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Research article   Open Access Highly Accessed

MMP13 is a critical target gene during the progression of osteoarthritis

Meina Wang, Erik R Sampson, Hongting Jin, Jia Li, Qiao H Ke, Hee-Jeong Im, Di Chen Arthritis Research & Therapy 2013, 15:R5 (8 January 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis - a systematic review of the literature

David F Ten Cate, Jolanda J Luime, Nanno Swen, Andreas H Gerards, Mike H De Jager, Natalja M Basoski, Johanna MW Hazes, Cees J Haagsma, Johannes WG Jacobs Arthritis Research & Therapy 2013, 15:R4 (8 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Ultrasonography has added value to clinical examination in diagnosing early rheumatoid arthritis and assessing remission, which could facilitate the provision of earlier and more effective treatments.

Research article   Open Access

OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population

Yongqing Jiang, Meng Yao, Qingpeng Liu, Changwei Zhou Arthritis Research & Therapy 2013, 15:R3 (5 January 2013)

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Research article   Open Access

Low-field magnetic resonance imaging study on carpal arthritis in systemic sclerosis - low-grade erosive arthritis of carpal bones is an unexpected and frequent disease manifestation

Elif Akbayrak, Robert Dinser, Ulf Müller-Ladner, Ingo H Tarner Arthritis Research & Therapy 2013, 15:R2 (4 January 2013)

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Research article   Open Access

Persistence of antibody response 1.5 years after vaccination using 7-valent pneumococcal conjugate vaccine in patients with arthritis treated with different antirheumatic drugs

Meliha Crnkic Kapetanovic, Tore Saxne, Lennart Truedsson, Pierre Geborek Arthritis Research & Therapy 2013, 15:R1 (4 January 2013)

Abstract | Full text | PDF | PubMed | F1000 Biology

Editorial   Free

Lupus nephritis - alarmins may sound the alarm?

Tianfu Wu, Chandra Mohan Arthritis Research & Therapy 2012, 14:129 (31 December 2012)

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Review   Subscription

T cells in myositis

Vivianne Malmström, Paulius Venalis, Inka Albrecht Arthritis Research & Therapy 2012, 14:230 (28 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor

Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper Broen, Madelon C Vonk, José Callejas, Patricia Carreira, Luis Rodríguez-Rodríguez, Rosa García-Portales, Miguel A González-Gay, Ivan Castellví, María Camps, Carlos Tolosa, Esther Vicente-Rabaneda, María Egurbide, the Spanish Scleroderma Group, Annemie J Schuerwegh, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Paul Shiels, Ariane Herrick, Jane Worthington, Christopher Denton, Timothy RDJ Radstake, Carmen Fonseca, Javier Martin Arthritis Research & Therapy 2012, 14:R273 (27 December 2012)

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Review   Subscription

Inflammatory lesions in the bone marrow of rheumatoid arthritis patients: a morphological perspective

Serena Bugatti, Antonio Manzo, Roberto Caporali, Carlomaurizio Montecucco Arthritis Research & Therapy 2012, 14:229 (27 December 2012)

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Editorial   Free Highly Accessed

Imaging joints for calcium pyrophosphate crystal deposition: a knock to the knees

Robert Terkeltaub Arthritis Research & Therapy 2012, 14:128 (27 December 2012)

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Research article   Open Access

Ghrelin and adipokines as circulating markers of disease activity in patients with Takayasu arteritis

Hatice Yilmaz, Vedat Gerdan, Didem Kozaci, Dilek Solmaz, Servet Akar, Gercek Can, Aytac Gulcu, Yigit Goktay, Ismail Sari, Merih Birlik, Nurullah Akkoc, Fatos Onen Arthritis Research & Therapy 2012, 14:R272 (21 December 2012)

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Editorial   Free

Can measuring urinary biomarkers improve the management of lupus nephritis?

