Correction: Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus

ar2996 1478-6354 Correction Correction: Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus ShahKamini LeeWon-Woo LeeSeung-Hyun KimHyunSang KangWookSeong CraftJoe KangInsooinsoo.kang@yale.edu

Department of Internal Medicine, Yale University School of Medicine, S525C TAC, 300 Cedar Street, New Haven, Connecticut 06520, USA

Department of Microbiology, College of Medicine, Seoul National University, 28 Yongondong, Chongno-gu, 110-799, Seoul, Republic of Korea

Department of Microbiology, Konkuk University School of Medicine, 322 Danwol-Dong, Chungju, Chungchungbuk-Do 380-701, Republic of Korea

Department of Microbiology, College of Medicine, Kangwon National University, 192-1 Hyoja-Dong, Chunchon, Kangwon-Do 200-701, Republic of Korea

Department of Internal Medicine, College of Medicine, Chungnam National University, 640 Daesa-Dong, Daejeon 301-131, Republic of Korea

Department of Immunobiology, Yale University School of Medicine, 300 Cedar Street, New Haven, Connecticut 06520, USA

Arthritis Research & Therapy 1478-6354 2010 12 3 402 http://arthritis-research.com/content/12/3/402 See related research by Shah et al., http://arthritis-research.com/content/12/2/R53 10.1186/ar299620497616 1252010 2010BioMed Central Ltd

Following publication of our recent article 1, we noticed an error in Figure 4. In part (e), the SLEDAI score for the frequency of CD4+ T cells expressing CCR4 and/or CCR6 in a patient with SLE at the times of low disease activities should be "6", rather than "4". The corrected Figure 4 is given here overleaf as Figure 1.

Figure 1

Patients with SLE have an increased frequency of CD4⁺CCR4⁺CCR6⁺T cells

Patients with SLE have an increased frequency of CD4⁺CCR4⁺CCR6⁺T cells. The frequency of CCR4⁺CCR6⁺CD4⁺T cells in peripheral blood was analyzed in patients with SLE and healthy control subjects by using flow cytometry. (a) Representative dot plots showing CD4⁺T cells expressing CCR4 and CCR6. (b) The frequency (%) of CD4⁺CCR4⁺CCR6⁺T cells in patients with SLE (n = 14) and healthy control subjects (HC, n = 25). (c) Correlation between the frequencies of CD4⁺IL-17⁺T cells and CD4⁺CCR4⁺CCR6⁺T cells in patients with SLE (n = 11). (d) Correlation between the frequency of CD4⁺CCR4⁺CCR6⁺T cells and SLEDAI score in patients with SLE (n = 14). (e) Representative dot plots showing the frequency of CD4⁺T cells expressing CCR4 and/or CCR6 in patients with SLE at the times of high and low disease activities (SLEDAI score, 16 and 6, respectively). Representative data from three patients with SLE. Numbers in dot plots indicate the frequency of cells for each quadrant. Bars show the means.

Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosusShahKLeeWWLeeSHKimSHKangSWCraftJKangIArthritis Research & Therapy201012R5310.1186/ar2964288820220334681