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The role of the circadian clock in rheumatoid arthritis

Julie E Gibbs, David W Ray Arthritis Research & Therapy 2013, 15:205 (21 February 2013)

Abstract | Full text | PDF | PubMed

Research article   Open Access

IL-17-mediated Bcl-2 expression regulates survival of fibroblast-like synoviocytes in rheumatoid arthritis through STAT3 activation

Seon-Yeong Lee, Seung-Ki Kwok, Hye-Jin Son, Jun-Geol Ryu, Eun-Kyung Kim, Hye-Jwa Oh, Mi-La Cho, Ji Ju, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2013, 15:R31 (20 February 2013)

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Research article   Open Access

Clinical characteristics in subjects with NLRP3 V198M diagnosed at a single UK center and a review of the literature

Dorota M Rowczenio, Hadija Trojer, Tonia Russell, Anna Baginska, Thirusha Lane, Nicola M Stewart, Julian D Gillmore, Philip N Hawkins, Patricia Woo, Bozena Mikoluc, Helen J Lachmann Arthritis Research & Therapy 2013, 15:R30 (19 February 2013)

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Editorial   Free

The butterfly rash of lupus: An example of aposematism?

David S Pisetsky Arthritis Research & Therapy 2013, 15:106 (19 February 2013)

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Research article   Open Access

Cellular and extracellular matrix changes in anterior cruciate ligaments during human knee aging and osteoarthritis

Akihiko Hasegawa, Hiroyuki Nakahara, Mitsuo Kinoshita, Hiroshi Asahara, James Koziol, Martin K Lotz Arthritis Research & Therapy 2013, 15:R29 (14 February 2013)

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Research article   Open Access

MicroRNA-125b regulates the expression of aggrecanase-1 (ADAMTS-4) in human osteoarthritic chondrocytes

Tetsuya Matsukawa, Tadahiro Sakai, Tomo Yonezawa, Hideki Hiraiwa, Takashi Hamada, Motoshige Nakashima, Yohei Ono, Shinya Ishizuka, Hiroyuki Nakahara, Martin K Lotz, Hiroshi Asahara, Naoki Ishiguro Arthritis Research & Therapy 2013, 15:R28 (13 February 2013)

Abstract | Full text | PDF | PubMed | F1000 Biology

Research article   Open Access

Joint damage in rheumatoid arthritis: assessment of a new scoring method

Alexander Pfeil, Peter Oelzner, Klaus Bornholdt, Andreas Hansch, Gabriele Lehmann, Diane M Renz, Gunter Wolf, Joachim Böttcher Arthritis Research & Therapy 2013, 15:R27 (13 February 2013)

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Research article   Open Access

Regulatory effect of calcineurin inhibitor, tacrolimus, on IL-6/sIL-6R-mediated RANKL expression through JAK2-STAT3-SOCS3 signaling pathway in fibroblast-like synoviocytes

Jung-Yoon Choe, Ki-Yeun Park, Sung-Hoon Park, Sang-Il Lee, Seong-Kyu Kim Arthritis Research & Therapy 2013, 15:R26 (13 February 2013)

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Dendritic cells and the promise of antigen-specific therapy in rheumatoid arthritis

Ranjeny Thomas Arthritis Research & Therapy 2013, 15:204 (4 February 2013)

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Research article   Open Access

Rilonacept in the treatment of acute gouty arthritis: a randomized, controlled clinical trial using indomethacin as the active comparator

Robert A Terkeltaub, H Ralph Schumacher, John D Carter, Herbert SB Baraf, Robert R Evans, Jian Wang, Shirletta King-Davis, Steven P Weinstein Arthritis Research & Therapy 2013, 15:R25 (1 February 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Treatment with indomethacin alone in patients with acute gout flare is more effective than treatment with rilonacept and no greater pain relief is provided when used in combination with rilonacept. 

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Implantable sensor technology: measuring bone and joint biomechanics of daily life in vivo

Darryl D D'Lima, Benjamin J Fregly, Clifford W Colwell Arthritis Research & Therapy 2013, 15:203 (31 January 2013)

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Editorial   Free

Adult-onset immunodeficiency - why is it important in rheumatology?

