Arthritis Research & Therapy

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		Research article The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells Betty Y Chang, Min Huang, Michelle Francesco, Jun Chen, Jeremy Sokolove, Padmaja Magadala, William H Robinson, Joseph J Buggy Arthritis Research & Therapy 2011, 13:R115 (13 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review The lung as a possible target for the immune reaction in myositis Sonye K Danoff, Livia Casciola-Rosen Arthritis Research & Therapy 2011, 13:230 (13 July 2011) Abstract \| Full text \| PDF \| PubMed
		Review MicroRNAs in systemic rheumatic diseases Angela Ceribelli, Bing Yao, Paul R Dominguez-Gutierrez, Md A Nahid, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2011, 13:229 (13 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Characterization of a novel and spontaneous mouse model of inflammatory arthritis Iris A Adipue, Joel T Wilcox, Cody King, Carolyn AY Rice, Katherine M Shaum, Cory M Suard, Elri Brink, Stephen D Miller, Eileen J McMahon Arthritis Research & Therapy 2011, 13:R114 (12 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1 Yu-Jung Heo, Hye-Jwa Oh, Young Jung, Mi-La Cho, Seon-Yeong Lee, Jun-Geol Yu, Mi-Kyung Park, Hae-Rim Kim, Sang-Heon Lee, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2011, 13:R113 (12 July 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label Cándido Díaz-Lagares, Roberto Pérez-Alvarez, Francisco J García-Hernández, María M Ayala-Gutiérrez, José Callejas, Agustín Martínez-Berriotxoa, Javier Rascón, Luis Caminal-Montero, Albert Selva-O'Callaghan, Joaquim Oristrell, Carmen Hidalgo, Ricardo Gómez-de-la-Torre, Luis Sáez, Jesús Canora-Lebrato, María-Teresa Camps, Norberto Ortego-Centeno, María-Jesús Castillo-Palma, Manuel Ramos-Casals, the BIOGEAS Study Group Arthritis Research & Therapy 2011, 13:R112 (11 July 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis Fulvia Ceccarelli, Carlo Perricone, Martina Fabris, Cristiano Alessandri, Annamaria Iagnocco, Cinzia Fabro, Elena Pontarini, Salvatore De Vita, Guido Valesini Arthritis Research & Therapy 2011, 13:R111 (8 July 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain Michael Boettger, Diana Kümmel, Andrew Harrison, Hans-Georg Schaible Arthritis Research & Therapy 2011, 13:R110 (7 July 2011) Abstract \| Full text \| PDF \| PubMed
		Review Cytokine disturbances in systemic lupus erythematosus Noam Jacob, William Stohl Arthritis Research & Therapy 2011, 13:228 (6 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Disturbance of cytokine networks in Sjögren's syndrome Pierre Youinou, Jacques-Olivier Pers Arthritis Research & Therapy 2011, 13:227 (6 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Commentary Neutrophils and interferon-α-producing cells: who produces interferon in lupus? Patrice Decker Arthritis Research & Therapy 2011, 13:118 (6 July 2011) Abstract \| Full text \| PDF \| PubMed
		Review Liver involvement in subjects with rheumatic disease Carlo Selmi, Maria De Santis, M Eric Gershwin Arthritis Research & Therapy 2011, 13:226 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Review Cardiovascular co-morbidity in patients with rheumatic diseases Johan Frostegård Arthritis Research & Therapy 2011, 13:225 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Review Conditions in subjects with rheumatic diseases: pulmonary manifestations of vasculitides Julia U Holle, Frank Moosig, Klaus Dalhoff, Wolfgang L Gross Arthritis Research & Therapy 2011, 13:224 (30 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Fibromyalgia, myofascial pain, tender points and trigger points: splitting or lumping? Robert M Bennett, Don L Goldenberg Arthritis Research & Therapy 2011, 13:117 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects Kaspar R Nielsen, Rudi Steffensen, Martin Boegsted, John Baech, Soeren Lundbye-Christensen, Merete L Hetland, Sophine B Krintel, Hans E Johnsen, Mette Nyegaard, Julia S Johansen Arthritis Research & Therapy 2011, 13:R109 (29 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis George S Metsios, Antonios Stavropoulos-Kalinoglou, Gareth J Treharne, Alan M Nevill, Aamer Sandoo, Vasileios F Panoulas, Tracey E Toms, Yiannis Koutedakis, George D Kitas Arthritis Research & Therapy 2011, 13:R108 (29 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Physical activity and disease activity are important predictors of hospital admissions and length of hospitalisation in rheumatoid arthritis patients, suggesting lifestyle changes combined with effective pharmacological therapy may improve health and economic outcomes.
