Arthritis Research & Therapy

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		Research article A novel in vitro bovine cartilage punch model for assessing the regeneration of focal cartilage defects with biocompatible bacterial nanocellulose David Pretzel, Stefanie Linss, Hannes Ahrem, Michaela Endres, Christian Kaps, Dieter Klemm, Raimund W. Kinne Arthritis Research & Therapy 2013, 15:R59 (14 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary In vitro bovine cartilage punch model is a novel tool developed to evaluate potential bio-materials for use in cartilage regeneration and repair.
		Research article Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism Edwin SL Chan, Hailing Liu, Patricia Fernandez, Alex Luna, Miguel Perez-Aso, Andreea M Bujor, Maria Trojanowska, Bruce N Cronstein Arthritis Research & Therapy 2013, 15:R58 (11 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.
		Correction Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthritis chondrocytes in vitro Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2013, 15:407 (10 May 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial A complicated liaison: IL-33 and IL-33R in arthritis pathogenesis Thomas Kamradt, Sebastian Drube Arthritis Research & Therapy 2013, 15:115 (2 May 2013) Abstract \| Full text \| PDF \| PubMed
		Commentary What can rheumatologists learn from translational cancer therapy? Jonathan P Sherlock, Andrew D Filer, John D Isaacs, Christopher D Buckley Arthritis Research & Therapy 2013, 15:114 (1 May 2013) Abstract \| Full text \| PDF \| PubMed
		Research article MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc Anshu Rastogi, Hyunchul Kim, Julianne D Twomey, Adam H Hsieh Arthritis Research & Therapy 2013, 15:R57 (27 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women Daniela Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling, Alicja Wolk Arthritis Research & Therapy 2013, 15:R56 (22 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Smoking only a few cigarettes a day more than doubles the risk of developing rheumatoid arthritis and although this risk will lower with time after smoking cessation, it can remain elevated 15 years later.
		Research article Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis Jerome Avouac, Maeva Vallucci, Vanessa Smith, Patricia Senet, Barbara Ruiz, Alberto Sulli, Carmen Pizzorni, Camille Frances, Gilles Chiocchia, Maurizio Cutolo, Yannick Allanore Arthritis Research & Therapy 2013, 15:R55 (19 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion Ami A Shah, Elena Schiopu, Laura K Hummers, Michael Wade, Kristine Phillips, Cynthia Anderson, Robert Wise, Francesco Boin, James R Seibold, Fredrick Wigley, Kristan D Rollins Arthritis Research & Therapy 2013, 15:R54 (18 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes Chih-Chang Yeh, Shun-Fu Chang, Ting-Ying Huang, Hsin-I Chang, Hsing-Chun Kuo, Yi-Chien Wu, Ching-Hsiang Hsieh, Chung-Sheng Shi, Cheng-Nan Chen Arthritis Research & Therapy 2013, 15:R53 (18 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFbeta1) gene in knee and hip osteoarthritis Stella G Muthuri, Sally Doherty, Weiya Zhang, Rose A Maciewicz, Kenneth Muir, Michael Doherty Arthritis Research & Therapy 2013, 15:R52 (18 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Anti-inflammatory properties of a dual PPARgamma/alpha agonist muraglitazar in in vitro and in vivo models Erja-Leena Paukkeri, Tiina Leppanen, Mira Lindholm, Mun Fei Yam, Mohd. Zaini Asmawi, Anne Kolmonen, Paula H Aulaskari, Eeva Moilanen Arthritis Research & Therapy 2013, 15:R51 (17 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Rpp25 is a major target of autoantibodies to the Th/To complex as measured by a novel chemiluminescent assay Michael Mahler, Cristina Gascon, Sima Patel, Angela Ceribelli, Marvin J Fritzler, Andreas Swart, Edward KL Chan, Minoru Satoh Arthritis Research & Therapy 2013, 15:R50 (12 April 2013) Abstract \| Full text \| PDF \| PubMed
		Review microRNA-mediated regulation of innate immune response in rheumatic diseases Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen, Yihong Yao Arthritis Research & Therapy 2013, 15:210 (9 April 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus Margareta Lantow, Ramya Sivakumar, Leilani Zeumer, Clive Wasserfall, Ying-Yi Zheng, Mark A Atkinson, Laurence Morel Arthritis Research & Therapy 2013, 15:R49 (8 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary B6.Sle2c2 mice are resistant to lupus due to a mutation in the granulocyte colony stimulating factor pathway, suggesting autoantibody production is inhibited by reduced neutrophil activation.
