Arthritis Research & Therapy

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		Research article Oestrogen deficiency modulates particle-induced osteolysis Christophe Nich, Jean Langlois, Arnaud Marchadier, Catherine Vidal, Martine Cohen-Solal, Hervé Petite, Moussa Hamadouche Arthritis Research & Therapy 2011, 13:R100 (22 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study Aamer Sandoo, Douglas Carroll, George S Metsios, George D Kitas, Jet JCS Veldhuijzen van Zanten Arthritis Research & Therapy 2011, 13:R99 (21 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model Maxim Moreau, Pascale Rialland, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Daniel Lajeunesse, Christielle Boileau, Judith Caron, Diane Frank, Bertrand Lussier, Jerome RE del Castillo, Guy Beauchamp, Dominique Gauvin, Thierry Bertaim, Dominique Thibaud, Eric Troncy Arthritis Research & Therapy 2011, 13:R98 (21 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice Anne-Katja Imhof, Laura Glück, Mieczyslaw Gajda, Rolf Bräuer, Hans-Georg Schaible, Stefan Schulz Arthritis Research & Therapy 2011, 13:R97 (20 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis Ulrika Islander, Caroline Jochems, Alexandra Stubelius, Annica Andersson, Marie K Lagerquist, Claes Ohlsson, Hans Carlsten Arthritis Research & Therapy 2011, 13:R96 (20 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Analysis of IL-17⁺cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response Heiner Appel, René Maier, Peihua Wu, Rebecca Scheer, Axel Hempfing, Ralph Kayser, Andreas Thiel, Andreas Radbruch, Christoph Loddenkemper, Joachim Sieper Arthritis Research & Therapy 2011, 13:R95 (20 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Interleukin-17 (IL-17) plays an important role in inflammatory processes in spondyloarthritis, but the innate immune pathway may be of greater relevance than the Th17 mediated adaptive immune response.
		Research article Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational cohort study Suzanne Arends, Elisabeth Brouwer, Eveline van der Veer, Henk Groen, Martha K Leijsma, Pieternella M Houtman, Tim L Th A Jansen, Cees GM Kallenberg, Anneke Spoorenberg Arthritis Research & Therapy 2011, 13:R94 (20 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
		Commentary Systemic sclerosis-associated pulmonary hypertension: why disease-specific composite endpoints are needed Christopher P Denton, Jerome Avouac, Frank Behrens, Daniel E Furst, Ivan Foeldvari, Marc Humbert, Doerte Huscher, Otylia Kowal-Bielecka, Marco Matucci-Cerinic, Peter Nash, Christian F Opitz, David Pittrow, Lewis J Rubin, James R Seibold, Oliver Distler Arthritis Research & Therapy 2011, 13:114 (20 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes Nahid Akhtar, Tariq M Haqqi Arthritis Research & Therapy 2011, 13:R93 (17 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Epigallocatechin-3-gallate, a polyphenol found in green tea, globally suppresses the inflammatory response in human chondrocytes, further supporting its potential as a chondroprotective agent in osteoarthritis.
		Research article Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway Valentina Ulivi, Manuela Lenti, Chiara Gentili, Gabriele Marcolongo, Ranieri Cancedda, Fiorella Descalzi Cancedda Arthritis Research & Therapy 2011, 13:R92 (17 June 2011) Abstract \| Full text \| PDF \| PubMed \| F1000
		Research article Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still's disease: a case-series study Katerina Laskari, Athanasios G Tzioufas, Haralampos M Moutsopoulos Arthritis Research & Therapy 2011, 13:R91 (17 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Hyaluronan modulates accumulation of hypoxia-inducible factor-1 alpha, inducible nitric oxide synthase, and matrix metalloproteinase-3 in the synovium of rat adjuvant-induced arthritis model Li-Wei Chou, John Wang, Pei-Lin Chang, Yueh-Ling Hsieh Arthritis Research & Therapy 2011, 13:R90 (16 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis Hooi-Ming Lee, Hidehiko Sugino, Chieko Aoki, Yasunori Shimaoka, Ryuji Suzuki, Kensuke Ochi, Takahiro Ochi, Norihiro Nishimoto Arthritis Research & Therapy 2011, 13:R89 (16 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Interferon-lambda1 induces peripheral blood mononuclear cell-derived chemokines secretion in patients with systemic lupus erythematosus: its correlation with disease activity Qian Wu, Qingrui Yang, Elaine Lourenco, Hongsheng Sun, Yuanchao Zhang Arthritis Research & Therapy 2011, 13:R88 (16 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Interferon-lambda-1 (IFN-λ1) modulates the expression of chemokines and may be associated with systemic lupus erythematosus (SLE) disease activity, highlighting IFN-λ1 as a potential research target for the pathogenesis and therapy of SLE.
