Arthritis Research & Therapy

Submit a manuscript Register Contact us Follow us on Twitter

Explore journal

Advertisement

Articles

Supplements

Display/download options Articles per page: 25 | 50 | 100

Display options

Editor's summary Citation

Download options

Send
To

	All
		Research article Predictors of use of pain medications for persistent knee pain after primary Total Knee Arthroplasty: a cohort study using an institutional joint registry Jasvinder A Singh, David G Lewallen Arthritis Research & Therapy 2012, 14:R248 (16 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Patients that have had primary Total Knee Arthroplasty (TKA) are more likely to continue using pain medication if they are female, of a younger age, or suffering from depression or anxiety.
		Research article Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3 Marije Oosting, Kathrin Buffen, Subbarao RK Malireddi, Patrick Sturm, Ineke Verschueren, Marije I Koenders, Frank L van de Veerdonk, Jos WM van der Meer, Mihai G Netea, Thirumala-Devi Kanneganti, Leo AB Joosten Arthritis Research & Therapy 2012, 14:R247 (13 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary An early murine Lyme arthritis model using intra-articular injection of live B.burgdorferi demonstrates that induction of Lyme arthritis is strongly dependent on IL-1β production, suggesting IL-1 may be a future therapeutic target.
		Research article IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis Young-Mee Moon, Bo-Young Yoon, Yang-Mi Her, Hye-Joa Oh, Jae-Seon Lee, Kyoung-Woon Kim, Seon-Yeong Lee, Yun-Ju Woo, Kyung-Su Park, Sung-Hwan Park, Ho-Youn Kim, Mi-La Cho Arthritis Research & Therapy 2012, 14:R246 (13 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints Tania N Crotti, Anak ASSK Dharmapatni, Ekram Alias, Andrew CW Zannettino, Malcolm D Smith, David R Haynes Arthritis Research & Therapy 2012, 14:R245 (12 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity Atsushi Tanaka, Hiroshi Tsukamoto, Hiroki Mitoma, Chikako Kiyohara, Naoyasu Ueda, Masahiro Ayano, Shun-ichiro Ohta, Yasushi Inoue, Yojirou Arinobu, Hiroaki Niiro, Takahiko Horiuchi, Koichi Akashi Arthritis Research & Therapy 2012, 14:R244 (11 November 2012) Abstract \| Full text \| PDF \| PubMed
		Review Epigenetic contributions in the development of rheumatoid arthritis Kerstin Klein, Caroline Ospelt, Steffen Gay Arthritis Research & Therapy 2012, 14:227 (9 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus Jack Hutcheson, Kamala Vanarsa, Anna Bashmakov, Simer Grewal, Deena Sajitharan, Betty Y Chang, Joseph J Buggy, Xin J Zhou, Yong Du, Anne B Satterthwaite, Chandra Mohan Arthritis Research & Therapy 2012, 14:R243 (8 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2012, 14:R242 (7 November 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Effect of autologous platelet-rich plasma-releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study Shuji Obata, Koji Akeda, Takao Imanishi, Koichi Masuda, Won Bae, Ryo Morimoto, Yumiko Asanuma, Yuichi Kasai, Atsumasa Uchida, Akihiro Sudo Arthritis Research & Therapy 2012, 14:R241 (5 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Citrullination of fibronectin modulates synovial fibroblast behavior Miriam A Shelef, David A Bennin, Deane F Mosher, Anna Huttenlocher Arthritis Research & Therapy 2012, 14:R240 (5 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Altered behaviour of synovial fibroblasts on citrullinated fibronectin suggests interaction of synovial fibroblasts with the citrullinated matrix may play an important role in the pathophysiology of rheumatoid arthritis (RA).
		Research article Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease Sebastien Viatte, Edward Flynn, Mark Lunt, Joanne Barnes, Madeleine Singwe-Ngandeu, Sylvette Bas, Anne Barton, Cem Gabay Arthritis Research & Therapy 2012, 14:R239 (3 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model Steve Horvath, Abu NM Nazmul-Hossain, Rodney PE Pollard, Frans GM Kroese, Arjan Vissink, Cees GM Kallenberg, Fred KL Spijkervet, Hendrika Bootsma, Sara A Michie, Sven U Gorr, Ammon B Peck, Chaochao Cai, Hui Zhou, David TW Wong Arthritis Research & Therapy 2012, 14:R238 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains Tsvetelina Batsalova, Ingrid Lindh, Johan Bäcklund, Balik Dzhambazov, Rikard Holmdahl Arthritis Research & Therapy 2012, 14:R237 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia Yu Shang, Katelyn Gurley, Brock Symons, Douglas Long, Ratchakrit Srikuea, Leslie J Crofford, Charlotte A Peterson, Guoqiang Yu Arthritis Research & Therapy 2012, 