		Review Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms? Sarah L Tansley, Neil J McHugh, Lucy R Wedderburn Arthritis Research & Therapy 2013, 15:211 (8 April 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Marcelo H Petri, Minoru Satoh, Beatriz T Martin-Marquez, Raul Vargas-Ramírez, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Gonzalez, Lilia Andrade-Ortega, Olga Vera-Lastra, Mario Salazar-Páramo, Rosa E Prieto-Parra, Laura Gonzalez-Lopez, Jorge I Gamez-Nava, Hermes U Ramírez-Sánchez, Jason YF Chan, Steven J Ross, Edward KL Chan, Mónica Mercado Arthritis Research & Therapy 2013, 15:R48 (4 April 2013) Abstract \| Provisional PDF \| PubMed
		Letter Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' - authors' reply Qin Shi, Jamilah Abusarah, Ghayath Baroudi, Julio C Fernandes, Hassan Fahmi, Mohamed Benderdour Arthritis Research & Therapy 2013, 15:406 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' Di Wang, Shanshan Hu, Wei Wei Arthritis Research & Therapy 2013, 15:405 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
		Review Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases? Udo Oppermann Arthritis Research & Therapy 2013, 15:209 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Germline deletion of β2 microglobulin or CD1d reduces anti-phospholipid antibody, but increases autoantibodies against non-phospholipid antigens in the NZB/W F1 model of lupus Ram Singh, Jun-Qi Yang, Peter J Kim, Ramesh C Halder Arthritis Research & Therapy 2013, 15:R47 (27 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Exercise training in childhood-onset systemic lupus erythematosus: a controlled randomized trial Danilo ML Prado, Fabiana B Benatti, Ana L de Sá-Pinto, Ana P Hayashi, Bruno Gualano, Rosa MR Pereira, Adriana ME Sallum, Eloisa Bonfá, Clovis A Silva, Hamilton Roschel Arthritis Research & Therapy 2013, 15:R46 (26 March 2013) Abstract \| Provisional PDF \| PubMed
		Editorial Canonical Wnt signaling and caveolae play a role in intervertebral disc degeneration; the continuing saga of the mysterious notochordal cell Mark Erwin Arthritis Research & Therapy 2013, 15:113 (22 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Possible rheumatoid arthritis subtypes in terms of rheumatoid factor, depression, diagnostic delay and emotional expression: an exploratory case-control study Taavi Tillmann, Rajeev Krishnadas, Jonathan Cavanagh, KV Petrides Arthritis Research & Therapy 2013, 15:R45 (21 March 2013) Abstract \| Full text \| PDF \| PubMed
		Review Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy Daniel Aeberli, Georg Schett Arthritis Research & Therapy 2013, 15:208 (21 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Monitoring cartilage loss in the hands and wrists in rheumatoid arthritis with magnetic resonance imaging in a multi-center clinical trial: IMPRESS (NCT00425932) Charles G Peterfy, Ewa Olech, Julie C DiCarlo, Joan T Merrill, Peter J Countryman, Norman B Gaylis Arthritis Research & Therapy 2013, 15:R44 (20 March 2013) Abstract \| Provisional PDF \| PubMed
		Editorial Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation? Peter LEM van Lent, Wim B van den Berg Arthritis Research & Therapy 2013, 15:112 (20 March 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial Cardiovascular risk management in rheumatoid arthritis: are we still waiting for the first step? Mike JL Peters, Michael T Nurmohamed Arthritis Research & Therapy 2013, 15:111 (19 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Treatment of rheumatoid arthritis in the Medicare Current Beneficiary Survey Daniel H Solomon, Edward Yelin, Jeffrey N Katz, Bing Lu, Tamara Shaykevich, John Z Ayanian Arthritis Research & Therapy 2013, 15:R43 (18 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Medicare patients with rheumatoid arthritis are less likely to receive disease-modifying anti-rheumatic drug (DMARD) treatment if they are not seeing a rheumatologist, have a lower income, or are older.
