|
Mankin's histological histochemical grading |
|
| Category |
Grade |
|
|
|
| I. Structure |
|
| Normal |
0 |
| Surface irregularities |
1 |
| Pannus and surface irregularities |
2 |
| Clefts to transitional zone |
3 |
| Clefts to radial zone |
4 |
| Clefts to calcified zone |
5 |
| Complete disorganization |
6 |
| II. Cells |
|
| Normal |
0 |
| Diffuse hypercellularity |
1 |
| Cloning |
2 |
| Hypocellularity |
3 |
| III. Safranin-O staining |
|
| Normal |
0 |
| Slightly reduced |
1 |
| Moderate reduced |
2 |
| Severe reduced |
3 |
| No dye noted |
4 |
| IV. Tidemark integrity |
|
| Intact |
0 |
| Crossed by blood vessels |
1 |
Hattori et al. Arthritis Research & Therapy 2007 9:R88 doi:10.1186/ar2287 |
|