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Autophagy in rat annulus fibrosus cells: evidence and possible implications
Chao Shen, Jun Yan, Lei-Sheng Jiang, Li-Yang Dai Arthritis Research & Therapy 2011, 13:R132 (16 August 2011)
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Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study
Lena Innala, Bozena Möller, Lotta Ljung, Staffan Magnusson, Torgny Smedby, Anna Södergren, Marie-Louise Öhman, Solbritt Rantapää-Dahlqvist, Solveig Wållberg-Jonsson Arthritis Research & Therapy 2011, 13:R131 (15 August 2011)
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Editor’s summary
The occurrence of heart disease in patients with rheumatoid arthritis (RA) is potentiated by disease-related inflammation as well as traditional risk factors, which may have implications for cardioprotective strategies in RA.
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A new weapon against an old target
Christoph Fiehn Arthritis Research & Therapy 2011, 13:122 (12 August 2011)
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Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes
Dongyao Yan, Di Chen, Simon M Cool, Andre J van Wijnen, Katalin Mikecz, Gillian Murphy, Hee-Jeong Im Arthritis Research & Therapy 2011, 13:R130 (11 August 2011)
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Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts
Emily Turner-Brannen, Ka-Yee Choi, Dustin ND Lippert, John P Cortens, Robert EW Hancock, Hani El-Gabalawy, Neeloffer Mookherjee Arthritis Research & Therapy 2011, 13:R129 (11 August 2011)
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Green tea: a new option for the prevention or control of osteoarthritis
Santosh K Katiyar, Chander Raman Arthritis Research & Therapy 2011, 13:121 (10 August 2011)
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Decreased catalytic function with altered sumoylation of DNA topoisomerase I in the nuclei of scleroderma fibroblasts
Xiaodong Zhou, Wei Lin, Filemon K Tan, Shervin Assassi, Mavin J Fritzler, Xinjian Guo, Roozbeh Sharif, Tom Xia, Syeling Lai, Frank C Arnett Arthritis Research & Therapy 2011, 13:R128 (9 August 2011)
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Postural control deficits in people with fibromyalgia: a pilot study
Kim D Jones, Laurie A King, Scott D Mist, Robert M Bennett, Fay B Horak Arthritis Research & Therapy 2011, 13:R127 (2 August 2011)
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Giant cell arteritis: immune and vascular aging as disease risk factors
Shalini V Mohan, Y Joyce Liao, Jonathan W Kim, Jörg J Goronzy, Cornelia M Weyand Arthritis Research & Therapy 2011, 13:231 (2 August 2011)
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Are we ready for therapeutic drug monitoring of biologic therapeutics?
Charlotte LM Krieckaert, Willem F Lems Arthritis Research & Therapy 2011, 13:120 (2 August 2011)
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Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy
Der-Yuan Chen, Yi-Ming Chen, Hsin-Hua Chen, Chia-Wei Hsieh, Chi-Chen Lin, Joung-Liang Lan Arthritis Research & Therapy 2011, 13:R126 (30 July 2011)
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A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee
Stanley B Cohen, Susanna Proudman, Alan J Kivitz, Francis X Burch, John P Donohue, Deborah Burstein, Yu-Nien Sun, Christopher Banfield, Michael S Vincent, Liyun Ni, Debra J Zack Arthritis Research & Therapy 2011, 13:R125 (29 July 2011)
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Investigating a pathogenic role for TXNDC5 in rheumatoid arthritis
Xiaotian Chang, Yan Zhao, Xinfeng Yan, Jihong Pan, Kehua Fang, Lin Wang Arthritis Research & Therapy 2011, 13:R124 (29 July 2011)
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Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis
Tobias Braun, Jochen Zwerina Arthritis Research & Therapy 2011, 13:235 (28 July 2011)
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Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors
Baohong Zhao, Lionel B Ivashkiv Arthritis Research & Therapy 2011, 13:234 (28 July 2011)
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A targeted lipidomics approach to the study of eicosanoid release in synovial joints
Janny C de Grauw, Chris HA van de Lest, Paul van Weeren Arthritis Research & Therapy 2011, 13:R123 (27 July 2011)
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Decreases in serum levels of S100A8/9 (calprotectin) correlate with improvements in total swollen joint count in patients with recent-onset rheumatoid arthritis
Lucie Andrés Cerezo, Heřman Mann, Ondřej Pecha, Lenka Pleštilová, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt Arthritis Research & Therapy 2011, 13:R122 (26 July 2011)
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Lymphotoxin α revisited: general features and implications in rheumatoid arthritis
Flavia Calmon-Hamaty, Bernard Combe, Michael Hahne, Jacques Morel Arthritis Research & Therapy 2011, 13:232 (26 July 2011)
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Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis
Monika Biniecka, Aisling Kennedy, Chin T Ng, Ting C Chang, Emese Balogh, Edward Fox, Douglas J Veale, Ursula Fearon, Jacintha N O'Sullivan Arthritis Research & Therapy 2011, 13:R121 (25 July 2011)