		Research article Predictors for pathologically confirmed aortitis after resection of the ascending aorta: A 12-year Danish nationwide population-based cross-sectional study Jean Schmidt, Kaare Sunesen, Jette B Kornum, Pierre Duhaut, Reimar W Thomsen Arthritis Research & Therapy 2011, 13:R87 (15 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial Lesley M Arnold, Fujun Wang, Jonna Ahl, Paula J Gaynor, Madelaine M Wohlreich Arthritis Research & Therapy 2011, 13:R86 (13 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Duloxetine was found to significantly reduce multiple dimensions of fatigue, pain, anxiety, depressed mood and stiffness in patients suffering from fibromyalgia, with fatigue improvement maintained for up to 24 weeks.
		Review Sjögren's syndrome: studying the disease in mice Nicolas Delaleu, Cuong Q Nguyen, Ammon B Peck, Roland Jonsson Arthritis Research & Therapy 2011, 13:217 (13 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity Jade E Hollis-Moffatt, Peter J Gow, Andrew A Harrison, John Highton, Peter BB Jones, Lisa K Stamp, Nicola Dalbeth, Tony R Merriman Arthritis Research & Therapy 2011, 13:R85 (9 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The usefulness of magnetic resonance imaging of the hand and wrist in very early rheumatoid arthritis Paraskevi E Kosta, Paraskevi V Voulgari, Anastasia K Zikou, Alexandros A Drosos, Maria I Argyropoulou Arthritis Research & Therapy 2011, 13:R84 (9 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Magnetic resonance imaging (MRI) of the hand and wrist may be useful for the detection of bone edema, erosions and synovitis in very early rheumatoid arthritis patients.
		Research article Pain persists in DAS28 rheumatoid arthritis remission but not in ACR/EULAR remission: a longitudinal observational study Yvonne C Lee, Jing Cui, Bing Lu, Michelle L Frits, Christine K Iannaccone, Nancy A Shadick, Michael E Weinblatt, Daniel H Solomon Arthritis Research & Therapy 2011, 13:R83 (8 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Infliximab in ankylosing spondylitis: alone or in combination with methotrexate? A pharmacokinetic comparative study Denis Mulleman, Francine Lauféron, Daniel Wendling, David Ternant, Emilie Ducourau, Gilles Paintaud, Philippe Goupille Arthritis Research & Therapy 2011, 13:R82 (3 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells Devina Purmessur, Rachel M Schek, Rosalyn D Abbott, Bryan A Ballif, Karolyn E Godburn, James C Iatridis Arthritis Research & Therapy 2011, 13:R81 (31 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association: analysis of multiple experiments with lymphoblastoid cell lines Elisa Alonso-Perez, Marian Suarez-Gestal, Manuel Calaza, Tony Kwan, Jacek Majewski, Juan J Gomez-Reino, Antonio Gonzalez Arthritis Research & Therapy 2011, 13:R80 (31 May 2011) Abstract \| Full text \| PDF \| PubMed
		Review Negative regulation of NF-κB and its involvement in rheumatoid arthritis Geert van Loo, Rudi Beyaert Arthritis Research & Therapy 2011, 13:221 (31 May 2011) Abstract \| Full text \| PDF \| PubMed
		Editorial The new era of autoimmune disease research Takao Koike Arthritis Research & Therapy 2011, 13:113 (31 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Videoradiographic analysis of the range of motion in unilateral experimental knee joint arthritis in rats Michael K Boettger, Johannes Leuchtweis, Hans-Georg Schaible, Manuela Schmidt Arthritis Research & Therapy 2011, 13:R79 (27 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Comparisons of 7- to 78-joint ultrasonography scores: all different joint combinations show equal response to adalimumab treatment in patients with rheumatoid arthritis Hilde Hammer, Tore K Kvien Arthritis Research & Therapy 2011, 13:R78 (27 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review MicroRNA biogenesis and regulation of bone remodeling Kristina Kapinas, Anne M Delany Arthritis Research & Therapy 2011, 13:220 (27 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Regulation of bone by the adaptive immune system in arthritis Kazuo Okamoto, Hiroshi Takayanagi Arthritis Research & Therapy 2011, 13:219 (27 May 2011) Abstract \| Full text \| PDF \| PubMed