Hans-Hartmut Peter Arthritis Research & Therapy 2012, 15:105 (30 January 2013)

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Research article   Open Access

Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation

Rowan S Hardy, Claudia Hülso, Yingling Liu, Sylvia J Gasparini, Colette Fong-Yee, Jinwen Tu, Shihani Stoner, Paul M Stewart, Karim Raza, Mark S Cooper, Markus J Seibel, Hong Zhou Arthritis Research & Therapy 2013, 15:R24 (29 January 2013)

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Gene expression profiling of early intervertebral disc degeneration reveals a down-regulation of canonical Wnt signaling and caveolin-1 expression: implications for development of regenerative strategies

Lucas A Smolders, Björn P Meij, David Onis, Frank M Riemers, Niklas Bergknut, Richard Wubbolts, Guy CM Grinwis, Martin Houweling, Marian JA Groot Koerkamp, Dik van Leenen, Frank CP Holstege, Herman AW Hazewinkel, Laura B Creemers, Louis C Penning, Marianna A Tryfonidou Arthritis Research & Therapy 2013, 15:R23 (29 January 2013)

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Research article   Open Access

Intra-articular delivery of adipose derived stromal cells attenuates osteoarthritis progression in an experimental rabbit model

Giovanna Desando, Carola Cavallo, Federica Sartoni, Lucia Martini, Annapaola Parrilli, Francesca Veronesi, Milena Fini, Roberto Giardino, Andrea Facchini, Brunella Grigolo Arthritis Research & Therapy 2013, 15:R22 (29 January 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Adipose derived stromal cells (ASC) promote repair of cartilage and inhibit progression of osteoarthritis (OA) in an experimental rabbit model, highlighting ASC therapy as a potential tool to treat OA.

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Dissecting complex epigenetic alterations in human lupus

Dipak R Patel, Bruce C Richardson Arthritis Research & Therapy 2012, 15:201 (29 January 2013)

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Research article   Open Access

High prevalence of spondyloarthritis and ankylosing spondylitis among familial Mediterranean fever patients and their first-degree relatives: further evidence for the connection

Servet Akar, Ozgul Soysal, Ali Balci, Dilek Solmaz, Vedat Gerdan, Fatos Onen, Mehmet Tunca, Nurullah Akkoc Arthritis Research & Therapy 2013, 15:R21 (28 January 2013)

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Editorial   Free

Tools for monitoring remission in rheumatoid arthritis: any will do, let's just pick one and start measuring

Yusuf Yazici, Ismail Simsek Arthritis Research & Therapy 2013, 15:104 (28 January 2013)

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Research article   Open Access

A rheumatoid factor paradox: inhibition of rituximab effector function

Jonathan D Jones, Irene Shyu, Marianna M Newkirk, William FC Rigby Arthritis Research & Therapy 2013, 15:R20 (25 January 2013)

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MicroRNA control in the development of systemic autoimmunity

Ruozhen Hu, Ryan M O'Connell Arthritis Research & Therapy 2013, 15:202 (25 January 2013)

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IgG4-related disease: why high IgG4 and fibrosis?

Takao Koike Arthritis Research & Therapy 2013, 15:103 (25 January 2013)

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CCN4 induces IL-6 production through αvβ5 receptor, PI3K, Akt, and NF-κB singling pathway in human synovial fibroblasts

Chun-Han Hou, Chih-Hsin Tang, Chin-Jung Hsu, Sheng-Mon Hou, Ju-Fang Liu Arthritis Research & Therapy 2013, 15:R19 (23 January 2013)

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Research article   Open Access

Plasma levels of osteopontin identify patients at risk for organ damage in systemic lupus erythematosus

Ornella J Rullo, Jennifer MP Woo, Miriam F Parsa, Alice DC Hoftman, Paul Maranian, David A Elashoff, Timothy B Niewold, Jennifer M Grossman, Bevra H Hahn, Maureen McMahon, Deborah K McCurdy, Betty P Tsao Arthritis Research & Therapy 2013, 15:R18 (23 January 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Impaired beta cell function is present in nondiabetic rheumatoid arthritis patients

Iván Ferraz-Amaro, Jose A García-Dopico, Lilian Medina-Vega, Miguel A González-Gay, Federico Díaz-González Arthritis Research & Therapy 2013, 15:R17 (22 January 2013)

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Research article   Open Access

Anti-cyclic citrullinated peptide antibody titer predicts time to rheumatoid arthritis onset in patients with undifferentiated arthritis: results from a 2-year prospective study

Nicola Bizzaro, Elena Bartoloni, Gabriella Morozzi, Stefania Manganelli, Valeria Riccieri, Paola Sabatini, Matteo Filippini, Marilina Tampoia, Antonella Afeltra, Giandomenico Sebastiani, Claudia Alpini, Vittorio Bini, Onelia Bistoni, Alessia Alunno, Roberto Gerli, the Forum Interdisciplinare per la Ricerca nelle Malattie Autoimmuni (FIRMA Group) Arthritis Research & Therapy 2013, 15:R16 (22 January 2013)

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Editorial   Free

Lots of autoantibodies equal lupus?

