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Recent advances in shoulder research
Megan L Killian, Leonardo Cavinatto, Leesa M Galatz, Stavros Thomopoulos Arthritis Research & Therapy 2012, 14:214 (15 June 2012)
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Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus
Zahava Vadasz, Tharwat Haj, Katalin Halasz, Itzhak Rosner, Gleb Slobodin, Dina Attias, Aharon Kessel, Ofra Kessler, Gera Neufeld, Elias Toubi Arthritis Research & Therapy 2012, 14:R146 (14 June 2012)
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B-cell depletion therapy in patients with diffuse systemic sclerosis associates with a significant decrease in PDGFR expression and activation in spindle-like cells in the skin
Dimitrios Daoussis, Athanassios C Tsamandas, Stamatis-Nick C Liossis, Ioannis Antonopoulos, Elli Karatza, Georgios Yiannopoulos, Andrew P Andonopoulos Arthritis Research & Therapy 2012, 14:R145 (14 June 2012)
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CD109, a TGF-β co-receptor, attenuates extracellular matrix production in scleroderma skin fibroblasts
Xiao-Yong Man, Kenneth W Finnson, Murray Baron, Anie Philip Arthritis Research & Therapy 2012, 14:R144 (13 June 2012)
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N-terminal pro-brain natriuretic peptide in a novel screening algorithm for pulmonary arterial hypertension in systemic sclerosis: a case-control study
Vivek Thakkar, Wendy M Stevens, David Prior, Owen A Moore, Jillian Byron, Danny Liew, Karen Patterson, Pravin Hissaria, Janet Roddy, Jane Zochling, Joanne Sahhar, Peter Nash, Kathleen Tymms, David Celermajer, Eli Gabbay, Peter Youssef, Susanna M Proudman, Mandana Nikpour Arthritis Research & Therapy 2012, 14:R143 (12 June 2012)
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Investigation of the role of endosomal Toll-like receptors in murine collagen-induced arthritis reveals a potential role for TLR7 in disease maintenance
Saba Alzabin, Philip Kong, Mino Medghalchi, Andrew Palfreeman, Richard Williams, Sandra Sacre Arthritis Research & Therapy 2012, 14:R142 (12 June 2012)
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Anti-tumor necrosis factor therapy improves insulin resistance, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance
Ilias Stagakis, George Bertsias, Stylianos Karvounaris, Melina Kavousanaki, Dimitra Virla, Amalia Raptopoulou, Dimitrios Kardassis, Dimitrios T Boumpas, Prodromos I Sidiropoulos Arthritis Research & Therapy 2012, 14:R141 (12 June 2012)
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Editor’s summary
Twelve weeks of anti-tumor necrosis factor (TNF) therapy improved insulin sensitivity, beta cell function and insulin signaling in active rheumatoid arthritis patients with high insulin resistance.
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C5a and its receptors in human anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis
Jun Yuan, Shen-Ju Gou, Jing Huang, Jian Hao, Min Chen, Ming-Hui Zhao Arthritis Research & Therapy 2012, 14:R140 (12 June 2012)
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Osteoblastogenesis from synovial fluid-derived cells is related to the type and severity of juvenile idiopathic arthritis
Elvira Lazić, Marija Jelušić, Danka Grčević, Ana Marušić, Nataša Kovačić Arthritis Research & Therapy 2012, 14:R139 (12 June 2012)
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Adenosine receptor expression in rheumatoid synovium: a basis for methotrexate action
Lisa K Stamp, Jody Hazlett, Rebecca L Roberts, Christopher Frampton, John Highton, Paul A Hessian Arthritis Research & Therapy 2012, 14:R138 (8 June 2012)
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Recent advances in the diagnosis and treatment of hemophagocytic lymphohistiocytosis
Sebastian FN Bode, Kai Lehmberg, Andrea Maul-Pavicic, Thomas Vraetz, Gritta Janka, Udo Stadt, Stephan Ehl Arthritis Research & Therapy 2012, 14:213 (8 June 2012)
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Interleukin-7-aggravated joint inflammation and tissue destruction in collagen-induced arthritis is associated with T-cell and B-cell activation
Sarita AY Hartgring, Cynthia R Willis, Johannes WJ Bijlsma, Floris PJG Lafeber, Joel AG van Roon Arthritis Research & Therapy 2012, 14:R137 (7 June 2012)
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Properties and usefulness of aggregates of synovial mesenchymal stem cells as a source for cartilage regeneration
Shiro Suzuki, Takeshi Muneta, Kunikazu Tsuji, Shizuko Ichinose, Hatsune Makino, Akihiro Umezawa, Ichiro Sekiya Arthritis Research & Therapy 2012, 14:R136 (7 June 2012)
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Editor’s summary
Aggregated mesenchymal stem cells are a useful source for cartilage regeneration, as they are easy to prepare, have high chondrogenic potential and attach efficiently.