		Review Aspects of innate immunity in Sjögren's syndrome Hui Low, Torsten Witte Arthritis Research & Therapy 2011, 13:218 (27 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Recent advances in the immunogenetics of idiopathic inflammatory myopathy Hector Chinoy, Janine A Lamb, William ER Ollier, Robert G Cooper Arthritis Research & Therapy 2011, 13:216 (26 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice Kenta Misaki, Akio Morinobu, Jun Saegusa, Shimpei Kasagi, Masaaki Fujita, Yoshiaki Miyamoto, Fumichika Matsuki, Shunichi Kumagai Arthritis Research & Therapy 2011, 13:R77 (18 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis Gabriel N Kaufman, Charlotte Zaouter, Barthélémy Valteau, Pierre Sirois, Florina Moldovan Arthritis Research & Therapy 2011, 13:R76 (16 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID) Hans-Peter Tony, Gerd Burmester, Hendrik Schulze-Koops, Mathias Grunke, Joerg Henes, Ina Kötter, Judith Haas, Leonore Unger, Svjetlana Lovric, Marion Haubitz, Rebecca Fischer-Betz, Gamal Chehab, Andrea Rubbert-Roth, Christof Specker, Jutta Weinerth, Julia Holle, Ulf Müller-Ladner, Ramona König, Christoph Fiehn, Philip Burgwinkel, Klemens Budde, Helmut Sörensen, Michael Meurer, Martin Aringer, Bernd Kieseier, Cornelia Erfurt-Berge, Michael Sticherling, Roland Veelken, Ulf Ziemann, Frank Strutz et al. Arthritis Research & Therapy 2011, 13:R75 (13 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor β pathway in patients with systemic sclerosis Guillaume Bussone, Hanadi Dib, Mathieu C Tamby, Cedric Broussard, Christian Federici, Geneviève Woimant, Luc Camoin, Loïc Guillevin, Luc Mouthon Arthritis Research & Therapy 2011, 13:R74 (13 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Commentary Biosimilars: a regulatory perspective from America Jonathan Kay Arthritis Research & Therapy 2011, 13:112 (12 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Frequent coexistence of anti-topoisomerase I and anti-U1RNP autoantibodies in African American patients associated with mild skin involvement: a retrospective clinical study Minoru Satoh, Malgorzata E Krzyszczak, Yi Li, Angela Ceribelli, Steven J Ross, Edward KL Chan, Mark S Segal, Michael R Bubb, Eric S Sobel, Westley H Reeves Arthritis Research & Therapy 2011, 13:R73 (10 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The relation between cartilage biomarkers (C2C, C1,2C, CS846, and CPII) and the long-term outcome of rheumatoid arthritis patients within the CAMERA trial Marije F Bakker, Suzanne MM Verstappen, Paco MJ Welsing, Johannes WG Jacobs, Zalima N Jahangier, Maaike J van der Veen, Johannes WJ Bijlsma, Floris PJG Lafeber, the Utrecht Arthritis Cohort study group Arthritis Research & Therapy 2011, 13:R70 (8 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes Kiyoshi Migita, Atsumasa Komori, Takafumi Torigoshi, Yumi Maeda, Yasumori Izumi, Yuka Jiuchi, Taiichiro Miyashita, Minoru Nakamura, Satoru Motokawa, Hiromi Ishibashi Arthritis Research & Therapy 2011, 13:R72 (6 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus Deena A Abdulahad, Johanna Westra, Johannes Bijzet, Pieter C Limburg, Cees GM Kallenberg, Marc Bijl Arthritis Research & Therapy 2011, 13:R71 (6 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Biochemical markers of ongoing joint damage in rheumatoid arthritis - current and future applications, limitations and opportunities Morten A Karsdal, Thasia Woodworth, Kim Henriksen, Walter P Maksymowych, Harry Genant, Philippe Vergnaud, Claus Christiansen, Tanja Schubert, Per Qvist, Georg Schett, Adam Platt, Anne-Christine Bay-Jensen Arthritis Research & Therapy 2011, 13:215 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review The role of the central nervous system in the generation and maintenance of chronic pain in rheumatoid arthritis, osteoarthritis and fibromyalgia Yvonne C Lee, Nicholas J Nassikas, Daniel J Clauw Arthritis Research & Therapy 2011, 13:211 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines Hans-Georg Schaible, Andrea Ebersberger, Gabriel Natura Arthritis Research & Therapy 2011, 13:210 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Letter Response to 'Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomized study over 21 months' Miguel A Gonzalez-Gay, Carlos Gonzalez-Juanatey, Jose A Miranda-Filloy, Javier Martin, Maria T Garcia-Unzueta, Javier Llorca Arthritis Research & Therapy 2011, 13:404 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
