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Serum paraproteins in the case–control study of 74 age-matched and connective tissue disease (CTD) diagnosis-matched women with and without silicone implants |
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| Silicone implant |
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|
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| Yes (Group 1) |
No (Group 2) |
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| Age (years)a |
49.9 ± 8.7 |
49.8 ± 8.4 |
| Number of women with paraprotein band(s)/totalb |
7/74 (9.5%) |
4/74 (5.4%) |
| Number of women with paraprotein band(s) according to primary CTD diagnosis |
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| Unexplained polyarthritis |
0/1 (0%) |
0/1 (0%) |
| Systemic sclerosis |
1/10 (10%) |
0/10 (0%) |
| Systemic lupus erythematosus |
0/1 (0%) |
0/0 (0%) |
| Polymyositis/dermatomyositis |
1/13 (4%) |
2/14 (4%) |
| Undifferentiated CTD |
4/39 (13%) |
2/39 (5%) |
| Fibromyalgia syndrome |
1/10 (0%) |
0/10 (10%) |
| Type of paraprotein band(s)c |
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| IgG(κ) |
4 |
5 |
| IgG(λ) |
1 |
1 |
| IgM(κ) |
0 |
0 |
| IgM(λ) |
2 |
1 |
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aPresented as the mean ± standard deviation, no significant difference by paired t test (P = 0.82). bNo significant differences between Groups 1 and 2 using the McNemar test (P = 0.55). cOne woman with dermatomyositis had two IgG(κ) and one IgG(λ) bands, whereas a patient with polymyositis had both IgG(κ) and IgM(λ) bands. | ||
Csako et al. Arthritis Research & Therapy 2007 9:R95 doi:10.1186/ar2295 |
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