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High-density lipoprotein cholesterol subfractions HDL2 and HDL3 are reduced in women with rheumatoid arthritis and may augment the cardiovascular risk of women with RA: a cross-sectional study
Elke Arts, Jaap Fransen, Heidi Lemmers, Anton Stalenhoef, Leo Joosten, Piet van Riel, Calin D Popa Arthritis Research & Therapy 2012, 14:R116 (14 May 2012)
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Body mass index influences the response to infliximab in ankylosing spondylitis
Sébastien Ottaviani, Yannick Allanore, Florence Tubach, Marine Forien, Anaïs Gardette, Blandine Pasquet, Elisabeth Palazzo, Marine Meunier, Gilles Hayem, Chantal Job-Deslandre, André Kahan, Olivier Meyer, Philippe Dieudé Arthritis Research & Therapy 2012, 14:R115 (14 May 2012)
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Elevated levels of fibrinogen-derived endogenous citrullinated peptides in synovial fluid of rheumatoid arthritis patients
Reinout Raijmakers, Joyce JBC van Beers, Mahmoud El-Azzouny, Natasja FC Visser, Borut Božič, Ger JM Pruijn, Albert JR Heck Arthritis Research & Therapy 2012, 14:R114 (14 May 2012)
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Increased type II collagen cleavage by cathepsin K and collagenase activities with aging and osteoarthritis in human articular cartilage
Valeria M Dejica, John S Mort, Sheila Laverty, John Antoniou, David J Zukor, Michael Tanzer, A Robin Poole Arthritis Research & Therapy 2012, 14:R113 (14 May 2012)
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Low-dose oral prednisone improves clinical and ultrasonographic remission rates in early rheumatoid arthritis: results of a 12-month open-label randomised study
Carlomaurizio Montecucco, Monica Todoerti, Garifallia Sakellariou, Carlo Scirè, Roberto Caporali Arthritis Research & Therapy 2012, 14:R112 (14 May 2012)
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Resistin in idiopathic inflammatory myopathies
Mária Filková, Hana Hulejová, Klára Kuncová, Lenka Pleštilová, Lucie Cerezo, Heřman Mann, Martin Klein, Josef Zámečník, Steffen Gay, Jiří Vencovský, Ladislav Šenolt Arthritis Research & Therapy 2012, 14:R111 (11 May 2012)
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Mycophenolic acid counteracts B cell proliferation and plasmablast formation in patients with systemic lupus erythematosus
Sebastian Eickenberg, Eva Mickholz, Elisabeth Jung, Jerzy-Roch Nofer, Herrmann Pavenstädt, Annett M Jacobi Arthritis Research & Therapy 2012, 14:R110 (9 May 2012)
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Long-term stability of anti-cyclic citrullinated peptide antibody status in patients with early inflammatory polyarthritis
Marian L Burr, Sebastien Viatte, Marwan Bukhari, Darren Plant, Deborah P Symmons, Wendy Thomson, Anne Barton Arthritis Research & Therapy 2012, 14:R109 (9 May 2012)
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Nothing lasts forever - a critical look at sustained remission
Daniel Aletaha Arthritis Research & Therapy 2012, 14:116 (9 May 2012)
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Osteoporosis in ankylosing spondylitis - prevalence, risk factors and methods of assessment
Eva Klingberg, Mattias Lorentzon, Dan Mellström, Mats Geijer, Jan Göthlin, Elisabet Hilme, Martin Hedberg, Hans Carlsten, Helena Forsblad-d'Elia Arthritis Research & Therapy 2012, 14:R108 (8 May 2012)
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Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis
Masaru Kimata, David L Cullins, Monica L Brown, David D Brand, Edward F Rosloniec, Linda K Myers, John M Stuart, Andrew H Kang Arthritis Research & Therapy 2012, 14:R107 (8 May 2012)
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Efficacy of an immunotoxin to folate receptor beta in the intra-articular treatment of antigen-induced arthritis
Taku Nagai, Akira Kyo, Kazuhisa Hasui, Sonshin Takao, Takami Matsuyama Arthritis Research & Therapy 2012, 14:R106 (2 May 2012)