		Editorial Soluble IL-18 receptor complex: a new star in the firmament of rheumatoid arthritis diagnosis? Fons AJ van de Loo Arthritis Research & Therapy 2011, 13:111 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
		Editorial What do measurements of molecular biomarkers in different body fluids really tell us? A Robin Poole Arthritis Research & Therapy 2011, 13:110 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases Terrance P O'Hanlon, Lisa G Rider, Lu Gan, Rick Fannin, Richard S Paules, David M Umbach, Clarice R Weinberg, Ruchir R Shah, Deepak Mav, Mark F Gourley, Frederick W Miller Arthritis Research & Therapy 2011, 13:R69 (26 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis Kristine L Stump, Lily D Lu, Pawel Dobrzanski, Cynthia Serdikoff, Diane E Gingrich, Ben J Dugan, Thelma S Angeles, Mark S Albom, Mark A Ator, Bruce D Dorsey, Bruce A Ruggeri, Matthew M Seavey Arthritis Research & Therapy 2011, 13:R68 (21 April 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Decrease in the incidence of total hip arthroplasties in patients with rheumatoid arthritis - results from a well defined population in south Sweden Korosh Hekmat, Lennart Jacobsson, Jan-Åke Nilsson, Ingemar F Petersson, Otto Robertsson, Göran Garellick, Carl Turesson Arthritis Research & Therapy 2011, 13:R67 (21 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The incidence of hip arthroplasties decreased significantly after 2001 in a cohort in south Sweden, potentially due to the positive effect on joint damage from more aggressive pharmacological treatment.
		Editorial Antinuclear antibodies in healthy people: the tip of autoimmunity's iceberg? David S Pisetsky Arthritis Research & Therapy 2011, 13:109 (21 April 2011) Abstract \| Full text \| PDF \| PubMed

	All
		Research article Oestrogen deficiency modulates particle-induced osteolysis Christophe Nich, Jean Langlois, Arnaud Marchadier, Catherine Vidal, Martine Cohen-Solal, Hervé Petite, Moussa Hamadouche Arthritis Research & Therapy 2011, 13:R100 (22 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The association between microvascular and macrovascular endothelial function in patients with rheumatoid arthritis: a cross-sectional study Aamer Sandoo, Douglas Carroll, George S Metsios, George D Kitas, Jet JCS Veldhuijzen van Zanten Arthritis Research & Therapy 2011, 13:R99 (21 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model Maxim Moreau, Pascale Rialland, Jean-Pierre Pelletier, Johanne Martel-Pelletier, Daniel Lajeunesse, Christielle Boileau, Judith Caron, Diane Frank, Bertrand Lussier, Jerome RE del Castillo, Guy Beauchamp, Dominique Gauvin, Thierry Bertaim, Dominique Thibaud, Eric Troncy Arthritis Research & Therapy 2011, 13:R98 (21 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Potent anti-inflammatory and antinociceptive activity of the endothelin receptor antagonist bosentan in monoarthritic mice Anne-Katja Imhof, Laura Glück, Mieczyslaw Gajda, Rolf Bräuer, Hans-Georg Schaible, Stefan Schulz Arthritis Research & Therapy 2011, 13:R97 (20 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Combined treatment with dexamethasone and raloxifene totally abrogates osteoporosis and joint destruction in experimental postmenopausal arthritis Ulrika Islander, Caroline Jochems, Alexandra Stubelius, Annica Andersson, Marie K Lagerquist, Claes Ohlsson, Hans Carlsten Arthritis Research & Therapy 2011, 13:R96 (20 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Analysis of IL-17⁺cells in facet joints of patients with spondyloarthritis suggests that the innate immune pathway might be of greater relevance than the Th17-mediated adaptive immune response Heiner Appel, René Maier, Peihua Wu, Rebecca Scheer, Axel Hempfing, Ralph Kayser, Andreas Thiel, Andreas Radbruch, Christoph Loddenkemper, Joachim Sieper Arthritis Research & Therapy 2011, 13:R95 (20 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Interleukin-17 (IL-17) plays an important role in inflammatory processes in spondyloarthritis, but the innate immune pathway may be of greater relevance than the Th17 mediated adaptive immune response.
