Arthritis Research & Therapy

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		Research article Risk of end-stage renal disease associated with gout: a nationwide population study Kuang-Hui Yu, Chang-Fu Kuo, Shue-Fen Luo, Lai-Chu See, I-Jun Chou, Hsiao-Chun Chang, Meng-Jiun Chiou Arthritis Research & Therapy 2012, 14:R83 (18 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes Ioanna Papathanasiou, Konstantinos N Malizos, Aspasia Tsezou Arthritis Research & Therapy 2012, 14:R82 (18 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study Ying Chen, Peter T Dawes, Jon C Packham, Derek L Mattey Arthritis Research & Therapy 2012, 14:R81 (18 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus Shui-Lian Yu, Paul KS Chan, Chun-Kwok Wong, Cheuk-Chun Szeto, Suzanne C Ho, Karine So, May MY Yu, So-Fan Yim, Tak-Hong Cheung, Martin CS Wong, Jo LK Cheung, Apple CM Yeung, Edmund K Li, Lai-Shan Tam Arthritis Research & Therapy 2012, 14:R80 (18 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Autoantibodies to transcription intermediary factor (TIF)1β associated with dermatomyositis Minoru Satoh, Jason YF Chan, Steven J Ross, Yi Li, Yoshioki Yamasaki, Hidehiro Yamada, Monica Vazquez-del Mercado, Marcelo H Petri, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Reyes, Eric S Sobel, Westley H Reeves, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:R79 (18 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis Kyle D Allen, Brian A Mata, Mostafa A Gabr, Janet L Huebner, Samuel B Adams, Virginia B Kraus, Daniel O Schmitt, Lori A Setton Arthritis Research & Therapy 2012, 14:R78 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Circulating and synovial antibody profiling of juvenile arthritis patients by nucleic acid programmable protein arrays David S Gibson, Ji Qiu, Eliseo A Mendoza, Kristi Barker, Madeleine E Rooney, Joshua LaBaer Arthritis Research & Therapy 2012, 14:R77 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Estradiol ameliorates arthritis and protects against systemic bone loss in Staphylococcus aureus infection in mice Inger Gjertsson, Marie K Lagerquist, Erik Kristiansson, Hans Carlsten, Catharina Lindholm Arthritis Research & Therapy 2012, 14:R76 (16 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4 Jing Li, Jingang Huang, Liming Dai, Degang Yu, Qian Chen, Xiaoling Zhang, Kerong Dai Arthritis Research & Therapy 2012, 14:R75 (16 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The microRNA miR-146a may reduce cellular response to transforming growth factor-beta through targeted inhibition of Smad4 in cartilage, thus increasing vascular endothelial growth factor levels, and increasing chondrocyte apoptosis.
		Research article Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis Carmen A Ambarus, Troy Noordenbos, Maria JH de Hair, Paul P Tak, Dominique LP Baeten Arthritis Research & Therapy 2012, 14:R74 (11 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Increased frequency of CCR4+ and CCR6+ memory T-cells including CCR7+CD45RA^medvery early memory cells in granulomatosis with polyangiitis (Wegener's) Ursula Fagin, Silke Pitann, Wolfgang L Gross, Peter Lamprecht Arthritis Research & Therapy 2012, 14:R73 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Induction of superficial zone protein (SZP)/lubricin/PRG 4 in muscle-derived mesenchymal stem/progenitor cells by transforming growth factor-β1 and bone morphogenetic protein-7 José A Andrades, Shirley C Motaung, Pedro Jiménez-Palomo, Silvia Claros, José M López-Puerta, José Becerra, Thomas M Schmid, A Hari Reddi Arthritis Research & Therapy 2012, 14:R72 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Correction Correction: FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development Rizwanul Haque, Fengyang Lei, Xiaofang Xiong, Yuzhang Wu, Jianxun Song Arthritis Research & Therapy 2012, 14:401 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Knotting the NETs: Analyzing histone modifications in neutrophil extracellular traps Indira Neeli, Marko Radic Arthritis Research & Therapy 2012, 14:115 (6 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Bone formation rather than inflammation reflects Ankylosing Spondylitis activity on PET-CT: a pilot study Stefan TG Bruijnen, Mignon AC van der Weijden, Joannes P Klein, Otto S Hoekstra, Ronald Boellaard, J Christiaan van Denderen, Ben AC Dijkmans, Alexandre E Voskuyl, Irene E van der Horst-Bruinsma, Conny J van der Laken Arthritis Research & Therapy 2012, 14:R71 (2 April 2012) Abstract \| Full text \| PDF \| PubMed
		Review Placebo analgesia: cognitive influences on therapeutic outcome Alison Watson, Andrea Power, Christopher Brown, Wael El-Deredy, Anthony Jones Arthritis Research & Therapy 2012, 14:206 (30 March 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial What is the future of CCR5 antagonists in rheumatoid arthritis? Tsutomu Takeuchi, Hideto Kameda Arthritis Research & Therapy 2012, 14:114 (30 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Replication study confirms the association between UBAC2 and Behçet's disease in two independent Chinese sets of patients and controls Shengping Hou, Qinmeng Shu, Zhengxuan Jiang, Yuanyuan Chen, Fuzhen Li, Feilan Chen, Aize Kijlstra, Peizeng Yang Arthritis Research & Therapy 2012, 14:R70 (29 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes Sarah-Salwa Nebbaki, Fatima El Mansouri, Hassan Afif, Mohit Kapoor, Mohamed Benderdour, Nicolas Duval, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Hassan Fahmi Arthritis Research & Therapy 2012, 14:R69 (28 March 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Meryl Streep and the problems of clinical trials David A Isenberg Arthritis Research & Therapy 2012, 14:113 (23 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Sustained rheumatoid arthritis remission is uncommon in clinical practice Femke HM Prince, Vivian P Bykerk, Nancy A Shadick, Bing Lu, Jing Cui, Michelle Frits, Christine K Iannaccone, Michael E Weinblatt, Daniel H Solomon Arthritis Research & Therapy 2012, 14:R68 (19 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In clinical practice only a minority of patients with rheumatoid arthritis (RA) are in sustained remission, suggesting strict monitoring is required even once remission is reached.
