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Direct transplantation of mesenchymal stem cells into the knee joints of Hartley strain guinea pigs with spontaneous osteoarthritis
Mitsuhiko Sato, Kenzo Uchida, Hideaki Nakajima, Tsuyoshi Miyazaki, Alexander Guerrero, Shuji Watanabe, Sally Roberts, Hisatoshi Baba Arthritis Research & Therapy 2012, 14:R31 (7 February 2012)
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Baseline serum MMP-3 levels in patients with Rheumatoid Arthritis are still independently predictive of radiographic progression in a longitudinal observational cohort at 8 years follow up
Mark Houseman, Catherine Potter, Nicola Marshall, Rachel Lakey, Tim Cawston, Ian Griffiths, Steven Young-Min, John D Isaacs Arthritis Research & Therapy 2012, 14:R30 (7 February 2012)
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The neuropeptide neuromedin U promotes autoantibody-mediated arthritis
Sindhuja M Rao, Jennifer L Auger, Philippe Gaillard, Ralph Weissleder, Etsuko Wada, Richard Torres, Masayasu Kojima, Christophe Benoist, Diane Mathis, Bryce A Binstadt Arthritis Research & Therapy 2012, 14:R29 (7 February 2012)
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Editor’s summary
Neuromedin U (NMU), a neuropeptide produced by bone-marrow-derived cells, promotes autoantibody-mediated arthritis in mice, suggesting NMU may be a potential therapeutic target in inflammatory arthritis.
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Low copy number of the FCGR3B gene and rheumatoid arthritis: a case-control study and meta-analysis
Scott W Graf, Sue Lester, Johannes C Nossent, Catherine L Hill, Susanna M Proudman, Anita Lee, Maureen Rischmueller Arthritis Research & Therapy 2012, 14:R28 (7 February 2012)
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Takayasu's arteritis is associated with HLA-B*52, but not with HLA-B*51, in Turkey
Ziver Sahin, Muge Bıcakcıgil, Kenan Aksu, Sevil Kamali, Servet Akar, Fatos Onen, Omer Karadag, Zeynep Ozbalkan, Askin Ates, Huseyin TE Ozer, Vuslat Yilmaz, Emire Seyahi, Mehmet A Ozturk, Ayse Cefle, Veli Cobankara, A Mesut Onat, Ercan Tunc, Nursen Düzgün, Sibel Z Aydin, Neslihan Yilmaz, İzzet Fresko, Yasar Karaaslan, Sedat Kiraz, Nurullah Akkoc, Murat Inanc, Gokhan Keser, F Aytul Uyar, Haner Direskeneli, Güher Saruhan-Direskeneli, the Turkish Takayasu Study Group et al.
Arthritis Research & Therapy 2012, 14:R27 (6 February 2012)
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Pre-disease pregnancy complications and systemic sclerosis: pathogenic or pre-clinical?
Eliza Chakravarty Arthritis Research & Therapy 2012, 14:102 (6 February 2012)
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An in vivo investigation of the initiation and progression of subchondral cysts in a rodent model of secondary osteoarthritis
David D McErlain, Veronica Ulici, Mark Darling, Joseph S Gati, Vasek Pitelka, Frank Beier, David W Holdsworth Arthritis Research & Therapy 2012, 14:R26 (3 February 2012)
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Specific post-translational histone modifications of neutrophil extracellular traps as immunogens and potential targets of lupus autoantibodies
Chih Liu, Stephanie Tangsombatvisit, Jacob M Rosenberg, Gil Mandelbaum, Emily C Gillespie, Or P Gozani, Ash A Alizadeh, Paul J Utz Arthritis Research & Therapy 2012, 14:R25 (2 February 2012)
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A profile of immune response to herpesvirus is associated with radiographic joint damage in rheumatoid arthritis
John M Davis, Keith L Knutson, John A Skinner, Michael A Strausbauch, Cynthia S Crowson, Terry M Therneau, Peter J Wettstein, Eric L Matteson, Sherine E Gabriel Arthritis Research & Therapy 2012, 14:R24 (31 January 2012)
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Therapy of lupus nephritis: lessons learned from clinical research and daily care of patients
Frédéric A Houssiau Arthritis Research & Therapy 2012, 14:202 (31 January 2012)
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Extracellular nicotinamide phosphoribosyltransferase (NAMPT/visfatin) inhibits insulin-like growth factor-1 signaling and proteoglycan synthesis in human articular chondrocytes
Raghunatha R Yammani, Richard F Loeser Arthritis Research & Therapy 2012, 14:R23 (30 January 2012)
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Is there any scientific evidence for the use of glucosamine in the management of human osteoarthritis?
