Arthritis Research & Therapy

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		Research article Is IL-6 an appropriate target to treat spondyloarthritis patients refractory to anti-TNF therapy? a multicentre retrospective observational study Fernando Lekpa, Cécile Poulain, Daniel Wendling, Martin Soubrier, Michel De Bandt, Jean Berthelot, Philippe Gaudin, Eric Toussirot, Philippe Goupille, Thao Pham, Jérémie Sellam, Rémy Bruckert, Muriel Paul, Valérie Farrenq, Pascal Claudepierre, the Club Rhumatismes et Inflammation Arthritis Research & Therapy 2012, 14:R53 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Moving instead of asking? Performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis Salima FE van Weely, J Christiaan van Denderen, Martijn PM Steultjens, Marike van der Leeden, Michael T Nurmohamed, Joost Dekker, Ben AC Dijkmans, Irene E van der Horst-Bruinsma Arthritis Research & Therapy 2012, 14:R52 (8 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration Takashi Yurube, Toru Takada, Teppei Suzuki, Kenichiro Kakutani, Koichiro Maeno, Minoru Doita, Masahiro Kurosaka, Kotaro Nishida Arthritis Research & Therapy 2012, 14:R51 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis Marie Hudson, Janet Pope, Michael Mahler, Solène Tatibouet, Russell Steele, Murray Baron, Canadian Scleroderma Research Group (CSRG), Marvin J Fritzler Arthritis Research & Therapy 2012, 14:R50 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage Girish Ramaswamy, Philip Sohn, Alan Eberhardt, Rosa Serra Arthritis Research & Therapy 2012, 14:R49 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity Fumihito Suzuki, Tetsuo Kubota, Yasunari Miyazaki, Kinya Ishikawa, Masashi Ebisawa, Shunsei Hirohata, Takashi Ogura, Hidehiro Mizusawa, Toshio Imai, Nobuyuki Miyasaka, Toshihiro Nanki Arthritis Research & Therapy 2012, 14:R48 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Dutch translation and cross-cultural adaptation of the PROMIS^®physical function item bank and cognitive pre-test in Dutch arthritis patients Martijn AH Oude Voshaar, Peter M ten Klooster, Erik Taal, Eswar Krishnan, Mart AFJ van de Laar Arthritis Research & Therapy 2012, 14:R47 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The Patient-Reported Outcomes Measurement Information System (PROMIS) physical function item bank translated into Dutch is semantically and conceptually equivalent to the original, with all items comprehended by patients as intended.
		Research article Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study Johanna T Gustafsson, Julia F Simard, Iva Gunnarsson, Kerstin Elvin, Ingrid E Lundberg, Lars-Olof Hansson, Anders Larsson, Elisabet Svenungsson Arthritis Research & Therapy 2012, 14:R46 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes Chiyoko Sekine, Akemi Koyanagi, Noriko Koyama, Katsuto Hozumi, Shigeru Chiba, Hideo Yagita Arthritis Research & Therapy 2012, 14:R45 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study Evangelia Zampeli, Athanase Protogerou, Kimon Stamatelopoulos, Kalliopi Fragiadaki, Christina G Katsiari, Katerina Kyrkou, Christos M Papamichael, Myron Mavrikakis, Peter Nightingale, George D Kitas, Petros P Sfikakis Arthritis Research & Therapy 2012, 14:R44 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis Altan Ercan, Jing Cui, Melissa M Hazen, Franak Batliwalla, Louise Royle, Pauline M Rudd, Jonathan S Coblyn, Nancy Shadick, Michael E Weinblatt, Peter Gregersen, David M Lee, Peter A Nigrovic Arthritis Research & Therapy 2012, 14:R43 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Plasma proteins take their toll on the joint in osteoarthritis Steven R Goldring, Carla R Scanzello Arthritis Research & Therapy 2012, 14:111 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis Raquel López-Mejías, Carlos González-Juanatey, Mercedes García-Bermúdez, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Javier Llorca, Javier Martín, Miguel A González-Gay Arthritis Research & Therapy 2012, 14:R42 (1 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Taking responsibility for the early assessment and treatment of patients with musculoskeletal pain: a review and critical analysis Nadine E Foster, Jan Hartvigsen, Peter R Croft Arthritis Research & Therapy 2012, 14:205 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Clinical examination or whole-body magnetic resonance imaging: the Holy Grail of spondyloarthritis imaging Winston J Rennie Arthritis Research & Therapy 2012, 14:110 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Role of environmental factors in autoantibody production - importance of a detailed analysis in a small cohort Minoru Satoh, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:109 (29 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Inhibiting