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The effects of oxygen tension and antiaging factor Klotho on Wnt signaling in nucleus pulposus cells
Akihiko Hiyama, Fumiyuki Arai, Daisuke Sakai, Katsuya Yokoyama, Joji Mochida Arthritis Research & Therapy 2012, 14:R105 (2 May 2012)
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PAD4 is not essential for disease in the K/BxN murine autoantibody-mediated model of arthritis
Amanda S Rohrbach, Saskia Hemmers, Sanja Arandjelovic, Maripat Corr, Kerri A Mowen Arthritis Research & Therapy 2012, 14:R104 (2 May 2012)
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New insights into the role and mechanism of macrophage migration inhibitory factor in steroid-resistant patients with systemic lupus erythematosus
Fang-Fang Wang, Li-An Zhu, Yu-Qiong Zou, Hui Zheng, Alisa Wilson, Cheng-De Yang, Nan Shen, Daniel J Wallace, Michael H Weisman, Shun-Le Chen, Liang-Jing Lu Arthritis Research & Therapy 2012, 14:R103 (2 May 2012)
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Editor’s summary
Macrophage migration inhibitory factor (MIF) may play a role in the mechanism of steroid resistance in systemic lupus erythematosus by affecting the NF-κB/IκB signaling cascade, and is a potential therapeutic target.
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Inhibition of Th17 differentiation by anti-TNF-alpha therapy in uveitis patients with Behçet's disease
Sunao Sugita, Yuko Kawazoe, Ayano Imai, Yukiko Yamada, Shintaro Horie, Manabu Mochizuki Arthritis Research & Therapy 2012, 14:R99 (1 May 2012)
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Levels of adiponectin, a marker for PPAR-gamma activity, correlate with skin fibrosis in systemic sclerosis: potential utility as biomarker?
Katja Lakota, Jun Wei, Mary Carns, Monique Hinchcliff, Jungwha Lee, Michael L Whitfield, Snezna Sodin-Semrl, John Varga Arthritis Research & Therapy 2012, 14:R102 (1 May 2012)
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Sensory and sympathetic nerve fibers undergo sprouting and neuroma formation in the painful arthritic joint of geriatric mice
Juan M Jimenez-Andrade, Patrick W Mantyh Arthritis Research & Therapy 2012, 14:R101 (1 May 2012)
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Anti-type II collagen antibodies are associated with early radiographic destruction in rheumatoid arthritis
Mohammed Mullazehi, Marius C Wick, Lars Klareskog, Ronald van Vollenhoven, Johan Rönnelid Arthritis Research & Therapy 2012, 14:R100 (1 May 2012)
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The effect of three years of TNF alpha blocking therapy on markers of bone turnover and their predictive value for treatment discontinuation in patients with ankylosing spondylitis: a prospective longitudinal observational cohort study
Suzanne Arends, Anneke Spoorenberg, Pieternella M Houtman, Martha K Leijsma, Reinhard Bos, Cees GM Kallenberg, Henk Groen, Elisabeth Brouwer, Eveline van der Veer Arthritis Research & Therapy 2012, 14:R98 (30 April 2012)
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Anti-MJ/NXP-2 autoantibody specificity in a cohort of adult Italian patients with polymyositis/dermatomyositis
Angela Ceribelli, Micaela Fredi, Mara Taraborelli, Ilaria Cavazzana, Franco Franceschini, Marzia Quinzanini, Angela Tincani, Steven J Ross, Jason YF Chan, Brad A Pauley, Edward KL Chan, Minoru Satoh Arthritis Research & Therapy 2012, 14:R97 (30 April 2012)
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Interleukin-6 regulates anti-arthritic effect of methotrexate via reduction of SLC19A1 expression in a mouse arthritis model
Misato Hashizume, Hiroto Yoshida, Keisuke Tanaka, Miho Suzuki, Isao Matsumoto, Takayuki Sumida, Masahiko Mihara Arthritis Research & Therapy 2012, 14:R96 (30 April 2012)
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Editor’s summary
Interleukin-6 (IL-6) reduced the efficacy of methotrexate in a mouse arthritis model by inhibiting the expression of the reduced folate transporter SLC19A1, which is important for the uptake of methotrexate into cells.