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The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration
Fackson Mwale, Koichi Masuda, Rajeswari Pichika, Laura M Epure, Tomoaki Yoshikawa, Aseem Hemmad, Peter J Roughley, John Antoniou Arthritis Research & Therapy 2011, 13:R120 (25 July 2011)
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Atypical clinical presentation of a subset of patients with anti-RNA polymerase III - non-scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining
Angela Ceribelli, Malgorzata E Krzyszczak, Yi Li, Steven J Ross, Jason YF Chan, Edward KL Chan, Rufus W Burlingame, Tyler T Webb, Michael R Bubb, Eric S Sobel, Westley H Reeves, Minoru Satoh Arthritis Research & Therapy 2011, 13:R119 (22 July 2011)
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Idiopathic aortitis: an underrecognized vasculitis
Nicolò Pipitone, Carlo Salvarani Arthritis Research & Therapy 2011, 13:119 (22 July 2011)
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Single-step autoantibody profiling in antiphospholipid syndrome using a multi-line dot assay
Karl Egerer, Dirk Roggenbuck, Thomas Büttner, Barbara Lehmann, Annushka Kohn, Philipp von Landenberg, Rico Hiemann, Eugen Feist, Gerd-Rüdiger Burmester, Thomas Dörner Arthritis Research & Therapy 2011, 13:R118 (21 July 2011)
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Influence of atorvastatin on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients: a prospective, randomized, double-masked, placebo-controlled study
Wojciech Plazak, Krzysztof Gryga, Hanna Dziedzic, Lidia Tomkiewicz-Pajak, Malgorzata Konieczynska, Piotr Podolec, Jacek Musial Arthritis Research & Therapy 2011, 13:R117 (20 July 2011)
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Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients
María Teruel, Jose-Ezequiel Martin, Carlos González-Juanatey, Raquel López-Mejias, Jose A Miranda-Filloy, Ricardo Blanco, Alejandro Balsa, Dora Pascual-Salcedo, Luis Rodriguez-Rodriguez, Benjamin Fernández-Gutierrez, Ana M Ortiz, Isidoro González-Alvaro, Carmen Gómez-Vaquero, Nunzio Bottini, Javier Llorca, Miguel A González-Gay, Javier Martin Arthritis Research & Therapy 2011, 13:R116 (18 July 2011)
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The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells
Betty Y Chang, Min Huang, Michelle Francesco, Jun Chen, Jeremy Sokolove, Padmaja Magadala, William H Robinson, Joseph J Buggy Arthritis Research & Therapy 2011, 13:R115 (13 July 2011)
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The lung as a possible target for the immune reaction in myositis
Sonye K Danoff, Livia Casciola-Rosen Arthritis Research & Therapy 2011, 13:230 (13 July 2011)
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MicroRNAs in systemic rheumatic diseases
Angela Ceribelli, Bing Yao, Paul R Dominguez-Gutierrez, Md A Nahid, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2011, 13:229 (13 July 2011)
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Characterization of a novel and spontaneous mouse model of inflammatory arthritis
Iris A Adipue, Joel T Wilcox, Cody King, Carolyn AY Rice, Katherine M Shaum, Cory M Suard, Elri Brink, Stephen D Miller, Eileen J McMahon Arthritis Research & Therapy 2011, 13:R114 (12 July 2011)
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The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1
Yu-Jung Heo, Hye-Jwa Oh, Young Jung, Mi-La Cho, Seon-Yeong Lee, Jun-Geol Yu, Mi-Kyung Park, Hae-Rim Kim, Sang-Heon Lee, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2011, 13:R113 (12 July 2011)
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Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label
Cándido Díaz-Lagares, Roberto Pérez-Alvarez, Francisco J García-Hernández, María M Ayala-Gutiérrez, José Callejas, Agustín Martínez-Berriotxoa, Javier Rascón, Luis Caminal-Montero, Albert Selva-O'Callaghan, Joaquim Oristrell, Carmen Hidalgo, Ricardo Gómez-de-la-Torre, Luis Sáez, Jesús Canora-Lebrato, María-Teresa Camps, Norberto Ortego-Centeno, María-Jesús Castillo-Palma, Manuel Ramos-Casals, the BIOGEAS Study Group Arthritis Research & Therapy 2011, 13:R112 (11 July 2011)
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Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis
Fulvia Ceccarelli, Carlo Perricone, Martina Fabris, Cristiano Alessandri, Annamaria Iagnocco, Cinzia Fabro, Elena Pontarini, Salvatore De Vita, Guido Valesini Arthritis Research & Therapy 2011, 13:R111 (8 July 2011)
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Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain
Michael Boettger, Diana Kümmel, Andrew Harrison, Hans-Georg Schaible Arthritis Research & Therapy 2011, 13:R110 (7 July 2011)
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Cytokine disturbances in systemic lupus erythematosus
Noam Jacob, William Stohl Arthritis Research & Therapy 2011, 13:228 (6 July 2011)
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Disturbance of cytokine networks in Sjögren's syndrome
Pierre Youinou, Jacques-Olivier Pers Arthritis Research & Therapy 2011, 13:227 (6 July 2011)
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Neutrophils and interferon-α-producing cells: who produces interferon in lupus?
