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Mesenchymal stem cells in autoimmune diseases: hype or hope?
Hans U Scherer, Melissa van Pel, René EM Toes Arthritis Research & Therapy 2010, 12:126 (18 June 2010)
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Vascular alterations upon activation of TGFβ signaling in fibroblasts - implications for systemic sclerosis
Angelika Horn, Jörg HW Distler Arthritis Research & Therapy 2010, 12:125 (18 June 2010)
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Preventive health services for systemic lupus erythematosus patients: whose job is it?
Paula I Burgos, Graciela S Alarcón Arthritis Research & Therapy 2010, 12:124 (17 June 2010)
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Interleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritis
Jeffrey H Ruth, Christy C Park, M Asif Amin, Charles Lesch, Hubert Marotte, Shiva Shahrara, Alisa E Koch Arthritis Research & Therapy 2010, 12:R118 (16 June 2010)
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Effectiveness and safety of adalimumab in patients with ankylosing spondylitis or psoriatic arthritis and history of anti-tumor necrosis factor therapy
Martin Rudwaleit, Filip Van den Bosch, Martina Kron, Sonja Kary, Hartmut Kupper Arthritis Research & Therapy 2010, 12:R117 (16 June 2010)
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Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance
Jade E Hollis-Moffatt, Michael Chen-Xu, Ruth Topless, Nicola Dalbeth, Peter J Gow, Andrew A Harrison, John Highton, Peter BB Jones, Michael Nissen, Malcolm D Smith, Andre van Rij, Gregory T Jones, Lisa K Stamp, Tony R Merriman Arthritis Research & Therapy 2010, 12:R116 (16 June 2010)
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Peptidyl arginine deiminase type IV (PADI4) haplotypes interact with shared epitope regardless of anti-cyclic citrullinated peptide antibody or erosive joint status in rheumatoid arthritis: a case control study
So-Young Bang, Tae-Un Han, Chan-Bum Choi, Yoon-Kyoung Sung, Sang-Cheol Bae, Changwon Kang Arthritis Research & Therapy 2010, 12:R115 (10 June 2010)
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Editor’s summary
Genetic polymorphisms in a citrullinating enzyme were significantly associated with susceptibility to rheumatoid arthritis regardless of anti-cyclic citrullinated peptide autoantibodies and disease severity (erosive joint status).
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Cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection
Marijn Rutgers, Daniël BF Saris, Wouter JA Dhert, Laura B Creemers Arthritis Research & Therapy 2010, 12:R114 (10 June 2010)
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Risk factors for radiographic progression in psoriatic arthritis: subanalysis of the randomized controlled trial ADEPT
Dafna D Gladman, Philip J Mease, Ernest HS Choy, Christopher T Ritchlin, Renee J Perdok, Eric H Sasso Arthritis Research & Therapy 2010, 12:R113 (10 June 2010)
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Obesity affects the chondrocyte responsiveness to leptin in patients with osteoarthritis
Stéphane Pallu, Pierre-Jean Francin, Cécile Guillaume, Pascale Gegout-Pottie, Patrick Netter, Didier Mainard, Bernard Terlain, Nathalie Presle Arthritis Research & Therapy 2010, 12:R112 (9 June 2010)
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Vaccination response to protein and carbohydrate antigens in patients with rheumatoid arthritis after rituximab treatment
Maria Rehnberg, Mikael Brisslert, Sylvie Amu, Kiandoht Zendjanchi, Gunilla Håwi, Maria I Bokarewa Arthritis Research & Therapy 2010, 12:R111 (8 June 2010)
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The role of stress in rheumatic diseases
Afton L Hassett, Daniel J Clauw Arthritis Research & Therapy 2010, 12:123 (7 June 2010)
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Tumor necrosis factor and norepinephrine lower the levels of human neutrophil peptides 1-3 secretion by mixed synovial tissue cultures in osteoarthritis and rheumatoid arthritis
Birgit Riepl, Susanne Grässel, Reiner Wiest, Martin Fleck, Rainer H Straub Arthritis Research & Therapy 2010, 12:R110 (4 June 2010)
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Phenotype and functional changes of Vγ9/Vδ2 T lymphocytes in Behçet's disease and the effect of infliximab on Vγ9/Vδ2 T cell expansion, activation and cytotoxicity
Antonina Accardo-Palumbo, Anna Rita Giardina, Francesco Ciccia, Angelo Ferrante, Alfonso Principato, Rosalia Impastato, Ennio Giardina, Giovanni Triolo Arthritis Research & Therapy 2010, 12:R109 (3 June 2010)
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Arthritis: where are the T cells?