14:R236 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Y27, a novel derivative of 4-hydroxyquinoline-3-formamide, prevents the development of murine systemic lupus erythematosus-like diseases in MRL/lpr autoimmune mice and BDF1 hybrid mice Zhi-Yong Xiao, Shao-Hui Chen, Jun-Ping Cheng, Wen-Xia Zhou, Yong-Xiang Zhang, Ri-Fang Yang, Liu-Hong Yun Arthritis Research & Therapy 2012, 14:R235 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice Flavia SA Pelegrino, Eugene A Volpe, Niral B Gandhi, De-Quan Li, Stephen C Pflugfelder, Cintia S de Paiva Arthritis Research & Therapy 2012, 14:R234 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Review New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis Matthew S Doyle, Emily S Collins, Oliver M FitzGerald, Stephen R Pennington Arthritis Research & Therapy 2012, 14:226 (31 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Muscle-fiber transdifferentiation in an experimental model of respiratory chain myopathy Nils Venhoff, Dirk Lebrecht, Dietmar Pfeifer, Ana C Venhoff, Emmanuel Bissé, Janbernd Kirschner, Ulrich A Walker Arthritis Research & Therapy 2012, 14:R233 (29 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Leflunomide increases the risk of silent liver fibrosis in patients with rheumatoid arthritis receiving methotrexate Sang-Won Lee, Hee-Jin Park, Beom Kim, Kwang-Hyub Han, Soo-Kon Lee, Seung Kim, Yong-Beom Park Arthritis Research & Therapy 2012, 14:R232 (29 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Cumulative dose of leflunomide correlated closely with the presence of silent liver fibrosis in rheumatoid arthritis patients treated with methotrexate.
		Research article Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes Athanassios Fragoulis, Jendrik Laufs, Susanna Müller, Ulf Soppa, Stephanie Siegl, Lucy Reiss, Mersedeh Tohidnezhad, Christian Rosen, Klaus Tenbrock, Deike Varoga, Sebastian Lippross, Thomas Pufe, Christoph Wruck Arthritis Research & Therapy 2012, 14:R220 (27 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Changes in pain catastrophizing predict later changes in fibromyalgia clinical and experimental pain report: cross-lagged panel analyses of dispositional and situational catastrophizing Claudia M Campbell, Lea McCauley, Sara C Bounds, Vani A Mathur, Lora Conn, Mpepera Simango, Robert R Edwards, Kevin R Fontaine Arthritis Research & Therapy 2012, 14:R231 (25 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Double-blind, placebo-controlled randomized trial with adalimumab for treatment of juvenile onset ankylosing spondylitis (JoAS): significant short term improvement Gerd Horneff, Sigrid Fitter, Ivan Foeldvari, Kirsten Minden, Jasmin Kuemmerle-Deschner, Nicolay Tzaribacev, Angelika Thon, Michael Borte, Gerd Ganser, Rolf Trauzeddel, Hans-Iko Huppertz Arthritis Research & Therapy 2012, 14:R230 (24 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A double-blind randomized trial found adalimumab treatment was significantly superior to placebo in the treatment of juvenile onset ankylosing spondylitis (AS), being well tolerated and highly effective.
		Research article The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy Feng Fang, Lei Liu, Yang Yang, Zenshiro Tamaki, Jun Wei, Roberta G Marangoni, Swati Bhattacharyya, Ross S Summer, Boping Ye, John Varga Arthritis Research & Therapy 2012, 14:R229 (23 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Activation of the adiponectin pathway has potent antifibrotic effects in normal and scleroderma fibroblasts, and is a potential therapeutic target to control fibrosis in scleroderma and other chronic fibrosing conditions.
		Research article Interleukin-29 modulates proinflammatory cytokine production in synovial inflammation of rheumatoid arthritis Fang Wang, Lingxiao Xu, Xiaoke Feng, Dunming Guo, Wenfeng Tan, Miaojia Zhang Arthritis Research & Therapy 2012, 14:R228 (19 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Th17 expansion in granulomatosis with polyangiitis (Wegener's): the role of disease activity, immune regulation and therapy Benjamin Wilde, Marielle Thewissen, Jan Damoiseaux, Marc Hilhorst, Pieter van Paassen, Oliver Witzke, Jan Cohen Tervaert Arthritis Research & Therapy 2012, 14:R227 (18 October 2012) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Predictors of use of pain medications for persistent knee pain after primary Total Knee Arthroplasty: a cohort study using an institutional joint registry Jasvinder A Singh, David G Lewallen Arthritis Research & Therapy 2012, 14:R248 (16 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Patients that have had primary Total Knee Arthroplasty (TKA) are more likely to continue using pain medication if they are female, of a younger age, or suffering from depression or anxiety.