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Progress in treatment of ANCA-associated vasculitis
Rona M Smith, Rachel B Jones, David RW Jayne Arthritis Research & Therapy 2012, 14:210 (30 April 2012)
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The interferon type I signature towards prediction of non-response to rituximab in rheumatoid arthritis patients
Hennie G Raterman, Saskia Vosslamber, Sander de Ridder, Michael T Nurmohamed, Willem F Lems, Maarten Boers, Mark van de Wiel, Ben AC Dijkmans, Cornelis L Verweij, Alexandre E Voskuyl Arthritis Research & Therapy 2012, 14:R95 (27 April 2012)
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Bias in effect size of systemic lupus erythematosus susceptibility loci across Europe: a case-control study
Elisa Alonso-Perez, Marian Suarez-Gestal, Manuel Calaza, Gian Sebastiani, Rudolf Pullmann, Chryssa Papasteriades, Attila Kovacs, Fotini N Skopouli, Marc Bijl, Ana Suarez, Maurizio Marchini, Sergio Migliaresi, Patricia Carreira, Josep Ordi-Ros, Torsten Witte, Sarka Ruzickova, Maria Santos, Nadia Barizzone, Francisco J Blanco, Bernard R Lauwerys, Juan J Gomez-Reino, Antonio Gonzalez, the European Consortium of SLE DNA Collections Arthritis Research & Therapy 2012, 14:R94 (27 April 2012)
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Synovial cytokine expression in psoriatic arthritis and associations with lymphoid neogenesis and clinical features
Raquel Celis, Núria Planell, José L Fernández-Sueiro, Raimon Sanmartí, Julio Ramírez, Isidoro González-Álvaro, José L Pablos, Juan D Cañete Arthritis Research & Therapy 2012, 14:R93 (27 April 2012)
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The renal urate transporter SLC17A1 locus: confirmation of association with gout
Jade E Hollis-Moffatt, Amanda J Phipps-Green, Brett Chapman, Gregory T Jones, Andre van Rij, Peter J Gow, Andrew A Harrison, John Highton, Peter B Jones, Grant W Montgomery, Lisa K Stamp, Nicola Dalbeth, Tony R Merriman Arthritis Research & Therapy 2012, 14:R92 (27 April 2012)
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Thrombin induces heme oxygenase-1 expression in human synovial fibroblasts through protease-activated receptor signaling pathways
Ju-Fang Liu, Sheng-Mou Hou, Chun-Hao Tsai, Chun-Yin Huang, Wei-Hung Yang, Chih-Hsin Tang Arthritis Research & Therapy 2012, 14:R91 (27 April 2012)
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Role of non-immune mechanisms of muscle damage in idiopathic inflammatory myopathies
William Coley, Sree Rayavarapu, Kanneboyina Nagaraju Arthritis Research & Therapy 2012, 14:209 (27 April 2012)
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Statins accelerate the onset of collagen type II-induced arthritis in mice
Rob J Vandebriel, Hilda JI De Jong, Eric R Gremmer, Olaf H Klungel, Jan-Willem Tervaert, Wout Slob, Jan Willem Van Der Laan, Henk Van Loveren Arthritis Research & Therapy 2012, 14:R90 (26 April 2012)
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Smoking interacts with HLA-DRB1 shared epitope in the development of anti-citrullinated protein antibody-positive rheumatoid arthritis: results from the Malaysian Epidemiological Investigation of Rheumatoid Arthritis (MyEIRA)
Chun Too, Abqariyah Yahya, Shahnaz Murad, Jasbir Dhaliwal, Per Larsson, Nor Muhamad, Nor Abdullah, Amal Mustafa, Lars Klareskog, Lars Alfredsson, Leonid Padyukov, Camilla Bengtsson, MyEIRA study group Arthritis Research & Therapy 2012, 14:R89 (26 April 2012)
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Congenital heart block: evidence for a pathogenic role of maternal autoantibodies
Aurélie Ambrosi, Marie Wahren-Herlenius Arthritis Research & Therapy 2012, 14:208 (26 April 2012)
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Suppression of endothelial cell activity by inhibition of TNFα
Qiang Shu, Mohammad A Amin, Jeffrey H Ruth, Phillip L Campbell, Alisa E Koch Arthritis Research & Therapy 2012, 14:R88 (25 April 2012)
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The Sp1 transcription factor is essential for the expression of gliostatin/thymidine phosphorylase in rheumatoid fibroblast-like synoviocytes
Kenji Ikuta, Yuko Waguri-Nagaya, Kae Kikuchi, Takaya Yamagami, Masahiro Nozaki, Mineyoshi Aoyama, Kiyofumi Asai, Takanobu Otsuka Arthritis Research & Therapy 2012, 14:R87 (25 April 2012)
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Serum BAFF and APRIL levels in patients with IgG4-related disease and their clinical significance