		Research article Baseline predictors of response and discontinuation of tumor necrosis factor-alpha blocking therapy in ankylosing spondylitis: a prospective longitudinal observational cohort study Suzanne Arends, Elisabeth Brouwer, Eveline van der Veer, Henk Groen, Martha K Leijsma, Pieternella M Houtman, Tim L Th A Jansen, Cees GM Kallenberg, Anneke Spoorenberg Arthritis Research & Therapy 2011, 13:R94 (20 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000
		Commentary Systemic sclerosis-associated pulmonary hypertension: why disease-specific composite endpoints are needed Christopher P Denton, Jerome Avouac, Frank Behrens, Daniel E Furst, Ivan Foeldvari, Marc Humbert, Doerte Huscher, Otylia Kowal-Bielecka, Marco Matucci-Cerinic, Peter Nash, Christian F Opitz, David Pittrow, Lewis J Rubin, James R Seibold, Oliver Distler Arthritis Research & Therapy 2011, 13:114 (20 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Epigallocatechin-3-gallate suppresses the global interleukin-1beta-induced inflammatory response in human chondrocytes Nahid Akhtar, Tariq M Haqqi Arthritis Research & Therapy 2011, 13:R93 (17 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Epigallocatechin-3-gallate, a polyphenol found in green tea, globally suppresses the inflammatory response in human chondrocytes, further supporting its potential as a chondroprotective agent in osteoarthritis.
		Research article Anti-inflammatory activity of monogalactosyldiacylglycerol in human articular cartilage in vitro: activation of an anti-inflammatory cyclooxygenase-2 (COX-2) pathway Valentina Ulivi, Manuela Lenti, Chiara Gentili, Gabriele Marcolongo, Ranieri Cancedda, Fiorella Descalzi Cancedda Arthritis Research & Therapy 2011, 13:R92 (17 June 2011) Abstract \| Full text \| PDF \| PubMed \| F1000
		Research article Efficacy and long-term follow-up of IL-1R inhibitor anakinra in adults with Still's disease: a case-series study Katerina Laskari, Athanasios G Tzioufas, Haralampos M Moutsopoulos Arthritis Research & Therapy 2011, 13:R91 (17 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Hyaluronan modulates accumulation of hypoxia-inducible factor-1 alpha, inducible nitric oxide synthase, and matrix metalloproteinase-3 in the synovium of rat adjuvant-induced arthritis model Li-Wei Chou, John Wang, Pei-Lin Chang, Yueh-Ling Hsieh Arthritis Research & Therapy 2011, 13:R90 (16 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Abnormal networks of immune response-related molecules in bone marrow cells from patients with rheumatoid arthritis as revealed by DNA microarray analysis Hooi-Ming Lee, Hidehiko Sugino, Chieko Aoki, Yasunori Shimaoka, Ryuji Suzuki, Kensuke Ochi, Takahiro Ochi, Norihiro Nishimoto Arthritis Research & Therapy 2011, 13:R89 (16 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Interferon-lambda1 induces peripheral blood mononuclear cell-derived chemokines secretion in patients with systemic lupus erythematosus: its correlation with disease activity Qian Wu, Qingrui Yang, Elaine Lourenco, Hongsheng Sun, Yuanchao Zhang Arthritis Research & Therapy 2011, 13:R88 (16 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Interferon-lambda-1 (IFN-λ1) modulates the expression of chemokines and may be associated with systemic lupus erythematosus (SLE) disease activity, highlighting IFN-λ1 as a potential research target for the pathogenesis and therapy of SLE.