Thomas Kamradt, Oliver Frey Arthritis Research & Therapy 2010, 12:122 (3 June 2010)
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Informed consent: time for more transparency
Yusuf Yazici, Hasan Yazici Arthritis Research & Therapy 2010, 12:121 (3 June 2010)
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Decreased frequency and activated phenotype of blood CD27 IgD IgM B lymphocytes is a permanent abnormality in systemic lupus erythematosus patients
Beatriz Rodríguez-Bayona, Ana Ramos-Amaya, José J Pérez-Venegas, Carmen Rodríguez, José A Brieva Arthritis Research & Therapy 2010, 12:R108 (2 June 2010)
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Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis
Fiona E McCann, Andrew C Palfreeman, Melanie Andrews, Dany P Perocheau, Julia J Inglis, Peter Schafer, Marc Feldmann, Richard O Williams, Fionula M Brennan Arthritis Research & Therapy 2010, 12:R107 (2 June 2010)
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Bacterial and human peptidylarginine deiminases: targets for inhibiting the autoimmune response in rheumatoid arthritis?
Pamela Mangat, Natalia Wegner, Patrick J Venables, Jan Potempa Arthritis Research & Therapy 2010, 12:209 (2 June 2010)
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Mechanical signals control SOX-9, VEGF, and c-Myc expression and cell proliferation during inflammation via integrin-linked kinase, B-Raf, and ERK1/2-dependent signaling in articular chondrocytes
Priyangi M Perera, Ewa Wypasek, Shashi Madhavan, Birgit Rath-Deschner, Jie Liu, Jin Nam, Bjoern Rath, Yan Huang, James Deschner, Nicholas Piesco, Chuanyue Wu, Sudha Agarwal Arthritis Research & Therapy 2010, 12:R106 (28 May 2010)
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Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis
Jeffrey D Peterson, Timothy P LaBranche, Kristine O Vasquez, Sylvie Kossodo, Michele Melton, Randall Rader, John T Listello, Mark A Abrams, Thomas P Misko Arthritis Research & Therapy 2010, 12:R105 (28 May 2010)
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Editor’s summary
Non-invasive optical tomographic imaging assessment in collagen antibody-induced arthritis can discriminate disease-modifying anti-rheumatic drug (DMARD) from non-DMARD activity, offering a unique approach to monitoring disease pathogenesis.
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Do we need new autoantibodies in lupus?
R Hal Scofield Arthritis Research & Therapy 2010, 12:120 (28 May 2010)
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Respiratory symptoms and disease characteristics as predictors of pulmonary function abnormalities in patients with rheumatoid arthritis: an observational cohort study
Dimitrios A Pappas, Jon T Giles, Geoffrey Connors, Noah Lechtzin, Joan M Bathon, Sonye K Danoff Arthritis Research & Therapy 2010, 12:R104 (27 May 2010)
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If good things come from above, do bad things come from below?
