Figure 3.

Comparison of anti-collagen IgG isotypes in DBA/1 and B6 mice with collagen-induced arthritis. Serum from naïve and arthritic mice were analysed for anti-collagen antibodies. IgG1 (a) and IgG2a/c (b) anti-collagen isotypes were quantified in naïve mice and mice with early (up to 2 weeks after onset) and late (6 to 8 weeks after onset) arthritis after immunisation (n = 8). *P < 0.05, **P < 0.01.