical development Stephan Blüml, Kathleen McKeever, Rachel Ettinger, Josef Smolen, Ronald Herbst Arthritis Research & Therapy 2013, 15(Suppl 1):S4 (4 April 2013) Abstract \| Full text \| PDF \| PubMed
	42. 523 Accesses	Review Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms? Sarah L Tansley, Neil J McHugh, Lucy R Wedderburn Arthritis Research & Therapy 2013, 15:211 (8 April 2013) Abstract \| Full text \| PDF \| PubMed
	43. 520 Accesses	Research article Vitamin D deficiency in undifferentiated connective tissue disease Eva Zold, Peter Szodoray, Janos Gaal, János Kappelmayer, Laszlo Csathy, Edit Gyimesi, Margit Zeher, Gyula Szegedi, Edit Bodolay Arthritis Research & Therapy 2008, 10:R123 (18 October 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 \| Editor’s summary A study of 161 patients with undifferentiated connective tissue disease suggests that vitamin D deficiency may be associated with the disease progressing into well-defined connective tissue diseases such as rheumatoid arthritis.
	44. 518 Accesses	Research article Effects of rehabilitative interventions on pain, function and physical impairments in people with hand osteoarthritis: a systematic review Liuzhen Ye, Leonid Kalichman, Alicia Spittle, Fiona Dobson, Kim Bennell Arthritis Research & Therapy 2011, 13:R28 (18 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Rehabilitative interventions such as exercise, splints, laser therapy and massage can improve pain, hand function, grip strength and range of motion in individuals with hand osteoarthritis.
	45. 511 Accesses	Research article Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials Winfried Häuser, Petra Klose, Jost Langhorst, Babak Moradi, Mario Steinbach, Marcus Schiltenwolf, Angela Busch Arthritis Research & Therapy 2010, 12:R79 (10 May 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	46. 511 Accesses	Review Osteoarthritis associated with estrogen deficiency Jorge A Roman-Blas, Santos Castañeda, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2009, 11:241 (21 September 2009) Abstract \| Full text \| PDF \| PubMed
	47. 494 Accesses	Research article Possible rheumatoid arthritis subtypes in terms of rheumatoid factor, depression, diagnostic delay and emotional expression: an exploratory case-control study Taavi Tillmann, Rajeev Krishnadas, Jonathan Cavanagh, KV Petrides Arthritis Research & Therapy 2013, 15:R45 (21 March 2013) Abstract \| Full text \| PDF \| PubMed
	48. 491 Accesses	Research article The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus Margareta Lantow, Ramya Sivakumar, Leilani Zeumer, Clive Wasserfall, Ying-Yi Zheng, Mark A Atkinson, Laurence Morel Arthritis Research & Therapy 2013, 15:R49 (8 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary B6.Sle2c2 mice are resistant to lupus due to a mutation in the granulocyte colony stimulating factor pathway, suggesting autoantibody production is inhibited by reduced neutrophil activation.
	49. 488 Accesses	Review An update on the hyper-IgE syndromes Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher Arthritis Research & Therapy 2012, 14:228 (30 November 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	50. 486 Accesses	Review Cellular and molecular pathogenesis of systemic lupus erythematosus: lessons from animal models Simanta Pathak, Chandra Mohan Arthritis Research & Therapy 2011, 13:241 (30 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	51. 470 Accesses	Correction Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthritis chondrocytes in vitro Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2013, 15:407 (10 May 2013) Abstract \| Full text \| PDF \| PubMed
	52. 469 Accesses	Research article Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity Pedro Recarte-Pelz, Dolors Tàssies, Gerard Espinosa, Begoña Hurtado, Núria Sala, Ricard Cervera, Joan Reverter, Pablo de Frutos Arthritis Research & Therapy 2013, 15:R41 (12 March 2013) Abstract \| Full text \| PDF \| PubMed
	53. 463 Accesses	Review Mucocutaneous candidiasis: the IL-17 pathway and implications for targeted immunotherapy Anna R Huppler, Shrinivas Bishu, Sarah L Gaffen Arthritis Research & Therapy 2012, 14:217 (23 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	54. 455 Accesses	Research article Gluten-free vegan diet induces decreased LDL and oxidized LDL levels and raised atheroprotective natural antibodies against phosphorylcholine in patients with rheumatoid arthritis: a randomized study Ann-Charlotte Elkan, Beatrice Sjöberg, Björn Kolsrud, Bo Ringertz, Ingiäld Hafström, Johan Frostegård Arthritis Research & Therapy 2008, 10:R34 (18 March 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A gluten-free vegan diet induces potentially atheroprotective and anti-inflammatory changes in rheumatoid arthritis patients, including reduced low density lipoprotein (LDL) and oxidated LDL levels and raised natural antibodies against phosphorylcholine.
