Table 3 |
|
|
PTPN22 R620W polymorphism and links with immune diseases |
|
|
Association identified |
No association |
|
|
|
|
Scleroderma: ATA positive and ACA positive |
Multiple sclerosis |
|
RA and JRA |
Coeliac disease |
|
SLE |
Primary sclerosis cholangitis |
|
Type I diabetes mellitus |
Crohn's disease |
|
Grave's and Addison's |
Psoriasis |
|
Psoriatic arthritis |
Ankylosing spondylitis |
|
Wegener's granulomatosis |
Primary Sjögren's syndrome |
|
|
|
|
This area of research is reviewed by Gregersen and Batliwalla [18]. ACA, anticentromere antibody; ATA, antitopoisomerase antibody; JRA, juvenile rheumatoid arthritis; RA, rheumatoid arthritis; SLE, systemic lupus erythematosus. |
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|
Mayes and Trojanowska Arthritis Research & Therapy 2007 9(Suppl 2):S5 doi:10.1186/ar2189 |
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