Kazuhiro Kiyama, Daisuke Kawabata, Yuji Hosono, Koji Kitagori, Naoichiro Yukawa, Hajime Yoshifuji, Koichiro Omura, Takao Fujii, Tsuneyo Mimori Arthritis Research & Therapy 2012, 14:R86 (24 April 2012)
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A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis
Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper C Broen, Madelon C Vonk, Raquel Ríos-Fernández, Gerard Espinosa, Patricia Carreira, María T Camps, Maria J Castillo, Miguel A González-Gay, Emma Beltrán, María Carmen Freire, Javier Narváez, Carlos Tolosa, Torsten Witte, Alexander Kreuter, Annemie J Schuerwegh, Anna-Maria Hoffmann-Vold, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Meng Chee, Ariane Herrick, Bobby PC Koeleman, Christopher P Denton, Carmen Fonseca, Timothy RDJ Radstake, Javier Martin, the Spanish Scleroderma Group et al.
Arthritis Research & Therapy 2012, 14:R85 (24 April 2012)
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MRI and X-ray in axial spondyloarthritis: the relationship between inflammatory and structural changes
Walter P Maksymowych Arthritis Research & Therapy 2012, 14:207 (19 April 2012)
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Identification of low-frequency TRAF3IP2 coding variants in psoriatic arthritis patients and functional characterization
Beate Böhm, Harald Burkhardt, Steffen Uebe, Maria Apel, Frank Behrens, André Reis, Ulrike Hüffmeier Arthritis Research & Therapy 2012, 14:R84 (18 April 2012)
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Risk of end-stage renal disease associated with gout: a nationwide population study
Kuang-Hui Yu, Chang-Fu Kuo, Shue-Fen Luo, Lai-Chu See, I-Jun Chou, Hsiao-Chun Chang, Meng-Jiun Chiou Arthritis Research & Therapy 2012, 14:R83 (18 April 2012)
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Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes
Ioanna Papathanasiou, Konstantinos N Malizos, Aspasia Tsezou Arthritis Research & Therapy 2012, 14:R82 (18 April 2012)
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Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study
Ying Chen, Peter T Dawes, Jon C Packham, Derek L Mattey Arthritis Research & Therapy 2012, 14:R81 (18 April 2012)
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Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus
Shui-Lian Yu, Paul KS Chan, Chun-Kwok Wong, Cheuk-Chun Szeto, Suzanne C Ho, Karine So, May MY Yu, So-Fan Yim, Tak-Hong Cheung, Martin CS Wong, Jo LK Cheung, Apple CM Yeung, Edmund K Li, Lai-Shan Tam Arthritis Research & Therapy 2012, 14:R80 (18 April 2012)
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Autoantibodies to transcription intermediary factor (TIF)1β associated with dermatomyositis
Minoru Satoh, Jason YF Chan, Steven J Ross, Yi Li, Yoshioki Yamasaki, Hidehiro Yamada, Monica Vazquez-del Mercado, Marcelo H Petri, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Reyes, Eric S Sobel, Westley H Reeves, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:R79 (18 April 2012)
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Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis
Kyle D Allen, Brian A Mata, Mostafa A Gabr, Janet L Huebner, Samuel B Adams, Virginia B Kraus, Daniel O Schmitt, Lori A Setton Arthritis Research & Therapy 2012, 14:R78 (17 April 2012)
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Circulating and synovial antibody profiling of juvenile arthritis patients by nucleic acid programmable protein arrays
David S Gibson, Ji Qiu, Eliseo A Mendoza, Kristi Barker, Madeleine E Rooney, Joshua LaBaer Arthritis Research & Therapy 2012, 14:R77 (17 April 2012)
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Estradiol ameliorates arthritis and protects against systemic bone loss in Staphylococcus aureus infection in mice
Inger Gjertsson, Marie K Lagerquist, Erik Kristiansson, Hans Carlsten, Catharina Lindholm Arthritis Research & Therapy 2012, 14:R76 (16 April 2012)
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miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4
Jing Li, Jingang Huang, Liming Dai, Degang Yu, Qian Chen, Xiaoling Zhang, Kerong Dai Arthritis Research & Therapy 2012, 14:R75 (16 April 2012)
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Editor’s summary
The microRNA miR-146a may reduce cellular response to transforming growth factor-beta through targeted inhibition of Smad4 in cartilage, thus increasing vascular endothelial growth factor levels, and increasing chondrocyte apoptosis.