	55. 453 Accesses	Research article Antibodies of IgG, IgA and IgM isotypes against cyclic citrullinated peptide precede the development of rheumatoid arthritis Heidi Kokkonen, Mohammed Mullazehi, Ewa Berglin, Göran Hallmans, Göran Wadell, Johan Rönnelid, Solbritt Rantapää-Dahlqvist Arthritis Research & Therapy 2011, 13:R13 (3 February 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	56. 450 Accesses	Research article Mechanisms of quadriceps muscle weakness in knee joint osteoarthritis: the effects of prolonged vibration on torque and muscle activation in osteoarthritic and healthy control subjects David A Rice, Peter J McNair, Gwyn N Lewis Arthritis Research & Therapy 2011, 13:R151 (20 September 2011) Abstract \| Full text \| PDF \| PubMed
	57. 444 Accesses	Review Adult mesenchymal stem cells and cell-based tissue engineering Rocky S Tuan, Genevieve Boland, Richard Tuli Arthritis Res Ther 2003, 5:32-45 (11 December 2002) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	58. 437 Accesses	Research article The spectrum of renal thrombotic microangiopathy in lupus nephritis Di Song, Li-hua Wu, Feng-mei Wang, Xiao-wei Yang, Di Zhu, Min Chen, Feng Yu, Gang Liu, Ming-hui Zhao Arthritis Research & Therapy 2013, 15:R12 (15 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	59. 434 Accesses	Editorial Autoimmunity induced by human cytomegalovirus in patients with systemic lupus erythematosus Cecilia Söderberg-Nauclér Arthritis Research & Therapy 2012, 14:101 (23 January 2012) Abstract \| Full text \| PDF \| PubMed
	60. 432 Accesses	Review A concise history of gout and hyperuricemia and their treatment George Nuki, Peter A Simkin Arthritis Research & Therapy 2006, 8(Suppl 1):S1 (12 April 2006) Abstract \| Full text \| PDF \| PubMed
	61. 423 Accesses	Review Pathogenesis of tendinopathies: inflammation or degeneration? Michele Abate, Karin Gravare Silbernagel, Carl Siljeholm, Angelo Di Iorio, Daniele De Amicis, Vincenzo Salini, Suzanne Werner, Roberto Paganelli Arthritis Research & Therapy 2009, 11:235 (30 June 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	62. 421 Accesses	Review B-cell subpopulations in humans and their differential susceptibility to depletion with anti-CD20 monoclonal antibodies Maria J Leandro Arthritis Research & Therapy 2013, 15(Suppl 1):S3 (25 March 2013) Abstract \| Full text \| PDF \| PubMed
	63. 420 Accesses	Letter Colchicine in acute gouty arthritis: the optimum dose? George I Varughese, Abraham I Varghese Arthritis Research & Therapy 2006, 8:405 (19 September 2006) Abstract \| Full text \| PDF \| PubMed
	64. 416 Accesses	Research article Clinical features of symptomatic patellofemoral joint osteoarthritis George Peat, Rachel C Duncan, Laurence RJ Wood, Elaine Thomas, Sara Muller Arthritis Research & Therapy 2012, 14:R63 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
	65. 415 Accesses	Research article Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study Antonio Naranjo, Tuulikki Sokka, Miguel A Descalzo, Jaime Calvo-Alén, Kim Hørslev-Petersen, Reijo K Luukkainen, Bernard Combe, Gerd R Burmester, Joe Devlin, Gianfranco Ferraccioli, Alessia Morelli, Monique Hoekstra, Maria Majdan, Stefan Sadkiewicz, Miguel Belmonte, Ann-Carin Holmqvist, Ernest Choy, Recep Tunc, Aleksander Dimic, Martin Bergman, Sergio Toloza, Theodore Pincus, the QUEST-RA Group Arthritis Research & Therapy 2008, 10:R30 (6 March 2008) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Treating rheumatoid arthritis with disease-modifying anti-rheumatic drugs, such as methotrexate, reduces the risk of heart attacks and strokes, data from a study of 4,363 patients across 15 countries shows.