citrullination in rheumatoid arthritis: taking fuel from the fire Benjamin AC Fisher, Patrick J Venables Arthritis Research & Therapy 2012, 14:108 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study Berit M Sverdrup, Henrik Källberg, Lars Klareskog, Lars Alfredsson, Epidemiological Investigation of Rheumatoid Arthritis Study Group Arthritis Research & Therapy 2012, 14:R41 (28 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndrome Hongen Yin, Cuong Q Nguyen, Yuval Samuni, Toshimitsu Uede, Ammon B Peck, John A Chiorini Arthritis Research & Therapy 2012, 14:R40 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study Jon T Giles, Justyna Fert-Bober, Jin Park, Clifton O Bingham, Felipe Andrade, Karen Fox-Talbot, Dimitrios Pappas, Antony Rosen, Jennifer van Eyk, Joan M Bathon, Marc K Halushka Arthritis Research & Therapy 2012, 14:R39 (24 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial The BRIC-GARN Meeting 2011: of mice and men David S Pisetsky Arthritis Research & Therapy 2012, 14:107 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial How does BAFF activate B cells in patients with autoimmune diseases? Xavier Mariette Arthritis Research & Therapy 2012, 14:106 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-Terminal kinase pathway Sang-il Lee, David L Boyle, Andres Berdeja, Gary S Firestein Arthritis Research & Therapy 2012, 14:R38 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Abatacept versus other biologics in methotrexate inadequate responders with rheumatoid arthritis: you like tomato and I like tomahto... let's call the whole thing off Yusuf Yazici Arthritis Research & Therapy 2012, 14:104 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Review Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus Erik A Korte, Patrick M Gaffney, David W Powell Arthritis Research & Therapy 2012, 14:204 (20 February 2012) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Is IL-6 an appropriate target to treat spondyloarthritis patients refractory to anti-TNF therapy? a multicentre retrospective observational study Fernando Lekpa, Cécile Poulain, Daniel Wendling, Martin Soubrier, Michel De Bandt, Jean Berthelot, Philippe Gaudin, Eric Toussirot, Philippe Goupille, Thao Pham, Jérémie Sellam, Rémy Bruckert, Muriel Paul, Valérie Farrenq, Pascal Claudepierre, the Club Rhumatismes et Inflammation Arthritis Research & Therapy 2012, 14:R53 (9 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Moving instead of asking? Performance-based tests and BASFI-questionnaire measure different aspects of physical function in ankylosing spondylitis Salima FE van Weely, J Christiaan van Denderen, Martijn PM Steultjens, Marike van der Leeden, Michael T Nurmohamed, Joost Dekker, Ben AC Dijkmans, Irene E van der Horst-Bruinsma Arthritis Research & Therapy 2012, 14:R52 (8 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Rat tail static compression model mimics extracellular matrix metabolic imbalances of matrix metalloproteinases, aggrecanases, and tissue inhibitors of metalloproteinases in intervertebral disc degeneration Takashi Yurube, Toru Takada, Teppei Suzuki, Kenichiro Kakutani, Koichiro Maeno, Minoru Doita, Masahiro Kurosaka, Kotaro Nishida Arthritis Research & Therapy 2012, 14:R51 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Clinical significance of antibodies to Ro52/TRIM21 in systemic sclerosis Marie Hudson, Janet Pope, Michael Mahler, Solène Tatibouet, Russell Steele, Murray Baron, Canadian Scleroderma Research Group (CSRG), Marvin J Fritzler Arthritis Research & Therapy 2012, 14:R50 (6 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Altered responsiveness to TGF-β results in reduced Papss2 expression and alterations in the biomechanical properties of mouse articular cartilage Girish Ramaswamy, Philip Sohn, Alan Eberhardt, Rosa Serra Arthritis Research & Therapy 2012, 14:R49 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity Fumihito Suzuki, Tetsuo Kubota, Yasunari Miyazaki, Kinya Ishikawa, Masashi Ebisawa, Shunsei Hirohata, Takashi Ogura, Hidehiro Mizusawa, Toshio Imai, Nobuyuki Miyasaka, Toshihiro Nanki Arthritis Research & Therapy 2012, 14:R48 (6 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Dutch translation and cross-cultural adaptation of the PROMIS^®physical function item bank and cognitive pre-test in Dutch arthritis patients Martijn AH Oude Voshaar, Peter M ten Klooster, Erik Taal, Eswar Krishnan, Mart AFJ van de Laar Arthritis Research & Therapy 2012, 14:R47 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The Patient-Reported Outcomes Measurement Information System (PROMIS) physical function item bank translated into Dutch is semantically and conceptually equivalent to the original, with all items comprehended by patients as intended.
