|
Some proangiogenic mediators involved in the pathogenesis of rheumatoid arthritis |
|
| Type of molecule |
Molecule |
|
|
|
| Growth factors |
Fibroblast growth factor (FGF)-2 |
| Transforming growth factor (TGF)-β |
|
| Hepatocyte growth factor (HGF) |
|
| Vascular endothelial growth factors (VEGF, VEGF-C, and VEGF-D) |
|
| Cytokines |
Tumour necrosis factor (TNF)-α |
| Platelet activating factor (PAF) |
|
| Angiopoietin (Ang)-1, Ang-2 |
|
| Chemokines |
Interleukin (IL)-8 |
| Epithelial neutrophil activating peptide (ENA)-78 |
|
| Growth related gene product (GRO)-α |
|
| Stromal cell derived factor (SDF)-1 |
|
| Fractalkine |
|
| Other mediators |
Endothelin (ET)-1 |
Koch and Distler Arthritis Research & Therapy 2007 9(Suppl 2):S3 doi:10.1186/ar2187 |
|