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Letter   Free

Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro' - authors' reply

Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2013, 15:409 (24 May 2013)

Abstract | Provisional PDF

Letter   Free

Response to 'TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β-induced rat osteoarthritis chondrocytes in vitro'

Jing Ma, Ang Li, Shu Zhu, Xiao-Rui Cao, Guo-Xian Pei Arthritis Research & Therapy 2013, 15:408 (24 May 2013)

Abstract | Provisional PDF

Review   Subscription

Cardiovascular risk in pediatric-onset rheumatological diseases

Julie Barsalou, Timothy J Bradley, Earl D Silverman Arthritis Research & Therapy 2013, 15:212 (22 May 2013)

Abstract | Provisional PDF

Research article   Open Access

A novel in vitro bovine cartilage punch model for assessing the regeneration of focal cartilage defects with biocompatible bacterial nanocellulose

David Pretzel, Stefanie Linss, Hannes Ahrem, Michaela Endres, Christian Kaps, Dieter Klemm, Raimund W. Kinne Arthritis Research & Therapy 2013, 15:R59 (14 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

In vitro bovine cartilage punch model is a novel tool developed to evaluate potential bio-materials for use in cartilage regeneration and repair.

Research article   Open Access

Adenosine A2A receptors promote collagen production by a Fli1- and CTGF-mediated mechanism

Edwin SL Chan, Hailing Liu, Patricia Fernandez, Alex Luna, Miguel Perez-Aso, Andreea M Bujor, Maria Trojanowska, Bruce N Cronstein Arthritis Research & Therapy 2013, 15:R58 (11 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Adenosine promotion of dermal fibrosis in conditions such as scleroderma is mediated by the transcription factor Fli1 and growth factor CTFG, highlighting potential targets for future anti-fibrotic therapies.

Correction   Free

Correction: TNF/TNFR signal transduction pathway-mediated anti-apoptosis and anti-inflammatory effects of sodium ferulate on IL-1β- induced rat osteoarthritis chondrocytes in vitro

Jun Qin, Liang Shang, An-song Ping, Jing Li, Xiao-jun Li, Hong Yu, Jacques Magdalou, Liao-bin Chen, Hui Wang Arthritis Research & Therapy 2013, 15:407 (10 May 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Free

A complicated liaison: IL-33 and IL-33R in arthritis pathogenesis

Thomas Kamradt, Sebastian Drube Arthritis Research & Therapy 2013, 15:115 (2 May 2013)

Abstract | Full text | PDF | PubMed

Commentary   Subscription

What can rheumatologists learn from translational cancer therapy?

Jonathan P Sherlock, Andrew D Filer, John D Isaacs, Christopher D Buckley Arthritis Research & Therapy 2013, 15:114 (1 May 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

MMP-2 mediates local degradation and remodeling of collagen by annulus fibrosus cells of the intervertebral disc

Anshu Rastogi, Hyunchul Kim, Julianne D Twomey, Adam H Hsieh Arthritis Research & Therapy 2013, 15:R57 (27 April 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access Highly Accessed

Cigarette smoking and smoking cessation in relation to risk of rheumatoid arthritis in women

Daniela Di Giuseppe, Nicola Orsini, Lars Alfredsson, Johan Askling, Alicja Wolk Arthritis Research & Therapy 2013, 15:R56 (22 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Smoking only a few cigarettes a day more than doubles the risk of developing rheumatoid arthritis and although this risk will lower with time after smoking cessation, it can remain elevated 15 years later.

Research article   Open Access

Correlations between angiogenic factors and capillaroscopic patterns in systemic sclerosis

Jérôme Avouac, Maeva Vallucci, Vanessa Smith, Patricia Senet, Barbara Ruiz, Alberto Sulli, Carmen Pizzorni, Camille Frances, Gilles Chiocchia, Maurizio Cutolo, Yannick Allanore Arthritis Research & Therapy 2013, 15:R55 (19 April 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access Highly Accessed

Open label study of escalating doses of oral treprostinil diethanolamine in patients with systemic sclerosis and digital ischemia: pharmacokinetics and correlation with digital perfusion

Ami A Shah, Elena Schiopu, Laura K Hummers, Michael Wade, Kristine Phillips, Cynthia Anderson, Robert Wise, Francesco Boin, James R Seibold, Fredrick Wigley, Kristan D Rollins Arthritis Research & Therapy 2013, 15:R54 (18 April 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access

Shear stress modulates macrophage-induced urokinase plasminogen activator expression in human chondrocytes

Chih-Chang Yeh, Shun-Fu Chang, Ting-Ying Huang, Hsin-I Chang, Hsing-Chun Kuo, Yi-Chien Wu, Ching-Hsiang Hsieh, Chung-Sheng Shi, Cheng-Nan Chen Arthritis Research & Therapy 2013, 15:R53 (18 April 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access

Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFbeta1) gene in knee and hip osteoarthritis

Stella G Muthuri, Sally Doherty, Weiya Zhang, Rose A Maciewicz, Kenneth Muir, Michael Doherty Arthritis Research & Therapy 2013, 15:R52 (18 April 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access Highly Accessed

Anti-inflammatory properties of a dual PPARgamma/alpha agonist muraglitazar in in vitro and in vivo models

Erja-Leena Paukkeri, Tiina Leppänen, Mira Lindholm, Mun Yam, Mohd Asmawi, Anne Kolmonen, Paula H Aulaskari, Eeva Moilanen Arthritis Research & Therapy 2013, 15:R51 (17 April 2013)

Abstract | Provisional PDF | PubMed

Research article   Open Access Highly Accessed

Rpp25 is a major target of autoantibodies to the Th/To complex as measured by a novel chemiluminescent assay

Michael Mahler, Cristina Gascon, Sima Patel, Angela Ceribelli, Marvin J Fritzler, Andreas Swart, Edward KL Chan, Minoru Satoh Arthritis Research & Therapy 2013, 15:R50 (12 April 2013)

Abstract | Full text | PDF | PubMed

Review   Subscription Highly Accessed

microRNA-mediated regulation of innate immune response in rheumatic diseases

Xiaobing Luo, Koustubh Ranade, Ronel Talker, Bahija Jallal, Nan Shen, Yihong Yao Arthritis Research & Therapy 2013, 15:210 (9 April 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The granulocyte colony stimulating factor pathway regulates autoantibody production in a murine induced model of systemic lupus erythematosus

Margareta Lantow, Ramya Sivakumar, Leilani Zeumer, Clive Wasserfall, Ying-Yi Zheng, Mark A Atkinson, Laurence Morel Arthritis Research & Therapy 2013, 15:R49 (8 April 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

B6.Sle2c2 mice are resistant to lupus due to a mutation in the granulocyte colony stimulating factor pathway, suggesting autoantibody production is inhibited by reduced neutrophil activation.

Review   Subscription Highly Accessed

Adult and juvenile dermatomyositis: are the distinct clinical features explained by our current understanding of serological subgroups and pathogenic mechanisms?

Sarah L Tansley, Neil J McHugh, Lucy R Wedderburn Arthritis Research & Therapy 2013, 15:211 (8 April 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Implications in the difference of anti-Mi-2 and -p155/140 autoantibody prevalence in two dermatomyositis cohorts from Mexico City and Guadalajara

Marcelo H Petri, Minoru Satoh, Beatriz T Martin-Marquez, Raul Vargas-Ramírez, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Gonzalez, Lilia Andrade-Ortega, Olga Vera-Lastra, Mario Salazar-Páramo, Rosa E Prieto-Parra, Laura Gonzalez-Lopez, Jorge I Gamez-Nava, Hermes U Ramírez-Sánchez, Jason YF Chan, Steven J Ross, Edward KL Chan, Mónica Vázquez-Del Mercado Arthritis Research & Therapy 2013, 15:R48 (4 April 2013)

Abstract | Provisional PDF | PubMed

Letter   Free

Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis' - authors' reply

Qin Shi, Jamilah Abusarah, Ghayath Baroudi, Julio C Fernandes, Hassan Fahmi, Mohamed Benderdour Arthritis Research & Therapy 2013, 15:406 (3 April 2013)

Abstract | Full text | PDF | PubMed

Letter   Free

Response to 'Ramipril attenuates lipid peroxidation and cardiac fibrosis in an experimental model of rheumatoid arthritis'

Di Wang, Shanshan Hu, Wei Wei Arthritis Research & Therapy 2013, 15:405 (3 April 2013)

Abstract | Full text | PDF | PubMed

Review   Subscription

Why is epigenetics important in understanding the pathogenesis of inflammatory musculoskeletal diseases?

Udo Oppermann Arthritis Research & Therapy 2013, 15:209 (3 April 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Germline deletion of β2 microglobulin or CD1d reduces anti-phospholipid antibody, but increases autoantibodies against non-phospholipid antigens in the NZB/W F1 model of lupus

Ram Singh, Jun-Qi Yang, Peter J Kim, Ramesh C Halder Arthritis Research & Therapy 2013, 15:R47 (27 March 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Exercise training in childhood-onset systemic lupus erythematosus: a controlled randomized trial

Danilo ML Prado, Fabiana B Benatti, Ana L de Sá-Pinto, Ana P Hayashi, Bruno Gualano, Rosa MR Pereira, Adriana ME Sallum, Eloisa Bonfá, Clovis A Silva, Hamilton Roschel Arthritis Research & Therapy 2013, 15:R46 (26 March 2013)

Abstract | Provisional PDF | PubMed

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