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Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis
Carmen A Ambarus, Troy Noordenbos, Maria JH de Hair, Paul P Tak, Dominique LP Baeten Arthritis Research & Therapy 2012, 14:R74 (11 April 2012)
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Increased frequency of CCR4+ and CCR6+ memory T-cells including CCR7+CD45RAmed very early memory cells in granulomatosis with polyangiitis (Wegener's)
Ursula Fagin, Silke Pitann, Wolfgang L Gross, Peter Lamprecht Arthritis Research & Therapy 2012, 14:R73 (10 April 2012)
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Induction of superficial zone protein (SZP)/lubricin/PRG 4 in muscle-derived mesenchymal stem/progenitor cells by transforming growth factor-β1 and bone morphogenetic protein-7
José A Andrades, Shirley C Motaung, Pedro Jiménez-Palomo, Silvia Claros, José M López-Puerta, José Becerra, Thomas M Schmid, A Hari Reddi Arthritis Research & Therapy 2012, 14:R72 (10 April 2012)
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Correction: FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development
Rizwanul Haque, Fengyang Lei, Xiaofang Xiong, Yuzhang Wu, Jianxun Song Arthritis Research & Therapy 2012, 14:401 (10 April 2012)
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Knotting the NETs: Analyzing histone modifications in neutrophil extracellular traps
Indira Neeli, Marko Radic Arthritis Research & Therapy 2012, 14:115 (6 April 2012)
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Bone formation rather than inflammation reflects Ankylosing Spondylitis activity on PET-CT: a pilot study
Stefan TG Bruijnen, Mignon AC van der Weijden, Joannes P Klein, Otto S Hoekstra, Ronald Boellaard, J Christiaan van Denderen, Ben AC Dijkmans, Alexandre E Voskuyl, Irene E van der Horst-Bruinsma, Conny J van der Laken Arthritis Research & Therapy 2012, 14:R71 (2 April 2012)
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Placebo analgesia: cognitive influences on therapeutic outcome
Alison Watson, Andrea Power, Christopher Brown, Wael El-Deredy, Anthony Jones Arthritis Research & Therapy 2012, 14:206 (30 March 2012)
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What is the future of CCR5 antagonists in rheumatoid arthritis?
Tsutomu Takeuchi, Hideto Kameda Arthritis Research & Therapy 2012, 14:114 (30 March 2012)
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Replication study confirms the association between UBAC2 and Behçet's disease in two independent Chinese sets of patients and controls
Shengping Hou, Qinmeng Shu, Zhengxuan Jiang, Yuanyuan Chen, Fuzhen Li, Feilan Chen, Aize Kijlstra, Peizeng Yang Arthritis Research & Therapy 2012, 14:R70 (29 March 2012)
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Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes
Sarah-Salwa Nebbaki, Fatima El Mansouri, Hassan Afif, Mohit Kapoor, Mohamed Benderdour, Nicolas Duval, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Hassan Fahmi Arthritis Research & Therapy 2012, 14:R69 (28 March 2012)
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Meryl Streep and the problems of clinical trials
David A Isenberg Arthritis Research & Therapy 2012, 14:113 (23 March 2012)
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Sustained rheumatoid arthritis remission is uncommon in clinical practice
Femke HM Prince, Vivian P Bykerk, Nancy A Shadick, Bing Lu, Jing Cui, Michelle Frits, Christine K Iannaccone, Michael E Weinblatt, Daniel H Solomon Arthritis Research & Therapy 2012, 14:R68 (19 March 2012)
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Editor’s summary
In clinical practice only a minority of patients with rheumatoid arthritis (RA) are in sustained remission, suggesting strict monitoring is required even once remission is reached.