		Research article Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3 Marije Oosting, Kathrin Buffen, Subbarao RK Malireddi, Patrick Sturm, Ineke Verschueren, Marije I Koenders, Frank L van de Veerdonk, Jos WM van der Meer, Mihai G Netea, Thirumala-Devi Kanneganti, Leo AB Joosten Arthritis Research & Therapy 2012, 14:R247 (13 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary An early murine Lyme arthritis model using intra-articular injection of live B.burgdorferi demonstrates that induction of Lyme arthritis is strongly dependent on IL-1β production, suggesting IL-1 may be a future therapeutic target.
		Research article IL-32 and IL-17 interact and have the potential to aggravate osteoclastogenesis in rheumatoid arthritis Young-Mee Moon, Bo-Young Yoon, Yang-Mi Her, Hye-Joa Oh, Jae-Seon Lee, Kyoung-Woon Kim, Seon-Yeong Lee, Yun-Ju Woo, Kyung-Su Park, Sung-Hwan Park, Ho-Youn Kim, Mi-La Cho Arthritis Research & Therapy 2012, 14:R246 (13 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints Tania N Crotti, Anak ASSK Dharmapatni, Ekram Alias, Andrew CW Zannettino, Malcolm D Smith, David R Haynes Arthritis Research & Therapy 2012, 14:R245 (12 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Serum progranulin levels are elevated in patients with systemic lupus erythematosus, reflecting disease activity Atsushi Tanaka, Hiroshi Tsukamoto, Hiroki Mitoma, Chikako Kiyohara, Naoyasu Ueda, Masahiro Ayano, Shun-ichiro Ohta, Yasushi Inoue, Yojirou Arinobu, Hiroaki Niiro, Takahiko Horiuchi, Koichi Akashi Arthritis Research & Therapy 2012, 14:R244 (11 November 2012) Abstract \| Full text \| PDF \| PubMed
		Review Epigenetic contributions in the development of rheumatoid arthritis Kerstin Klein, Caroline Ospelt, Steffen Gay Arthritis Research & Therapy 2012, 14:227 (9 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Modulating proximal cell signaling by targeting Btk ameliorates humoral autoimmunity and end-organ disease in murine lupus Jack Hutcheson, Kamala Vanarsa, Anna Bashmakov, Simer Grewal, Deena Sajitharan, Betty Y Chang, Joseph J Buggy, Xin J Zhou, Yong Du, Anne B Satterthwaite, Chandra Mohan Arthritis Research & Therapy 2012, 14:R243 (8 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2012, 14:R242 (7 November 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Effect of autologous platelet-rich plasma-releasate on intervertebral disc degeneration in the rabbit anular puncture model: a preclinical study Shuji Obata, Koji Akeda, Takao Imanishi, Koichi Masuda, Won Bae, Ryo Morimoto, Yumiko Asanuma, Yuichi Kasai, Atsumasa Uchida, Akihiro Sudo Arthritis Research & Therapy 2012, 14:R241 (5 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Citrullination of fibronectin modulates synovial fibroblast behavior Miriam A Shelef, David A Bennin, Deane F Mosher, Anna Huttenlocher Arthritis Research & Therapy 2012, 14:R240 (5 November 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Altered behaviour of synovial fibroblasts on citrullinated fibronectin suggests interaction of synovial fibroblasts with the citrullinated matrix may play an important role in the pathophysiology of rheumatoid arthritis (RA).
		Research article Investigation of Caucasian rheumatoid arthritis susceptibility loci in African patients with the same disease Sebastien Viatte, Edward Flynn, Mark Lunt, Joanne Barnes, Madeleine Singwe-Ngandeu, Sylvette Bas, Anne Barton, Cem Gabay Arthritis Research & Therapy 2012, 14:R239 (3 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model Steve Horvath, Abu NM Nazmul-Hossain, Rodney PE Pollard, Frans GM Kroese, Arjan Vissink, Cees GM Kallenberg, Fred KL Spijkervet, Hendrika Bootsma, Sara A Michie, Sven U Gorr, Ammon B Peck, Chaochao Cai, Hui Zhou, David TW Wong Arthritis Research & Therapy 2012, 14:R238 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Comparative analysis of collagen type II-specific immune responses during development of collagen-induced arthritis in two B10 mouse strains Tsvetelina Batsalova, Ingrid Lindh, Johan Bäcklund, Balik Dzhambazov, Rikard Holmdahl Arthritis Research & Therapy 2012, 14:R237 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Noninvasive optical characterization of muscle blood flow, oxygenation, and metabolism in women with fibromyalgia Yu Shang, Katelyn Gurley, Brock Symons, Douglas Long, Ratchakrit Srikuea, Leslie J Crofford, Charlotte A Peterson, Guoqiang Yu Arthritis