Table 1

Selected genes induced by keratinocyte-fibroblast interactions

Type of gene

Details


Extracellular matrix (ECM)

Collagens

Hyaluronan synthase 2

Lysylhydroxylase 2

Transglutaminase 2

Tenascin C

Decorin

Syndecan 2

Cell-cell signalling

Monocyte chemoattractant protein (MCP)-1

Activin A

Latent TGF-β-binding protein (LTBP)1

Interleukin (IL)-6

Connective tissue growth factor (CTGF)

Heparin-binding epithelial growth factor (HB-EGF)

Endothelin (ET)-1

Angiopoietin 1

Cyclo-oxygenase (COX)-2

Granulocyte-colony stimulating factor (G-CSF)

Cytoskeleton

α-Smooth muscle actin (α-SMA)

Integrins

Tropomyosin

Vasodilator-stimulated phosphoprotein (VASP)

Myosin light chain kinase (MLCK)


Taken from [30].

Krieg et al. Arthritis Research & Therapy 2007 9(Suppl 2):S4   doi:10.1186/ar2188