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Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: a cross-sectional study
Ahmed Solomon, Gavin R Norton, Angela J Woodiwiss, Patrick H Dessein Arthritis Research & Therapy 2012, 14:R67 (19 March 2012)
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Effect of pregnancy on serum cytokines in SLE patients
Andrea Doria, Maurizio Cutolo, Anna Ghirardello, Margherita Zen, Danilo Villalta, Angela Tincani, Leonardo Punzi, Luca Iaccarino, Michelle Petri Arthritis Research & Therapy 2012, 14:R66 (14 March 2012)
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Functional role of IL-22 in psoriatic arthritis
Anupam Mitra, Smriti K Raychaudhuri, Siba P Raychaudhuri Arthritis Research & Therapy 2012, 14:R65 (14 March 2012)
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TLR2 ligation induces the production of IL-23/IL-17 via IL-6, STAT3 and NF-kB pathway in patients with primary Sjogren's syndrome
Seung-Ki Kwok, Mi-La Cho, Yang-Mi Her, Hye-Joa Oh, Mi-Kyung Park, Seon-Yeong Lee, Yun Woo, Ji Ju, Kyung-Su Park, Ho-Youn Kim, Sung-Hwan Park Arthritis Research & Therapy 2012, 14:R64 (14 March 2012)
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Clinical features of symptomatic patellofemoral joint osteoarthritis
George Peat, Rachel C Duncan, Laurence RJ Wood, Elaine Thomas, Sara Muller Arthritis Research & Therapy 2012, 14:R63 (14 March 2012)
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TNFα modulates protein degradation pathways in rheumatoid arthritis synovial fibroblasts
Alison M Connor, Nizar Mahomed, Rajiv Gandhi, Edward C Keystone, Stuart A Berger Arthritis Research & Therapy 2012, 14:R62 (14 March 2012)
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Value of self-performed joint counts in rheumatoid arthritis patients near remission
Helga Radner, Johannes Grisar, Josef S Smolen, Tanja Stamm, Daniel Aletaha Arthritis Res Ther 2012, 14:R61 (14 March 2012)
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HMGB1: a smoking gun in lupus nephritis?
David S Pisetsky Arthritis Research & Therapy 2012, 14:112 (14 March 2012)
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Cytokines profiling by multiplex analysis in experimental arthritis: which pathophysiological relevance for articular versus systemic mediators?