David M Findlay Arthritis Research & Therapy 2010, 12:119 (27 May 2010)
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Toll-like receptor 3 upregulation in macrophages participates in the initiation and maintenance of pristane-induced arthritis in rats
Liesu Meng, Wenhua Zhu, Congshan Jiang, Xiaojing He, Weikun Hou, Fang Zheng, Rikard Holmdahl, Shemin Lu Arthritis Research & Therapy 2010, 12:R103 (25 May 2010)
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Association between occupation and knee and hip replacement due to osteoarthritis: a case-control study
Jonas Franklin, Thorvaldur Ingvarsson, Martin Englund, Stefan Lohmander Arthritis Research & Therapy 2010, 12:R102 (24 May 2010)
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Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor α but not estrogen receptor β
John Dulos, Peter Vijn, Cindy van Doorn, Claudia L Hofstra, Desiree Veening-Griffioen, Jan de Graaf, Fred A Dijcks, Annemieke MH Boots Arthritis Research & Therapy 2010, 12:R101 (24 May 2010)
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Correction: DNA microarray analysis of rheumatoid arthritis susceptibility genes identified by genome-wide association studies
Hidehiko Sugino, Hooi-Ming Lee, Norihiro Nishimoto Arthritis Research & Therapy 2010, 12:403 (24 May 2010)
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The enigma that is the nucleus pulposus cell: the search goes on
W Mark Erwin Arthritis Research & Therapy 2010, 12:118 (24 May 2010)
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Physiological tonicity improves human chondrogenic marker expression through nuclear factor of activated T-cells 5 in vitro
Anna E van der Windt, Esther Haak, Ruud HJ Das, Nicole Kops, Tim JM Welting, Marjolein MJ Caron, Niek P van Til, Jan AN Verhaar, Harrie Weinans, Holger Jahr Arthritis Research & Therapy 2010, 12:R100 (21 May 2010)
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Clinical and serological evaluation of a novel CENP-A peptide based ELISA
Michael Mahler, Liesbeth Maes, Daniel Blockmans, Rene Westhovens, Xavier Bossuyt, Gabriela Riemekasten, Sandra Schneider, Falk Hiepe, Andreas Swart, Irmgard Gürtler, Karl Egerer, Margrit Fooke, Marvin J Fritzler Arthritis Research & Therapy 2010, 12:R99 (20 May 2010)
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The value of ultrasonography in predicting arthritis in auto-antibody positive arthralgia patients: a prospective cohort study
Lotte A van de Stadt, Wouter H Bos, Marlies Meursinge Reynders, Helen Wieringa, Franktien Turkstra, Conny J van der Laken, Dirkjan van Schaardenburg Arthritis Research & Therapy 2010, 12:R98 (20 May 2010)
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Time to achieve remission determines time to be in remission
Lydia G Schipper, Jaap Fransen, Alfons A den Broeder, Piet LCM Van Riel Arthritis Research & Therapy 2010, 12:R97 (20 May 2010)
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Accelerated hand bone mineral density loss is associated with progressive joint damage in hands and feet in recent-onset rheumatoid arthritis
Melek Güler-Yüksel, Naomi B Klarenbeek, Yvonne PM Goekoop-Ruiterman, Jeska K de Vries-Bouwstra, Sjoerd M van der Kooij, Andreas H Gerards, H Karel Ronday, Tom WJ Huizinga, Ben AC Dijkmans, Cornelia F Allaart, Willem F Lems Arthritis Research & Therapy 2010, 12:R96 (20 May 2010)
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Transcriptional profiling of the nucleus pulposus: say yes to notochord
Irving M Shapiro, Makarand V Risbud Arthritis Research & Therapy 2010, 12:117 (20 May 2010)
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The meniscus, calcification and osteoarthritis: a pathologic team
