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Research article   Open Access

Automated interpretation of ANCA patterns - a new approach in the serology of ANCA-associated vasculitis

Ilka Knütter, Rico Hiemann, Therese Brumma, Thomas Büttner, Kai Großmann, Marco Cusini, Francesca Pregnolato, Maria Borghi, Ursula Anderer, Karsten Conrad, Dirk Reinhold, Dirk Roggenbuck, Elena Csernok Arthritis Research & Therapy 2012, 14:R271 (14 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Suboptimal cardiovascular risk factor identification and management in patients with rheumatoid arthritis: a cohort analysis

Shailey S Desai, James D Myles, Mariana J Kaplan Arthritis Research & Therapy 2012, 14:R270 (13 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Autoantibody-mediated arthritis in the absence of C3 and activating Fcγ receptors: C5 is activated by the coagulation cascade

Jennifer L Auger, Stefanie Haasken, Bryce A Binstadt Arthritis Research & Therapy 2012, 14:R269 (13 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Silencing of microRNA-101 prevents IL-1β-induced extracellular matrix degradation in chondrocytes

Linghui Dai, Xin Zhang, Xiaoqing Hu, Chunyan Zhou, Yingfang Ao Arthritis Research & Therapy 2012, 14:R268 (10 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

The effect of Link N on differentiation of human bone marrow-derived mesenchymal stem cells

John Antoniou, Hong Wang, Abdulrahman M Alaseem, Lisbet Haglund, Peter J Roughley, Fackson Mwale Arthritis Research & Therapy 2012, 14:R267 (10 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Citrullinated fibronectin inhibits apoptosis and promotes the secretion of pro-inflammatory cytokines in fibroblast-like synoviocytes in rheumatoid arthritis

Lieying Fan, Qiang Wang, Rongqing Liu, Ming Zong, Dongyi He, Hui Zhang, Yuanyuan Ding, Jianwei Ma Arthritis Research & Therapy 2012, 14:R266 (10 December 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology

Research article   Open Access Highly Accessed

Efficacy and safety of lenalidomide for refractory cutaneous lupus erythematosus

Josefina Cortés-Hernández, Gabriela Ávila, Miquel Vilardell-Tarrés, Josep Ordi-Ros Arthritis Research & Therapy 2012, 14:R265 (7 December 2012)

Abstract | Full text | PDF | PubMed | F1000 Biology |  Editor’s summary

Lenalidomide, a thalidomide derivative, is effective and safe for the treatment of refractory cutaneous lupus erythematosus in patients recruited to a phase II clinical study.

Research article   Open Access

Meta-analysis identified the TNFA -308G > A promoter polymorphism as a risk factor for disease severity in patients with rheumatoid arthritis

Erik JM Toonen, Pilar Barrera, Jaap Fransen, Arjan PM de Brouwer, Agnes M Eijsbouts, Pierre Miossec, Hubert Marotte, Hans Scheffer, Piet LCM van Riel, Barbara Franke, Marieke JH Coenen Arthritis Research & Therapy 2012, 14:R264 (7 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Disease activity and cognition in rheumatoid arthritis: an open label pilot study

Graham Raftery, Jiabao He, Ruth Pearce, Daniel Birchall, Julia L Newton, Andrew M Blamire, John D Isaacs Arthritis Research & Therapy 2012, 14:R263 (4 December 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Interleukin-6 is elevated in synovial fluid of patients with focal cartilage defects and stimulates cartilage matrix production in an in vitro regeneration model

Anika I Tsuchida, Michiel Beekhuizen, Marijn Rutgers, Gerjo JVM van Osch, Joris EJ Bekkers, Arjan GJ Bot, Bernd Geurts, Wouter JA Dhert, Daniel BF Saris, Laura B Creemers Arthritis Research & Therapy 2012, 14:R262 (3 December 2012)

Abstract | Full text | PDF | PubMed

Review   Subscription Highly Accessed

An update on the hyper-IgE syndromes

Patrick FK Yong, Alexandra F Freeman, Karin R Engelhardt, Steven Holland, Jennifer M Puck, Bodo Grimbacher Arthritis Research & Therapy 2012, 14:228 (30 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Subscription Highly Accessed

Biologic adjuvants for fracture healing

Mandeep S Virk, Jay R Lieberman Arthritis Research & Therapy 2012, 14:225 (30 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Markers of intestinal inflammation in patients with ankylosing spondylitis: a pilot study

Franziska G Matzkies, Stephan R Targan, Dror Berel, Carol J Landers, John D Reveille, Dermot PB McGovern, Michael H Weisman Arthritis Research & Therapy 2012, 14:R261 (29 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Raised circulating tenascin-C in rheumatoid arthritis