Joseph Paquet, Jean-Christophe Goebel, Camille Delaunay, Astrid Pinzano, Laurent Grossin, Christel Cournil-Henrionnet, Pierre Gillet, Patrick Netter, Jean-Yves Jouzeau, David Moulin Arthritis Research & Therapy 2012, 14:R60 (13 March 2012)
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Inhibition of inflammation but not ankylosis by glucocorticoids in mice: further evidence for the entheseal stress hypothesis
Kirsten Braem, Christophe M Deroose, Frank P Luyten, Rik J Lories Arthritis Research & Therapy 2012, 14:R59 (12 March 2012)
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Characterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate
Cécile Lambert, Marianne Mathy-Hartert, Jean-Emile Dubuc, Eulàlia Montell, Josep Vergés, Carine Munaut, Agnès Noël, Yves Henrotin Arthritis Research & Therapy 2012, 14:R58 (12 March 2012)
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Induction of long-term B-cell depletion in refractory rheumatoid arthritis patients preferentially affects autoreactive more than protective humoral immunity
YK Onno Teng, Gillian Wheater, Vanessa E Hogan, Philip Stocks, EW Nivine Levarht, Tom WJ Huizinga, Rene EM Toes, Jacob M van Laar Arthritis Research & Therapy 2012, 14:R57 (12 March 2012)
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Implication of new atherosclerotic carotid plaques in the cardiovascular outcome of patients with rheumatoid arthritis
Miguel A González-Gay, Carlos González-Juanatey Arthritis Research & Therapy 2012, 14:105 (12 March 2012)
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The independent association between parathyroid hormone levels and hyperuricemia: a national population study
Janet Y Hui, Jee Woong J Choi, David B Mount, Yanyan Zhu, Yuqing Zhang, Hyon K Choi Arthritis Research & Therapy 2012, 14:R56 (10 March 2012)
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A systematic critical review on MRI in spondyloarthritis
Bodil Arnbak, Charlotte Leboeuf-Yde, Tue Jensen Arthritis Research & Therapy 2012, 14:R55 (9 March 2012)
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The anti-CD74 humanized monoclonal antibody, milatuzumab, which targets the invariant chain of MHC II complexes, alters B-cell proliferation, migration, and adhesion molecule expression
Daniela Frölich, Daniela Blaβfeld, Karin Reiter, Claudia Giesecke, Capucine Daridon, Henrik E Mei, Gerd R Burmester, David M Goldenberg, Abdulagabar Salama, Thomas Dörner Arthritis Research & Therapy 2012, 14:R54 (9 March 2012)
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Is IL-6 an appropriate target to treat spondyloarthritis patients refractory to anti-TNF therapy? a multicentre retrospective observational study
Fernando Lekpa, Cécile Poulain, Daniel Wendling, Martin Soubrier, Michel De Bandt, Jean Berthelot, Philippe Gaudin, Eric Toussirot, Philippe Goupille, Thao Pham, Jérémie Sellam, Rémy Bruckert, Muriel Paul, Valérie Farrenq, Pascal Claudepierre, the Club Rhumatismes et Inflammation Arthritis Research & Therapy 2012, 14:R53 (9 March 2012)
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Moving instead of asking? Performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis
Salima FE van Weely, J Christiaan van Denderen, Martijn PM Steultjens, Marike van der Leeden, Michael T Nurmohamed, Joost Dekker, Ben AC Dijkmans, Irene E van der Horst-Bruinsma Arthritis Research & Therapy 2012, 14:R52 (8 March 2012)
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Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration
Takashi Yurube, Toru Takada, Teppei Suzuki, Kenichiro Kakutani, Koichiro Maeno, Minoru Doita, Masahiro Kurosaka, Kotaro Nishida Arthritis Research & Therapy 2012, 14:R51 (6 March 2012)
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Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis
Marie Hudson, Janet Pope, Michael Mahler, Solène Tatibouet, Russell Steele, Murray Baron, Canadian Scleroderma Research Group (CSRG), Marvin J Fritzler Arthritis Research & Therapy 2012, 14:R50 (6 March 2012)
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Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage
Girish Ramaswamy, Philip Sohn, Alan Eberhardt, Rosa Serra Arthritis Research & Therapy 2012, 14:R49 (6 March 2012)
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Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity
Fumihito Suzuki, Tetsuo Kubota, Yasunari Miyazaki, Kinya Ishikawa, Masashi Ebisawa, Shunsei Hirohata, Takashi Ogura, Hidehiro Mizusawa, Toshio Imai, Nobuyuki Miyasaka, Toshihiro Nanki Arthritis Research & Therapy 2012, 14:R48 (6 March 2012)
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Dutch translation and cross-cultural adaptation of the PROMIS® physical function item bank and cognitive pre-test in Dutch arthritis patients
Martijn AH Oude Voshaar, Peter M ten Klooster, Erik Taal, Eswar Krishnan, Mart AFJ van de Laar Arthritis Research & Therapy 2012, 14:R47 (5 March 2012)
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Editor’s summary
The Patient-Reported Outcomes Measurement Information System (PROMIS) physical function item bank translated into Dutch is semantically and conceptually equivalent to the original, with all items comprehended by patients as intended.
