Figure 4.
Effect of RANKL blockade on experimental arthritis. Adjuvant-induced arthritis of rats treated with vehicle or osteoprotegerin (OPG). Note the protection of bone and the absence of (stained) osteoclasts. RANKL, receptor activator of nuclear factor-κB ligand.
Schett Arthritis Research & Therapy 2007 9(Suppl 1):S2 doi:10.1186/ar2166