Research & Therapy 2012, 14:R236 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Y27, a novel derivative of 4-hydroxyquinoline-3-formamide, prevents the development of murine systemic lupus erythematosus-like diseases in MRL/lpr autoimmune mice and BDF1 hybrid mice Zhi-Yong Xiao, Shao-Hui Chen, Jun-Ping Cheng, Wen-Xia Zhou, Yong-Xiang Zhang, Ri-Fang Yang, Liu-Hong Yun Arthritis Research & Therapy 2012, 14:R235 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Deletion of interferon-γ delays onset and severity of dacryoadenitis in CD25KO mice Flavia SA Pelegrino, Eugene A Volpe, Niral B Gandhi, De-Quan Li, Stephen C Pflugfelder, Cintia S de Paiva Arthritis Research & Therapy 2012, 14:R234 (1 November 2012) Abstract \| Full text \| PDF \| PubMed
		Review New insight into the functions of the interleukin-17 receptor adaptor protein Act1 in psoriatic arthritis Matthew S Doyle, Emily S Collins, Oliver M FitzGerald, Stephen R Pennington Arthritis Research & Therapy 2012, 14:226 (31 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Muscle-fiber transdifferentiation in an experimental model of respiratory chain myopathy Nils Venhoff, Dirk Lebrecht, Dietmar Pfeifer, Ana C Venhoff, Emmanuel Bissé, Janbernd Kirschner, Ulrich A Walker Arthritis Research & Therapy 2012, 14:R233 (29 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Leflunomide increases the risk of silent liver fibrosis in patients with rheumatoid arthritis receiving methotrexate Sang-Won Lee, Hee-Jin Park, Beom Kim, Kwang-Hyub Han, Soo-Kon Lee, Seung Kim, Yong-Beom Park Arthritis Research & Therapy 2012, 14:R232 (29 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Cumulative dose of leflunomide correlated closely with the presence of silent liver fibrosis in rheumatoid arthritis patients treated with methotrexate.
		Research article Sulforaphane has opposing effects on TNF-alpha stimulated and unstimulated synoviocytes Athanassios Fragoulis, Jendrik Laufs, Susanna Müller, Ulf Soppa, Stephanie Siegl, Lucy Reiss, Mersedeh Tohidnezhad, Christian Rosen, Klaus Tenbrock, Deike Varoga, Sebastian Lippross, Thomas Pufe, Christoph Wruck Arthritis Research & Therapy 2012, 14:R220 (27 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Changes in pain catastrophizing predict later changes in fibromyalgia clinical and experimental pain report: cross-lagged panel analyses of dispositional and situational catastrophizing Claudia M Campbell, Lea McCauley, Sara C Bounds, Vani A Mathur, Lora Conn, Mpepera Simango, Robert R Edwards, Kevin R Fontaine Arthritis Research & Therapy 2012, 14:R231 (25 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Double-blind, placebo-controlled randomized trial with adalimumab for treatment of juvenile onset ankylosing spondylitis (JoAS): significant short term improvement Gerd Horneff, Sigrid Fitter, Ivan Foeldvari, Kirsten Minden, Jasmin Kuemmerle-Deschner, Nicolay Tzaribacev, Angelika Thon, Michael Borte, Gerd Ganser, Rolf Trauzeddel, Hans-Iko Huppertz Arthritis Research & Therapy 2012, 14:R230 (24 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary A double-blind randomized trial found adalimumab treatment was significantly superior to placebo in the treatment of juvenile onset ankylosing spondylitis (AS), being well tolerated and highly effective.
		Research article The adipokine adiponectin has potent anti-fibrotic effects mediated via adenosine monophosphate-activated protein kinase: novel target for fibrosis therapy Feng Fang, Lei Liu, Yang Yang, Zenshiro Tamaki, Jun Wei, Roberta G Marangoni, Swati Bhattacharyya, Ross S Summer, Boping Ye, John Varga Arthritis Research & Therapy 2012, 14:R229 (23 October 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Activation of the adiponectin pathway has potent antifibrotic effects in normal and scleroderma fibroblasts, and is a potential therapeutic target to control fibrosis in scleroderma and other chronic fibrosing conditions.
		Research article Interleukin-29 modulates proinflammatory cytokine production in synovial inflammation of rheumatoid arthritis Fang Wang, Lingxiao Xu, Xiaoke Feng, Dunming Guo, Wenfeng Tan, Miaojia Zhang Arthritis Research & Therapy 2012, 14:R228 (19 October 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Th17 expansion in granulomatosis with polyangiitis (Wegener's): the role of disease activity, immune regulation and therapy Benjamin Wilde, Marielle Thewissen, Jan Damoiseaux, Marc Hilhorst, Pieter van Paassen, Oliver Witzke, Jan Cohen Tervaert Arthritis Research & Therapy 2012, 14:R227 (18 October 2012) Abstract \| Full text \| PDF \| PubMed