		Research article Risk factors for cardiovascular mortality in patients with systemic lupus erythematosus, a prospective cohort study Johanna T Gustafsson, Julia F Simard, Iva Gunnarsson, Kerstin Elvin, Ingrid E Lundberg, Lars-Olof Hansson, Anders Larsson, Elisabet Svenungsson Arthritis Research & Therapy 2012, 14:R46 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes Chiyoko Sekine, Akemi Koyanagi, Noriko Koyama, Katsuto Hozumi, Shigeru Chiba, Hideo Yagita Arthritis Research & Therapy 2012, 14:R45 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Predictors of new atherosclerotic carotid plaque development in patients with rheumatoid arthritis: a longitudinal study Evangelia Zampeli, Athanase Protogerou, Kimon Stamatelopoulos, Kalliopi Fragiadaki, Christina G Katsiari, Katerina Kyrkou, Christos M Papamichael, Myron Mavrikakis, Peter Nightingale, George D Kitas, Petros P Sfikakis Arthritis Research & Therapy 2012, 14:R44 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Hypogalactosylation of serum N-glycans fails to predict clinical response to methotrexate and TNF inhibition in rheumatoid arthritis Altan Ercan, Jing Cui, Melissa M Hazen, Franak Batliwalla, Louise Royle, Pauline M Rudd, Jonathan S Coblyn, Nancy Shadick, Michael E Weinblatt, Peter Gregersen, David M Lee, Peter A Nigrovic Arthritis Research & Therapy 2012, 14:R43 (5 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Plasma proteins take their toll on the joint in osteoarthritis Steven R Goldring, Carla R Scanzello Arthritis Research & Therapy 2012, 14:111 (5 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article The lp13.3 genomic region -rs599839- is associated with endothelial dysfunction in patients with rheumatoid arthritis Raquel López-Mejías, Carlos González-Juanatey, Mercedes García-Bermúdez, Santos Castañeda, José A Miranda-Filloy, Ricardo Blanco, Javier Llorca, Javier Martín, Miguel A González-Gay Arthritis Research & Therapy 2012, 14:R42 (1 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Taking responsibility for the early assessment and treatment of patients with musculoskeletal pain: a review and critical analysis Nadine E Foster, Jan Hartvigsen, Peter R Croft Arthritis Research & Therapy 2012, 14:205 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Clinical examination or whole-body magnetic resonance imaging: the Holy Grail of spondyloarthritis imaging Winston J Rennie Arthritis Research & Therapy 2012, 14:110 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Role of environmental factors in autoantibody production - importance of a detailed analysis in a small cohort Minoru Satoh, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:109 (29 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial Inhibiting citrullination in rheumatoid arthritis: taking fuel from the fire Benjamin AC Fisher, Patrick J Venables Arthritis Research & Therapy 2012, 14:108 (29 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Usage of skin care products and risk of rheumatoid arthritis: results from the Swedish EIRA study Berit M Sverdrup, Henrik Källberg, Lars Klareskog, Lars Alfredsson, Epidemiological Investigation of Rheumatoid Arthritis Study Group Arthritis Research & Therapy 2012, 14:R41 (28 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Local delivery of AAV2-CTLA4IgG decreases sialadenitis and improves gland function in the C57BL/6.NOD-Aec1Aec2 mouse model of Sjögren's syndrome Hongen Yin, Cuong Q Nguyen, Yuval Samuni, Toshimitsu Uede, Ammon B Peck, John A Chiorini Arthritis Research & Therapy 2012, 14:R40 (27 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Myocardial citrullination in rheumatoid arthritis: a correlative histopathologic study Jon T Giles, Justyna Fert-Bober, Jin Park, Clifton O Bingham, Felipe Andrade, Karen Fox-Talbot, Dimitrios Pappas, Antony Rosen, Jennifer van Eyk, Joan M Bathon, Marc K Halushka Arthritis Research & Therapy 2012, 14:R39 (24 February 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Editorial The BRIC-GARN Meeting 2011: of mice and men David S Pisetsky Arthritis Research & Therapy 2012, 14:107 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial How does BAFF activate B cells in patients with autoimmune diseases? Xavier Mariette Arthritis Research & Therapy 2012, 14:106 (24 February 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Regulation of inflammatory arthritis by the upstream kinase mitogen activated protein kinase kinase 7 in the c-Jun N-Terminal kinase pathway Sang-il Lee, David L Boyle, Andres Berdeja, Gary S Firestein Arthritis Research & Therapy 2012, 14:R38 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Abatacept versus other biologics in methotrexate inadequate responders with rheumatoid arthritis: you like tomato and I like tomahto... let's call the whole thing off Yusuf Yazici Arthritis Research & Therapy 2012, 14:104 (21 February 2012) Abstract \| Full text \| PDF \| PubMed
		Review Contributions of mass spectrometry-based proteomics to defining cellular mechanisms and diagnostic markers for systemic lupus erythematosus Erik A Korte, Patrick M Gaffney, David W Powell Arthritis Research & Therapy 2012, 14:204 (20 February 2012) Abstract \| Full text \| PDF \| PubMed