Open Access Highly Accessed Research article

Activation of proteinase-activated receptor 2 in human osteoarthritic cartilage upregulates catabolic and proinflammatory pathways capable of inducing cartilage degradation: a basic science study

Christelle Boileau*, Nathalie Amiable, Johanne Martel-Pelletier, Hassan Fahmi, Nicolas Duval and Jean-Pierre Pelletier

Arthritis Research & Therapy 2007, 9:R121 doi:10.1186/ar2329

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