		Research article Association between alcohol consumption and symptom severity and quality of life in patients with fibromyalgia Chul H Kim, Ann Vincent, Daniel J Clauw, Connie A Luedtke, Jeffrey M Thompson, Terry D Schneekloth, Terry H Oh Arthritis Research & Therapy 2013, 15:R42 (15 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Low to moderate alcohol consumption lessens symptom severity and betters quality of life for fibromyalgia patients when compared to no alcohol consumption.
		Review Perspectives on epigenetic-based immune intervention for rheumatic diseases Steven G Gray Arthritis Research & Therapy 2013, 15:207 (14 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity Pedro Recarte-Pelz, Dolors Tàssies, Gerard Espinosa, Begoña Hurtado, Núria Sala, Ricard Cervera, Joan Reverter, Pablo de Frutos Arthritis Research & Therapy 2013, 15:R41 (12 March 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Further evaluation of a claims-based algorithm to determine the effectiveness of biologics for rheumatoid arthritis using commercial claims data Jeffrey R Curtis, Benjamin Chastek, Laura Becker, David J Harrison, David Collier, Huifeng Yun, George J Joseph Arthritis Research & Therapy 2013, 15:404 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Response to 'Statins accelerate the onset of collagen type II-induced arthritis in mice'-authors' reply Rob J Vandebriel, Hilda JI De Jong, Eric R Gremmer, Olaf H Klungel, Jan-Willem Tervaert, Wout Slob, Jan W Van Der Laan, Henk Van Loveren Arthritis Research & Therapy 2013, 15:403 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Response to 'Statins accelerate the onset of collagen type II-induced arthritis in mice' Sylvain Mathieu, Sylvain Palat, Bruno Pereira, Jean-Louis Kemeny, Geoffroy Marceau, Claude Dubray, Martin Soubrier Arthritis Research & Therapy 2013, 15:402 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial Osteopontin - a biomarker for organ damage in paediatric lupus? Tracy A Briggs Arthritis Research & Therapy 2013, 15:110 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Functional neuronal network activity differs with cognitive dysfunction in childhood-onset systemic lupus erythematosus Mark W DiFrancesco, Darren R Gitelman, Marisa S Klein-Gitelman, Anna Carmela P Sagcal-Gironella, Frank Zelko, Dean Beebe, Todd Parrish, Jessica Hummel, Jun Ying, Hermine I Brunner Arthritis Research & Therapy 2013, 15:R40 (7 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Functional MRI (fMRI) detection of differential neuronal network activation could be a candidate imaging biomarker for neurocognitive dysfunction (NCD) in childhood-onset systemic lupus erythematosus.