Paul A MacMullan, Geraldine M McCarthy Arthritis Research & Therapy 2010, 12:116 (20 May 2010)
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The association between leptin, interleukin-6, and hip radiographic osteoarthritis in older people: a cross-sectional study
Oliver P Stannus, Graeme Jones, Stephen J Quinn, Flavia M Cicuttini, Dawn Dore, Changhai Ding Arthritis Research & Therapy 2010, 12:R95 (19 May 2010)
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Remission in psoriatic arthritis: is it possible and how can it be predicted?
Tajvur P Saber, CT Ng, Guillaume Renard, Bernadette M Lynch, Eliza Pontifex, Ceara AE Walsh, Alexia Grier, Marian Molloy, Barry Bresnihan, Oliver FitzGerald, Ursula Fearon, Douglas J Veale Arthritis Research & Therapy 2010, 12:R94 (18 May 2010)
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Treatment with apolipoprotein A-1 mimetic peptide reduces lupus-like manifestations in a murine lupus model of accelerated atherosclerosis
Jennifer MP Woo, Zhuofeng Lin, Mohamad Navab, Casey Van Dyck, Yvette Trejo-Lopez, Krystal MT Woo, Hongyun Li, Lawrence W Castellani, Xuping Wang, Noriko Iikuni, Ornella J Rullo, Hui Wu, Antonio La Cava, Alan M Fogelman, Aldons J Lusis, Betty P Tsao Arthritis Research & Therapy 2010, 12:R93 (18 May 2010)
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Inhibitory effects of ZSTK474, a novel phosphoinositide 3-kinase inhibitor, on osteoclasts and collagen-induced arthritis in mice
Shoko Toyama, Naoto Tamura, Kazuhiko Haruta, Takeo Karakida, Shigeyuki Mori, Tetsuo Watanabe, Takao Yamori, Yoshinari Takasaki Arthritis Research & Therapy 2010, 12:R92 (18 May 2010)
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Phenotypic and functional abnormalities of bone marrow-derived dendritic cells in systemic lupus erythematosus
Ying J Nie, Mo Y Mok, Godfrey CF Chan, Albert W Chan, Ou Jin, Sushma Kavikondala, Albert KW Lie, Chak S Lau Arthritis Research & Therapy 2010, 12:R91 (18 May 2010)
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Monocyte surface expression of Fcγ receptor RI (CD64), a biomarker reflecting type-I interferon levels in systemic lupus erythematosus
Yi Li, Pui Y Lee, Erinn S Kellner, Matthew Paulus, Juliana Switanek, Yuan Xu, Haoyang Zhuang, Eric S Sobel, Mark S Segal, Minoru Satoh, Westley H Reeves Arthritis Research & Therapy 2010, 12:R90 (18 May 2010)
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Experimental stress in inflammatory rheumatic diseases: a review of psychophysiological stress responses
Sabine JM de Brouwer, Floris W Kraaimaat, Fred CGJ Sweep, Marjonne CW Creemers, Timothy RDJ Radstake, Antoinette IM van Laarhoven, Piet LCM van Riel, Andrea WM Evers Arthritis Research & Therapy 2010, 12:R89 (17 May 2010)
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Individual and occupational risk factors for knee osteoarthritis: results of a case-control study in Germany
André Klussmann, Hansjürgen Gebhardt, Matthias Nübling, Falk Liebers, Emilio Quirós Perea, Wolfgang Cordier, Lars V von Engelhardt, Markus Schubert, Andreas Dávid, Bertil Bouillon, Monika A Rieger Arthritis Research & Therapy 2010, 12:R88 (14 May 2010)
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Inhibitor of IκB kinase activity, BAY 11-7082, interferes with interferon regulatory factor 7 nuclear translocation and type I interferon production by plasmacytoid dendritic cells
Rie Miyamoto, Tomoki Ito, Shosaku Nomura, Ryuichi Amakawa, Hideki Amuro, Yuichi Katashiba, Makoto Ogata, Naoko Murakami, Keiko Shimamoto, Chihiro Yamazaki, Katsuaki Hoshino, Tsuneyasu Kaisho, Shirou Fukuhara Arthritis Research & Therapy 2010, 12:R87 (14 May 2010)