		Research article Predictors for pathologically confirmed aortitis after resection of the ascending aorta: A 12-year Danish nationwide population-based cross-sectional study Jean Schmidt, Kaare Sunesen, Jette B Kornum, Pierre Duhaut, Reimar W Thomsen Arthritis Research & Therapy 2011, 13:R87 (15 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Improvement in multiple dimensions of fatigue in patients with fibromyalgia treated with duloxetine: secondary analysis of a randomized, placebo-controlled trial Lesley M Arnold, Fujun Wang, Jonna Ahl, Paula J Gaynor, Madelaine M Wohlreich Arthritis Research & Therapy 2011, 13:R86 (13 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Duloxetine was found to significantly reduce multiple dimensions of fatigue, pain, anxiety, depressed mood and stiffness in patients suffering from fibromyalgia, with fatigue improvement maintained for up to 24 weeks.
		Review Sjögren's syndrome: studying the disease in mice Nicolas Delaleu, Cuong Q Nguyen, Ammon B Peck, Roland Jonsson Arthritis Research & Therapy 2011, 13:217 (13 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article The SLC2A9 nonsynonymous Arg265His variant and gout: evidence for a population-specific effect on severity Jade E Hollis-Moffatt, Peter J Gow, Andrew A Harrison, John Highton, Peter BB Jones, Lisa K Stamp, Nicola Dalbeth, Tony R Merriman Arthritis Research & Therapy 2011, 13:R85 (9 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The usefulness of magnetic resonance imaging of the hand and wrist in very early rheumatoid arthritis Paraskevi E Kosta, Paraskevi V Voulgari, Anastasia K Zikou, Alexandros A Drosos, Maria I Argyropoulou Arthritis Research & Therapy 2011, 13:R84 (9 June 2011) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Magnetic resonance imaging (MRI) of the hand and wrist may be useful for the detection of bone edema, erosions and synovitis in very early rheumatoid arthritis patients.
		Research article Pain persists in DAS28 rheumatoid arthritis remission but not in ACR/EULAR remission: a longitudinal observational study Yvonne C Lee, Jing Cui, Bing Lu, Michelle L Frits, Christine K Iannaccone, Nancy A Shadick, Michael E Weinblatt, Daniel H Solomon Arthritis Research & Therapy 2011, 13:R83 (8 June 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Infliximab in ankylosing spondylitis: alone or in combination with methotrexate? A pharmacokinetic comparative study Denis Mulleman, Francine Lauféron, Daniel Wendling, David Ternant, Emilie Ducourau, Gilles Paintaud, Philippe Goupille Arthritis Research & Therapy 2011, 13:R82 (3 June 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Notochordal conditioned media from tissue increases proteoglycan accumulation and promotes a healthy nucleus pulposus phenotype in human mesenchymal stem cells Devina Purmessur, Rachel M Schek, Rosalyn D Abbott, Bryan A Ballif, Karolyn E Godburn, James C Iatridis Arthritis Research & Therapy 2011, 13:R81 (31 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Cis-regulation of IRF5 expression is unable to fully account for systemic lupus erythematosus association: analysis of multiple experiments with lymphoblastoid cell lines Elisa Alonso-Perez, Marian Suarez-Gestal, Manuel Calaza, Tony Kwan, Jacek Majewski, Juan J Gomez-Reino, Antonio Gonzalez Arthritis Research & Therapy 2011, 13:R80 (31 May 2011) Abstract \| Full text \| PDF \| PubMed
		Review Negative regulation of NF-κB and its involvement in rheumatoid arthritis Geert van Loo, Rudi Beyaert Arthritis Research & Therapy 2011, 13:221 (31 May 2011) Abstract \| Full text \| PDF \| PubMed