Yves Henrotin, Ali Mobasheri, Marc Marty Arthritis Research & Therapy 2012, 14:201 (30 January 2012)
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Predictors of survival in a cohort of patients with polymyositis and dermatomyositis: effect of corticosteroids, methotrexate and azathioprine
Elena Schiopu, Kristine Phillips, Paul M MacDonald, Leslie J Crofford, Emily C Somers Arthritis Research & Therapy 2012, 14:R22 (27 January 2012)
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A randomised controlled trial of a self-management education program for osteoarthritis of the knee delivered by health care professionals
Sophie Coleman, N Kathryn Briffa, Graeme Carroll, Charles Inderjeeth, Nicola Cook, Jean McQuade Arthritis Research & Therapy 2012, 14:R21 (27 January 2012)
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Local administration of glucocorticoids decreases synovial citrullination in rheumatoid arthritis
Dimitrios Makrygiannakis, Shankar Revu, Marianne Engström, Erik af Klint, Anthony P Nicholas, Ger JM Pruijn, Anca I Catrina Arthritis Research & Therapy 2012, 14:R20 (27 January 2012)
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Editor’s summary
Glucocorticoid reduced levels of protein citrullination and the enzyme peptidylargininedeiminase 4 (PAD4) in the joints of patients with rheumatoid arthritis, and this was matched by a decrease in visible signs of inflammation.
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Restrictive pulmonary function is more prevalent in patients with ankylosing spondylitis than in matched population controls and is associated with impaired spinal mobility: a comparative study
Gunnhild Berdal, Silje Halvorsen, Désirée van der Heijde, Morten Mowe, Hanne Dagfinrud Arthritis Research & Therapy 2012, 14:R19 (25 January 2012)
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Reduced spinal mobility is associated with restrictive pulmonary function in patients with ankylosing spondylitis, emphasizing the importance of maintaining spinal flexibility in the management of the disease.
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Neutralization of IL-17 ameliorates uveitis but damages photoreceptors in a murine model of spondyloarthritis
Jelena M Kezic, Tibor T Glant, James T Rosenbaum, Holly L Rosenzweig Arthritis Research & Therapy 2012, 14:R18 (23 January 2012)
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Effect of in utero exposure to diethylstilbestrol on lumbar and femoral bone, articular cartilage, and the intervertebral disc in male and female adult mice progeny with and without swimming exercise
Sora Rowas, Rami Haddad, Rahul Gawri, Abdul Al Ma'awi, Lorraine E Chalifour, John Antoniou, Fackson Mwale Arthritis Research & Therapy 2012, 14:R17 (23 January 2012)
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Autoimmunity induced by human cytomegalovirus in patients with systemic lupus erythematosus
Cecilia Söderberg-Nauclér Arthritis Research & Therapy 2012, 14:101 (23 January 2012)
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Tight regulation of wingless-type signaling in the articular cartilage - subchondral bone biomechanical unit: transcriptomics in Frzb-knockout mice
Liesbet Lodewyckx, Frédéric Cailotto, Sarah Thysen, Frank P Luyten, Rik J Lories Arthritis Research & Therapy 2012, 14:R16 (20 January 2012)
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Serum COMP-C3b complexes in rheumatic diseases and relation to anti-TNF-α treatment
Kaisa E Happonen, Tore Saxne, Pierre Geborek, Maria Andersson, Anders A Bengtsson, Roger Hesselstrand, Dick Heinegård, Anna M Blom Arthritis Research & Therapy 2012, 14:R15 (20 January 2012)
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Interleukin-34 produced by human fibroblast-like synovial cells in rheumatoid arthritis supports osteoclastogenesis
Seung-Jun Hwang, Bongkun Choi, Soon-Suk Kang, Jae-Ho Chang, Yong-Gil Kim, Yeon-Ho Chung, Dong Sohn, Min So, Chang-Keun Lee, William H Robinson, Eun-Ju Chang Arthritis Research & Therapy 2012, 14:R14 (20 January 2012)
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A longitudinal study of the association between dietary factors, serum lipids, and bone marrow lesions of the knee
Dawn Doré, Jonathon de Hoog, Graham Giles, Changhai Ding, Flavia Cicuttini, Graeme Jones Arthritis Research & Therapy 2012, 14:R13 (18 January 2012)
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The distribution pattern of critically short telomeres in human osteoarthritic knees
Maria Harbo, Laila Bendix, Anne-Christine Bay-Jensen, Jesper Graakjaer, Kent Søe, Thomas L Andersen, Per Kjaersgaard-Andersen, Steen Koelvraa, Jean-Marie Delaisse Arthritis Research & Therapy 2012, 14:R12 (18 January 2012)
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An increase in the number of cells with ultra short telomeres is associated with increased severity of osteoarthritis, proximity to the most damaged section of the joint, and with senescence.
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Maraviroc, a chemokine receptor-5 antagonist, fails to demonstrate efficacy in the treatment of patients with rheumatoid arthritis in a randomized, double-blind placebo-controlled trial
Dona L Fleishaker, Juan A Garcia Meijide, Andriy Petrov, Michael Kohen, Xin Wang, Sujatha Menon, Thomas C Stock, Charles A Mebus, James M Goodrich, Howard B Mayer, Bernhardt G Zeiher Arthritis Research & Therapy 2012, 14:R11 (17 January 2012)
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