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 Welcome to Arthritis Research & Therapy
  Translating research into clinical practice
  Editors-in-Chief: Peter E Lipsky, Bethesda, USA and Ravinder N Maini, London, UK

 
 
 
 
Research highlight: Infliximab variably regulates interferon expression    Open Access
Regulation of interferon-response gene expression levels during TNF blockade was highly variable between rheumatoid arthritis patients, with increased gene activity associated with poor clinical response to infliximab treatment.
Arthritis Research & Therapy 2010, 12:R11

Latest articles

Research article    
Regulation of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase-activating protein/5-lipoxygenase by 4-hydroxynonenal in human osteoarthritic chondrocytes
Shu-Huang Chen, Hassan Fahmi, Qin Shi, Mohamed Benderdour
Arthritis Research & Therapy 2010, 12:R21 (9 February 2010)
[Abstract] [Provisional PDF]




Research article    
Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression
Marie-Solange Mutabaruka, Mohamed Aoulad Aissa, Aline Delalandre, Martin Lavigne, Daniel Lajeunesse
Arthritis Research & Therapy 2010, 12:R20 (8 February 2010)
[Abstract] [Provisional PDF]




Editorial    
Is Phytalgic® a goldmine for osteoarthritis patients or is there something fishy about this nutraceutical? A summary of findings and risk-of-bias assessment
Robin Christensen, Henning Bliddal
Arthritis Research & Therapy 2010, 12:105 (8 February 2010)
[PDF]




Research article    
Autophagy induction and CHOP under-expression promotes survival of fibroblasts from rheumatoid arthritis patients under endoplasmic reticulum stress
Yong-Joo Shin, Song-Hee Han, Do-Sung Kim, Geum-Hwa Lee, Wan-Hee Yoo, Yong-Mo Kang, Je-Yong Choi, Yong Chul Lee, Seong Ju Park, Seul-Ki Jeong, Hyung-Tae Kim, Soo-Wan Chae, Hyun-Ja Jeong, Hyung-Ryong Kim, Han-Jung Chae
Arthritis Research & Therapy 2010, 12:R19 (1 February 2010)
[Abstract] [Provisional PDF] [PubMed] [Related articles]




Editorial    
From the item to the outcome: the promising prospects of PROMIS
Daniel Aletaha
Arthritis Research & Therapy 2010, 12:104 (1 February 2010)
[Abstract] [Full text] [PDF]




Review   
A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis
Peter M van der Kraan, Esmeralda N Blaney Davidson, Wim B van den Berg
Arthritis Research & Therapy 2010, 12:201 (29 January 2010)
[Abstract] [Full text] [PDF]




Thank you to all our reviewers in 2009

We are grateful for your help in ensuring Arthritis Research & Therapy authors receive prompt, thorough and constructive feedback on their work.


The Scientific Basis of Rheumatology: A Decade of Progress

To mark its 10th anniversary, Arthritis Research & Therapy is publishing a freely available, four-part collection of new review articles.
This special issue provides an in depth overview of the current status of basic and clinical research in rheumatology.

Complete collection free online





All articles published in supplements are fully peer reviewed.

Latest free review article   

The following article has recently become free to access:

Review 
Gout. Novel therapies for treatment of gout and hyperuricemia
Robert Terkeltaub
Arthritis Research & Therapy 2009, 11:236 (23 July 2009)
[Abstract] [Full text] [PDF] [PubMed] [Related articles]

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