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An in vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis
David D McErlain, Veronica Ulici, Mark R Darling, Joe S Gati, Vasek Pitelka, Frank Beier, David W Holdsworth Arthritis Research & Therapy 2012, 14:R26 (3 February 2012)
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Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies
Chih Long Liu, Stephanie Tangsombatvisit, Jacob M Rosenberg, Gil Mandelbaum, Emily C Gillespie, Or P Gozani, Ash A Alizadeh, Paul J Utz Arthritis Research & Therapy 2012, 14:R25 (2 February 2012)
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Therapy of lupus nephritis: lessons learned from clinical research and daily care of patients
Frédéric A Houssiau Arthritis Research & Therapy 2012, 14:202 (31 January 2012)
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A profile of immune response to herpesvirus is associated with radiographic damage in rheumatoid arthritis
John M Davis, Keith L Knutson, John A Skinner, Michael A Strausbauch, Cynthia S Crowson, Terry M Therneau, Peter J Wettstein, Eric L Matteson, Sherine E Gabriel Arthritis Research & Therapy 2012, 14:R24 (31 January 2012)
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Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
Yves Henrotin, Ali Mobasheri, Marc Marty Arthritis Research & Therapy 2012, 14:201 (30 January 2012)
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Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes
Raghunatha R Yammani, Richard F Loeser Arthritis Research & Therapy 2012, 14:R23 (30 January 2012)
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Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate, and azathioprine
Elena Schiopu, Kristine Phillips, Paul M MacDonald, Leslie J Crofford, Emily C Somers Arthritis Research & Therapy 2012, 14:R22 (27 January 2012)
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A randomised controlled trial of a self-management education program for osteoarthritis of the knee delivered by health professionals.
Sophie Coleman, N Kathryn Briffa, Graeme Carroll, Charles Inderjeeth, Nicola Cook, Jean McQuade Arthritis Research & Therapy 2012, 14:R21 (27 January 2012)
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Local administration of glucocorticoids decrease synovial citrullination in rheumatoid arthritis
Dimtrios Makrygiannakis, Shankar Revu, Marianne Engstrom, Erik af Klint, Anthony P Nicholas, Ger JM Pruijn, Anca I Catrina Arthritis Research & Therapy 2012, 14:R20 (27 January 2012)
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Editor’s summary
Glucocorticoid reduced levels of protein citrullination and the enzyme peptidylargininedeiminase 4 (PAD4) in the joints of patients with rheumatoid arthritis, and this was matched by a decrease in visible signs of inflammation.
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Restrictive pulmonary function is more prevalent in patients with ankylosing spondylitis than in matched population controls and is associated with impaired spinal mobility: a comparative study
Gunnhild Berdal, Silje Halvorsen, Desiree van der Heijde, Morten Mowe, Hanne Dagfinrud Arthritis Research & Therapy 2012, 14:R19 (25 January 2012)
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Editor’s summary
Reduced spinal mobility is associated with restrictive pulmonary function in patients with ankylosing spondylitis, emphasizing the importance of maintaining spinal flexibility in the management of the disease.