	66. 403 Accesses	Research article Anti-cyclic citrullinated peptide antibody titer predicts time to rheumatoid arthritis onset in patients with undifferentiated arthritis: results from a 2-year prospective study Nicola Bizzaro, Elena Bartoloni, Gabriella Morozzi, Stefania Manganelli, Valeria Riccieri, Paola Sabatini, Matteo Filippini, Marilina Tampoia, Antonella Afeltra, Giandomenico Sebastiani, Claudia Alpini, Vittorio Bini, Onelia Bistoni, Alessia Alunno, Roberto Gerli, the Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni (FIRMA Group) Arthritis Research & Therapy 2013, 15:R16 (22 January 2013) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	67. 398 Accesses	Research article Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Marcelo H Petri, Minoru Satoh, Beatriz T Martin-Marquez, Raul Vargas-Ramírez, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Gonzalez, Lilia Andrade-Ortega, Olga Vera-Lastra, Mario Salazar-Páramo, Rosa E Prieto-Parra, Laura Gonzalez-Lopez, Jorge I Gamez-Nava, Hermes U Ramírez-Sánchez, Jason YF Chan, Steven J Ross, Edward KL Chan, Mónica Mercado Arthritis Research & Therapy 2013, 15:R48 (4 April 2013) Abstract \| Provisional PDF \| PubMed
	68. 396 Accesses	Research article MMP13 is a critical target gene during the progression of osteoarthritis Meina Wang, Erik R Sampson, Hongting Jin, Jia Li, Qiao H Ke, Hee-Jeong Im, Di Chen Arthritis Research & Therapy 2013, 15:R5 (8 January 2013) Abstract \| Full text \| PDF \| PubMed
	69. 393 Accesses	Review Mesenchymal stromal cells. Biology of adult mesenchymal stem cells: regulation of niche, self-renewal and differentiation Catherine M Kolf, Elizabeth Cho, Rocky S Tuan Arthritis Research & Therapy 2007, 9:204 (19 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	70. 395 Accesses	Research article Distinguishing fibromyalgia from rheumatoid arthritis and systemic lupus in clinical questionnaires: an analysis of the revised Fibromyalgia Impact Questionnaire (FIQR) and its variant, the Symptom Impact Questionnaire (SIQR), along with pain locations Ronald Friend, Robert M Bennett Arthritis Research & Therapy 2011, 13:R58 (8 April 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A combination of 2 questions from the symptom impact questionnaire plus pain in four locations identified the correct diagnosis in 97% of subjects with fibromyalgia, rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).
	71. 390 Accesses	Review The association between rheumatoid arthritis and periodontal disease Jacqueline Detert, Nicole Pischon, Gerd R Burmester, Frank Buttgereit Arthritis Research & Therapy 2010, 12:218 (22 October 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	72. 384 Accesses	Editorial The butterfly rash of lupus: An example of aposematism? David S Pisetsky Arthritis Research & Therapy 2013, 15:106 (19 February 2013) Abstract \| Full text \| PDF \| PubMed
	73. 382 Accesses	Review Developments in lupus 2006 Arne Hansen, Falk Hiepe, Thomas Dörner Arthritis Research & Therapy 2007, 9:215 (11 July 2007) Abstract \| Full text \| PDF \| PubMed
	74. 379 Accesses	Research article CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts Chun-Han Hou, Chih-Hsin Tang, Chin-Jung Hsu, Sheng-Mon Hou, Ju-Fang Liu Arthritis Research & Therapy 2013, 15:R19 (23 January 2013) Abstract \| Full text \| PDF \| PubMed
	75. 379 Accesses	Review Gout. Novel therapies for treatment of gout and hyperuricemia Robert Terkeltaub Arthritis Research & Therapy 2009, 11:236 (23 July 2009) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	76. 377 Accesses	Research article Evaluation of the novel folate receptor ligand [¹⁸F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis Yoony YJ Gent, Karin Weijers, Carla FM Molthoff, Albert D Windhorst, Marc C Huisman, Desirée EC Smith, Sumith A Kularatne, Gerrit Jansen, Philip S Low, Adriaan A Lammertsma, Conny J van der Laken Arthritis Research & Therapy 2013, 15:R37 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