		Correction Correction: Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease 13 - identification of a new biglycan cleavage site Jordi Monfort, Ginette Tardif, Pascal Reboul, François Mineau, Peter Roughley, Jean-Pierre Pelletier, Johanne Martel-Pelletier Arthritis Research & Therapy 2013, 15:401 (5 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease Der-Yuan Chen, Chi-Chen Lin, Yi-Ming Chen, Joung-Liang Lan, Wei-Ting Hung, Hsin-Hua Chen, Kuo-Lung Lai, Chia-Wei Hsieh Arthritis Research & Therapy 2013, 15:R39 (4 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The severity of experimental arthritis is independent of IL-36 receptor signaling Céline Lamacchia, Gaby Palmer, Emiliana Rodriguez, Praxedis Martin, Solenne Vigne, Christian A Seemayer, Dominique Talabot-Ayer, Jennifer E Towne, Cem Gabay Arthritis Research & Therapy 2013, 15:R38 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Evaluation of the novel folate receptor ligand [¹⁸F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis Yoony YJ Gent, Karin Weijers, Carla FM Molthoff, Albert D Windhorst, Marc C Huisman, Desirée EC Smith, Sumith A Kularatne, Gerrit Jansen, Philip S Low, Adriaan A Lammertsma, Conny J van der Laken Arthritis Research & Therapy 2013, 15:R37 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial Kidney disease in lupus is not always 'lupus nephritis' Hans-Joachim Anders, Jan J Weening Arthritis Research & Therapy 2013, 15:108 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
		Commentary Enhancing the reporting and transparency of rheumatology research: a guide to reporting guidelines Robin Christensen, Henning Bliddal, Marius Henriksen Arthritis Research & Therapy 2013, 15:109 (28 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Urinary CD8⁺T-cell counts discriminate between active and inactive lupus nephritis Sebastian Dolff, Wayel H Abdulahad, Suzanne Arends, Marcory CRF van Dijk, Pieter C Limburg, Cees GM Kallenberg, Marc Bijl Arthritis Research & Therapy 2013, 15:R36 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice Olivia Weigert, Caroline von Spee, Reinmar Undeutsch, Lutz Kloke, Jens Y Humrich, Gabriela Riemekasten Arthritis Research & Therapy 2013, 15:R35 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin? Jan L Bjersing, Malin Erlandsson, Maria I Bokarewa, Kaisa Mannerkorpi Arthritis Research & Therapy 2013, 15:R34 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age Roberta Caorsi, Loredana Lepore, Francesco Zulian, Maria Alessio, Achille Stabile, Antonella Insalaco, Martina Finetti, Antonella Battagliese, Giorgia Martini, Chiara Bibalo, Alberto Martini, Marco Gattorno Arthritis Research & Therapy 2013, 15:R33 (26 February 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial To target or not to target APRIL in systemic lupus erythematosus: that is the question! Jacques Morel, Michael Hahne Arthritis Research & Therapy 2013, 15:107 (25 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Periodic knee injections of collagen tripeptide delay cartilage degeneration in rabbit experimental osteoarthritis Takuya Naraoka, Yasuyuki Ishibashi, Eiichi Tsuda, Yuji Yamamoto, Tomomi Kusumi, Satoshi Toh Arthritis Research & Therapy 2013, 15:R32 (22 February 2013) Abstract \| Full text \| PDF \| PubMed
		Review CD154: the atherosclerotic risk factor in rheumatoid arthritis? Ghada S Hassan, Daniel Yacoub, Nada Alaaeddine, Amal Nadiri, Yahye Merhi, Walid Mourad Arthritis Research & Therapy 2013, 15:206 (22 February 2013) Abstract \| Full text \| PDF \| PubMed

	All
		Research article A novel in vitro bovine cartilage punch model for assessing the regeneration of focal cartilage defects with biocompatible bacterial nanocellulose David Pretzel, Stefanie Linss, Hannes Ahrem, Michaela Endres, Christian Kaps, Dieter Klemm, Raimund W. Kinne Arthritis Research & Therapy 2013, 15:R59 (14 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary In vitro bovine cartilage punch model is a novel tool developed to evaluate potential bio-materials for use in cartilage regeneration and repair.
		Research article Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism Edwin SL Chan, Hailing Liu, Patricia Fernandez, Alex Luna, Miguel Perez-Aso, Andreea M Bujor, Maria Trojanowska, Bruce N Cronstein Arthritis Research & Therapy 2013, 15:R58 (11 May 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.