		Research article Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: a cross-sectional study Ahmed Solomon, Gavin R Norton, Angela J Woodiwiss, Patrick H Dessein Arthritis Research & Therapy 2012, 14:R67 (19 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Effect of pregnancy on serum cytokines in SLE patients Andrea Doria, Maurizio Cutolo, Anna Ghirardello, Margherita Zen, Danilo Villalta, Angela Tincani, Leonardo Punzi, Luca Iaccarino, Michelle Petri Arthritis Research & Therapy 2012, 14:R66 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Functional role of IL-22 in psoriatic arthritis Anupam Mitra, Smriti K Raychaudhuri, Siba P Raychaudhuri Arthritis Research & Therapy 2012, 14:R65 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial HMGB1: a smoking gun in lupus nephritis? David S Pisetsky Arthritis Research & Therapy 2012, 14:112 (14 March 2012) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Risk of end-stage renal disease associated with gout: a nationwide population study Kuang-Hui Yu, Chang-Fu Kuo, Shue-Fen Luo, Lai-Chu See, I-Jun Chou, Hsiao-Chun Chang, Meng-Jiun Chiou Arthritis Research & Therapy 2012, 14:R83 (18 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes Ioanna Papathanasiou, Konstantinos N Malizos, Aspasia Tsezou Arthritis Research & Therapy 2012, 14:R82 (18 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Interaction between smoking and functional polymorphism in the TGFB1 gene is associated with ischaemic heart disease and myocardial infarction in patients with rheumatoid arthritis: a cross-sectional study Ying Chen, Peter T Dawes, Jon C Packham, Derek L Mattey Arthritis Research & Therapy 2012, 14:R81 (18 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Antagonist-mediated down-regulation of toll-like receptors increases the prevalence of human papillomavirus infection in systemic lupus erythematosus Shui-Lian Yu, Paul KS Chan, Chun-Kwok Wong, Cheuk-Chun Szeto, Suzanne C Ho, Karine So, May MY Yu, So-Fan Yim, Tak-Hong Cheung, Martin CS Wong, Jo LK Cheung, Apple CM Yeung, Edmund K Li, Lai-Shan Tam Arthritis Research & Therapy 2012, 14:R80 (18 April 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Autoantibodies to transcription intermediary factor (TIF)1β associated with dermatomyositis Minoru Satoh, Jason YF Chan, Steven J Ross, Yi Li, Yoshioki Yamasaki, Hidehiro Yamada, Monica Vazquez-del Mercado, Marcelo H Petri, Luis J Jara, Miguel A Saavedra, Claudia Cruz-Reyes, Eric S Sobel, Westley H Reeves, Angela Ceribelli, Edward KL Chan Arthritis Research & Therapy 2012, 14:R79 (18 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Kinematic and dynamic gait compensations resulting from knee instability in a rat model of osteoarthritis Kyle D Allen, Brian A Mata, Mostafa A Gabr, Janet L Huebner, Samuel B Adams, Virginia B Kraus, Daniel O Schmitt, Lori A Setton Arthritis Research & Therapy 2012, 14:R78 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Circulating and synovial antibody profiling of juvenile arthritis patients by nucleic acid programmable protein arrays David S Gibson, Ji Qiu, Eliseo A Mendoza, Kristi Barker, Madeleine E Rooney, Joshua LaBaer Arthritis Research & Therapy 2012, 14:R77 (17 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Estradiol ameliorates arthritis and protects against systemic bone loss in Staphylococcus aureus infection in mice Inger Gjertsson, Marie K Lagerquist, Erik Kristiansson, Hans Carlsten, Catharina Lindholm Arthritis Research & Therapy 2012, 14:R76 (16 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article miR-146a, an IL-1β responsive miRNA, induces vascular endothelial growth factor and chondrocyte apoptosis by targeting Smad4 Jing Li, Jingang Huang, Liming Dai, Degang Yu, Qian Chen, Xiaoling Zhang, Kerong Dai Arthritis Research & Therapy 2012, 14:R75 (16 April 2012) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary The microRNA miR-146a may reduce cellular response to transforming growth factor-beta through targeted inhibition of Smad4 in cartilage, thus increasing vascular endothelial growth factor levels, and increasing chondrocyte apoptosis.
