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Page 12 of 58

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Research article   Open Access

Autophagy in rat annulus fibrosus cells: evidence and possible implications

Chao Shen, Jun Yan, Lei-Sheng Jiang, Li-Yang Dai Arthritis Research & Therapy 2011, 13:R132 (16 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Cardiovascular events in early RA are a result of inflammatory burden and traditional risk factors: a five year prospective study

Lena Innala, Bozena Möller, Lotta Ljung, Staffan Magnusson, Torgny Smedby, Anna Södergren, Marie-Louise Öhman, Solbritt Rantapää-Dahlqvist, Solveig Wållberg-Jonsson Arthritis Research & Therapy 2011, 13:R131 (15 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The occurrence of heart disease in patients with rheumatoid arthritis (RA) is potentiated by disease-related inflammation as well as traditional risk factors, which may have implications for cardioprotective strategies in RA.

Editorial   Free Highly Accessed

A new weapon against an old target

Christoph Fiehn Arthritis Research & Therapy 2011, 13:122 (12 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

Dongyao Yan, Di Chen, Simon M Cool, Andre J van Wijnen, Katalin Mikecz, Gillian Murphy, Hee-Jeong Im Arthritis Research & Therapy 2011, 13:R130 (11 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Modulation of interleukin-1β-induced inflammatory responses by a synthetic cationic innate defence regulator peptide, IDR-1002, in synovial fibroblasts

Emily Turner-Brannen, Ka-Yee Choi, Dustin ND Lippert, John P Cortens, Robert EW Hancock, Hani El-Gabalawy, Neeloffer Mookherjee Arthritis Research & Therapy 2011, 13:R129 (11 August 2011)

Abstract | Full text | PDF | PubMed

Editorial   Free Highly Accessed

Green tea: a new option for the prevention or control of osteoarthritis

Santosh K Katiyar, Chander Raman Arthritis Research & Therapy 2011, 13:121 (10 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Decreased catalytic function with altered sumoylation of DNA topoisomerase I in the nuclei of scleroderma fibroblasts

Xiaodong Zhou, Wei Lin, Filemon K Tan, Shervin Assassi, Mavin J Fritzler, Xinjian Guo, Roozbeh Sharif, Tom Xia, Syeling Lai, Frank C Arnett Arthritis Research & Therapy 2011, 13:R128 (9 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Postural control deficits in people with fibromyalgia: a pilot study

Kim D Jones, Laurie A King, Scott D Mist, Robert M Bennett, Fay B Horak Arthritis Research & Therapy 2011, 13:R127 (2 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Free

Giant cell arteritis: immune and vascular aging as disease risk factors

Shalini V Mohan, Y Joyce Liao, Jonathan W Kim, Jörg J Goronzy, Cornelia M Weyand Arthritis Research & Therapy 2011, 13:231 (2 August 2011)

Abstract | Full text | PDF | PubMed

Editorial   Free

Are we ready for therapeutic drug monitoring of biologic therapeutics?

Charlotte LM Krieckaert, Willem F Lems Arthritis Research & Therapy 2011, 13:120 (2 August 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Increasing levels of circulating Th17 cells and interleukin-17 in rheumatoid arthritis patients with an inadequate response to anti-TNF-α therapy

Der-Yuan Chen, Yi-Ming Chen, Hsin-Hua Chen, Chia-Wei Hsieh, Chi-Chen Lin, Joung-Liang Lan Arthritis Research & Therapy 2011, 13:R126 (30 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL-1R1) in patients with osteoarthritis of the knee

Stanley B Cohen, Susanna Proudman, Alan J Kivitz, Francis X Burch, John P Donohue, Deborah Burstein, Yu-Nien Sun, Christopher Banfield, Michael S Vincent, Liyun Ni, Debra J Zack Arthritis Research & Therapy 2011, 13:R125 (29 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Investigating a pathogenic role for TXNDC5 in rheumatoid arthritis

Xiaotian Chang, Yan Zhao, Xinfeng Yan, Jihong Pan, Kehua Fang, Lin Wang Arthritis Research & Therapy 2011, 13:R124 (29 July 2011)

Abstract | Full text | PDF | PubMed

Review   Free

Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis

Tobias Braun, Jochen Zwerina Arthritis Research & Therapy 2011, 13:235 (28 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Free

Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors

Baohong Zhao, Lionel B Ivashkiv Arthritis Research & Therapy 2011, 13:234 (28 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

A targeted lipidomics approach to the study of eicosanoid release in synovial joints

Janny C de Grauw, Chris HA van de Lest, Paul van Weeren Arthritis Research & Therapy 2011, 13:R123 (27 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Decreases in serum levels of S100A8/9 (calprotectin) correlate with improvements in total swollen joint count in patients with recent-onset rheumatoid arthritis

Lucie Andrés Cerezo, Heřman Mann, Ondřej Pecha, Lenka Pleštilová, Karel Pavelka, Jiří Vencovský, Ladislav Šenolt Arthritis Research & Therapy 2011, 13:R122 (26 July 2011)

Abstract | Full text | PDF | PubMed

Review   Free

Lymphotoxin α revisited: general features and implications in rheumatoid arthritis

Flavia Calmon-Hamaty, Bernard Combe, Michael Hahne, Jacques Morel Arthritis Research & Therapy 2011, 13:232 (26 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxia-induced mitochondrial mutagenesis in inflammatory arthritis

Monika Biniecka, Aisling Kennedy, Chin T Ng, Ting C Chang, Emese Balogh, Edward Fox, Douglas J Veale, Ursula Fearon, Jacintha N O'Sullivan Arthritis Research & Therapy 2011, 13:R121 (25 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

The efficacy of Link N as a mediator of repair in a rabbit model of intervertebral disc degeneration

Fackson Mwale, Koichi Masuda, Rajeswari Pichika, Laura M Epure, Tomoaki Yoshikawa, Aseem Hemmad, Peter J Roughley, John Antoniou Arthritis Research & Therapy 2011, 13:R120 (25 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Atypical clinical presentation of a subset of patients with anti-RNA polymerase III - non-scleroderma cases associated with dominant RNA polymerase I reactivity and nucleolar staining

Angela Ceribelli, Malgorzata E Krzyszczak, Yi Li, Steven J Ross, Jason YF Chan, Edward KL Chan, Rufus W Burlingame, Tyler T Webb, Michael R Bubb, Eric S Sobel, Westley H Reeves, Minoru Satoh Arthritis Research & Therapy 2011, 13:R119 (22 July 2011)

Abstract | Full text | PDF | PubMed

Editorial   Free

Idiopathic aortitis: an underrecognized vasculitis

Nicolò Pipitone, Carlo Salvarani Arthritis Research & Therapy 2011, 13:119 (22 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Single-step autoantibody profiling in antiphospholipid syndrome using a multi-line dot assay

Karl Egerer, Dirk Roggenbuck, Thomas Büttner, Barbara Lehmann, Annushka Kohn, Philipp von Landenberg, Rico Hiemann, Eugen Feist, Gerd-Rüdiger Burmester, Thomas Dörner Arthritis Research & Therapy 2011, 13:R118 (21 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Influence of atorvastatin on coronary calcifications and myocardial perfusion defects in systemic lupus erythematosus patients: a prospective, randomized, double-masked, placebo-controlled study

Wojciech Plazak, Krzysztof Gryga, Hanna Dziedzic, Lidia Tomkiewicz-Pajak, Malgorzata Konieczynska, Piotr Podolec, Jacek Musial Arthritis Research & Therapy 2011, 13:R117 (20 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Association of acid phosphatase locus 1*C allele with the risk of cardiovascular events in rheumatoid arthritis patients

María Teruel, Jose-Ezequiel Martin, Carlos González-Juanatey, Raquel López-Mejias, Jose A Miranda-Filloy, Ricardo Blanco, Alejandro Balsa, Dora Pascual-Salcedo, Luis Rodriguez-Rodriguez, Benjamin Fernández-Gutierrez, Ana M Ortiz, Isidoro González-Alvaro, Carmen Gómez-Vaquero, Nunzio Bottini, Javier Llorca, Miguel A González-Gay, Javier Martin Arthritis Research & Therapy 2011, 13:R116 (18 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access Highly Accessed

The Bruton tyrosine kinase inhibitor PCI-32765 ameliorates autoimmune arthritis by inhibition of multiple effector cells