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Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis
Koichi Murata, Hiroyuki Yoshitomi, Shimei Tanida, Masahiro Ishikawa, Kohei Nishitani, Hiromu Ito, Takashi Nakamura Arthritis Research & Therapy 2010, 12:R86 (14 May 2010)
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Autoantibodies to angiotensin-converting enzyme 2 in patients with connective tissue diseases
Yuko Takahashi, Shiori Haga, Yukihito Ishizaka, Akio Mimori Arthritis Research & Therapy 2010, 12:R85 (14 May 2010)
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Provision of preventive health care in systemic lupus erythematosus: data from a large observational cohort study
Jinoos Yazdany, Chris Tonner, Laura Trupin, Pantelis Panopalis, Joann Z Gillis, Aimee O Hersh, Laura J Julian, Patricia P Katz, Lindsey A Criswell, Edward H Yelin Arthritis Research & Therapy 2010, 12:R84 (12 May 2010)
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Cell culture and passaging alters gene expression pattern and proliferation rate in rheumatoid arthritis synovial fibroblasts
Elena Neumann, Birgit Riepl, Anette Knedla, Stephanie Lefèvre, Ingo H Tarner, Joachim Grifka, Jurgen Steinmeyer, Jurgen Schölmerich, Steffen Gay, Ulf Müller-Ladner Arthritis Research & Therapy 2010, 12:R83 (12 May 2010)
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Biomechanical modulation of collagen fragment-induced anabolic and catabolic activities in chondrocyte/agarose constructs
Tina T Chowdhury, Ronny M Schulz, Sonpreet S Rai, Christian B Thuemmler, Nico Wuestneck, Augustinus Bader, Gene A Homandberg Arthritis Research & Therapy 2010, 12:R82 (12 May 2010)
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Correction: Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus
Kamini Shah, Won-Woo Lee, Seung-Hyun Lee, Sang Kim, Seong Kang, Joe Craft, Insoo Kang Arthritis Research & Therapy 2010, 12:402 (12 May 2010)
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Altered microRNA expression profile with miR-146a upregulation in CD4+ T cells from patients with rheumatoid arthritis
Jingyi Li, Ying Wan, Qiuye Guo, Liyun Zou, Jinyu Zhang, Yongfei Fang, Jingbo Zhang, Jinjun Zhang, Xiaolan Fu, Hongli Liu, Liwei Lu, Yuzhang Wu Arthritis Research & Therapy 2010, 12:R81 (11 May 2010)
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Natural killer cells control a T-helper 1 response in patients with Behçet's disease
Yukie Yamaguchi, Hayato Takahashi, Takashi Satoh, Yuka Okazaki, Nobuhisa Mizuki, Kazuo Takahashi, Zenro Ikezawa, Masataka Kuwana Arthritis Research & Therapy 2010, 12:R80 (11 May 2010)
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Efficacy of different types of aerobic exercise in fibromyalgia syndrome: a systematic review and meta-analysis of randomised controlled trials
Winfried Häuser, Petra Klose, Jost Langhorst, Babak Moradi, Mario Steinbach, Marcus Schiltenwolf, Angela Busch Arthritis Research & Therapy 2010, 12:R79 (10 May 2010)
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Endothelial cell markers reflecting endothelial cell dysfunction in patients with mixed connective tissue disease
Pal Soltesz, Daniel Bereczki, Peter Szodoray, Maria T Magyar, Henrietta Der, Istvan Csipo, Agota Hajas, Gyorgy Paragh, Gyula Szegedi, Edit Bodolay Arthritis Research & Therapy 2010, 12:R78 (6 May 2010)
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Seven-year follow-up of infliximab therapy in rheumatoid arthritis patients with severe long-standing refractory disease: attrition rate and evolution of disease activity
Bert Vander Cruyssen, Patrick Durez, Rene Westhovens, Filip De Keyser Arthritis Research & Therapy 2010, 12:R77 (6 May 2010)
