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Research article   Open Access

Correlation of C-reactive protein haplotypes with serum C-reactive protein level and response to anti-tumor necrosis factor therapy in UK rheumatoid arthritis patients: results from the Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate cohort

Darren Plant, Ibrahim Ibrahim, Mark Lunt, Stephen Eyre, Edward Flynn, Kimme L Hyrich, Ann W Morgan, Anthony G Wilson, John D Isaacs, BRAGGGSS, Anne Barton Arthritis Research & Therapy 2012, 14:R214 (7 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Predictors of mortality in connective tissue disease-associated pulmonary arterial hypertension: a cohort study

Gene-Siew Ngian, Wendy Stevens, David Prior, Eli Gabbay, Janet Roddy, Ai Tran, Robert Minson, Catherine Hill, Ken Chow, Joanne Sahhar, Susanna Proudman, Mandana Nikpour Arthritis Research & Therapy 2012, 14:R213 (5 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Biomechanical factors and physical examination findings in osteoarthritis of the knee: associations with tissue abnormalities assessed by conventional radiography and high-resolution 3.0 Tesla magnetic resonance imaging

Jesper Knoop, Joost Dekker, Jan-Paul Klein, Marike van der Leeden, Martin van der Esch, Dick Reiding, Ramon E Voorneman, Martijn Gerritsen, Leo D Roorda, Martijn PM Steultjens, Willem F Lems Arthritis Research & Therapy 2012, 14:R212 (5 October 2012)

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Research article   Open Access

Hepatic steatosis, carotid plaques and achieving MDA in psoriatic arthritis patients starting TNF-α blockers treatment: a prospective study

Matteo Nicola Dario Di Minno, Rosario Peluso, Salvatore Iervolino, Roberta Lupoli, Anna Russolillo, Giovanni Tarantino, Raffaele Scarpa Arthritis Research & Therapy 2012, 14:R211 (4 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

TLR4-mediated IL-12 production enhances IFN-γ and IL-1β production, which inhibits TGF-β production and promotes antibody-induced joint inflammation

Hye Kim, Doo Chung Arthritis Research & Therapy 2012, 14:R210 (4 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Impaired skeletal muscle microcirculation in systemic sclerosis

Sasan Partovi, Anja-Carina Schulte, Markus Aschwanden, Daniel Staub, Daniela Benz, Stephan Imfeld, Björn Jacobi, Pavel Broz, Kurt A Jäger, Martin Takes, Rolf W Huegli, Deniz Bilecen, Ulrich A Walker Arthritis Research & Therapy 2012, 14:R209 (4 October 2012)

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Research article   Open Access Highly Accessed

Dendritic cells provide a potential link between smoking and inflammation in rheumatoid arthritis

Marina G Kazantseva, John Highton, Lisa K Stamp, Paul A Hessian Arthritis Research & Therapy 2012, 14:R208 (4 October 2012)

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Research article   Open Access

Functional relationship between high mobility group A1 (HMGA1) protein and insulin-like growth factor-binding protein 3 (IGFBP-3) in human chondrocytes

Giorgio Gasparini, Marco De Gori, Francesco Paonessa, Eusebio Chiefari, Antonio Brunetti, Olimpio Galasso Arthritis Research & Therapy 2012, 14:R207 (4 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Targeting tumour necrosis factor alleviates signs and symptoms of inflammatory osteoarthritis of the knee

Walter P Maksymowych, Anthony S Russell, Peter Chiu, Alex Yan, Niall Jones, Tracey Clare, Robert GW Lambert Arthritis Research & Therapy 2012, 14:R206 (4 October 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology

Research article   Open Access

Chondrocalcinosis is common in the absence of knee involvement

Abhishek Abhishek, Sally Doherty, Rose Maciewicz, Kenneth Muir, Weiya Zhang, Michael Doherty Arthritis Research & Therapy 2012, 14:R205 (4 October 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Association of circulating levels of MMP-8 with mortality from respiratory disease in patients with rheumatoid arthritis

Derek L Mattey, Nicola B Nixon, Peter T Dawes Arthritis Research & Therapy 2012, 14:R204 (2 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Secretome analysis of chondroitin sulfate-treated chondrocytes reveals anti-angiogenic, anti-inflammatory and anti-catabolic properties