	77. 376 Accesses	Review Treatment targets in systemic lupus erythematosus: biology and clinical perspective Valentin Marian, Jennifer H Anolik Arthritis Research & Therapy 2012, 14(Suppl 4):S3 (30 November 2012) Abstract \| Full text \| PDF \| PubMed
	78. 368 Accesses	Research article Monitoring cartilage loss in the hands and wrists in rheumatoid arthritis with magnetic resonance imaging in a multi-center clinical trial: IMPRESS (NCT00425932) Charles G Peterfy, Ewa Olech, Julie C DiCarlo, Joan T Merrill, Peter J Countryman, Norman B Gaylis Arthritis Research & Therapy 2013, 15:R44 (20 March 2013) Abstract \| Provisional PDF \| PubMed
	79. 367 Accesses	Research article A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis Rui Liu, Qian Wu, Dinglei Su, Nan Che, Haifeng Chen, Linyu Geng, Jinyun Chen, Wanjun Chen, Xia Li, Lingyun Sun Arthritis Research & Therapy 2012, 14:R255 (23 November 2012) Abstract \| Full text \| PDF \| PubMed
	80. 365 Accesses	Review Recent advances in shoulder research Megan L Killian, Leonardo Cavinatto, Leesa M Galatz, Stavros Thomopoulos Arthritis Research & Therapy 2012, 14:214 (15 June 2012) Abstract \| Full text \| PDF \| PubMed
	81. 365 Accesses	Review Perspectives on epigenetic-based immune intervention for rheumatic diseases Steven G Gray Arthritis Research & Therapy 2013, 15:207 (14 March 2013) Abstract \| Full text \| PDF \| PubMed
	82. 362 Accesses	Review B-cell depletion in SLE: clinical and trial experience with rituximab and ocrelizumab and implications for study design Venkat Reddy, David Jayne, David Close, David Isenberg Arthritis Research & Therapy 2013, 15(Suppl 1):S2 (11 February 2013) Abstract \| Full text \| PDF \| PubMed
	83. 363 Accesses	Review Rationale of anti-CD19 immunotherapy: an option to target autoreactive plasma cells in autoimmunity Henrik E Mei, Stefanie Schmidt, Thomas Dörner Arthritis Research & Therapy 2012, 14(Suppl 5):S1 (8 November 2012) Abstract \| Full text \| PDF \| PubMed
	84. 361 Accesses	Research article The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial Michael A Becker, H Ralph Schumacher, Luis R Espinoza, Alvin F Wells, Patricia MacDonald, Eric Lloyd, Christopher Lademacher Arthritis Research & Therapy 2010, 12:R63 (6 April 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	85. 358 Accesses	Review Articular cartilage and changes in Arthritis: Cell biology of osteoarthritis Linda J Sandell, Thomas Aigner Arthritis Res 2001, 3:107-113 (22 January 2001) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	86. 358 Accesses	Review Fish oil: what the prescriber needs to know Leslie G Cleland, Michael J James, Susanna M Proudman Arthritis Research & Therapy 2006, 8:202 (21 December 2005) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	87. 354 Accesses	Review Mechanisms of tissue injury in lupus nephritis Tamara K Nowling, Gary S Gilkeson Arthritis Research & Therapy 2011, 13:250 (21 December 2011) Abstract \| Full text \| PDF \| PubMed
	88. 353 Accesses	Research article Treatment of rheumatoid arthritis in the Medicare Current Beneficiary Survey Daniel H Solomon, Edward Yelin, Jeffrey N Katz, Bing Lu, Tamara Shaykevich, John Z Ayanian Arthritis Research & Therapy 2013, 15:R43 (18 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Medicare patients with rheumatoid arthritis are less likely to receive disease-modifying anti-rheumatic drug (DMARD) treatment if they are not seeing a rheumatologist, have a lower income, or are older.