		Research article Intimal lining layer macrophages but not synovial sublining macrophages display an IL-10 polarized-like phenotype in chronic synovitis Carmen A Ambarus, Troy Noordenbos, Maria JH de Hair, Paul P Tak, Dominique LP Baeten Arthritis Research & Therapy 2012, 14:R74 (11 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Increased frequency of CCR4+ and CCR6+ memory T-cells including CCR7+CD45RA^medvery early memory cells in granulomatosis with polyangiitis (Wegener's) Ursula Fagin, Silke Pitann, Wolfgang L Gross, Peter Lamprecht Arthritis Research & Therapy 2012, 14:R73 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Induction of superficial zone protein (SZP)/lubricin/PRG 4 in muscle-derived mesenchymal stem/progenitor cells by transforming growth factor-β1 and bone morphogenetic protein-7 José A Andrades, Shirley C Motaung, Pedro Jiménez-Palomo, Silvia Claros, José M López-Puerta, José Becerra, Thomas M Schmid, A Hari Reddi Arthritis Research & Therapy 2012, 14:R72 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Correction Correction: FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development Rizwanul Haque, Fengyang Lei, Xiaofang Xiong, Yuzhang Wu, Jianxun Song Arthritis Research & Therapy 2012, 14:401 (10 April 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Knotting the NETs: Analyzing histone modifications in neutrophil extracellular traps Indira Neeli, Marko Radic Arthritis Research & Therapy 2012, 14:115 (6 April 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Bone formation rather than inflammation reflects Ankylosing Spondylitis activity on PET-CT: a pilot study Stefan TG Bruijnen, Mignon AC van der Weijden, Joannes P Klein, Otto S Hoekstra, Ronald Boellaard, J Christiaan van Denderen, Ben AC Dijkmans, Alexandre E Voskuyl, Irene E van der Horst-Bruinsma, Conny J van der Laken Arthritis Research & Therapy 2012, 14:R71 (2 April 2012) Abstract \| Full text \| PDF \| PubMed
		Review Placebo analgesia: cognitive influences on therapeutic outcome Alison Watson, Andrea Power, Christopher Brown, Wael El-Deredy, Anthony Jones Arthritis Research & Therapy 2012, 14:206 (30 March 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial What is the future of CCR5 antagonists in rheumatoid arthritis? Tsutomu Takeuchi, Hideto Kameda Arthritis Research & Therapy 2012, 14:114 (30 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Replication study confirms the association between UBAC2 and Behçet's disease in two independent Chinese sets of patients and controls Shengping Hou, Qinmeng Shu, Zhengxuan Jiang, Yuanyuan Chen, Fuzhen Li, Feilan Chen, Aize Kijlstra, Peizeng Yang Arthritis Research & Therapy 2012, 14:R70 (29 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Egr-1 contributes to IL-1-mediated down-regulation of peroxisome proliferator-activated receptor γ expression in human osteoarthritic chondrocytes Sarah-Salwa Nebbaki, Fatima El Mansouri, Hassan Afif, Mohit Kapoor, Mohamed Benderdour, Nicolas Duval, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Hassan Fahmi Arthritis Research & Therapy 2012, 14:R69 (28 March 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial Meryl Streep and the problems of clinical trials David A Isenberg Arthritis Research & Therapy 2012, 14:113 (23 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Sustained rheumatoid arthritis remission is uncommon in clinical practice Femke HM Prince, Vivian P Bykerk, Nancy A Shadick, Bing Lu, Jing Cui, Michelle Frits, Christine K Iannaccone, Michael E Weinblatt, Daniel H Solomon Arthritis Research & Therapy 2012, 14:R68 (19 March 2012) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary In clinical practice only a minority of patients with rheumatoid arthritis (RA) are in sustained remission, suggesting strict monitoring is required even once remission is reached.
		Research article Obesity and carotid atherosclerosis in African black and Caucasian women with established rheumatoid arthritis: a cross-sectional study Ahmed Solomon, Gavin R Norton, Angela J Woodiwiss, Patrick H Dessein Arthritis Research & Therapy 2012, 14:R67 (19 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Effect of pregnancy on serum cytokines in SLE patients Andrea Doria, Maurizio Cutolo, Anna Ghirardello, Margherita Zen, Danilo Villalta, Angela Tincani, Leonardo Punzi, Luca Iaccarino, Michelle Petri Arthritis Research & Therapy 2012, 14:R66 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Research article Functional role of IL-22 in psoriatic arthritis Anupam Mitra, Smriti K Raychaudhuri, Siba P Raychaudhuri Arthritis Research & Therapy 2012, 14:R65 (14 March 2012) Abstract \| Full text \| PDF \| PubMed
		Editorial HMGB1: a smoking gun in lupus nephritis? David S Pisetsky Arthritis Research & Therapy 2012, 14:112 (14 March 2012) Abstract \| Full text \| PDF \| PubMed