Patrice Decker Arthritis Research & Therapy 2011, 13:118 (6 July 2011)
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Liver involvement in subjects with rheumatic disease
Carlo Selmi, Maria De Santis, M Eric Gershwin Arthritis Research & Therapy 2011, 13:226 (30 June 2011)
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Cardiovascular co-morbidity in patients with rheumatic diseases
Johan Frostegård Arthritis Research & Therapy 2011, 13:225 (30 June 2011)
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Conditions in subjects with rheumatic diseases: pulmonary manifestations of vasculitides
Julia U Holle, Frank Moosig, Klaus Dalhoff, Wolfgang L Gross Arthritis Research & Therapy 2011, 13:224 (30 June 2011)
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Fibromyalgia, myofascial pain, tender points and trigger points: splitting or lumping?
Robert M Bennett, Don L Goldenberg Arthritis Research & Therapy 2011, 13:117 (30 June 2011)
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Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects
Kaspar R Nielsen, Rudi Steffensen, Martin Boegsted, John Baech, Soeren Lundbye-Christensen, Merete L Hetland, Sophine B Krintel, Hans E Johnsen, Mette Nyegaard, Julia S Johansen Arthritis Research & Therapy 2011, 13:R109 (29 June 2011)
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Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis
George S Metsios, Antonios Stavropoulos-Kalinoglou, Gareth J Treharne, Alan M Nevill, Aamer Sandoo, Vasileios F Panoulas, Tracey E Toms, Yiannis Koutedakis, George D Kitas Arthritis Research & Therapy 2011, 13:R108 (29 June 2011)
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Editor’s summary
Physical activity and disease activity are important predictors of hospital admissions and length of hospitalisation in rheumatoid arthritis patients, suggesting lifestyle changes combined with effective pharmacological therapy may improve health and economic outcomes.
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Treating rheumatic patients with a malignancy
Katarzyna Elandt, Daniel Aletaha Arthritis Research & Therapy 2011, 13:223 (29 June 2011)
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Renal co-morbidity in patients with rheumatic diseases
Hans-Joachim Anders, Volker Vielhauer Arthritis Research & Therapy 2011, 13:222 (29 June 2011)
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Considering comorbidity in managing rheumatic diseases: going where trials cannot go
Daniel Aletaha, Thomas Dörner Arthritis Research & Therapy 2011, 13:116 (29 June 2011)
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Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach
Alexis Régent, Hanadi Dib, Kim H Ly, Christian Agard, Mathieu C Tamby, Nicolas Tamas, Babette Weksler, Christian Federici, Cédric Broussard, Loïc Guillevin, Luc Mouthon Arthritis Research & Therapy 2011, 13:R107 (28 June 2011)
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Defective response of CD4+ T cells to retinoic acid and TGFβ in systemic lupus erythematosus
Eric S Sobel, Todd M Brusko, Ed J Butfiloski, Wei Hou, Shiwu Li, Carla M Cuda, Ariana N Abid, Westley H Reeves, Laurence Morel Arthritis Research & Therapy 2011, 13:R106 (27 June 2011)
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Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases
Emilie Ducourau, Denis Mulleman, Gilles Paintaud, Delphine Miow Lin, Francine Lauféron, David Ternant, Hervé Watier, Philippe Goupille Arthritis Research & Therapy 2011, 13:R105 (27 June 2011)
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Editor’s summary
High initial serum concentration of infliximab reduces the development of antibodies towards infliximab (ATI) and absence of ATI may be associated with prolonged maintenance of infliximab, suggesting infliximab serum concentrations should be monitored early.
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Potential role and mechanism of IFN-gamma inducible protein-10 on receptor activator of nuclear factor kappa-B ligand (RANKL) expression in rheumatoid arthritis
Eun Lee, MiRan Seo, Yong-Sung Juhnn, Jeong Kim, Yoo Hong, Yun Lee, Eun Lee, Yeong Song Arthritis Research & Therapy 2011, 13:R104 (27 June 2011)
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Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts
Wenhua Zhu, Liesu Meng, Congshan Jiang, Xiaojing He, Weikun Hou, Peng Xu, Heng Du, Rikard Holmdahl, Shemin Lu Arthritis Research & Therapy 2011, 13:R103 (27 June 2011)
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