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Autoimmunity induced by human cytomegalovirus in patients with systemic lupus erythematosus
Cecilia Söderberg-Nauclér Arthritis Research & Therapy 2012, 14:101 (23 January 2012)
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Neutralization of IL-17 ameliorates uveitis but damages photoreceptors in a murine model of spondyloarthritis
Jelena M Kezic, Tibor T Glant, James T Rosenbaum, Holly L Rosenzweig Arthritis Research & Therapy 2012, 14:R18 (23 January 2012)
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Effect of in utero exposure to diethystilbesterol on lumbar and femoral bone, articular cartilage and the intervertebral disc in male and female adult mice progeny with and without swimming exercise
Sora Al Rowas, Rami Haddad, Rahul Gawri, Abdulaziz Al Ma'awi, Lorraine Chalifour, John Antoniou, Fackson Mwale Arthritis Research & Therapy 2012, 14:R17 (23 January 2012)
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Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice
Liesbet Lodewyckx, Frederic Cailotto, Sarah Thysen, Frank P Luyten, Rik J Lories Arthritis Research & Therapy 2012, 14:R16 (20 January 2012)
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Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-alpha treatment
Kaisa E Happonen, Tore Saxne, Pierre Geborek, Maria Andersson, Anders Bengtsson, Roger Hesselstrand, Dick Heinegard, Anna M Blom Arthritis Research & Therapy 2012, 14:R15 (20 January 2012)
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Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis
Seung-Jun Hwang, Bongkun Choi, Soon-Suk Kang, Jae-Ho Chang, Yong-Gil Kim, Yeon-Ho Chung, Dong Hyun Sohn, Min Wook So, Chang-Keun Lee, William H Robinson, Eun-Ju Chang Arthritis Research & Therapy 2012, 14:R14 (20 January 2012)
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A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee
Dawn Doré, Jonathon de Hoog, Graham Giles, Changhai Ding, Flavia Cicuttini, Graeme Jones Arthritis Research & Therapy 2012, 14:R13 (18 January 2012)
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The distribution pattern of critically short telomeres in human osteoarthritic knees
Maria Harbo, Laila Bendix, Anne-Christine Bay-Jensen, Jesper Graakjaer, Kent Søe, Thomas L Andersen, Per Kjaersgaard-Andersen, Steen Koelvraa, Jean-Marie Delaisse Arthritis Research & Therapy 2012, 14:R12 (18 January 2012)
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Editor’s summary
An increase in the number of cells with ultra short telomeres is associated with increased severity of osteoarthritis, proximity to the most damaged section of the joint, and with senescence.
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Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial
Dona L Fleishaker, Juan A Garcia Meijide, Andriy Petrov, Michael D Kohen, Xin Wang, Sujatha Menon, Thomas C Stock, Charles A Mebus, James M Goodrich, Howard B Mayer, Bernhardt G Zeiher Arthritis Research & Therapy 2012, 14:R11 (17 January 2012)
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Hyperuricemia and untreated gout are poor prognostic markers among those with a recent acute myocardial infarction
Eswar Krishnan, Bhavik J Pandya, Bharathi Lingala, Ali Hariri, Omar Dabbous Arthritis Research & Therapy 2012, 14:R10 (17 January 2012)
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A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation
Asako Chiba, Miho Mizuno, Chiharu Tomi, Ryohsuke Tajima, Iraide Alloza, Alessandra di Penta, Takashi Yamamura, Koen Vandenbroeck, Sachiko Miyake Arthritis Research & Therapy 2012, 14:R9 (17 January 2012)
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Identification and evaluation of novel synovial tissue biomarkers in rheumatoid arthritis by laser scanning cytometry
Christiane Fueldner, Anja Mittag, Jens Knauer, Maria Biskop, Pierre Hepp, Roger Scholz, Ulf Wagner, Ulrich Sack, Frank Emmrich, Attila Tárnok, Joerg Lehmann Arthritis Research & Therapy 2012, 14:R8 (17 January 2012)
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Usage of Skin care products and risk of Rheumatoid Arthritis: results from the Swedish EIRA study
Berit M Sverdrup, Henrik Källberg, Lars Klareskog, Lars Alfredsson, EIRA study group Arthritis Research & Therapy 2012, 14:R8 (13 January 2012)
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Editor’s summary
Normal usage of common cosmetics such as body lotions, skin creams and ointments, which often contain mineral oil, does not increase the risk for rheumatoid arthritis in the population in general.
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Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4
Dong Sohn, Jeremy Sokolove, Orr Sharpe, Jennifer C Erhart, Piyanka E Chandra, Lauren J Lahey, Tamsin M Lindstrom, Inyong Hwang, Katherine A Boyer, Thomas P Andriacchi, William H Robinson Arthritis Research & Therapy 2012, 14:R7 (8 January 2012)
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Safety, pharmacokinetics, and biologic activity of a novel monoclonal antibody targeting lymphotoxin-alpha: results of a phase I randomized, placebo-controlled trial
Brinda Emu, Diana Luca, Carolyn Offutt, Jane Grogan, Bernadette Rojkovich, Marna Williams, Meina Tang, Jim Xiao, June Lee, John Davis Arthritis Research & Therapy 2012, 14:R6 (8 January 2012)
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