		Editorial The new era of autoimmune disease research Takao Koike Arthritis Research & Therapy 2011, 13:113 (31 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Videoradiographic analysis of the range of motion in unilateral experimental knee joint arthritis in rats Michael K Boettger, Johannes Leuchtweis, Hans-Georg Schaible, Manuela Schmidt Arthritis Research & Therapy 2011, 13:R79 (27 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Comparisons of 7- to 78-joint ultrasonography scores: all different joint combinations show equal response to adalimumab treatment in patients with rheumatoid arthritis Hilde Hammer, Tore K Kvien Arthritis Research & Therapy 2011, 13:R78 (27 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review MicroRNA biogenesis and regulation of bone remodeling Kristina Kapinas, Anne M Delany Arthritis Research & Therapy 2011, 13:220 (27 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Regulation of bone by the adaptive immune system in arthritis Kazuo Okamoto, Hiroshi Takayanagi Arthritis Research & Therapy 2011, 13:219 (27 May 2011) Abstract \| Full text \| PDF \| PubMed
		Review Aspects of innate immunity in Sjögren's syndrome Hui Low, Torsten Witte Arthritis Research & Therapy 2011, 13:218 (27 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Recent advances in the immunogenetics of idiopathic inflammatory myopathy Hector Chinoy, Janine A Lamb, William ER Ollier, Robert G Cooper Arthritis Research & Therapy 2011, 13:216 (26 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article Histone deacetylase inhibition alters dendritic cells to assume a tolerogenic phenotype and ameliorates arthritis in SKG mice Kenta Misaki, Akio Morinobu, Jun Saegusa, Shimpei Kasagi, Masaaki Fujita, Yoshiaki Miyamoto, Fumichika Matsuki, Shunichi Kumagai Arthritis Research & Therapy 2011, 13:R77 (18 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Nociceptive tolerance is improved by bradykinin receptor B1 antagonism and joint morphology is protected by both endothelin type A and bradykinin receptor B1 antagonism in a surgical model of osteoarthritis Gabriel N Kaufman, Charlotte Zaouter, Barthélémy Valteau, Pierre Sirois, Florina Moldovan Arthritis Research & Therapy 2011, 13:R76 (16 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID) Hans-Peter Tony, Gerd Burmester, Hendrik Schulze-Koops, Mathias Grunke, Joerg Henes, Ina Kötter, Judith Haas, Leonore Unger, Svjetlana Lovric, Marion Haubitz, Rebecca Fischer-Betz, Gamal Chehab, Andrea Rubbert-Roth, Christof Specker, Jutta Weinerth, Julia Holle, Ulf Müller-Ladner, Ramona König, Christoph Fiehn, Philip Burgwinkel, Klemens Budde, Helmut Sörensen, Michael Meurer, Martin Aringer, Bernd Kieseier, Cornelia Erfurt-Berge, Michael Sticherling, Roland Veelken, Ulf Ziemann, Frank Strutz et al. Arthritis Research & Therapy 2011, 13:R75 (13 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Identification of new autoantibody specificities directed at proteins involved in the transforming growth factor β pathway in patients with systemic sclerosis Guillaume Bussone, Hanadi Dib, Mathieu C Tamby, Cedric Broussard, Christian Federici, Geneviève Woimant, Luc Camoin, Loïc Guillevin, Luc Mouthon Arthritis Research & Therapy 2011, 13:R74 (13 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Commentary Biosimilars: a regulatory perspective from America Jonathan Kay Arthritis Research & Therapy 2011, 13:112 (12 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Frequent coexistence of anti-topoisomerase I and anti-U1RNP autoantibodies in African American patients associated with mild skin involvement: a retrospective clinical study Minoru Satoh, Malgorzata E Krzyszczak, Yi Li, Angela Ceribelli, Steven J Ross, Edward KL Chan, Mark S Segal, Michael R Bubb, Eric S Sobel, Westley H Reeves Arthritis Research & Therapy 2011, 13:R73 (10 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article The relation between cartilage biomarkers (C2C, C1,2C, CS846, and CPII) and the long-term outcome of rheumatoid arthritis patients within the CAMERA trial Marije F Bakker, Suzanne MM Verstappen, Paco MJ Welsing, Johannes WG Jacobs, Zalima N Jahangier, Maaike J van der Veen, Johannes WJ Bijlsma, Floris PJG Lafeber, the Utrecht Arthritis Cohort study group Arthritis Research & Therapy 2011, 13:R70 (8 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article CP690,550 inhibits oncostatin M-induced JAK/STAT signaling pathway in rheumatoid synoviocytes Kiyoshi Migita, Atsumasa Komori, Takafumi Torigoshi, Yumi Maeda, Yasumori Izumi, Yuka Jiuchi, Taiichiro Miyashita, Minoru Nakamura, Satoru Motokawa, Hiromi Ishibashi Arthritis Research & Therapy 2011, 13:R72 (6 May 2011) Abstract \| Full text \| PDF \| PubMed