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Hydroxychloroquine improves insulin sensitivity in obese non-diabetic individuals
Emileigh Mercer, Laura Rekedal, Rajesh Garg, Bing Lu, Elena M Massarotti, Daniel H Solomon Arthritis Research & Therapy 2012, 14:R135 (7 June 2012)
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Establishment and characterization of a sustained delayed-type hypersensitivity model with arthritic manifestations in C57BL/6J mice
Sara M Atkinson, Pernille A Usher, Peter H Kvist, Helle Markholst, Claus Haase, Anneline Nansen Arthritis Research & Therapy 2012, 14:R134 (7 June 2012)
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Editor’s summary
The delayed-type hypersensitivity arthritis model shares features with human rheumatoid arthritis and the collagen-induced arthritis model, and may have potential for the preclinical screening of novel drugs against rheumatoid arthritis.
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Early diagnosis to enable early treatment of pre-osteoarthritis
Constance R Chu, Ashley A Williams, Christian H Coyle, Megan E Bowers Arthritis Research & Therapy 2012, 14:212 (7 June 2012)
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The interaction of canonical bone morphogenetic protein- and Wnt-signaling pathways may play an important role in regulating cartilage degradation in osteoarthritis
Benjamin Y Chan, Christopher B Little Arthritis Research & Therapy 2012, 14:119 (6 June 2012)
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Upregulation of tumor necrosis factor receptor-associated factor 6 correlated with synovitis severity in rheumatoid arthritis
Lang-Jing Zhu, Lie Dai, Dong-Hui Zheng, Ying-Qian Mo, Xia Ou-Yang, Xiu-Ning Wei, Jun Shen, Bai-Yu Zhang Arthritis Research & Therapy 2012, 14:R133 (4 June 2012)
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The relationship between hand osteoarthritis and serum leptin concentration in participants of the Third National Health and Nutrition Examination Survey
Mei Massengale, William M Reichmann, Elena Losina, Daniel H Solomon, Jeffrey N Katz Arthritis Research & Therapy 2012, 14:R132 (31 May 2012)
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Evaluating joint-space narrowing and cartilage loss in rheumatoid arthritis by using MRI
Charles G Peterfy, Julie C DiCarlo, Ewa Olech, Maire-Agnes Bagnard, Annarita Gabriele, Norman Gaylis Arthritis Research & Therapy 2012, 14:R131 (30 May 2012)
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Treatment with the arginase inhibitor Nw-hydroxy-nor-L-arginine restores endothelial function in rat adjuvant-induced arthritis
Clément Prati, Alain Berthelot, Bernadette Kantelip, Daniel Wendling, Céline Demougeot Arthritis Research & Therapy 2012, 14:R130 (30 May 2012)
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Defining cut-off values for disease activity states and improvement scores for patient-reported outcomes: the example of the Rheumatoid Arthritis Impact of Disease (RAID)
Maxime Dougados, Yves Brault, Isabelle Logeart, Désirée van der Heijde, Laure Gossec, Tore Kvien Arthritis Research & Therapy 2012, 14:R129 (30 May 2012)
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A new immunoprecipitation-real time quantitative PCR assay for anti-Th/To and anti-U3RNP antibody detection in systemic sclerosis
Angela Ceribelli, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2012, 14:R128 (29 May 2012)
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The genetics of lupus: a functional perspective
Sandra G Guerra, Timothy J Vyse, Deborah S Cunninghame Graham Arthritis Research & Therapy 2012, 14:211 (29 May 2012)
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Association of cytokine and matrix metalloproteinase profiles with disease activity and function in ankylosing spondylitis
Derek L Mattey, Jonathan C Packham, Nicola B Nixon, Lucy Coates, Paul Creamer, Sarah Hailwood, Gordon J Taylor, Ashok K Bhalla Arthritis Research & Therapy 2012, 14:R127 (28 May 2012)
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