Valentina Calamia, Lucía Lourido, Patricia Fernández-Puente, Jesús Mateos, Beatriz Rocha, Eulalia Montell, Josep Vergés, Cristina Ruiz-Romero, Francisco J Blanco Arthritis Research & Therapy 2012, 14:R202 (2 October 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides

Monika Hansson, Linda Mathsson, Thomas Schlederer, Lena Israelsson, Per Matsson, Leonor Nogueira, Per-Johan Jakobsson, Karin Lundberg, Vivianne Malmström, Guy Serre, Rikard Holmdahl, Mats Nystrand, Lars Klareskog, Johan Rönnelid Arthritis Research & Therapy 2012, 14:R201 (1 October 2012)

Abstract | Full text | PDF | PubMed

Review   Free

Bone marrow edema and osteitis in rheumatoid arthritis: the imaging perspective

Fiona M McQueen Arthritis Research & Therapy 2012, 14:224 (28 September 2012)

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Editorial   Free Highly Accessed

4th International Forum on Rheumatoid Arthritis: Great Times Near the Great Wall

David S Pisetsky Arthritis Research & Therapy 2012, 14:125 (27 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Expression of IL-20 in synovium and lesional skin of patients with psoriatic arthritis: differential response to alefacept treatment

Maria C Lebre, Christina L Jonckheere, Maarten C Kraan, Arno WR van Kuijk, Jan D Bos, Menno de Rie, Danielle M Gerlag, Paul P Tak Arthritis Research & Therapy 2012, 14:R200 (24 September 2012)

Abstract | Full text | PDF | PubMed

Review   Free Highly Accessed

Common variable immunodeficiency - an update

Ulrich Salzer, Klaus Warnatz, Hans Peter Arthritis Research & Therapy 2012, 14:223 (24 September 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Free

Ways forward to identify new ACPA targets in RA

A Jimmy Ytterberg, Vivianne Malmström Arthritis Research & Therapy 2012, 14:124 (24 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development

Andrew D Cook, Jarrad Pobjoy, Stefan Steidl, Manuela Dürr, Emma L Braine, Amanda L Turner, Derek C Lacey, John A Hamilton Arthritis Research & Therapy 2012, 14:R199 (20 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Ultrasound of metacarpophalangeal joints is a sensitive and reliable endpoint for drug therapies in rheumatoid arthritis: results of a randomized, two-center placebo-controlled study

Matthew W Seymour, Stephen Kelly, Chan R Beals, Marie-Pierre Malice, James A Bolognese, Bernard J Dardzinski, Amy S Cheng, Corinne E Cummings, Steven S Smugar, Catherine McClinton, Amy Fox, William M Dooley, Constantino Pitzalis, Peter C Taylor Arthritis Research & Therapy 2012, 14:R198 (12 September 2012)

Abstract | Full text | PDF | PubMed

Letter   Free

Response to 'Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4' - authors' reply

Dong Sohn, Jeremy Sokolove, Orr Sharpe, Jennifer C Erhart, Piyanka E Chandra, Lauren J Lahey, Tamsin M Lindstrom, Inyong Hwang, Katherine A Boyer, Thomas P Andriacchi, William H Robinson Arthritis Research & Therapy 2012, 14:406 (12 September 2012)

Abstract | Full text | PDF | PubMed

Letter   Free

Response to 'Plasma proteins present in osteoarthritic synovial fluid can stimulate cytokine production via Toll-like receptor 4'

Francesca Oliviero, Anna Scanu, Jean-Michel Dayer, Ugo Fiocco, Paolo Sfriso, Leonardo Punzi Arthritis Research & Therapy 2012, 14:405 (12 September 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Matrilin-3 Induction of IL-1 receptor antagonist Is required for up-regulating collagen II and aggrecan and down-regulating ADAMTS-5 gene expression

Chathuraka T Jayasuriya, Mary B Goldring, Richard Terek, Qian Chen Arthritis Research & Therapy 2012, 14:R197 (11 September 2012)

Abstract | Full text | PDF | PubMed

Letter   Free

Response to 'Fragment of tegument protein pp65 of human cytomegalovirus induces autoantibodies in BALB/c mice'

Gn Kim, Think-You Kim Arthritis Research & Therapy 2012, 14:404 (10 September 2012)

Abstract | Full text | PDF | PubMed

Review   Free

Idiopathic CD4 lymphocytopenia: a case of missing, wandering or ineffective T cells

Dimitrios Zonios, Virginia Sheikh, Irini Sereti Arthritis Research & Therapy 2012, 14:222 (31 August 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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