Theresa H Page, Peter J Charles, Anna M Piccinini, Vicky Nicolaidou, Peter C Taylor, Kim S Midwood Arthritis Research & Therapy 2012, 14:R260 (29 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Interleukin-32-induced thymic stromal lymphopoietin plays a critical role in macrophage differentiation through the activation of caspase-1 in vitro

Hyun-Ja Jeong, Sun-Young Nam, Hyun-A Oh, Na-Ra Han, Young-Sick Kim, Phil-Dong Moon, Seung-Youp Shin, Min-Ho Kim, Hyung-Min Kim Arthritis Research & Therapy 2012, 14:R259 (28 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

The role of inflammation, the autonomic nervous system and classical cardiovascular disease risk factors on subendocardial viability ratio in patients with RA: a cross-sectional and longitudinal study

Aamer Sandoo, Athanassios D Protogerou, James Hodson, Jacqueline P Smith, Evi Zampeli, Petros P Sfikakis, George D Kitas Arthritis Research & Therapy 2012, 14:R258 (28 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Association of a BMP5 microsatellite with knee osteoarthritis: case-control study

Cristina Rodriguez-Fontenla, Andrew Carr, Juan J Gomez-Reino, Aspasia Tsezou, John Loughlin, Antonio Gonzalez Arthritis Research & Therapy 2012, 14:R257 (27 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Intensity-dependent effect of treadmill running on lubricin metabolism of rat articular cartilage

Guo-Xin Ni, Lei Lei, Yue-Zhu Zhou Arthritis Research & Therapy 2012, 14:R256 (24 November 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

High-intensity running in rats lowers lubricin content of joints and increases damage to cartilage while lower intensity running increases lubricin levels and improves joint fitness.

Research article   Open Access Highly Accessed

A regulatory effect of IL-21 on T follicular helper-like cell and B cell in rheumatoid arthritis

Rui Liu, Qian Wu, Dinglei Su, Nan Che, Haifeng Chen, Linyu Geng, Jinyun Chen, Wanjun Chen, Xia Li, Lingyun Sun Arthritis Research & Therapy 2012, 14:R255 (23 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Adherence to a treat-to-target strategy in early rheumatoid arthritis: results of the DREAM remission induction cohort

Marloes Vermeer, Hillechiena H Kuper, Hein J Bernelot Moens, Monique Hoekstra, Marcel D Posthumus, Piet LCM van Riel, Mart AFJ van de Laar Arthritis Research & Therapy 2012, 14:R254 (23 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Excessive bone formation in a mouse model of ankylosing spondylitis is associated with decreases in Wnt pathway inhibitors

Katelin R Haynes, Allison R Pettit, Ran Duan, Hsu-Wen Tseng, Tibor T Glant, Matthew A Brown, Gethin P Thomas Arthritis Research & Therapy 2012, 14:R253 (22 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

APRIL, a proliferation-inducing ligand, as a potential marker of lupus nephritis

Worapot Treamtrakanpon, Pornpen Tantivitayakul, Thitima Benjachat, Poorichaya Somparn, Wipawee Kittikowit, Somchai Eiam-ong, Asada Leelahavanichkul, Nattiya Hirankarn, Yingyos Avihingsanon Arthritis Research & Therapy 2012, 14:R252 (21 November 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Reverse regulation of soluble receptor for advanced glycation end products and proinflammatory factor resistin and S100A12 in Kawasaki disease

Yanqi Qi, Fangqi Gong, Qing Zhang, Chunhong Xie, Wei Wang, Songling Fu Arthritis Research & Therapy 2012, 14:R251 (21 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Polymorphisms in peptidylarginine deiminase associate with rheumatoid arthritis in diverse Asian populations: evidence from MyEIRA study and meta-analysis

Chun Too, Shahnaz Murad, Jasbir Dhaliwal, Per Larsson, Xia Jiang, Bo Ding, Lars Alfredsson, Lars Klareskog, Leonid Padyukov Arthritis Research & Therapy 2012, 14:R250 (19 November 2012)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Matrix to predict rapid radiographic progression of early rheumatoid arthritis patients from the community treated with methotrexate or leflunomide: results from the ESPOIR cohort

Bruno Fautrel, Benjamin Granger, Bernard Combe, Alain Saraux, Francis Guillemin, Xavier Le Loet Arthritis Research & Therapy 2012, 14:R249 (19 November 2012)

Abstract | Full text | PDF | PubMed

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