Betty Y Chang, Min Huang, Michelle Francesco, Jun Chen, Jeremy Sokolove, Padmaja Magadala, William H Robinson, Joseph J Buggy Arthritis Research & Therapy 2011, 13:R115 (13 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Free

The lung as a possible target for the immune reaction in myositis

Sonye K Danoff, Livia Casciola-Rosen Arthritis Research & Therapy 2011, 13:230 (13 July 2011)

Abstract | Full text | PDF | PubMed

Review   Free Highly Accessed

MicroRNAs in systemic rheumatic diseases

Angela Ceribelli, Bing Yao, Paul R Dominguez-Gutierrez, Md A Nahid, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2011, 13:229 (13 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

Characterization of a novel and spontaneous mouse model of inflammatory arthritis

Iris A Adipue, Joel T Wilcox, Cody King, Carolyn AY Rice, Katherine M Shaum, Cory M Suard, Elri Brink, Stephen D Miller, Eileen J McMahon Arthritis Research & Therapy 2011, 13:R114 (12 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Research article   Open Access

The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1

Yu-Jung Heo, Hye-Jwa Oh, Young Jung, Mi-La Cho, Seon-Yeong Lee, Jun-Geol Yu, Mi-Kyung Park, Hae-Rim Kim, Sang-Heon Lee, Sung-Hwan Park, Ho-Youn Kim Arthritis Research & Therapy 2011, 13:R113 (12 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Rates of, and risk factors for, severe infections in patients with systemic autoimmune diseases receiving biological agents off-label

Cándido Díaz-Lagares, Roberto Pérez-Alvarez, Francisco J García-Hernández, María M Ayala-Gutiérrez, José Callejas, Agustín Martínez-Berriotxoa, Javier Rascón, Luis Caminal-Montero, Albert Selva-O'Callaghan, Joaquim Oristrell, Carmen Hidalgo, Ricardo Gómez-de-la-Torre, Luis Sáez, Jesús Canora-Lebrato, María-Teresa Camps, Norberto Ortego-Centeno, María-Jesús Castillo-Palma, Manuel Ramos-Casals, the BIOGEAS Study Group Arthritis Research & Therapy 2011, 13:R112 (11 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Transforming growth factor β 869C/T and interleukin 6 -174G/C polymorphisms relate to the severity and progression of bone-erosive damage detected by ultrasound in rheumatoid arthritis

Fulvia Ceccarelli, Carlo Perricone, Martina Fabris, Cristiano Alessandri, Annamaria Iagnocco, Cinzia Fabro, Elena Pontarini, Salvatore De Vita, Guido Valesini Arthritis Research & Therapy 2011, 13:R111 (8 July 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Evaluation of long-term antinociceptive properties of stabilized hyaluronic acid preparation (NASHA) in an animal model of repetitive joint pain

Michael Boettger, Diana Kümmel, Andrew Harrison, Hans-Georg Schaible Arthritis Research & Therapy 2011, 13:R110 (7 July 2011)

Abstract | Full text | PDF | PubMed

Review   Free Highly Accessed

Cytokine disturbances in systemic lupus erythematosus

Noam Jacob, William Stohl Arthritis Research & Therapy 2011, 13:228 (6 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Review   Free

Disturbance of cytokine networks in Sjögren's syndrome

Pierre Youinou, Jacques-Olivier Pers Arthritis Research & Therapy 2011, 13:227 (6 July 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Commentary   Free

Neutrophils and interferon-α-producing cells: who produces interferon in lupus?

Patrice Decker Arthritis Research & Therapy 2011, 13:118 (6 July 2011)

Abstract | Full text | PDF | PubMed

Review   Free

Liver involvement in subjects with rheumatic disease

Carlo Selmi, Maria De Santis, M Eric Gershwin Arthritis Research & Therapy 2011, 13:226 (30 June 2011)

Abstract | Full text | PDF | PubMed

Review   Free

Cardiovascular co-morbidity in patients with rheumatic diseases

Johan Frostegård Arthritis Research & Therapy 2011, 13:225 (30 June 2011)

Abstract | Full text | PDF | PubMed

Review   Free

Conditions in subjects with rheumatic diseases: pulmonary manifestations of vasculitides

Julia U Holle, Frank Moosig, Klaus Dalhoff, Wolfgang L Gross Arthritis Research & Therapy 2011, 13:224 (30 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Free Highly Accessed

Fibromyalgia, myofascial pain, tender points and trigger points: splitting or lumping?

