Arthritis Research & Therapy

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		Research article TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome Seung-Ki Kwok, Mi-La Cho, Yang-Mi Her, Hye-Joa Oh, Mi-Kyung Park, Seon-Yeong Lee, Yun Woo, Ji Ju, Kyung-Su Park, Ho-Youn Kim, Sung-Hwan Park Arthritis Research & Therapy 2012, 14:R64 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Clinical features of symptomatic patellofemoral joint osteoarthritis George Peat, Rachel C Duncan, Laurence RJ Wood, Elaine Thomas, Sara Muller Arthritis Research & Therapy 2012, 14:R63 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts Alison M Connor, Nizar Mahomed, Rajiv Gandhi, Edward C Keystone, Stuart A Berger Arthritis Research & Therapy 2012, 14:R62 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Value of self-performed joint counts in rheumatoid arthritis patients near remission Helga Radner, Johannes Grisar, Josef S Smolen, Tanja Stamm, Daniel Aletaha Arthritis Res Ther 2012, 14:R61 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators? Joseph Paquet, Jean-Christophe Goebel, Camille Delaunay, Astrid Pinzano, Laurent Grossin, Christel Cournil-Henrionnet, Pierre Gillet, Patrick Netter, Jean-Yves Jouzeau, David Moulin Arthritis Research & Therapy 2012, 14:R60 (13 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis Kirsten Braem, Christophe M Deroose, Frank P Luyten, Rik J Lories Arthritis Research & Therapy 2012, 14:R59 (12 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Characterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate Cécile Lambert, Marianne Mathy-Hartert, Jean-Emile Dubuc, Eulàlia Montell, Josep Vergés, Carine Munaut, Agnès Noël, Yves Henrotin Arthritis Research & Therapy 2012, 14:R58 (12 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity YK Onno Teng, Gillian Wheater, Vanessa E Hogan, Philip Stocks, EW Nivine Levarht, Tom WJ Huizinga, Rene EM Toes, Jacob M van Laar Arthritis Research & Therapy 2012, 14:R57 (12 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Implication of new atherosclerotic carotid plaques in the cardiovascular outcome of patients with rheumatoid arthritis Miguel A González-Gay, Carlos González-Juanatey Arthritis Research & Therapy 2012, 14:105 (12 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The independent association between parathyroid hormone levels and hyperuricemia: a national population study Janet Y Hui, Jee Woong J Choi, David B Mount, Yanyan Zhu, Yuqing Zhang, Hyon K Choi Arthritis Research & Therapy 2012, 14:R56 (10 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article A systematic critical review on MRI in spondyloarthritis Bodil Arnbak, Charlotte Leboeuf-Yde, Tue Jensen Arthritis Research & Therapy 2012, 14:R55 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression Daniela Frölich, Daniela Blaβfeld, Karin Reiter, Claudia Giesecke, Capucine Daridon, Henrik E Mei, Gerd R Burmester, David M Goldenberg, Abdulagabar Salama, Thomas Dörner Arthritis Research & Therapy 2012, 14:R54 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Is IL-6 an appropriate target to treat spondyloarthritis patients refractory to anti-TNF therapy? a multicentre retrospective observational study Fernando Lekpa, Cécile Poulain, Daniel Wendling, Martin Soubrier, Michel De Bandt, Jean Berthelot, Philippe Gaudin, Eric Toussirot, Philippe Goupille, Thao Pham, Jérémie Sellam, Rémy Bruckert, Muriel Paul, Valérie Farrenq, Pascal Claudepierre, the Club Rhumatismes et Inflammation Arthritis Research & Therapy 2012, 14:R53 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Moving instead of asking? Performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis Salima FE van Weely, J Christiaan van Denderen, Martijn PM Steultjens, Marike van der Leeden, Michael T Nurmohamed, Joost Dekker, Ben AC Dijkmans, Irene E van der Horst-Bruinsma Arthritis Research & Therapy 2012, 14:R52 (8 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration Takashi Yurube, Toru Takada, Teppei Suzuki, Kenichiro Kakutani, Koichiro Maeno, Minoru Doita, Masahiro Kurosaka, Kotaro Nishida Arthritis Research & Therapy 2012, 14:R51 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis Marie Hudson, Janet Pope, Michael Mahler, Solène Tatibouet, Russell Steele, Murray Baron, Canadian Scleroderma Research Group (CSRG), Marvin J Fritzler Arthritis Research & Therapy 2012, 14:R50 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage Girish Ramaswamy, Philip Sohn, Alan Eberhardt, Rosa Serra Arthritis Research & Therapy 2012, 14:R49 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity Fumihito Suzuki, Tetsuo Kubota, Yasunari Miyazaki, Kinya Ishikawa, Masashi Ebisawa, Shunsei Hirohata, Takashi Ogura, Hidehiro Mizusawa, Toshio Imai, Nobuyuki Miyasaka, Toshihiro Nanki Arthritis Research & Therapy 2012, 14:R48 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Dutch translation and cross-cultural adaptation of the PROMIS^®physical function item bank and cognitive pre-test in Dutch arthritis patients Martijn AH Oude Voshaar, Peter M ten Klooster, Erik Taal, Eswar Krishnan, Mart AFJ van de Laar Arthritis Research & Therapy 2012, 14:R47 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The Patient-Reported Outcomes Measurement Information System (PROMIS) physical function item bank translated into Dutch is semantically and conceptually equivalent to the original, with all items comprehended by patients as intended.
		Research article Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study Johanna T Gustafsson, Julia F Simard, Iva Gunnarsson, Kerstin Elvin, Ingrid E Lundberg, Lars-Olof Hansson, Anders Larsson, Elisabet Svenungsson Arthritis Research & Therapy 2012, 14:R46 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes Chiyoko Sekine, Akemi Koyanagi, Noriko Koyama, Katsuto Hozumi, Shigeru Chiba, Hideo Yagita Arthritis Research & Therapy 2012, 14:R45 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study Evangelia Zampeli, Athanase Protogerou, Kimon Stamatelopoulos, Kalliopi Fragiadaki, Christina G Katsiari, Katerina Kyrkou, Christos M Papamichael, Myron Mavrikakis, Peter Nightingale, George D Kitas, Petros P Sfikakis Arthritis Research & Therapy 2012, 14:R44 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis Altan Ercan, Jing Cui, Melissa M Hazen, Franak Batliwalla, Louise Royle, Pauline M Rudd, Jonathan S Coblyn, Nancy Shadick, Michael E Weinblatt, Peter Gregersen, David M Lee, Peter A Nigrovic Arthritis Research & Therapy 2012, 14:R43 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Plasma proteins take their toll on the joint in osteoarthritis Steven R Goldring, Carla R Scanzello Arthritis Research & Therapy 2012, 14:111 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis Raquel López-Mejías, Carlos González-Juanatey, Mercedes García-Bermúdez, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Javier Llorca, Javier Martín, Miguel A González-Gay Arthritis Research & Therapy 2012, 14:R42 (1 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Taking responsibility for the early assessment and treatment of patients with musculoskeletal pain: a review and critical analysis Nadine E Foster, Jan Hartvigsen, Peter R Croft Arthritis Research & Therapy 2012, 14:205 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Clinical examination or whole-body magnetic resonance imaging: the Holy Grail of spondyloarthritis imaging Winston J Rennie Arthritis Research & Therapy 2012, 14:110 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Role of environmental factors in autoantibody production - importance of a detailed analysis in a small cohort Minoru Satoh, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:109 (29 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Inhibiting citrullination in rheumatoid arthritis: taking