Martin Aringer, Edward Vital Arthritis Research & Therapy 2013, 15:102 (22 January 2013)

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Research article   Open Access

Expression of regulatory receptors on γδ T Cells and their cytokine production in Behcet's disease

Gunes Parlakgul, Ekin Guney, Burak Erer, Zeki Kılıcaslan, Haner Direskeneli, Ahmet Gul, Guher Saruhan-Direskeneli Arthritis Research & Therapy 2013, 15:R15 (21 January 2013)

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Editorial   Free

(Auto)immunity to cartilage matrix proteins - a time bomb?

Raimund W Kinne Arthritis Research & Therapy 2012, 15:101 (21 January 2013)

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Research article   Open Access

Scoring radiographic progression in ankylosing spondylitis: should we use the modified Stoke Ankylosing Spondylitis Spine Score (mSASSS) or the Radiographic Ankylosing Spondylitis Spinal Score (RASSS)?

Sofia Ramiro, Astrid van Tubergen, Carmen Stolwijk, Robert Landewé, Filip van de Bosch, Maxime Dougados, Désirée van der Heijde Arthritis Research & Therapy 2013, 15:R14 (17 January 2013)

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Research article   Open Access

Disease severity in K/BxN serum transfer-induced arthritis is not affected by IL-33 deficiency

Praxedis Martin, Dominique Talabot-Ayer, Christian Seemayer, Solenne Vigne, Céline Lamacchia, Emiliana Rodriguez, Axel Finckh, Dirk E Smith, Cem Gabay, Gaby Palmer Arthritis Research & Therapy 2013, 15:R13 (16 January 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

The spectrum of renal thrombotic microangiopathy in lupus nephritis

Di Song, Li-hua Wu, Feng-mei Wang, Xiao-wei Yang, Di Zhu, Min Chen, Feng Yu, Gang Liu, Ming-hui Zhao Arthritis Research & Therapy 2013, 15:R12 (15 January 2013)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Association of the AIRE gene with susceptibility to rheumatoid arthritis in a European population: a case control study

José-Raúl García-Lozano, Belén Torres-Agrela, Marco-Antonio Montes-Cano, Lourdes Ortiz-Fernández, Marta Conde-Jaldón, María Teruel, Alicia García, Antonio Núñez-Roldán, Javier Martín, María-Francisca González-Escribano Arthritis Research & Therapy 2013, 15:R11 (15 January 2013)

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Research article   Open Access

Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis

Keiko Aida-Yasuoka, Christine Peoples, Hidekata Yasuoka, Pamela Hershberger, Katelynn Thiel, Jane A Cauley, Thomas A Medsger, Carol A Feghali-Bostwick Arthritis Research & Therapy 2013, 15:R10 (10 January 2013)

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Research article   Open Access

Predictors of Chikungunya rheumatism: a prognostic survey ancillary to the TELECHIK cohort study

Patrick Gérardin, Adrian Fianu, Alain Michault, Corinne Mussard, Karim Boussaïd, Olivier Rollot, Philippe Grivard, Somar Kassab, Eric Bouquillard, Gianandrea Borgherini, Bernard-Alex Gaüzère, Denis Malvy, Gérard Bréart, François Favier Arthritis Research & Therapy 2013, 15:R9 (9 January 2013)

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Research article   Open Access

Prognostic impact of coronary microcirculation abnormalities in systemic sclerosis: a prospective study to evaluate the role of non-invasive tests

Alessandra Vacca, Roberta Montisci, Pietro Garau, Paolo Siotto, Matteo Piga, Alberto Cauli, Massimo Ruscazio, Luigi Meloni, Sabino Iliceto, Alessandro Mathieu Arthritis Research & Therapy 2013, 15:R8 (9 January 2013)

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Research article   Open Access

Atherosclerotic cardiovascular disease and dermatomyositis: an analysis of the Nationwide Inpatient Sample survey

Eleni Linos, David Fiorentino, Bharathi Lingala, Eswar Krishnan, Lorinda Chung Arthritis Research & Therapy 2013, 15:R7 (8 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Patients suffering from both dermatomyositis and an atherosclerotic cardiovascular disease (CVD) are twice as likely to die during inpatient stay compared to controls with CVD, and dermatomyositis patients without CVD.