		Review Treating rheumatic patients with a malignancy Katarzyna Elandt, Daniel Aletaha Arthritis Research & Therapy 2011, 13:223 (29 June 2011) Abstract \| Full text \| PDF \| PubMed
		Review Renal co-morbidity in patients with rheumatic diseases Hans-Joachim Anders, Volker Vielhauer Arthritis Research & Therapy 2011, 13:222 (29 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Considering comorbidity in managing rheumatic diseases: going where trials cannot go Daniel Aletaha, Thomas Dörner Arthritis Research & Therapy 2011, 13:116 (29 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach Alexis Régent, Hanadi Dib, Kim H Ly, Christian Agard, Mathieu C Tamby, Nicolas Tamas, Babette Weksler, Christian Federici, Cédric Broussard, Loïc Guillevin, Luc Mouthon Arthritis Research & Therapy 2011, 13:R107 (28 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Defective response of CD4⁺T cells to retinoic acid and TGFβ in systemic lupus erythematosus Eric S Sobel, Todd M Brusko, Ed J Butfiloski, Wei Hou, Shiwu Li, Carla M Cuda, Ariana N Abid, Westley H Reeves, Laurence Morel Arthritis Research & Therapy 2011, 13:R106 (27 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases Emilie Ducourau, Denis Mulleman, Gilles Paintaud, Delphine Miow Lin, Francine Lauféron, David Ternant, Hervé Watier, Philippe Goupille Arthritis Research & Therapy 2011, 13:R105 (27 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary High initial serum concentration of infliximab reduces the development of antibodies towards infliximab (ATI) and absence of ATI may be associated with prolonged maintenance of infliximab, suggesting infliximab serum concentrations should be monitored early.
		Research article Potential role and mechanism of IFN-gamma inducible protein-10 on receptor activator of nuclear factor kappa-B ligand (RANKL) expression in rheumatoid arthritis Eun Lee, MiRan Seo, Yong-Sung Juhnn, Jeong Kim, Yoo Hong, Yun Lee, Eun Lee, Yeong Song Arthritis Research & Therapy 2011, 13:R104 (27 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts Wenhua Zhu, Liesu Meng, Congshan Jiang, Xiaojing He, Weikun Hou, Peng Xu, Heng Du, Rikard Holmdahl, Shemin Lu Arthritis Research & Therapy 2011, 13:R103 (27 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

	All
		Research article The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells Betty Y Chang, Min Huang, Michelle Francesco, Jun Chen, Jeremy Sokolove, Padmaja Magadala, William H Robinson, Joseph J Buggy Arthritis Research & Therapy 2011, 13:R115 (13 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review The lung as a possible target for the immune reaction in myositis Sonye K Danoff, Livia Casciola-Rosen Arthritis Research & Therapy 2011, 13:230 (13 July 2011) Abstract \| Full text \| PDF \| PubMed
		Review MicroRNAs in systemic rheumatic diseases Angela Ceribelli, Bing Yao, Paul R Dominguez-Gutierrez, Md A Nahid, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2011, 13:229 (13 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Characterization of a novel and spontaneous mouse model of inflammatory arthritis Iris A Adipue, Joel T Wilcox, Cody King, Carolyn AY Rice, Katherine M Shaum, Cory M Suard, Elri Brink, Stephen D Miller, Eileen J McMahon Arthritis Research & Therapy 2011, 13:R114 (12 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1 Yu-Jung Heo, Hye-Jwa Oh, Young Jung, Mi-La Cho, Seon-Yeong Lee, Jun-Geol Yu, Mi-Kyung Park, Hae-Rim Kim, Sang-Heon Lee, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2011, 13:R113 (12 July 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label Cándido Díaz-Lagares, Roberto Pérez-Alvarez, Francisco J García-Hernández, María M Ayala-Gutiérrez, José Callejas, Agustín Martínez-Berriotxoa, Javier Rascón, Luis Caminal-Montero, Albert Selva-O'Callaghan, Joaquim Oristrell, Carmen Hidalgo, Ricardo Gómez-de-la-Torre, Luis Sáez, Jesús Canora-Lebrato, María-Teresa Camps, Norberto Ortego-Centeno, María-Jesús Castillo-Palma, Manuel Ramos-Casals, the BIOGEAS Study Group Arthritis Research & Therapy 2011, 13:R112 (11 July 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis Fulvia Ceccarelli, Carlo Perricone, Martina Fabris, Cristiano Alessandri, Annamaria Iagnocco, Cinzia Fabro, Elena Pontarini, Salvatore De Vita, Guido Valesini Arthritis Research & Therapy 2011, 13:R111 (8 July 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain Michael Boettger, Diana Kümmel, Andrew Harrison, Hans-Georg Schaible Arthritis Research & Therapy 2011, 13:R110 (7 July 2011) Abstract \| Full text \| PDF \| PubMed