fuel from the fire Benjamin AC Fisher, Patrick J Venables Arthritis Research & Therapy 2012, 14:108 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study Berit M Sverdrup, Henrik Källberg, Lars Klareskog, Lars Alfredsson, Epidemiological Investigation of Rheumatoid Arthritis Study Group Arthritis Research & Therapy 2012, 14:R41 (28 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndrome Hongen Yin, Cuong Q Nguyen, Yuval Samuni, Toshimitsu Uede, Ammon B Peck, John A Chiorini Arthritis Research & Therapy 2012, 14:R40 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study Jon T Giles, Justyna Fert-Bober, Jin Park, Clifton O Bingham, Felipe Andrade, Karen Fox-Talbot, Dimitrios Pappas, Antony Rosen, Jennifer van Eyk, Joan M Bathon, Marc K Halushka Arthritis Research & Therapy 2012, 14:R39 (24 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial The BRIC-GARN Meeting 2011: of mice and men David S Pisetsky Arthritis Research & Therapy 2012, 14:107 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial How does BAFF activate B cells in patients with autoimmune diseases? Xavier Mariette Arthritis Research & Therapy 2012, 14:106 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-Terminal kinase pathway Sang-il Lee, David L Boyle, Andres Berdeja, Gary S Firestein Arthritis Research & Therapy 2012, 14:R38 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Abatacept versus other biologics in methotrexate inadequate responders with rheumatoid arthritis: you like tomato and I like tomahto... let's call the whole thing off Yusuf Yazici Arthritis Research & Therapy 2012, 14:104 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group Chingching Foocharoen, Alan Tyndall, Eric Hachulla, Edoardo Rosato, Yannick Allanore, Dominique Farge-Bancel, Paola Caramaschi, Paolo Airó, Starovojtova M Nikolaevna, José Pereira da Silva, Bojana Stamenkovic, Gabriela Riemekasten, Simona Rednic, Jean Sibilia, Piotr Wiland, Ingo Tarner, Vanessa Smith, Anna T Onken, Walid Abdel Atty Mohamed, Oliver Distler, Jadranka Morović-Vergles, Andrea Himsel, Paloma de la Peña Lefebvre, Thomas Hügle, Ulrich A Walker Arthritis Research & Therapy 2012, 14:R37 (20 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Severe erectile dysfunction is common amongst men with systemic sclerosis, appearing relatively early after disease diagnosis and associated with age; low treatment coverage suggests increased physician awareness is required.
		Research article Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis Agneta Zickert, Karin Palmblad, Birgitta Sundelin, Sangeeta Chavan, Kevin J Tracey, Annette Bruchfeld, Iva Gunnarsson Arthritis Research & Therapy 2012, 14:R36 (20 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Serum levels of high mobility group box 1 protein (HMGB1) are significantly increased in patients with lupus nephritis and remain raised after the initiation of immunosuppressive therapy, possibly indicating persistent inflammatory activity.
		Review Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus Erik A Korte, Patrick M Gaffney, David W Powell Arthritis Research & Therapy 2012, 14:204 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
		Review Endothelial progenitor cells: a new player in lupus? Sahena Haque, M Yvonne Alexander, Ian N Bruce Arthritis Research & Therapy 2012, 14:203 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Autonomic dysfunction in women with fibromyalgia J Derek Kingsley Arthritis Research & Therapy 2012, 14:103 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Anti-citrullinated fibronectin antibodies in rheumatoid arthritis are associated with human leukocyte antigen-DRB1 shared epitope alleles Joyce JBC van Beers, Annemiek Willemze, Judith Stammen-Vogelzangs, Jan W Drijfhout, René EM Toes, Ger J M Pruijn Arthritis Research & Therapy 2012, 14:R35 (17 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Serum