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The likelihood of persistent arthritis increases with the level of anti-citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376 patients with very early undifferentiated arthritis
Maria D Mjaavatten, Désirée Heijde, Till Uhlig, Anne J Haugen, Halvor Nygaard, Göran Sidenvall, Knut Helgetveit, Tore K Kvien Arthritis Research & Therapy 2010, 12:R76 (5 May 2010)
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Association of IL4R single-nucleotide polymorphisms with rheumatoid nodules in African Americans with rheumatoid arthritis
Paula I Burgos, Zenoria L Causey, Ashutosh Tamhane, James M Kelley, Elizabeth E Brown, Laura B Hughes, Maria I Danila, Amalia van Everdingen, Doyt L Conn, Beth L Jonas, Leigh F Callahan, Edwin A Smith, Richard D Brasington, Larry W Moreland, Désirée M van der Heijde, Graciela S Alarcón, S Louis Bridges Arthritis Research & Therapy 2010, 12:R75 (5 May 2010)
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Chronic nonbacterial osteomyelitis in childhood: prospective follow-up during the first year of anti-inflammatory treatment
Christine Beck, Henner Morbach, Meinrad Beer, Martin Stenzel, Dennis Tappe, Stefan Gattenlöhner, Ulrich Hofmann, Peter Raab, Hermann J Girschick Arthritis Research & Therapy 2010, 12:R74 (30 April 2010)
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Transcriptional regulation of matrix metalloproteinase-1 and collagen 1A2 explains the anti-fibrotic effect exerted by proteasome inhibition in human dermal fibroblasts
Laurence Goffin, Queralt Seguin-Estévez, Montserrat Alvarez, Walter Reith, Carlo Chizzolini Arthritis Research & Therapy 2010, 12:R73 (29 April 2010)
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Green tea polyphenol epigallocatechin 3-gallate in arthritis: progress and promise
Salahuddin Ahmed Arthritis Research & Therapy 2010, 12:208 (28 April 2010)
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Clinical effectiveness of biologics in clinical practice
David L Scott, Gabrielle Kingsley Arthritis Research & Therapy 2010, 12:115 (28 April 2010)
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Challenges and opportunities of publishing supplements at Arthritis Research & Therapy
Frances Mulvany, Jo Baker, Peter E Lipsky, Ravinder N Maini Arthritis Research & Therapy 2010, 12:113 (28 April 2010)
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Lack of replication of genetic predictors for the rheumatoid arthritis response to anti-TNF treatments: a prospective case-only study
Marian Suarez-Gestal, Eva Perez-Pampin, Manuel Calaza, Juan J Gomez-Reino, Antonio Gonzalez Arthritis Research & Therapy 2010, 12:R72 (27 April 2010)
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A1298C polymorphism in the MTHFR gene predisposes to cardiovascular risk in rheumatoid arthritis
Rogelio Palomino-Morales, Carlos Gonzalez-Juanatey, Tomas R Vazquez-Rodriguez, Luis Rodriguez, Jose A Miranda-Filloy, Benjamin Fernandez-Gutierrez, Javier Llorca, Javier Martin, Miguel A Gonzalez-Gay Arthritis Research & Therapy 2010, 12:R71 (26 April 2010)
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The role of dendritic cells in the pathogenesis of systemic lupus erythematosus
Justin H Fransen, Johan Vlag, Jurjen Ruben, Gosse J Adema, Jo H Berden, Luuk B Hilbrands Arthritis Research & Therapy 2010, 12:207 (26 April 2010)
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Gout. Mechanisms of inflammation in gout
Nathalie Busso, Alexander So Arthritis Research & Therapy 2010, 12:206 (26 April 2010)
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Which patients with rheumatoid arthritis are still working?