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Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study
Johanna T Gustafsson, Julia F Simard, Iva Gunnarsson, Kerstin Elvin, Ingrid E Lundberg, Lars-Olof Hansson, Anders Larsson, Elisabet Svenungsson Arthritis Research & Therapy 2012, 14:R46 (5 March 2012)
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Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes
Chiyoko Sekine, Akemi Koyanagi, Noriko Koyama, Katsuto Hozumi, Shigeru Chiba, Hideo Yagita Arthritis Research & Therapy 2012, 14:R45 (5 March 2012)
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Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study
Evangelia Zampeli, Athanase Protogerou, Kimon Stamatelopoulos, Kalliopi Fragiadaki, Christina G Katsiari, Katerina Kyrkou, Christos M Papamichael, Myron Mavrikakis, Peter Nightingale, George D Kitas, Petros P Sfikakis Arthritis Research & Therapy 2012, 14:R44 (5 March 2012)
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Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis
Altan Ercan, Jing Cui, Melissa M Hazen, Franak Batliwalla, Louise Royle, Pauline M Rudd, Jonathan S Coblyn, Nancy Shadick, Michael E Weinblatt, Peter Gregersen, David M Lee, Peter A Nigrovic Arthritis Research & Therapy 2012, 14:R43 (5 March 2012)
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Plasma proteins take their toll on the joint in osteoarthritis
Steven R Goldring, Carla R Scanzello Arthritis Research & Therapy 2012, 14:111 (5 March 2012)
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The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis
Raquel López-Mejías, Carlos González-Juanatey, Mercedes García-Bermúdez, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Javier Llorca, Javier Martín, Miguel A González-Gay Arthritis Research & Therapy 2012, 14:R42 (1 March 2012)
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Taking responsibility for the early assessment and treatment of patients with musculoskeletal pain: a review and critical analysis
Nadine E Foster, Jan Hartvigsen, Peter R Croft Arthritis Research & Therapy 2012, 14:205 (29 February 2012)
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Clinical examination or whole-body magnetic resonance imaging: the Holy Grail of spondyloarthritis imaging
Winston J Rennie Arthritis Research & Therapy 2012, 14:110 (29 February 2012)
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Role of environmental factors in autoantibody production - importance of a detailed analysis in a small cohort
Minoru Satoh, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:109 (29 February 2012)
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Inhibiting citrullination in rheumatoid arthritis: taking fuel from the fire
Benjamin AC Fisher, Patrick J Venables Arthritis Research & Therapy 2012, 14:108 (29 February 2012)
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Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study
Berit M Sverdrup, Henrik Källberg, Lars Klareskog, Lars Alfredsson, Epidemiological Investigation of Rheumatoid Arthritis Study Group Arthritis Research & Therapy 2012, 14:R41 (28 February 2012)
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Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndrome
Hongen Yin, Cuong Q Nguyen, Yuval Samuni, Toshimitsu Uede, Ammon B Peck, John A Chiorini Arthritis Research & Therapy 2012, 14:R40 (27 February 2012)
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Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study
Jon T Giles, Justyna Fert-Bober, Jin Park, Clifton O Bingham, Felipe Andrade, Karen Fox-Talbot, Dimitrios Pappas, Antony Rosen, Jennifer van Eyk, Joan M Bathon, Marc K Halushka Arthritis Research & Therapy 2012, 14:R39 (24 February 2012)
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The BRIC-GARN Meeting 2011: of mice and men
David S Pisetsky Arthritis Research & Therapy 2012, 14:107 (24 February 2012)
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How does BAFF activate B cells in patients with autoimmune diseases?
Xavier Mariette Arthritis Research & Therapy 2012, 14:106 (24 February 2012)
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Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-Terminal kinase pathway
Sang-il Lee, David L Boyle, Andres Berdeja, Gary S Firestein Arthritis Research & Therapy 2012, 14:R38 (21 February 2012)
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Abatacept versus other biologics in methotrexate inadequate responders with rheumatoid arthritis: you like tomato and I like tomahto... let's call the whole thing off
Yusuf Yazici Arthritis Research & Therapy 2012, 14:104 (21 February 2012)
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Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus
Erik A Korte, Patrick M Gaffney, David W Powell Arthritis Research & Therapy 2012, 14:204 (20 February 2012)
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