levels of CXCL13 are associated with ultrasonographic synovitis and predict power Doppler persistence in early rheumatoid arthritis treated with non-biological disease-modifying anti-rheumatic drugs Serena Bugatti, Antonio Manzo, Francesca Benaglio, Catherine Klersy, Barbara Vitolo, Monica Todoerti, Garifallia Sakellariou, Carlomaurizio Montecucco, Roberto Caporali Arthritis Research & Therapy 2012, 14:R34 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis Natalie A Carter, Elizabeth C Rosser, Claudia Mauri Arthritis Research & Therapy 2012, 14:R32 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial Ellen M Ginzler, Stephen Wax, Anand Rajeswaran, Samuel Copt, Jan Hillson, Eleanor Ramos, Nora G Singer Arthritis Research & Therapy 2012, 14:R33 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
		Research article Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis Mitsuhiko Sato, Kenzo Uchida, Hideaki Nakajima, Tsuyoshi Miyazaki, Alexander Guerrero, Shuji Watanabe, Sally Roberts, Hisatoshi Baba Arthritis Research & Therapy 2012, 14:R31 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| F1000
		Research article Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up Mark Houseman, Catherine Potter, Nicola Marshall, Rachel Lakey, Tim Cawston, Ian Griffiths, Steven Young-Min, John D Isaacs Arthritis Research & Therapy 2012, 14:R30 (7 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The neuropeptide neuromedin U promotes autoantibody-mediated arthritis Sindhuja M Rao, Jennifer L Auger, Philippe Gaillard, Ralph Weissleder, Etsuko Wada, Richard Torres, Masayasu Kojima, Christophe Benoist, Diane Mathis, Bryce A Binstadt Arthritis Research & Therapy 2012, 14:R29 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Neuromedin U (NMU), a neuropeptide produced by bone-marrow-derived cells, promotes autoantibody-mediated arthritis in mice, suggesting NMU may be a potential therapeutic target in inflammatory arthritis.
		Research article Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis Scott W Graf, Sue Lester, Johannes C Nossent, Catherine L Hill, Susanna M Proudman, Anita Lee, Maureen Rischmueller Arthritis Research & Therapy 2012, 14:R28 (7 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Pre-disease pregnancy complications and systemic sclerosis: pathogenic or pre-clinical? Eliza Chakravarty Arthritis Research & Therapy 2012, 14:102 (6 February 2012) Abstract \| Full text \| PDF \| PubMed

	All
		Research article TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome Seung-Ki Kwok, Mi-La Cho, Yang-Mi Her, Hye-Joa Oh, Mi-Kyung Park, Seon-Yeong Lee, Yun Woo, Ji Ju, Kyung-Su Park, Ho-Youn Kim, Sung-Hwan Park Arthritis Research & Therapy 2012, 14:R64 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Clinical features of symptomatic patellofemoral joint osteoarthritis George Peat, Rachel C Duncan, Laurence RJ Wood, Elaine Thomas, Sara Muller Arthritis Research & Therapy 2012, 14:R63 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts Alison M Connor, Nizar Mahomed, Rajiv Gandhi, Edward C Keystone, Stuart A Berger Arthritis Research & Therapy 2012, 14:R62 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Value of self-performed joint counts in rheumatoid arthritis patients near remission Helga Radner, Johannes Grisar, Josef S Smolen, Tanja Stamm, Daniel Aletaha Arthritis Res Ther 2012, 14:R61 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators? Joseph Paquet, Jean-Christophe Goebel, Camille Delaunay, Astrid Pinzano, Laurent Grossin, Christel Cournil-Henrionnet, Pierre Gillet, Patrick Netter, Jean-Yves Jouzeau, David Moulin Arthritis Research & Therapy 2012, 14:R60 (13 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis Kirsten Braem, Christophe M Deroose, Frank P Luyten, Rik J Lories Arthritis Research & Therapy 2012, 14:R59 (12 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Characterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate Cécile Lambert, Marianne Mathy-Hartert, Jean-Emile Dubuc, Eulàlia Montell, Josep Vergés, Carine Munaut, Agnès Noël, Yves Henrotin Arthritis Research & Therapy 2012, 14:R58 (12 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity YK Onno Teng, Gillian Wheater, Vanessa E Hogan, Philip Stocks, EW Nivine Levarht, Tom WJ Huizinga, Rene EM Toes, Jacob M van Laar Arthritis Research & Therapy 2012, 14:R57 (12 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Implication of new atherosclerotic carotid plaques in the cardiovascular outcome of patients with rheumatoid arthritis Miguel A González-Gay, Carlos González-Juanatey Arthritis Research & Therapy 2012, 14:105 (12 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The independent association between parathyroid hormone levels and hyperuricemia: a national population study Janet Y Hui, Jee Woong J Choi, David B Mount, Yanyan Zhu, Yuqing Zhang, Hyon K Choi Arthritis Research & Therapy 2012, 14:R56 (10 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article A systematic critical review on MRI in spondyloarthritis Bodil Arnbak, Charlotte Leboeuf-Yde, Tue Jensen Arthritis Research & Therapy 2012, 14:R55 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression Daniela Frölich, Daniela Blaβfeld, Karin Reiter, Claudia Giesecke, Capucine Daridon, Henrik E Mei, Gerd R Burmester, David M Goldenberg, Abdulagabar Salama, Thomas Dörner Arthritis Research & Therapy 2012, 14:R54 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Is IL-6 an appropriate target to treat spondyloarthritis patients refractory to anti-TNF therapy? a multicentre retrospective observational study Fernando Lekpa, Cécile Poulain, Daniel Wendling, Martin Soubrier, Michel De Bandt, Jean Berthelot, Philippe Gaudin, Eric Toussirot, Philippe Goupille, Thao Pham, Jérémie Sellam, Rémy Bruckert, Muriel Paul, Valérie Farrenq, Pascal Claudepierre, the Club Rhumatismes et Inflammation Arthritis Research & Therapy 2012, 14:R53 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Moving instead of asking? Performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis Salima FE van Weely, J Christiaan van Denderen, Martijn PM Steultjens, Marike van der Leeden, Michael T Nurmohamed, Joost Dekker, Ben AC Dijkmans, Irene E van der Horst-Bruinsma Arthritis Research & Therapy 2012, 14:R52 (8 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration Takashi Yurube, Toru Takada, Teppei Suzuki, Kenichiro Kakutani, Koichiro Maeno, Minoru Doita, Masahiro Kurosaka, Kotaro Nishida Arthritis Research & Therapy 2012, 14:R51 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis Marie Hudson, Janet Pope, Michael Mahler, Solène Tatibouet, Russell Steele, Murray Baron, Canadian Scleroderma Research Group (CSRG), Marvin J Fritzler Arthritis Research & Therapy 2012, 14:R50 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage Girish Ramaswamy, Philip Sohn, Alan Eberhardt, Rosa Serra Arthritis Research & Therapy 2012, 14:R49 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity Fumihito Suzuki, Tetsuo Kubota, Yasunari Miyazaki, Kinya Ishikawa, Masashi Ebisawa, Shunsei Hirohata, Takashi Ogura, Hidehiro Mizusawa, Toshio Imai, Nobuyuki Miyasaka, Toshihiro Nanki Arthritis Research & Therapy 2012, 14:R48 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Dutch translation and cross-cultural adaptation of the PROMIS^®physical function item bank and cognitive pre-test in Dutch arthritis patients Martijn AH Oude Voshaar, Peter M ten Klooster, Erik Taal, Eswar Krishnan, Mart AFJ van de Laar Arthritis Research & Therapy 2012, 14:R47 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The Patient-Reported Outcomes Measurement Information System (PROMIS) physical function item bank translated into Dutch is semantically and conceptually equivalent to the original, with all items comprehended by patients as intended.