		Review Cytokine disturbances in systemic lupus erythematosus Noam Jacob, William Stohl Arthritis Research & Therapy 2011, 13:228 (6 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Disturbance of cytokine networks in Sjögren's syndrome Pierre Youinou, Jacques-Olivier Pers Arthritis Research & Therapy 2011, 13:227 (6 July 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Commentary Neutrophils and interferon-α-producing cells: who produces interferon in lupus? Patrice Decker Arthritis Research & Therapy 2011, 13:118 (6 July 2011) Abstract \| Full text \| PDF \| PubMed
		Review Liver involvement in subjects with rheumatic disease Carlo Selmi, Maria De Santis, M Eric Gershwin Arthritis Research & Therapy 2011, 13:226 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Review Cardiovascular co-morbidity in patients with rheumatic diseases Johan Frostegård Arthritis Research & Therapy 2011, 13:225 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Review Conditions in subjects with rheumatic diseases: pulmonary manifestations of vasculitides Julia U Holle, Frank Moosig, Klaus Dalhoff, Wolfgang L Gross Arthritis Research & Therapy 2011, 13:224 (30 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Fibromyalgia, myofascial pain, tender points and trigger points: splitting or lumping? Robert M Bennett, Don L Goldenberg Arthritis Research & Therapy 2011, 13:117 (30 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects Kaspar R Nielsen, Rudi Steffensen, Martin Boegsted, John Baech, Soeren Lundbye-Christensen, Merete L Hetland, Sophine B Krintel, Hans E Johnsen, Mette Nyegaard, Julia S Johansen Arthritis Research & Therapy 2011, 13:R109 (29 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis George S Metsios, Antonios Stavropoulos-Kalinoglou, Gareth J Treharne, Alan M Nevill, Aamer Sandoo, Vasileios F Panoulas, Tracey E Toms, Yiannis Koutedakis, George D Kitas Arthritis Research & Therapy 2011, 13:R108 (29 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Physical activity and disease activity are important predictors of hospital admissions and length of hospitalisation in rheumatoid arthritis patients, suggesting lifestyle changes combined with effective pharmacological therapy may improve health and economic outcomes.
		Review Treating rheumatic patients with a malignancy Katarzyna Elandt, Daniel Aletaha Arthritis Research & Therapy 2011, 13:223 (29 June 2011) Abstract \| Full text \| PDF \| PubMed
		Review Renal co-morbidity in patients with rheumatic diseases Hans-Joachim Anders, Volker Vielhauer Arthritis Research & Therapy 2011, 13:222 (29 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Considering comorbidity in managing rheumatic diseases: going where trials cannot go Daniel Aletaha, Thomas Dörner Arthritis Research & Therapy 2011, 13:116 (29 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach Alexis Régent, Hanadi Dib, Kim H Ly, Christian Agard, Mathieu C Tamby, Nicolas Tamas, Babette Weksler, Christian Federici, Cédric Broussard, Loïc Guillevin, Luc Mouthon Arthritis Research & Therapy 2011, 13:R107 (28 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Defective response of CD4⁺T cells to retinoic acid and TGFβ in systemic lupus erythematosus Eric S Sobel, Todd M Brusko, Ed J Butfiloski, Wei Hou, Shiwu Li, Carla M Cuda, Ariana N Abid, Westley H Reeves, Laurence Morel Arthritis Research & Therapy 2011, 13:R106 (27 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases Emilie Ducourau, Denis Mulleman, Gilles Paintaud, Delphine Miow Lin, Francine Lauféron, David Ternant, Hervé Watier, Philippe Goupille Arthritis Research & Therapy 2011, 13:R105 (27 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary High initial serum concentration of infliximab reduces the development of antibodies towards infliximab (ATI) and absence of ATI may be associated with prolonged maintenance of infliximab, suggesting infliximab serum concentrations should be monitored early.
		Research article Potential role and mechanism of IFN-gamma inducible protein-10 on receptor activator of nuclear factor kappa-B ligand (RANKL) expression in rheumatoid arthritis Eun Lee, MiRan Seo, Yong-Sung Juhnn, Jeong Kim, Yoo Hong, Yun Lee, Eun Lee, Yeong Song Arthritis Research & Therapy 2011, 13:R104 (27 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts Wenhua Zhu, Liesu Meng, Congshan Jiang, Xiaojing He, Weikun Hou, Peng Xu, Heng Du, Rikard Holmdahl, Shemin Lu Arthritis Research & Therapy 2011, 13:R103 (27 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central