Table 1 |
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|
Selected genes induced by keratinocyte-fibroblast interactions |
|
|
Type of gene |
Details |
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|
|
|
Extracellular matrix (ECM) |
Collagens |
|
Hyaluronan synthase 2 |
|
|
Lysylhydroxylase 2 |
|
|
Transglutaminase 2 |
|
|
Tenascin C |
|
|
Decorin |
|
|
Syndecan 2 |
|
|
Cell-cell signalling |
Monocyte chemoattractant protein (MCP)-1 |
|
Activin A |
|
|
Latent TGF-β-binding protein (LTBP)1 |
|
|
Interleukin (IL)-6 |
|
|
Connective tissue growth factor (CTGF) |
|
|
Heparin-binding epithelial growth factor (HB-EGF) |
|
|
Endothelin (ET)-1 |
|
|
Angiopoietin 1 |
|
|
Cyclo-oxygenase (COX)-2 |
|
|
Granulocyte-colony stimulating factor (G-CSF) |
|
|
Cytoskeleton |
α-Smooth muscle actin (α-SMA) |
|
Integrins |
|
|
Tropomyosin |
|
|
Vasodilator-stimulated phosphoprotein (VASP) |
|
|
Myosin light chain kinase (MLCK) |
|
|
|
|
|
Taken from [30]. |
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|
Krieg et al. Arthritis Research & Therapy 2007 9(Suppl 2):S4 doi:10.1186/ar2188 |
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