Research article   Open Access

Patient-level pooled analysis of adjudicated gastrointestinal outcomes in celecoxib clinical trials: meta-analysis of 51,000 patients enrolled in 52 randomized trials

Andrew Moore, Geoffrey Makinson, Chunming Li Arthritis Research & Therapy 2013, 15:R6 (8 January 2013)

Abstract | Full text | PDF | PubMed | F1000 Biology

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MMP13 is a critical target gene during the progression of osteoarthritis

Meina Wang, Erik R Sampson, Hongting Jin, Jia Li, Qiao H Ke, Hee-Jeong Im, Di Chen Arthritis Research & Therapy 2013, 15:R5 (8 January 2013)

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Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis - a systematic review of the literature

David F Ten Cate, Jolanda J Luime, Nanno Swen, Andreas H Gerards, Mike H De Jager, Natalja M Basoski, Johanna MW Hazes, Cees J Haagsma, Johannes WG Jacobs Arthritis Research & Therapy 2013, 15:R4 (8 January 2013)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Ultrasonography has added value to clinical examination in diagnosing early rheumatoid arthritis and assessing remission, which could facilitate the provision of earlier and more effective treatments.

Research article   Open Access

OPN gene polymorphisms influence the risk of knee OA and OPN levels in synovial fluid in a Chinese population

Yongqing Jiang, Meng Yao, Qingpeng Liu, Changwei Zhou Arthritis Research & Therapy 2013, 15:R3 (5 January 2013)

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Research article   Open Access

Low-field magnetic resonance imaging study on carpal arthritis in systemic sclerosis - low-grade erosive arthritis of carpal bones is an unexpected and frequent disease manifestation

Elif Akbayrak, Robert Dinser, Ulf Müller-Ladner, Ingo H Tarner Arthritis Research & Therapy 2013, 15:R2 (4 January 2013)

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Research article   Open Access

Persistence of antibody response 1.5 years after vaccination using 7-valent pneumococcal conjugate vaccine in patients with arthritis treated with different antirheumatic drugs

Meliha Crnkic Kapetanovic, Tore Saxne, Lennart Truedsson, Pierre Geborek Arthritis Research & Therapy 2013, 15:R1 (4 January 2013)

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Lupus nephritis - alarmins may sound the alarm?

Tianfu Wu, Chandra Mohan Arthritis Research & Therapy 2012, 14:129 (31 December 2012)

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T cells in myositis

Vivianne Malmström, Paulius Venalis, Inka Albrecht Arthritis Research & Therapy 2012, 14:230 (28 December 2012)

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Research article   Open Access

KCNA5 gene is not confirmed as a systemic sclerosis-related pulmonary arterial hypertension genetic susceptibility factor

Lara Bossini-Castillo, Carmen P Simeon, Lorenzo Beretta, Jasper Broen, Madelon C Vonk, José Callejas, Patricia Carreira, Luis Rodríguez-Rodríguez, Rosa García-Portales, Miguel A González-Gay, Ivan Castellví, María Camps, Carlos Tolosa, Esther Vicente-Rabaneda, María Egurbide, the Spanish Scleroderma Group, Annemie J Schuerwegh, Roger Hesselstrand, Claudio Lunardi, Jacob M van Laar, Paul Shiels, Ariane Herrick, Jane Worthington, Christopher Denton, Timothy RDJ Radstake, Carmen Fonseca, Javier Martin Arthritis Research & Therapy 2012, 14:R273 (27 December 2012)

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Inflammatory lesions in the bone marrow of rheumatoid arthritis patients: a morphological perspective

Serena Bugatti, Antonio Manzo, Roberto Caporali, Carlomaurizio Montecucco Arthritis Research & Therapy 2012, 14:229 (27 December 2012)

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Imaging joints for calcium pyrophosphate crystal deposition: a knock to the knees

Robert Terkeltaub Arthritis Research & Therapy 2012, 14:128 (27 December 2012)

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Research article   Open Access

Ghrelin and adipokines as circulating markers of disease activity in patients with Takayasu arteritis

Hatice Yilmaz, Vedat Gerdan, Didem Kozaci, Dilek Solmaz, Servet Akar, Gercek Can, Aytac Gulcu, Yigit Goktay, Ismail Sari, Merih Birlik, Nurullah Akkoc, Fatos Onen Arthritis Research & Therapy 2012, 14:R272 (21 December 2012)

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Editorial   Free

Can measuring urinary biomarkers improve the management of lupus nephritis?

Anisur Rahman Arthritis Research & Therapy 2012, 14:127 (19 December 2012)

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Rheumatology meets radiology in the hot soup of Gutta

Tim L Jansen Arthritis Research & Therapy 2012, 14:126 (19 December 2012)

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