		Correction Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthritis chondrocytes in vitro Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2013, 15:407 (10 May 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial A complicated liaison: IL-33 and IL-33R in arthritis pathogenesis Thomas Kamradt, Sebastian Drube Arthritis Research & Therapy 2013, 15:115 (2 May 2013) Abstract \| Full text \| PDF \| PubMed
		Commentary What can rheumatologists learn from translational cancer therapy? Jonathan P Sherlock, Andrew D Filer, John D Isaacs, Christopher D Buckley Arthritis Research & Therapy 2013, 15:114 (1 May 2013) Abstract \| Full text \| PDF \| PubMed
		Research article MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc Anshu Rastogi, Hyunchul Kim, Julianne D Twomey, Adam H Hsieh Arthritis Research & Therapy 2013, 15:R57 (27 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women Daniela Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling, Alicja Wolk Arthritis Research & Therapy 2013, 15:R56 (22 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary Smoking only a few cigarettes a day more than doubles the risk of developing rheumatoid arthritis and although this risk will lower with time after smoking cessation, it can remain elevated 15 years later.
		Research article Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis Jerome Avouac, Maeva Vallucci, Vanessa Smith, Patricia Senet, Barbara Ruiz, Alberto Sulli, Carmen Pizzorni, Camille Frances, Gilles Chiocchia, Maurizio Cutolo, Yannick Allanore Arthritis Research & Therapy 2013, 15:R55 (19 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion Ami A Shah, Elena Schiopu, Laura K Hummers, Michael Wade, Kristine Phillips, Cynthia Anderson, Robert Wise, Francesco Boin, James R Seibold, Fredrick Wigley, Kristan D Rollins Arthritis Research & Therapy 2013, 15:R54 (18 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes Chih-Chang Yeh, Shun-Fu Chang, Ting-Ying Huang, Hsin-I Chang, Hsing-Chun Kuo, Yi-Chien Wu, Ching-Hsiang Hsieh, Chung-Sheng Shi, Cheng-Nan Chen Arthritis Research & Therapy 2013, 15:R53 (18 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFbeta1) gene in knee and hip osteoarthritis Stella G Muthuri, Sally Doherty, Weiya Zhang, Rose A Maciewicz, Kenneth Muir, Michael Doherty Arthritis Research & Therapy 2013, 15:R52 (18 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Anti-inflammatory properties of a dual PPARgamma/alpha agonist muraglitazar in in vitro and in vivo models Erja-Leena Paukkeri, Tiina Leppanen, Mira Lindholm, Mun Fei Yam, Mohd. Zaini Asmawi, Anne Kolmonen, Paula H Aulaskari, Eeva Moilanen Arthritis Research & Therapy 2013, 15:R51 (17 April 2013) Abstract \| Provisional PDF \| PubMed
		Research article Rpp25 is a major target of autoantibodies to the Th/To complex as measured by a novel chemiluminescent assay Michael Mahler, Cristina Gascon, Sima Patel, Angela Ceribelli, Marvin J Fritzler, Andreas Swart, Edward KL Chan, Minoru Satoh Arthritis Research & Therapy 2013, 15:R50 (12 April 2013) Abstract \| Full text \| PDF \| PubMed
		Review microRNA-mediated regulation of innate immune response in rheumatic diseases Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen, Yihong Yao Arthritis Research & Therapy 2013, 15:210 (9 April 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus Margareta Lantow, Ramya Sivakumar, Leilani Zeumer, Clive Wasserfall, Ying-Yi Zheng, Mark A Atkinson, Laurence Morel Arthritis Research & Therapy 2013, 15:R49 (8 April 2013) Abstract \| Provisional PDF \| PubMed \| Editor’s summary B6.Sle2c2 mice are resistant to lupus due to a mutation in the granulocyte colony stimulating factor pathway, suggesting autoantibody production is inhibited by reduced neutrophil activation.