		Research article Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study Johanna T Gustafsson, Julia F Simard, Iva Gunnarsson, Kerstin Elvin, Ingrid E Lundberg, Lars-Olof Hansson, Anders Larsson, Elisabet Svenungsson Arthritis Research & Therapy 2012, 14:R46 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes Chiyoko Sekine, Akemi Koyanagi, Noriko Koyama, Katsuto Hozumi, Shigeru Chiba, Hideo Yagita Arthritis Research & Therapy 2012, 14:R45 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study Evangelia Zampeli, Athanase Protogerou, Kimon Stamatelopoulos, Kalliopi Fragiadaki, Christina G Katsiari, Katerina Kyrkou, Christos M Papamichael, Myron Mavrikakis, Peter Nightingale, George D Kitas, Petros P Sfikakis Arthritis Research & Therapy 2012, 14:R44 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis Altan Ercan, Jing Cui, Melissa M Hazen, Franak Batliwalla, Louise Royle, Pauline M Rudd, Jonathan S Coblyn, Nancy Shadick, Michael E Weinblatt, Peter Gregersen, David M Lee, Peter A Nigrovic Arthritis Research & Therapy 2012, 14:R43 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Plasma proteins take their toll on the joint in osteoarthritis Steven R Goldring, Carla R Scanzello Arthritis Research & Therapy 2012, 14:111 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis Raquel López-Mejías, Carlos González-Juanatey, Mercedes García-Bermúdez, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Javier Llorca, Javier Martín, Miguel A González-Gay Arthritis Research & Therapy 2012, 14:R42 (1 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Taking responsibility for the early assessment and treatment of patients with musculoskeletal pain: a review and critical analysis Nadine E Foster, Jan Hartvigsen, Peter R Croft Arthritis Research & Therapy 2012, 14:205 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Clinical examination or whole-body magnetic resonance imaging: the Holy Grail of spondyloarthritis imaging Winston J Rennie Arthritis Research & Therapy 2012, 14:110 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Role of environmental factors in autoantibody production - importance of a detailed analysis in a small cohort Minoru Satoh, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:109 (29 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Inhibiting citrullination in rheumatoid arthritis: taking fuel from the fire Benjamin AC Fisher, Patrick J Venables Arthritis Research & Therapy 2012, 14:108 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study Berit M Sverdrup, Henrik Källberg, Lars Klareskog, Lars Alfredsson, Epidemiological Investigation of Rheumatoid Arthritis Study Group Arthritis Research & Therapy 2012, 14:R41 (28 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndrome Hongen Yin, Cuong Q Nguyen, Yuval Samuni, Toshimitsu Uede, Ammon B Peck, John A Chiorini Arthritis Research & Therapy 2012, 14:R40 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study Jon T Giles, Justyna Fert-Bober, Jin Park, Clifton O Bingham, Felipe Andrade, Karen Fox-Talbot, Dimitrios Pappas, Antony Rosen, Jennifer van Eyk, Joan M Bathon, Marc K Halushka Arthritis Research & Therapy 2012, 14:R39 (24 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial The BRIC-GARN Meeting 2011: of mice and men David S Pisetsky Arthritis Research & Therapy 2012, 14:107 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial How does BAFF activate B cells in patients with autoimmune diseases? Xavier Mariette Arthritis Research & Therapy 2012, 14:106 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-Terminal kinase pathway Sang-il Lee, David L Boyle, Andres Berdeja, Gary S Firestein Arthritis Research & Therapy 2012, 14:R38 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Abatacept versus other biologics in methotrexate inadequate responders with rheumatoid arthritis: you like tomato and I like tomahto... let's call the whole thing off Yusuf Yazici Arthritis Research & Therapy 2012, 14:104 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Erectile dysfunction is frequent in systemic sclerosis and associated with severe disease: a study of the EULAR Scleroderma Trial and Research group Chingching Foocharoen, Alan Tyndall, Eric Hachulla, Edoardo Rosato, Yannick Allanore, Dominique Farge-Bancel, Paola Caramaschi, Paolo Airó, Starovojtova M Nikolaevna, José Pereira da Silva, Bojana Stamenkovic, Gabriela Riemekasten, Simona Rednic, Jean Sibilia, Piotr Wiland, Ingo Tarner, Vanessa Smith, Anna T Onken, Walid Abdel Atty Mohamed, Oliver Distler, Jadranka Morović-Vergles, Andrea Himsel, Paloma de la Peña Lefebvre, Thomas Hügle, Ulrich A Walker Arthritis Research & Therapy 2012, 14:R37 (20 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Severe erectile dysfunction is common amongst men with systemic sclerosis, appearing relatively early after disease diagnosis and associated with age; low treatment coverage suggests increased physician awareness is required.