Till Uhlig Arthritis Research & Therapy 2010, 12:114 (26 April 2010)
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B-cell depletion with rituximab: a promising treatment for diffuse cutaneous systemic sclerosis
Jacob M van Laar Arthritis Research & Therapy 2010, 12:112 (22 April 2010)
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Systemic lupus erythematosus and its ABCs (APRIL/BLyS complexes)
William Stohl Arthritis Research & Therapy 2010, 12:111 (22 April 2010)
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Cancer risks of dermatomyositis and polymyositis: a nationwide cohort study in Taiwan
Yi-Ju Chen, Chun-Ying Wu, Yu-Lin Huang, Chang-Bi Wang, Jui-Lung Shen, Yun-Ting Chang Arthritis Research & Therapy 2010, 12:R70 (16 April 2010)
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Systemic vasculopathy with altered vasoreactivity in a transgenic mouse model of scleroderma
Emma C Derrett-Smith, Audrey Dooley, Korsa Khan, Xu Shi-wen, David Abraham, Christopher P Denton Arthritis Research & Therapy 2010, 12:R69 (15 April 2010)
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B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcγRIIb, which are modulated by anti-tumor necrosis factor therapy
Diego Catalán, Octavio Aravena, Francisca Sabugo, Pamela Wurmann, Lilian Soto, Alexis M Kalergis, Miguel Cuchacovich, Juan C Aguillón, Millenium Nucleus on Immunology and Immunotherapy P-07-088-F Arthritis Research & Therapy 2010, 12:R68 (15 April 2010)
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Infections requiring hospitalization in the abatacept clinical development program: an epidemiological assessment
Teresa A Simon, Johan Askling, Diane Lacaille, Jarrod Franklin, Frederick Wolfe, Allison Covucci, Samy Suissa, Marc C Hochberg, the Abatacept Epidemiology Study Group Arthritis Research & Therapy 2010, 12:R67 (14 April 2010)
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FoxP3 and Bcl-xL cooperatively promote regulatory T cell persistence and prevention of arthritis development
Rizwanul Haque, Fengyang Lei, Xiaofang Xiong, Yuzhang Wu, Jianxun Song Arthritis Research & Therapy 2010, 12:R66 (12 April 2010)
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New role for Agrin in T cells and its potential importance in immune system regulation
Elizabeth C Jury, Panagiotis S Kabouridis Arthritis Research & Therapy 2010, 12:205 (12 April 2010)
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Platelet-derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast-like synoviocytes
Sanna Rosengren, Maripat Corr, David L Boyle Arthritis Research & Therapy 2010, 12:R65 (9 April 2010)
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Brain perfusion in fibromyalgia patients and its differences between responders and poor responders to gabapentin
Chie Usui, Kotaro Hatta, Nagafumi Doi, Atsushi Nakanishi, Hiroyuki Nakamura, Kusuki Nishioka, Heii Arai Arthritis Research & Therapy 2010, 12:R64 (7 April 2010)
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The urate-lowering efficacy and safety of febuxostat in the treatment of the hyperuricemia of gout: the CONFIRMS trial
Michael A Becker, H Ralph Schumacher, Luis R Espinoza, Alvin F Wells, Patricia MacDonald, Eric Lloyd, Christopher Lademacher Arthritis Research & Therapy 2010, 12:R63 (6 April 2010)
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Influence of HLA DRB1 alleles in the susceptibility of rheumatoid arthritis and the regulation of antibodies against citrullinated proteins and rheumatoid factor
Alejandro Balsa, Arancha Cabezón, Gisela Orozco, Tatiana Cobo, Eugenia Miranda-Carus, Miguel Ángel López-Nevot, José Luis Vicario, Emilio Martín-Mola, Javier Martín, Dora Pascual-Salcedo Arthritis Research & Therapy 2010, 12:R62 (6 April 2010)
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A crucial role for tumor necrosis factor receptor 1 in synovial lining cells and the reticuloendothelial system in mediating experimental arthritis
Onno J Arntz, Jeroen Geurts, Sharon Veenbergen, Miranda B Bennink, Ben T van den Brand, Shahla Abdollahi-Roodsaz, Wim B van den Berg, Fons A van de Loo Arthritis Research & Therapy 2010, 12:R61 (6 April 2010)
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Attenuation of fibrosis in vitro and in vivo with SPARC siRNA
Jiu-Cun Wang, Syeling Lai, Xinjian Guo, Xuefeng Zhang, Benoit de Crombrugghe, Sonali Sonnylal, Frank C Arnett, Xiaodong Zhou Arthritis Research & Therapy 2010, 12:R60 (1 April 2010)
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Olf1/EBF associated zinc finger protein interfered with antinuclear antibody production in patients with systemic lupus erythematosus
Xuebing Feng, Rongliang Li, Jing Huang, Huayong Zhang, Lina Zhu, Bingzhu Hua, Betty P Tsao, Lingyun Sun Arthritis Research & Therapy 2010, 12:R59 (1 April 2010)
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The association between subchondral bone cysts and tibial cartilage volume and risk of joint replacement in people with knee osteoarthritis: a longitudinal study
Stephanie K Tanamas, Anita E Wluka, Jean-Pierre Pelletier, Johanne Martel-Pelletier, François Abram, Yuanyuan Wang, Flavia M Cicuttini Arthritis Research & Therapy 2010, 12:R58 (31 March 2010)
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Evaluation of the rheumatoid arthritis susceptibility loci HLA-DRB1, PTPN22, OLIG3/TNFAIP3, STAT4 and TRAF1/C5 in an inception cohort
Ann W Morgan, James I Robinson, Philip G Conaghan, Stephen G Martin, Elizabeth MA Hensor, Michael D Morgan, Lori Steiner, Henry A Erlich, Hock-Chye Gooi, Anne Barton, Jane Worthington, Paul Emery, UKRAG Consortium and the YEAR Consortium Arthritis Research & Therapy 2010, 12:R57 (30 March 2010)
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Calcium deposition in osteoarthritic meniscus and meniscal cell culture
Yubo Sun, David R Mauerhan, Patrick R Honeycutt, Jeffrey S Kneisl, H James Norton, Natalia Zinchenko, Edward N Hanley, Helen E Gruber Arthritis Research & Therapy 2010, 12:R56 (30 March 2010)
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Effects of lifestyle physical activity on perceived symptoms and physical function in adults with fibromyalgia: results of a randomized trial
Kevin R Fontaine, Lora Conn, Daniel J Clauw Arthritis Research & Therapy 2010, 12:R55 (30 March 2010)
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Editor’s summary
Encouraging patients with fibromyalgia to undertake ‘Lifestyle Physical Activity’ can markedly increase the average number of steps taken per day and produce clinically relevant reductions in perceived disability and pain.
