|
Reported pregnancy histories at the time of survey among women who had ever been pregnant |
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| Ever pregnant women with SLE (n = 97) |
Ever pregnant women without SLE (n = 184) |
P valuea |
|
|
|
|||
| Total number of reported pregnancies per woman |
0.50 |
||
| 1 |
13 (13%) |
20 (11%) |
|
| 2 |
20 (21%) |
36 (20%) |
|
| 3 |
21 (22%) |
47 (26%) |
|
| 4 |
19 (20%) |
29 (16%) |
|
| 5 |
10 (10%) |
23 (13%) |
|
| ≥ 6 |
14 (14%) |
29 (15%) |
|
| Mean (standard deviation) number of pregnancies |
3.7 (2.0) |
3.7 (2.4) |
|
| Mean (standard deviation) age at first pregnancy (years) |
22.1 (4.8) |
22.5 (4.8) |
0.55 |
| Ever had a live birth – total number of live births reported per woman |
0.12 |
||
| 0 |
7 (7%) |
2 (1%) |
|
| 1 |
20 (21%) |
34 (18%) |
|
| 2 |
22 (23%) |
40 (22%) |
|
| 3 |
24 (25%) |
51 (28%) |
|
| 4 |
11 (11%) |
25 (14%) |
|
| ≥ 5 |
13 (13%) |
32 (17%) |
|
| Median (P5–P95)b live births |
2.5 (0–5) |
3 (1–5) |
|
| Ever miscarried – total number of miscarriagesc reported per woman |
0.07 |
||
| 0 |
51 (53%) |
125 (68%) |
|
| 1 |
30 (31%) |
35 (19%) |
|
| 2 |
11 (11%) |
15 (8%) |
|
| ≥ 3 |
5 (5%) |
9 (5%) |
|
| Median (P5–P95)b miscarriagesc |
0.5 (0–3) |
0 (0–3) |
|
| Ever had a stillbirth – total number of stillbirths reported per woman |
0.01 |
||
| 0 |
86 (89%) |
175 (95%) |
|
| 1 |
7 (7%) |
9 (5%) |
|
| ≥ 2 |
4 (4%) |
0 |
|
| Median (P5–P95)b stillbirths |
0 (0–1.25) |
0 (0–0.75) |
|
| Ever had an ectopic pregnancy |
0.17 |
||
| 0 |
92 (95%) |
180 (98%) |
|
| 1 |
5 (5%) |
3 (2%) |
|
| ≥ 2 |
0 |
1 (0.5%) |
|
| Median (P5–P95)b ectopic |
0 (0–1) |
0 (0–0) |
|
| Women with a SLE diagnosis only |
|||
| First pregnancy before SLE diagnosis |
78 (80%) |
- |
- |
| First pregnancy after SLE diagnosis |
19 (20%) |
||
| Age (years) at first pregnancy |
|||
| Mean (standard deviation) age at first pregnancy if before SLE diagnosis |
22.1 (4.6) |
- |
- |
| Mean (standard deviation) age at first pregnancy if after SLE diagnosis |
26.6 (7.0) |
||
| Number of reported pregnancies per woman |
|||
| Mean (standard deviation) pregnancies whose first conception was before SLE diagnosis |
3.7 (2.1) |
- |
- |
| Mean (standard deviation) pregnancies whose first conception was after SLE diagnosis |
3.6 (2.7) |
||
|
aFrom chi-squared test for heterogeneity, detecting differences between women with systemic lupus erythematosus (SLE) and those without SLE. bFifth to 95th centiles – the central 90% of the distribution. c Includes missed abortions (missed miscarriages) and blighted ova. | |||
Molokhia et al. Arthritis Research & Therapy 2007 9:R124 doi:10.1186/ar2332 |
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