		Research article Renal expression and serum levels of high mobility group box 1 protein in lupus nephritis Agneta Zickert, Karin Palmblad, Birgitta Sundelin, Sangeeta Chavan, Kevin J Tracey, Annette Bruchfeld, Iva Gunnarsson Arthritis Research & Therapy 2012, 14:R36 (20 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Serum levels of high mobility group box 1 protein (HMGB1) are significantly increased in patients with lupus nephritis and remain raised after the initiation of immunosuppressive therapy, possibly indicating persistent inflammatory activity.
		Review Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus Erik A Korte, Patrick M Gaffney, David W Powell Arthritis Research & Therapy 2012, 14:204 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
		Review Endothelial progenitor cells: a new player in lupus? Sahena Haque, M Yvonne Alexander, Ian N Bruce Arthritis Research & Therapy 2012, 14:203 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Autonomic dysfunction in women with fibromyalgia J Derek Kingsley Arthritis Research & Therapy 2012, 14:103 (20 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Anti-citrullinated fibronectin antibodies in rheumatoid arthritis are associated with human leukocyte antigen-DRB1 shared epitope alleles Joyce JBC van Beers, Annemiek Willemze, Judith Stammen-Vogelzangs, Jan W Drijfhout, René EM Toes, Ger J M Pruijn Arthritis Research & Therapy 2012, 14:R35 (17 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Serum levels of CXCL13 are associated with ultrasonographic synovitis and predict power Doppler persistence in early rheumatoid arthritis treated with non-biological disease-modifying anti-rheumatic drugs Serena Bugatti, Antonio Manzo, Francesca Benaglio, Catherine Klersy, Barbara Vitolo, Monica Todoerti, Garifallia Sakellariou, Carlomaurizio Montecucco, Roberto Caporali Arthritis Research & Therapy 2012, 14:R34 (15 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Interleukin-10 produced by B cells is crucial for the suppression of Th17/Th1 responses, induction of T regulatory type 1 cells and reduction of collagen-induced arthritis Natalie A Carter, Elizabeth C Rosser, Claudia Mauri Arthritis Research & Therapy 2012, 14:R32 (8 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Atacicept in combination with MMF and corticosteroids in lupus nephritis: results of a prematurely terminated trial Ellen M Ginzler, Stephen Wax, Anand Rajeswaran, Samuel Copt, Jan Hillson, Eleanor Ramos, Nora G Singer Arthritis Research & Therapy 2012, 14:R33 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
		Research article Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis Mitsuhiko Sato, Kenzo Uchida, Hideaki Nakajima, Tsuyoshi Miyazaki, Alexander Guerrero, Shuji Watanabe, Sally Roberts, Hisatoshi Baba Arthritis Research & Therapy 2012, 14:R31 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| F1000
		Research article Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up Mark Houseman, Catherine Potter, Nicola Marshall, Rachel Lakey, Tim Cawston, Ian Griffiths, Steven Young-Min, John D Isaacs Arthritis Research & Therapy 2012, 14:R30 (7 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The neuropeptide neuromedin U promotes autoantibody-mediated arthritis Sindhuja M Rao, Jennifer L Auger, Philippe Gaillard, Ralph Weissleder, Etsuko Wada, Richard Torres, Masayasu Kojima, Christophe Benoist, Diane Mathis, Bryce A Binstadt Arthritis Research & Therapy 2012, 14:R29 (7 February 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Neuromedin U (NMU), a neuropeptide produced by bone-marrow-derived cells, promotes autoantibody-mediated arthritis in mice, suggesting NMU may be a potential therapeutic target in inflammatory arthritis.
		Research article Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis Scott W Graf, Sue Lester, Johannes C Nossent, Catherine L Hill, Susanna M Proudman, Anita Lee, Maureen Rischmueller Arthritis Research & Therapy 2012, 14:R28 (7 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Pre-disease pregnancy complications and systemic sclerosis: pathogenic or pre-clinical? Eliza Chakravarty Arthritis Research & Therapy 2012, 14:102 (6 February 2012) Abstract \| Full text \| PDF \| PubMed