		Review Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms? Sarah L Tansley, Neil J McHugh, Lucy R Wedderburn Arthritis Research & Therapy 2013, 15:211 (8 April 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara Marcelo H Petri, Minoru Satoh, Beatriz T Martin-Marquez, Raul Vargas-Ramírez, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Gonzalez, Lilia Andrade-Ortega, Olga Vera-Lastra, Mario Salazar-Páramo, Rosa E Prieto-Parra, Laura Gonzalez-Lopez, Jorge I Gamez-Nava, Hermes U Ramírez-Sánchez, Jason YF Chan, Steven J Ross, Edward KL Chan, Mónica Mercado Arthritis Research & Therapy 2013, 15:R48 (4 April 2013) Abstract \| Provisional PDF \| PubMed
		Letter Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' - authors' reply Qin Shi, Jamilah Abusarah, Ghayath Baroudi, Julio C Fernandes, Hassan Fahmi, Mohamed Benderdour Arthritis Research & Therapy 2013, 15:406 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' Di Wang, Shanshan Hu, Wei Wei Arthritis Research & Therapy 2013, 15:405 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
		Review Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases? Udo Oppermann Arthritis Research & Therapy 2013, 15:209 (3 April 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Germline deletion of β2 microglobulin or CD1d reduces anti-phospholipid antibody, but increases autoantibodies against non-phospholipid antigens in the NZB/W F1 model of lupus Ram Singh, Jun-Qi Yang, Peter J Kim, Ramesh C Halder Arthritis Research & Therapy 2013, 15:R47 (27 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Exercise training in childhood-onset systemic lupus erythematosus: a controlled randomized trial Danilo ML Prado, Fabiana B Benatti, Ana L de Sá-Pinto, Ana P Hayashi, Bruno Gualano, Rosa MR Pereira, Adriana ME Sallum, Eloisa Bonfá, Clovis A Silva, Hamilton Roschel Arthritis Research & Therapy 2013, 15:R46 (26 March 2013) Abstract \| Provisional PDF \| PubMed
		Editorial Canonical Wnt signaling and caveolae play a role in intervertebral disc degeneration; the continuing saga of the mysterious notochordal cell Mark Erwin Arthritis Research & Therapy 2013, 15:113 (22 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Possible rheumatoid arthritis subtypes in terms of rheumatoid factor, depression, diagnostic delay and emotional expression: an exploratory case-control study Taavi Tillmann, Rajeev Krishnadas, Jonathan Cavanagh, KV Petrides Arthritis Research & Therapy 2013, 15:R45 (21 March 2013) Abstract \| Full text \| PDF \| PubMed
		Review Cortical remodeling during menopause, rheumatoid arthritis, glucocorticoid and bisphosphonate therapy Daniel Aeberli, Georg Schett Arthritis Research & Therapy 2013, 15:208 (21 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Monitoring cartilage loss in the hands and wrists in rheumatoid arthritis with magnetic resonance imaging in a multi-center clinical trial: IMPRESS (NCT00425932) Charles G Peterfy, Ewa Olech, Julie C DiCarlo, Joan T Merrill, Peter J Countryman, Norman B Gaylis Arthritis Research & Therapy 2013, 15:R44 (20 March 2013) Abstract \| Provisional PDF \| PubMed
		Editorial Mesenchymal stem cell therapy in osteoarthritis: advanced tissue repair or intervention with smouldering synovial activation? Peter LEM van Lent, Wim B van den Berg Arthritis Research & Therapy 2013, 15:112 (20 March 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial Cardiovascular risk management in rheumatoid arthritis: are we still waiting for the first step? Mike JL Peters, Michael T Nurmohamed Arthritis Research & Therapy 2013, 15:111 (19 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Treatment of rheumatoid arthritis in the Medicare Current Beneficiary Survey Daniel H Solomon, Edward Yelin, Jeffrey N Katz, Bing Lu, Tamara Shaykevich, John Z Ayanian Arthritis Research & Therapy 2013, 15:R43 (18 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Medicare patients with rheumatoid arthritis are less likely to receive disease-modifying anti-rheumatic drug (DMARD) treatment if they are not seeing a rheumatologist, have a lower income, or are older.