Anisur Rahman Arthritis Research & Therapy 2012, 14:127 (19 December 2012)

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Editorial   Free

Rheumatology meets radiology in the hot soup of Gutta

Tim L Jansen Arthritis Research & Therapy 2012, 14:126 (19 December 2012)

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Research article   Open Access

Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis

Ilka Knütter, Rico Hiemann, Therese Brumma, Thomas Büttner, Kai Großmann, Marco Cusini, Francesca Pregnolato, Maria Borghi, Ursula Anderer, Karsten Conrad, Dirk Reinhold, Dirk Roggenbuck, Elena Csernok Arthritis Research & Therapy 2012, 14:R271 (14 December 2012)

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Research article   Open Access Highly Accessed

Suboptimal cardiovascular risk factor identification and management in patients with rheumatoid arthritis: a cohort analysis

Shailey S Desai, James D Myles, Mariana J Kaplan Arthritis Research & Therapy 2012, 14:R270 (13 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Autoantibody-mediated arthritis in the absence of C3 and activating Fcγ receptors: C5 is activated by the coagulation cascade

Jennifer L Auger, Stefanie Haasken, Bryce A Binstadt Arthritis Research & Therapy 2012, 14:R269 (13 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes

Linghui Dai, Xin Zhang, Xiaoqing Hu, Chunyan Zhou, Yingfang Ao Arthritis Research & Therapy 2012, 14:R268 (10 December 2012)

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Research article   Open Access

The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells

John Antoniou, Hong Wang, Abdulrahman M Alaseem, Lisbet Haglund, Peter J Roughley, Fackson Mwale Arthritis Research & Therapy 2012, 14:R267 (10 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis

Lieying Fan, Qiang Wang, Rongqing Liu, Ming Zong, Dongyi He, Hui Zhang, Yuanyuan Ding, Jianwei Ma Arthritis Research & Therapy 2012, 14:R266 (10 December 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology

Research article   Open Access Highly Accessed

Efficacy and safety of lenalidomide for refractory cutaneous lupus erythematosus

Josefina Cortés-Hernández, Gabriela Ávila, Miquel Vilardell-Tarrés, Josep Ordi-Ros Arthritis Research & Therapy 2012, 14:R265 (7 December 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

Lenalidomide, a thalidomide derivative, is effective and safe for the treatment of refractory cutaneous lupus erythematosus in patients recruited to a phase II clinical study.

Research article   Open Access

Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis

Erik JM Toonen, Pilar Barrera, Jaap Fransen, Arjan PM de Brouwer, Agnes M Eijsbouts, Pierre Miossec, Hubert Marotte, Hans Scheffer, Piet LCM van Riel, Barbara Franke, Marieke JH Coenen Arthritis Research & Therapy 2012, 14:R264 (7 December 2012)

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Research article   Open Access Highly Accessed

Disease activity and cognition in rheumatoid arthritis: an open label pilot study

Graham Raftery, Jiabao He, Ruth Pearce, Daniel Birchall, Julia L Newton, Andrew M Blamire, John D Isaacs Arthritis Research & Therapy 2012, 14:R263 (4 December 2012)

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Research article   Open Access Highly Accessed

Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model

Anika I Tsuchida, Michiel Beekhuizen, Marijn Rutgers, Gerjo JVM van Osch, Joris EJ Bekkers, Arjan GJ Bot, Bernd Geurts, Wouter JA Dhert, Daniel BF Saris, Laura B Creemers Arthritis Research & Therapy 2012, 14:R262 (3 December 2012)

Abstract | Full text | PDF | PubMed

Review   Free Highly Accessed

An update on the hyper-IgE syndromes

Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher Arthritis Research & Therapy 2012, 14:228 (30 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Free Highly Accessed

Biologic adjuvants for fracture healing

Mandeep S Virk, Jay R Lieberman Arthritis Research & Therapy 2012, 14:225 (30 November 2012)

Abstract | Full text | PDF | PubMed

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