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B cell depletion in diffuse progressive systemic sclerosis: safety, skin score modification and IL-6 modulation in an up to thirty-six months follow-up open-label trial
Silvia Bosello, Maria De Santis, Gina Lama, Cristina Spanò, Cristiana Angelucci, Barbara Tolusso, Gigliola Sica, Gianfranco Ferraccioli Arthritis Research & Therapy 2010, 12:R54 (25 March 2010)
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Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus
Kamini Shah, Won-Woo Lee, Seung-Hyun Lee, Sang Hyun Kim, Seong Wook Kang, Joe Craft, Insoo Kang Arthritis Research & Therapy 2010, 12:R53 (24 March 2010)
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Myofiber stress-response in myositis: parallel investigations on patients and experimental animal models of muscle regeneration and systemic inflammation
Maurizio Vitadello, Andrea Doria, Elena Tarricone, Anna Ghirardello, Luisa Gorza Arthritis Research & Therapy 2010, 12:R52 (24 March 2010)
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Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis
Rogelio J Palomino-Morales, Tomas R Vazquez-Rodriguez, Orlando Torres, Inmaculada C Morado, Santos Castañeda, Jose A Miranda-Filloy, Jose L Callejas-Rubio, Benjamin Fernandez-Gutierrez, Miguel A Gonzalez-Gay, Javier Martin Arthritis Research & Therapy 2010, 12:R51 (23 March 2010)
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A rational use of glucocorticoids in patients with early arthritis has a minimal impact on bone mass
Monica Ibañez, Ana M Ortiz, Isabel Castrejón, J Alberto García-Vadillo, Inmaculada Carvajal, Santos Castañeda, Isidoro González-Álvaro Arthritis Research & Therapy 2010, 12:R50 (23 March 2010)
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Interferon-γ inhibits interleukin-1β-induced matrix metalloproteinase production by synovial fibroblasts and protects articular cartilage in early arthritis
Charlotte E Page, Shaun Smale, Sara M Carty, Nicholas Amos, Sarah N Lauder, Rhian M Goodfellow, Peter J Richards, Simon A Jones, Nicholas Topley, Anwen S Williams Arthritis Research & Therapy 2010, 12:R49 (22 March 2010)
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B-lymphocyte stimulator/a proliferation-inducing ligand heterotrimers are elevated in the sera of patients with autoimmune disease and are neutralized by atacicept and B-cell maturation antigen-immunoglobulin
Stacey R Dillon, Brandon Harder, Kenneth B Lewis, Margaret D Moore, Hong Liu, Thomas R Bukowski, Nels B Hamacher, Megan M Lantry, Mark Maurer, Cecile M Krejsa, Jeff L Ellsworth, Susan Pederson, Keith B Elkon, Mark H Wener, Maria Dall'Era, Jane A Gross Arthritis Research & Therapy 2010, 12:R48 (19 March 2010)
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Limited educational attainment and radiographic and symptomatic knee osteoarthritis: a cross-sectional analysis using data from the Johnston County (North Carolina) Osteoarthritis Project
Leigh F Callahan, Jack Shreffler, Bernadette C Siaton, Charles G Helmick, Britta Schoster, Todd A Schwartz, Jiu-Chiuan Chen, Jordan B Renner, Joanne M Jordan Arthritis Research & Therapy 2010, 12:R46 (18 March 2010)
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Editor’s summary
After adjustment for known risk factors, educational attainment, as an indicator of socioeconomic status, is associated with symptomatic knee osteoarthritis in both men and women, and with radiographic knee osteoarthritis in women.
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Slit3 inhibits Robo3-induced invasion of synovial fibroblasts in rheumatoid arthritis
Alexandra E Denk, Simone Kaufmann, Klaus Stark, Jörg Schedel, Torsten Lowin, Thomas Schubert, Anja K Bosserhoff Arthritis Research & Therapy 2010, 12:R45 (18 March 2010)
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Development of proteoglycan-induced arthritis depends on T cell-supported autoantibody production, but does not involve significant influx of T cells into the joints
Adrienn Angyal, Colt Egelston, Tamás Kobezda, Katalin Olasz, Anna László, Tibor T Glant, Katalin Mikecz Arthritis Research & Therapy 2010, 12:R44 (18 March 2010)
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Vasculogenesis in rheumatoid arthritis
Zoltán Szekanecz, Alisa E Koch Arthritis Research & Therapy 2010, 12:110 (18 March 2010)
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Effectiveness of adalimumab in treating patients with ankylosing spondylitis associated with enthesitis and peripheral arthritis
Martin Rudwaleit, Pascal Claudepierre, Martina Kron, Sonja Kary, Robert Wong, Hartmut Kupper Arthritis Research & Therapy 2010, 12:R43 (15 March 2010)
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Anticentromere antibody positive Sjögren's Syndrome: a retrospective descriptive analysis
Vasiliki-Kalliopi K Bournia, Konstantina D Diamanti, Panayiotis G Vlachoyiannopoulos, Haralampos M Moutsopoulos Arthritis Research & Therapy 2010, 12:R47 (13 March 2010)
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