		Research article Association between alcohol consumption and symptom severity and quality of life in patients with fibromyalgia Chul H Kim, Ann Vincent, Daniel J Clauw, Connie A Luedtke, Jeffrey M Thompson, Terry D Schneekloth, Terry H Oh Arthritis Research & Therapy 2013, 15:R42 (15 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Low to moderate alcohol consumption lessens symptom severity and betters quality of life for fibromyalgia patients when compared to no alcohol consumption.
		Review Perspectives on epigenetic-based immune intervention for rheumatic diseases Steven G Gray Arthritis Research & Therapy 2013, 15:207 (14 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Vitamin K-dependent proteins GAS6 and Protein S and TAM receptors in patients of systemic lupus erythematosus: correlation with common genetic variants and disease activity Pedro Recarte-Pelz, Dolors Tàssies, Gerard Espinosa, Begoña Hurtado, Núria Sala, Ricard Cervera, Joan Reverter, Pablo de Frutos Arthritis Research & Therapy 2013, 15:R41 (12 March 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Further evaluation of a claims-based algorithm to determine the effectiveness of biologics for rheumatoid arthritis using commercial claims data Jeffrey R Curtis, Benjamin Chastek, Laura Becker, David J Harrison, David Collier, Huifeng Yun, George J Joseph Arthritis Research & Therapy 2013, 15:404 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Response to 'Statins accelerate the onset of collagen type II-induced arthritis in mice'-authors' reply Rob J Vandebriel, Hilda JI De Jong, Eric R Gremmer, Olaf H Klungel, Jan-Willem Tervaert, Wout Slob, Jan W Van Der Laan, Henk Van Loveren Arthritis Research & Therapy 2013, 15:403 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Letter Response to 'Statins accelerate the onset of collagen type II-induced arthritis in mice' Sylvain Mathieu, Sylvain Palat, Bruno Pereira, Jean-Louis Kemeny, Geoffroy Marceau, Claude Dubray, Martin Soubrier Arthritis Research & Therapy 2013, 15:402 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial Osteopontin - a biomarker for organ damage in paediatric lupus? Tracy A Briggs Arthritis Research & Therapy 2013, 15:110 (8 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Functional neuronal network activity differs with cognitive dysfunction in childhood-onset systemic lupus erythematosus Mark W DiFrancesco, Darren R Gitelman, Marisa S Klein-Gitelman, Anna Carmela P Sagcal-Gironella, Frank Zelko, Dean Beebe, Todd Parrish, Jessica Hummel, Jun Ying, Hermine I Brunner Arthritis Research & Therapy 2013, 15:R40 (7 March 2013) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Functional MRI (fMRI) detection of differential neuronal network activation could be a candidate imaging biomarker for neurocognitive dysfunction (NCD) in childhood-onset systemic lupus erythematosus.
