Table 1 |
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Some proangiogenic mediators involved in the pathogenesis of rheumatoid arthritis |
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Type of molecule |
Molecule |
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Growth factors |
Fibroblast growth factor (FGF)-2 |
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Transforming growth factor (TGF)-β |
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Hepatocyte growth factor (HGF) |
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Vascular endothelial growth factors (VEGF, VEGF-C, and VEGF-D) |
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|
Cytokines |
Tumour necrosis factor (TNF)-α |
|
Platelet activating factor (PAF) |
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|
Angiopoietin (Ang)-1, Ang-2 |
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|
Chemokines |
Interleukin (IL)-8 |
|
Epithelial neutrophil activating peptide (ENA)-78 |
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|
Growth related gene product (GRO)-α |
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Stromal cell derived factor (SDF)-1 |
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|
Fractalkine |
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|
Other mediators |
Endothelin (ET)-1 |
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|
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Koch and Distler Arthritis Research & Therapy 2007 9(Suppl 2):S3 doi:10.1186/ar2187 |
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