Robert M Bennett, Don L Goldenberg Arthritis Research & Therapy 2011, 13:117 (30 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Promoter polymorphisms in the chitinase 3-like 1 gene influence the serum concentration of YKL-40 in Danish patients with rheumatoid arthritis and in healthy subjects

Kaspar R Nielsen, Rudi Steffensen, Martin Boegsted, John Baech, Soeren Lundbye-Christensen, Merete L Hetland, Sophine B Krintel, Hans E Johnsen, Mette Nyegaard, Julia S Johansen Arthritis Research & Therapy 2011, 13:R109 (29 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access Highly Accessed

Disease activity and low physical activity associate with number of hospital admissions and length of hospitalisation in patients with rheumatoid arthritis

George S Metsios, Antonios Stavropoulos-Kalinoglou, Gareth J Treharne, Alan M Nevill, Aamer Sandoo, Vasileios F Panoulas, Tracey E Toms, Yiannis Koutedakis, George D Kitas Arthritis Research & Therapy 2011, 13:R108 (29 June 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Physical activity and disease activity are important predictors of hospital admissions and length of hospitalisation in rheumatoid arthritis patients, suggesting lifestyle changes combined with effective pharmacological therapy may improve health and economic outcomes.

Review   Free Highly Accessed

Treating rheumatic patients with a malignancy

Katarzyna Elandt, Daniel Aletaha Arthritis Research & Therapy 2011, 13:223 (29 June 2011)

Abstract | Full text | PDF | PubMed

Review   Free

Renal co-morbidity in patients with rheumatic diseases

Hans-Joachim Anders, Volker Vielhauer Arthritis Research & Therapy 2011, 13:222 (29 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

Editorial   Free

Considering comorbidity in managing rheumatic diseases: going where trials cannot go

Daniel Aletaha, Thomas Dörner Arthritis Research & Therapy 2011, 13:116 (29 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Identification of target antigens of anti-endothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach

Alexis Régent, Hanadi Dib, Kim H Ly, Christian Agard, Mathieu C Tamby, Nicolas Tamas, Babette Weksler, Christian Federici, Cédric Broussard, Loïc Guillevin, Luc Mouthon Arthritis Research & Therapy 2011, 13:R107 (28 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Defective response of CD4+ T cells to retinoic acid and TGFβ in systemic lupus erythematosus

Eric S Sobel, Todd M Brusko, Ed J Butfiloski, Wei Hou, Shiwu Li, Carla M Cuda, Ariana N Abid, Westley H Reeves, Laurence Morel Arthritis Research & Therapy 2011, 13:R106 (27 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Antibodies toward infliximab are associated with low infliximab concentration at treatment initiation and poor infliximab maintenance in rheumatic diseases

Emilie Ducourau, Denis Mulleman, Gilles Paintaud, Delphine Miow Lin, Francine Lauféron, David Ternant, Hervé Watier, Philippe Goupille Arthritis Research & Therapy 2011, 13:R105 (27 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

High initial serum concentration of infliximab reduces the development of antibodies towards infliximab (ATI) and absence of ATI may be associated with prolonged maintenance of infliximab, suggesting infliximab serum concentrations should be monitored early.

Research article   Open Access

Potential role and mechanism of IFN-gamma inducible protein-10 on receptor activator of nuclear factor kappa-B ligand (RANKL) expression in rheumatoid arthritis

Eun Lee, MiRan Seo, Yong-Sung Juhnn, Jeong Kim, Yoo Hong, Yun Lee, Eun Lee, Yeong Song Arthritis Research & Therapy 2011, 13:R104 (27 June 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Arthritis is associated with T-cell-induced upregulation of Toll-like receptor 3 on synovial fibroblasts

Wenhua Zhu, Liesu Meng, Congshan Jiang, Xiaojing He, Weikun Hou, Peng Xu, Heng Du, Rikard Holmdahl, Shemin Lu Arthritis Research & Therapy 2011, 13:R103 (27 June 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

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