		Correction Correction: Degradation of small leucine-rich repeat proteoglycans by matrix metalloprotease 13 - identification of a new biglycan cleavage site Jordi Monfort, Ginette Tardif, Pascal Reboul, François Mineau, Peter Roughley, Jean-Pierre Pelletier, Johanne Martel-Pelletier Arthritis Research & Therapy 2013, 15:401 (5 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Involvement of TLR7 MyD88-dependent signaling pathway in the pathogenesis of adult-onset Still's disease Der-Yuan Chen, Chi-Chen Lin, Yi-Ming Chen, Joung-Liang Lan, Wei-Ting Hung, Hsin-Hua Chen, Kuo-Lung Lai, Chia-Wei Hsieh Arthritis Research & Therapy 2013, 15:R39 (4 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The severity of experimental arthritis is independent of IL-36 receptor signaling Céline Lamacchia, Gaby Palmer, Emiliana Rodriguez, Praxedis Martin, Solenne Vigne, Christian A Seemayer, Dominique Talabot-Ayer, Jennifer E Towne, Cem Gabay Arthritis Research & Therapy 2013, 15:R38 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Evaluation of the novel folate receptor ligand [¹⁸F]fluoro-PEG-folate for macrophage targeting in a rat model of arthritis Yoony YJ Gent, Karin Weijers, Carla FM Molthoff, Albert D Windhorst, Marc C Huisman, Desirée EC Smith, Sumith A Kularatne, Gerrit Jansen, Philip S Low, Adriaan A Lammertsma, Conny J van der Laken Arthritis Research & Therapy 2013, 15:R37 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial Kidney disease in lupus is not always 'lupus nephritis' Hans-Joachim Anders, Jan J Weening Arthritis Research & Therapy 2013, 15:108 (1 March 2013) Abstract \| Full text \| PDF \| PubMed
		Commentary Enhancing the reporting and transparency of rheumatology research: a guide to reporting guidelines Robin Christensen, Henning Bliddal, Marius Henriksen Arthritis Research & Therapy 2013, 15:109 (28 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Urinary CD8⁺T-cell counts discriminate between active and inactive lupus nephritis Sebastian Dolff, Wayel H Abdulahad, Suzanne Arends, Marcory CRF van Dijk, Pieter C Limburg, Cees GM Kallenberg, Marc Bijl Arthritis Research & Therapy 2013, 15:R36 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article CD4+Foxp3+ regulatory T cells prolong drug-induced disease remission in (NZBxNZW) F1 lupus mice Olivia Weigert, Caroline von Spee, Reinmar Undeutsch, Lutz Kloke, Jens Y Humrich, Gabriela Riemekasten Arthritis Research & Therapy 2013, 15:R35 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Exercise and obesity in fibromyalgia: beneficial roles of IGF-1 and resistin? Jan L Bjersing, Malin Erlandsson, Maria I Bokarewa, Kaisa Mannerkorpi Arthritis Research & Therapy 2013, 15:R34 (27 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article The schedule of administration of canakinumab in cryopyrin associated periodic syndrome is driven by the phenotype severity rather than the age Roberta Caorsi, Loredana Lepore, Francesco Zulian, Maria Alessio, Achille Stabile, Antonella Insalaco, Martina Finetti, Antonella Battagliese, Giorgia Martini, Chiara Bibalo, Alberto Martini, Marco Gattorno Arthritis Research & Therapy 2013, 15:R33 (26 February 2013) Abstract \| Full text \| PDF \| PubMed
		Editorial To target or not to target APRIL in systemic lupus erythematosus: that is the question! Jacques Morel, Michael Hahne Arthritis Research & Therapy 2013, 15:107 (25 February 2013) Abstract \| Full text \| PDF \| PubMed
		Research article Periodic knee injections of collagen tripeptide delay cartilage degeneration in rabbit experimental osteoarthritis Takuya Naraoka, Yasuyuki Ishibashi, Eiichi Tsuda, Yuji Yamamoto, Tomomi Kusumi, Satoshi Toh Arthritis Research & Therapy 2013, 15:R32 (22 February 2013) Abstract \| Full text \| PDF \| PubMed
		Review CD154: the atherosclerotic risk factor in rheumatoid arthritis? Ghada S Hassan, Daniel Yacoub, Nada Alaaeddine, Amal Nadiri, Yahye Merhi, Walid Mourad Arthritis Research & Therapy 2013, 15:206 (22 February 2013) Abstract \| Full text \| PDF \| PubMed