	89. 351 Accesses	Review Anti-inflammatory and immunosuppressive drugs and reproduction Monika Østensen, Munther Khamashta, Michael Lockshin, Ann Parke, Antonio Brucato, Howard Carp, Andrea Doria, Raj Rai, Pierluigi Meroni, Irene Cetin, Ronald Derksen, Ware Branch, Mario Motta, Caroline Gordon, Guillermo Ruiz-Irastorza, Arsenio Spinillo, Deborah Friedman, Rolando Cimaz, Andrew Czeizel, Jean Piette, Ricard Cervera, Roger A Levy, Maurizio Clementi, Sara De Carolis, Michelle Petri, Yehuda Shoenfeld, David Faden, Guido Valesini, Angela Tincani Arthritis Research & Therapy 2006, 8:209 (11 May 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	90. 351 Accesses	Research article Integrated safety in tocilizumab clinical trials Michael H Schiff, Joel M Kremer, Angelika Jahreis, Emma Vernon, John D Isaacs, Ronald F van Vollenhoven Arthritis Research & Therapy 2011, 13:R141 (1 September 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	91. 351 Accesses	Research article Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies Lucas A Smolders, Björn P Meij, David Onis, Frank M Riemers, Niklas Bergknut, Richard Wubbolts, Guy CM Grinwis, Martin Houweling, Marian JA Groot Koerkamp, Dik van Leenen, Frank CP Holstege, Herman AW Hazewinkel, Laura B Creemers, Louis C Penning, Marianna A Tryfonidou Arthritis Research & Therapy 2013, 15:R23 (29 January 2013) Abstract \| Full text \| PDF \| PubMed
	92. 350 Accesses	Research article Scoring radiographic progression in ankylosing spondylitis: should we use the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) or the Radiographic Ankylosing Spondylitis Spinal Score (RASSS)? Sofia Ramiro, Astrid van Tubergen, Carmen Stolwijk, Robert Landewé, Filip van de Bosch, Maxime Dougados, Désirée van der Heijde Arthritis Research & Therapy 2013, 15:R14 (17 January 2013) Abstract \| Full text \| PDF \| PubMed
	93. 349 Accesses	Research article Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis Fiona E McCann, Andrew C Palfreeman, Melanie Andrews, Dany P Perocheau, Julia J Inglis, Peter Schafer, Marc Feldmann, Richard O Williams, Fionula M Brennan Arthritis Research & Therapy 2010, 12:R107 (2 June 2010) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	94. 347 Accesses	Review B-cell selection and the development of autoantibodies Natalia V Giltiay, Craig P Chappell, Edward A Clark Arthritis Research & Therapy 2012, 14(Suppl 4):S1 (2 November 2012) Abstract \| Full text \| PDF \| PubMed
	95. 346 Accesses	Research article A novel in vitro bovine cartilage punch model for assessing the regeneration of focal cartilage defects with biocompatible bacterial nanocellulose David Pretzel, Stefanie Linss, Hannes Ahrem, Michaela Endres, Christian Kaps, Dieter Klemm, Raimund W. Kinne Arthritis Research & Therapy 2013, 15:R59 (14 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary In vitro bovine cartilage punch model is a novel tool developed to evaluate potential bio-materials for use in cartilage regeneration and repair.
	96. 345 Accesses	Research article Exercise training in childhood-onset systemic lupus erythematosus: a controlled randomized trial Danilo ML Prado, Fabiana B Benatti, Ana L de Sá-Pinto, Ana P Hayashi, Bruno Gualano, Rosa MR Pereira, Adriana ME Sallum, Eloisa Bonfá, Clovis A Silva, Hamilton Roschel Arthritis Research & Therapy 2013, 15:R46 (26 March 2013) Abstract \| Provisional PDF \| PubMed
	97. 342 Accesses	Research article Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin? Jan L Bjersing, Malin Erlandsson, Maria I Bokarewa, Kaisa Mannerkorpi Arthritis Research & Therapy 2013, 15:R34 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
	98. 339 Accesses	Review Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy Daniel Aeberli, Georg Schett Arthritis Research & Therapy 2013, 15:208 (21 March 2013) Abstract \| Full text \| PDF \| PubMed
	99. 337 Accesses	Research article Inflammation associated anemia and ferritin as disease markers in SLE Kamala Vanarsa, Yujin Ye, Jie Han, Chun Xie, Chandra Mohan, Tianfu Wu Arthritis Research & Therapy 2012, 14:R182 (7 August 2012) Abstract \| Full text \| PDF \| PubMed
	100. 334 Accesses	Review Immunoglobulin class-switch recombination deficiencies Anne Durandy, Sven Kracker Arthritis Research & Therapy 2012, 14:218 (30 July 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central