		Research article High mobility group box 1 (HMGB1) and anti-HMGB1 antibodies and their relation to disease characteristics in systemic lupus erythematosus Deena A Abdulahad, Johanna Westra, Johannes Bijzet, Pieter C Limburg, Cees GM Kallenberg, Marc Bijl Arthritis Research & Therapy 2011, 13:R71 (6 May 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Biochemical markers of ongoing joint damage in rheumatoid arthritis - current and future applications, limitations and opportunities Morten A Karsdal, Thasia Woodworth, Kim Henriksen, Walter P Maksymowych, Harry Genant, Philippe Vergnaud, Claus Christiansen, Tanja Schubert, Per Qvist, Georg Schett, Adam Platt, Anne-Christine Bay-Jensen Arthritis Research & Therapy 2011, 13:215 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review The role of the central nervous system in the generation and maintenance of chronic pain in rheumatoid arthritis, osteoarthritis and fibromyalgia Yvonne C Lee, Nicholas J Nassikas, Daniel J Clauw Arthritis Research & Therapy 2011, 13:211 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Review Update on peripheral mechanisms of pain: beyond prostaglandins and cytokines Hans-Georg Schaible, Andrea Ebersberger, Gabriel Natura Arthritis Research & Therapy 2011, 13:210 (28 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Letter Response to 'Infliximab therapy increases body fat mass in early rheumatoid arthritis independently of changes in disease activity and levels of leptin and adiponectin: a randomized study over 21 months' Miguel A Gonzalez-Gay, Carlos Gonzalez-Juanatey, Jose A Miranda-Filloy, Javier Martin, Maria T Garcia-Unzueta, Javier Llorca Arthritis Research & Therapy 2011, 13:404 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
		Editorial Soluble IL-18 receptor complex: a new star in the firmament of rheumatoid arthritis diagnosis? Fons AJ van de Loo Arthritis Research & Therapy 2011, 13:111 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
		Editorial What do measurements of molecular biomarkers in different body fluids really tell us? A Robin Poole Arthritis Research & Therapy 2011, 13:110 (27 April 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Gene expression profiles from discordant monozygotic twins suggest that molecular pathways are shared among multiple systemic autoimmune diseases Terrance P O'Hanlon, Lisa G Rider, Lu Gan, Rick Fannin, Richard S Paules, David M Umbach, Clarice R Weinberg, Ruchir R Shah, Deepak Mav, Mark F Gourley, Frederick W Miller Arthritis Research & Therapy 2011, 13:R69 (26 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
		Research article A highly selective, orally active inhibitor of Janus kinase 2, CEP-33779, ablates disease in two mouse models of rheumatoid arthritis Kristine L Stump, Lily D Lu, Pawel Dobrzanski, Cynthia Serdikoff, Diane E Gingrich, Ben J Dugan, Thelma S Angeles, Mark S Albom, Mark A Ator, Bruce D Dorsey, Bruce A Ruggeri, Matthew M Seavey Arthritis Research & Therapy 2011, 13:R68 (21 April 2011) Abstract \| Full text \| PDF \| PubMed
		Research article Decrease in the incidence of total hip arthroplasties in patients with rheumatoid arthritis - results from a well defined population in south Sweden Korosh Hekmat, Lennart Jacobsson, Jan-Åke Nilsson, Ingemar F Petersson, Otto Robertsson, Göran Garellick, Carl Turesson Arthritis Research & Therapy 2011, 13:R67 (21 April 2011) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary The incidence of hip arthroplasties decreased significantly after 2001 in a cohort in south Sweden, potentially due to the positive effect on joint damage from more aggressive pharmacological treatment.
		Editorial Antinuclear antibodies in healthy people: the tip of autoimmunity's iceberg? David S Pisetsky Arthritis Research & Therapy 2011, 13:109 (21 April 2011) Abstract \| Full text \| PDF \| PubMed